Search results:
General Information
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 23612070    | 2013 | Cell line : - Source : - Sample Type : Fresh-frozen CRC tissues No. of Sample : 19 nonresponders and 16 responders CRC Stage : TNM stage III | RT-PCR, microRNA arrays | Down-regulation | 2 Fold | - |
Gene Details

| Gene Type | protein coding |
|---|---|
| Gene Family | Ion channels / Aquaporins |
| Description | The aquaporins are a family of water-selective membrane channels. The protein encoded by this gene allows passage of a wide variety of noncharged solutes. It stimulates urea transport and osmotic water permeability; there are contradicting reports about its role in providing glycerol permeability. The encoded protein may also play a role in specialized leukocyte functions such as immunological response and bactericidal activity. [provided by RefSeq, Jul 2008]   |
| Chromosome | 15 |
| Location | 15q |
| Start | 58430374   |
| End | 58478110   |
| Strand | +   |
| Gene Sequence |    Download   Select all |
| Length | 47737   |
| OMIM ID | 602914    |
| HGNC ID | HGNC:643    |
| Unigene ID | Hs.104624    |
| Ensembl ID | ENSG00000103569    |
| PharmGKB ID | PA24927    |
mRNA Information
| mRNA ID | NM_020980.3 |
|---|---|
| Exon | join(1..468,28465..28591,34860..34997,36710..36828, 40920..41137,45753..47703)   | mRNA Sequence |    Download   Select all |
| Length | 3033   |
CDS Information
| Location | 358..1245 |
|---|---|
| CDS Sequence |    Download   Select all |
| CCDS ID | CCDS10165.1 |    
Protein Information
| Protein ID | NP_066190.2 |
|---|---|
| Protein Name | aquaporin 9 |
| Molecular Wt. (Da) | 31300 |
| Protein Sequence |    Download   Select all |
| Length | 295   |
| Uniprot ID | P08582 |    
| Ensembl Protein ID | ENSP00000296350   |    
Post-translational Modification Information (Source : HPRD)
| Residue | Type | site |
|---|---|---|
| S | Phosphorylation | 222;- |
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING)      View   
No matching records from HPRD source could be found.
Pathway Information
| Pathway Name | Pathway ID |
|---|---|
| Bile secretion |    hsa04976 |    
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| cd00333 | 24-265  | MIP |
| cl00200 | 24-265  | MIP superfamily |
| PTZ00016 | 1-266  | PTZ00016 |
| COG0580 | 19-266  | GlpF |
| TIGR00861 | 28-262  | MIP |
| pfam00230 | 19-262  | MIP |
| PLN00183 | 23-271  | PLN00183 |
| PRK05420 | 22-267  | PRK05420 |
| PLN00182 | 22-265  | PLN00182 |
| PLN00026 | 21-265  | PLN00026 |
| PLN00184 | 24-265  | PLN00184 |
| PLN00166 | 24-262  | PLN00166 |
| PLN00027 | 23-273  | PLN00027 |
| PLN00167 | 27-262  | PLN00167 |
| TIGR00861 | 27-117  | MIP |
Ontology Information
| HPRD ID | 5096 |    
|---|---|
| Molecular Class | Water channel |
| Molecular Function | Molecular function unknown (GO:0005554) |
| Biological Process | Biological_process unknown (GO:0000004)   |
Drug Information
No matching records could be found.
External Links
| ArrayExpress | GO |    
|---|---|
| ICGC | GO |    
| Cancer3D | GO |    
| COSMIC | GO |    
| NCG | GO |    
| TSGene | GO |    
| Tumor Gene Family of Databases | GO |    
| CCDB | GO |    
| G2SBC | GO |    
| Osteosarcoma Database | GO |    
| RCDB | GO |    
