Search results:
General Information
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 22121102 | 2013 | Cell line : SW1116, HT29 Source : - Sample Type : - No. of Sample : - Stage : - | Genotyping. | Polymorhpism | - | Association between genetic variation in JAK1 (10 SNPs) with risk of colorectal cancer were observed. |
| 18320073 | 2008 | Cell line : - Source : Twin Cities Metropolitan Area, Kaiser Permanente Medical Care Program of Northern California (KPMCP) and a seven-county area of Utah . Sample Type : Population based case-control study No. of Sample : Colon cancer 1555, 1,956 controls rectal cancer 754, 959 controls Stage : - | Immunohistochemistry, Western Blotting, Cell Viability Assay, Flow Cytometry,In Vitro Invasion Assay, Tissue Microarray | Up-regulation | - | STAT3 and both JAK1 and 2 are involved in CRC cell growth, survival, invasion, and migration through regulation of gene expression, such as Bcl-2, p1(6ink4a), p21(waf1/cip1), p27(kip1), E-cadherin, VEGF, and MMPs. |
| 24195509 | 2014 | Cell line : DLD 1, RKO Source : - Sample Type : - No. of Sample : - Stage : - | Trypan blue exclusion assay, annexin V staining, western blotting | Up-regulation | - | The use of selective JAK1 inhibitors could be an attractive therapy against colorectal cancer. |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | - |
| Description | Janus kinase 1 (JAK1), is a member of a new class of protein-tyrosine kinases (PTK) characterized by the presence of a second phosphotransferase-related domain immediately N-terminal to the PTK domain. The second phosphotransferase domain bears all the hallmarks of a protein kinase, although its structure differs significantly from that of the PTK and threonine/serine kinase family members. JAK1 is a large, widely expressed membrane-associated phosphoprotein. JAK1 is involved in the interferon-alpha/beta and -gamma signal transduction pathways. The reciprocal interdependence between JAK1 and TYK2 activities in the interferon-alpha pathway, and between JAK1 and JAK2 in the interferon-gamma pathway, may reflect a requirement for these kinases in the correct assembly of interferon receptor complexes. These kinases couple cytokine ligand binding to tyrosine phosphorylation of various known signaling proteins and of a unique family of transcription factors termed the signal transducers and activators of transcription, or STATs. [provided by RefSeq, Jul 2008] |
| Chromosome | 1 |
| Location | 1p32.3-p31 |
| Start | 65298906 |
| End | 65432593 |
| Strand | - |
| Gene Sequence | Download Select all |
| Length | 133688 |
| OMIM ID | 147795 |
| HGNC ID | HGNC:6190 |
| Unigene ID | Hs.207538 |
| Ensembl ID | ENSG00000162434 |
| PharmGKB ID | PA29988 |
mRNA Information
| mRNA ID | XM_006710738.2 |
|---|---|
| Exon | complement(<133679..>133688) | mRNA Sequence | Download Select all |
| Length | 4532 |
Protein Information
| Protein ID | XP_006710801.2 |
|---|---|
| Protein Name | Janus kinase 1 |
| Molecular Wt. (Da) | 130543 |
| Protein Sequence | Download Select all |
| Length | 691 |
