Search results:
General Information
| Gene_Symbol | Gene_ID | Gene_Name | Chromosome | Alias |
|---|---|---|---|---|
| IGFBP2 | 3485 | insulin-like growth factor binding protein 2, 36kDa | 2 |
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 20157191 | 2010 | Cell line : - Source : National Taiwan University Hospital Sample Type : CRC tumor and normal tissue No. of Sample : 162 CRC before surgery, in paired 15 patients, in 24 patients with advanced colon polyps, and in 114 healthy controls Stage : TNM Stage I-IV | ELISA | Up-regulation | - | IGFBP-2 is a potential diagnostic and prognostic biomarker of CRC. |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | |
| Description | - |
| Chromosome | 2 |
| Location | 2q35 |
| Start | 216633404 |
| End | 216664436 |
| Strand | + |
| Gene Sequence | Download Select all |
| Length | 31033 |
| OMIM ID | 146731 |
| HGNC ID | HGNC:5471 |
| Unigene ID | Hs.438102 |
| Ensembl ID | ENSG00000115457 |
| PharmGKB ID | - |
mRNA Information
| mRNA ID | NM_000597.2 |
|---|---|
| Exon | join(1..562,27154..27383,28455..28595,30537..31033) | mRNA Sequence | Download Select all |
| Length | 1439 |
CDS Information
| Location | join(121..562,27154..27383,28455..28595,30537..30701) |
|---|---|
| CDS Sequence | Download Select all |
| CCDS ID | CCDS42815.1 |
Protein Information
| Protein ID | NP_000588.2 |
|---|---|
| Protein Name | insulin-like growth factor binding protein 2, 36kDa |
| Molecular Wt. (Da) | 31447 |
| Protein Sequence | Download Select all |
| Length | 328 |
| Uniprot ID | P51858 |
| Ensembl Protein ID | ENSP00000349878 |
Post-translational Modification Information (Source : HPRD)
No matching records could be found.
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
No matching records from HPRD source could be found.
Pathway Information
No matching records could be found.
Structure Information
| PDB ID | 2H7T |
|---|---|
| Resolution | |
| Method | SOLUTION NMR |
| Chains | A |
| Molecule | Insulin-like growth factor-binding protein 2 |
| Model | View |
Domain Information
| ID | Location | Description |
|---|---|---|
| cd00191 | 226-306 | TY |
| cl00150 | 226-306 | TY superfamily |
| smart00121 | 40-132 | IB |
| cl02472 | 40-132 | IGFBP superfamily |
| pfam00086 | 227-306 | Thyroglobulin_1 |
| pfam00219 | 74-111 | IGFBP |
| smart00211 | 258-307 | TY |
Ontology Information
| HPRD ID | 3204 |
|---|---|
| Molecular Class | Secreted polypeptide |
| Molecular Function | ATPase activity (GO:0016887) |
| Biological Process | Cell communication (GO:0007154); Signal transduction (GO:0007165) |
Drug Information
No matching records could be found.