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General Information



Gene_Symbol Gene_ID Gene_Name Chromosome Alias
AQP9 366 aquaporin 9  15SSC1, HsT17287 







  • Evidence
  • Gene
  • mRNA
  • CDS
  • Protein
  • PTM
  • Enzyme
  • PPi
  • Pathway
  • Structural
  • Domain
  • Ontology
  • SNP
  • Drug
  • External Links



Evidence Information


Pubmed ID Year Sample Information Techniques Mechanism Fold Change Remark
23612070   2013Cell line : -

Source : -

Sample Type : Fresh-frozen CRC tissues

No. of Sample : 19 nonresponders and 16 responders CRC

Stage : TNM stage III

RT-PCR, microRNA arraysDown-regulation2 Fold-


Gene Details



NC_000015.9 (58430374..58478110)

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Gene Type protein coding
Gene Family Ion channels / Aquaporins
Description The aquaporins are a family of water-selective membrane channels. The protein encoded by this gene allows passage of a wide variety of noncharged solutes. It stimulates urea transport and osmotic water permeability; there are contradicting reports about its role in providing glycerol permeability. The encoded protein may also play a role in specialized leukocyte functions such as immunological response and bactericidal activity. [provided by RefSeq, Jul 2008]  
Chromosome 15
Location 15q
Start 58430374  
End 58478110  
Strand +  
Gene Sequence

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Length 47737  
OMIM ID 602914   
HGNC ID HGNC:643   
Unigene ID Hs.104624   
Ensembl ID ENSG00000103569   
PharmGKB ID PA24927   

mRNA Information


mRNA ID NM_020980.3
Exon join(1..468,28465..28591,34860..34997,36710..36828, 40920..41137,45753..47703)  
mRNA Sequence

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Length 3033  



CDS Information


   
Location358..1245
CDS Sequence

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CCDS ID CCDS10165.1



Protein Information


      
Protein IDNP_066190.2
Protein Nameaquaporin 9
Molecular Wt. (Da)31300
Protein Sequence

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Length 295  
Uniprot IDP08582
Ensembl Protein ID ENSP00000296350  



Post-translational Modification Information (Source : HPRD)


Residue Type site
SPhosphorylation222;-

Enzyme Information


No matching records could be found.

PPi Information


(Click to view network : Source STRING)      View   

No matching records from HPRD source could be found.

Pathway Information


      
Pathway Name Pathway ID
Bile secretion hsa04976


Structure Information


No matching records could be found.

Domain Information




ID Location Description
cd0033324-265  MIP
cl0020024-265  MIP superfamily
PTZ000161-266  PTZ00016
COG058019-266  GlpF
TIGR0086128-262  MIP
pfam0023019-262  MIP
PLN0018323-271  PLN00183
PRK0542022-267  PRK05420
PLN0018222-265  PLN00182
PLN0002621-265  PLN00026
PLN0018424-265  PLN00184
PLN0016624-262  PLN00166
PLN0002723-273  PLN00027
PLN0016727-262  PLN00167
TIGR0086127-117  MIP


Ontology Information


   
HPRD ID5096
Molecular ClassWater channel
Molecular FunctionMolecular function unknown (GO:0005554)
Biological ProcessBiological_process unknown (GO:0000004)  



SNP Information


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Drug Information


No matching records could be found.

External Links


                                 
ArrayExpressGO
ICGCGO
Cancer3DGO
COSMICGO
NCGGO
TSGeneGO
Tumor Gene Family of DatabasesGO
CCDBGO
G2SBCGO
Osteosarcoma DatabaseGO
RCDBGO