| Uniprot ID | Q9Y5Y6 |
| Ensembl Protein ID | ENSP00000278742 |
Post-translational Modification Information (Source : HPRD)
| Residue | Type | site |
|---|---|---|
| Y | Dephosphorylation | 1034 |
| Y | Dephosphorylation | 1035 |
| Y | Phosphorylation | 1034 |
| Y | Phosphorylation | 1035 |
| Y | Dephosphorylation | 1034 |
| Y | Dephosphorylation | 1035 |
| T | Phosphorylation | 687 |
| T | Phosphorylation | 688 |
| T | Phosphorylation | 1107 |
| T | Phosphorylation | 119 |
| S | Phosphorylation | 125 |
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
| Interactant Gene ID (Source: HPRD) | Gene Symbol | HPRD ID | Ref Seq ID | Technique | References |
|---|---|---|---|---|---|
| 672 | BRCA1 | 218 | NP_009231.2 | in vivo | 11163768 |
| 1439 | CSF2RB | 739 | NP_000386.1 | in vivo | 11557047 |
| 1441 | CSF3R | 737 | NP_724781.1 | in vitro;in vivo | 7512720 |
| 2242 | FES | 1814 | NP_001996.1 | in vivo | 11160325 |
| 2885 | GRB2 | 150 | NP_002077.1 | in vivo | 115 273 828 536 716 |
| 3459 | IFNGR1 | 127 | NP_000407.1 | in vivo | 12133952 |
| 3480 | IGF1R | 932 | NP_000866.1 | in vitro;in vivo | 9492017 |
| 3560 | IL2RB | 896 | NP_000869.1 | in vivo | 7 973 659 121 339 520 000 000 |
| 3563 | IL3RA | 2392 | NP_002174.1 | in vivo | 15988755 |
| 3566 | IL4R | 990 | NP_000409.1 | in vitro;in vivo | 12133952 |
| 3587 | IL10RA | 911 | NP_001549.2 | in vitro;in vivo | 121 339 521 237 481 000 000 000 |
| 3635 | INPP5D | 9033 | NP_001017915.1 | in vivo | 10875931 |
| 3667 | IRS1 | 943 | NP_005535.1 | in vitro;in vivo | 11162588 |
| 5156 | PDGFRA | 1429 | NP_006197.1 | in vitro | 11468294 |
| 5159 | PDGFRB | 1423 | NP_002600.1 | in vitro;in vivo | 86 571 519 484 840 |
| 5321 | PLA2G4A | 8986 | NP_077734.1 | in vivo | 8612580 |
| 5336 | PLCG2 | 2570 | AAH11772.1 | in vivo | 14978237 |
| 5590 | PRKCZ | 1504 | NP_002735.3 | in vitro;in vivo | 15526032 |
| 5777 | PTPN6 | 1475 | NP_536859.1 | in vitro | 76 291 319 520 455 |
| 6772 | STAT1 | 2777 | NP_009330.1 | in vitro;in vivo | 1 172 259 276 576 600 000 000 000 000 000 000 000 000 000 000 000 000 000 000 000 000 000 000 000 000 000 000 000 |
| 6773 | STAT2 | 2778 | NP_005410.1 | in vitro;in vivo | 9020188 |
| 6774 | STAT3 | 26 | NP_644805.1 | in vitro;in vivo | 117 225 921 194 057 000 000 000 000 000 000 000 000 000 000 000 000 000 000 000 000 000 000 000 000 000 000 000 000 000 000 |
| 6778 | STAT6 | 3302 | NP_003144.3 | in vitro | 10856136 |
| 7297 | TYK2 | 1490 | NP_003322.3 | in vitro;in vivo | 75 895 628 702 790 |
| 7852 | CXCR4 | 1217 | NP_001008540.1 | in vivo | 12163560 |
| 9021 | SOCS3 | 5006 | NP_003946.3 | in vivo | 10707961 |
| 10603 | SH2B2 | 16097 | NP_066189.3 | in vivo | 11751854 |
| 152789 | JAKMIP1 | 11292 | NP_001092903.1 | in vitro;in vivo | 15277531 |
Pathway Information
| Pathway Name | Pathway ID |
|---|---|
| Epstein-Barr virus infection | hsa05169 |
| Hepatitis B | hsa05161 |
| Hepatitis C | hsa05160 |
| Herpes simplex infection | hsa05168 |
| HTLV-I infection | hsa05166 |
| Influenza A | hsa05164 |
| Jak-STAT signaling pathway | hsa04630 |
| Leishmaniasis | hsa05140 |
