Search results:
General Information
| Gene_Symbol | Gene_ID | Gene_Name | Chromosome | Alias |
|---|---|---|---|---|
| EIF3E | 3646 | eukaryotic translation initiation factor 3, subunit E | 8 | eIF3-p48, eIF3e |
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 25400724 | 2014 | Cell line : - Source : Shanghai Jiaotong University Affiliated First Peoples Hospital Sample Type : CRC tumor and normal tissue No. of Sample : 173 Stage : - | real time RT-PCR, Tissue microarray, immunohistochemistry | Up-regulation | - | - |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | - |
| Description | - |
| Chromosome | 8 |
| Location | 8q22-q23 |
| Start | 109213972 |
| End | 109260959 |
| Strand | - |
| Gene Sequence | Download Select all |
| Length | 46988 |
| OMIM ID | 602210 |
| HGNC ID | HGNC:3277 |
| Unigene ID | Hs.405590 |
| Ensembl ID | ENSG00000104408 |
| PharmGKB ID | PA27705 |
mRNA Information
| mRNA ID | NM_001568.2 |
|---|---|
| Exon | join(1..118,6818..6932,8656..8773,12528..12570, 13629..13733,19536..19661,20340..20464,31271..31397, 32218..32319,34015..34124,45228..45330,45614..45748, 46808..46988) | mRNA Sequence | Download Select all |
| Length | 1516 |
Protein Information
| Protein ID | NP_001559.1 |
|---|---|
| Protein Name | eukaryotic translation initiation factor 3, subunit E |
| Molecular Wt. (Da) | 52090 |
| Protein Sequence | Download Select all |
| Length | 445 |
| Uniprot ID | P04179 |
| Ensembl Protein ID | ENSP00000442920 |
Post-translational Modification Information (Source : HPRD)
| Residue | Type | site |
|---|---|---|
| S | Phosphorylation | 399 |
| K | Acetylation | 275 |
| T | Phosphorylation | 161 |
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
| Interactant Gene ID (Source: HPRD) | Gene Symbol | HPRD ID | Ref Seq ID | Technique | References |
|---|---|---|---|---|---|
| 3434 | IFIT1 | 983 | NP_001539.3 | in vitro;in vivo;yeast 2-hybrid | 1 064 436 211 118 220 |
| 4093 | SMAD9 | 4484 | BAA21128.1 | yeast 2-hybrid | 15231748 |
| 4905 | NSF | 3380 | NP_006169.2 | yeast 2-hybrid | 16169070 |
| 7916 | BAT2 | 807 | NP_542417.2 | yeast 2-hybrid | 14667819 |
| 8733 | GPAA1 | 4334 | NP_003792.1 | yeast 2-hybrid | 16169070 |
| 9001 | HAP1 | 2972 | NP_003940.3 | yeast 2-hybrid | 16169070 |
| 10900 | RUNDC3A | 16106 | NP_001138297.1 | yeast 2-hybrid | 16189514 |
| 57062 | DDX24 | 5860 | NP_065147.1 | yeast 2-hybrid | 16169070 |
| 60313 | GPBP1L1 | 15418 | NP_067652.1 | yeast 2-hybrid | 16189514 |
Pathway Information
| Pathway Name | Pathway ID |
|---|---|
| Hepatitis C | hsa05160 |
| RNA transport | hsa03013 |
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| pfam09440 | 5-138 | eIF3_N |
| cl09680 | 5-138 | eIF3_N superfamily |
| pfam01399 | 290-394 | PCI |
| cl02111 | 290-394 | PCI superfamily |
| smart00753 | 328-411 | PAM |
| smart00088 | 328-411 | PINT |
Ontology Information
| HPRD ID | 1678 |
|---|---|
| Molecular Class | Translation regulatory protein |
| Molecular Function | Transcription factor activity (GO:0003700) |
| Biological Process | Regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism (GO:0019219) |
Drug Information
No matching records could be found.