| Measles | hsa05162 |
| Osteoclast differentiation | hsa04380 |
| Pancreatic cancer | hsa05212 |
| Pathways in cancer | hsa05200 |
| PI3K-Akt signaling pathway | hsa04151 |
| Signaling pathways regulating pluripotency of stem cells | hsa04550 |
| Toxoplasmosis | hsa05145 |
| Tuberculosis | hsa05152 |
| Viral carcinogenesis | hsa05203 |
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| cd05079 | 870-1153 | PTKc_Jak1_rpt2 |
| cl21453 | 870-1153 | PKc_like superfamily |
| cd05077 | 583-846 | PTK_Jak1_rpt1 |
| cl21453 | 583-846 | PKc_like superfamily |
| cd13332 | 282-426 | FERM_C_JAK1 |
| cl17171 | 282-426 | PH-like superfamily |
| cd05038 | 870-1153 | PTKc_Jak_rpt2 |
| cd05080 | 870-1152 | PTKc_Tyk2_rpt2 |
| cd05076 | 583-845 | PTK_Tyk2_rpt1 |
| cd05037 | 583-846 | PTK_Jak_rpt1 |
| cd05081 | 870-1152 | PTKc_Jak3_rpt2 |
| cd14205 | 870-1145 | PTKc_Jak2_rpt2 |
| cd05078 | 583-846 | PTK_Jak2_rpt1 |
| cd14208 | 583-846 | PTK_Jak3_rpt1 |
| cd00192 | 881-1150 | PTKc |
| cd05060 | 879-1149 | PTKc_Syk_like |
| cd05034 | 879-1150 | PTKc_Src_like |
| cd05040 | 881-1147 | PTKc_Ack_like |
| cd05068 | 871-1145 | PTKc_Frk_like |
| cd10378 | 426-527 | SH2_Jak1 |
| cl15255 | 426-527 | SH2 superfamily |
| cd05056 | 875-1145 | PTKc_FAK |
| cd05057 | 875-1154 | PTKc_EGFR_like |
| cd05041 | 879-1142 | PTKc_Fes_like |
| cd13999 | 881-1147 | STKc_MAP3K-like |
| cd05032 | 875-1147 | PTKc_InsR_like |
| cd05049 | 869-1145 | PTKc_Trk |
| cd05044 | 881-1151 | PTKc_c-ros |
| cd05053 | 881-1153 | PTKc_FGFR |
| cd05039 | 872-1152 | PTKc_Csk_like |
| cd05099 | 879-1153 | PTKc_FGFR4 |
| cd05048 | 873-1145 | PTKc_Ror |
| cd05051 | 875-1145 | PTKc_DDR |
| cd05148 | 879-1147 | PTKc_Srm_Brk |
| cd05116 | 880-1142 | PTKc_Syk |
| cd05115 | 880-1145 | PTKc_Zap-70 |
| cd05058 | 879-1153 | PTKc_Met_Ron |
| cd05046 | 869-1146 | PTK_CCK4 |
| cd05108 | 875-1154 | PTKc_EGFR |
| cd05092 | 869-1145 | PTKc_TrkA |
| cd05033 | 881-1153 | PTKc_EphR |
| cd05067 | 875-1149 | PTKc_Lck_Blk |
| cd05052 | 881-1152 | PTKc_Abl |
| cd05072 | 875-1149 | PTKc_Lyn |
| cd05059 | 875-1147 | PTKc_Tec_like |
| cd05045 | 881-1153 | PTKc_RET |
| cd05098 | 879-1153 | PTKc_FGFR1 |
| cd05109 | 875-1154 | PTKc_HER2 |
| cd05082 | 875-1150 | PTKc_Csk |
| cd05050 | 878-1142 | PTKc_Musk |
| cd05110 | 875-1154 | PTKc_HER4 |
| cd05055 | 865-1153 | PTKc_PDGFR |
| cd05084 | 881-1142 | PTKc_Fes |
| cd05083 | 881-1150 | PTKc_Chk |
| cd05101 | 866-1153 | PTKc_FGFR2 |
| cd05073 | 864-1149 | PTKc_Hck |
| cd05100 | 879-1153 | PTKc_FGFR3 |
| cd05111 | 870-1149 | PTK_HER3 |
| cd05085 | 881-1145 | PTKc_Fer |
| cd05054 | 870-1147 | PTKc_VEGFR |
| cd00180 | 881-1074 | PKc |
| cd14203 | 879-1145 | PTKc_Src_Fyn_like |
| cd06606 | 876-1139 | STKc_MAPKKK |
| cd05063 | 864-1153 | PTKc_EphR_A2 |
| cd05097 | 870-1145 | PTKc_DDR_like |
| cd05094 | 869-1154 | PTKc_TrkC |
| cd05095 | 870-1145 | PTKc_DDR2 |
| cd05096 | 881-1145 | PTKc_DDR1 |
| cd05047 | 881-1146 | PTKc_Tie |
| cd05112 | 875-1146 | PTKc_Itk |
| cd05074 | 879-1153 | PTKc_Tyro3 |
| cd05090 | 873-1145 | PTKc_Ror1 |
| cd05093 | 869-1154 | PTKc_TrkB |
| cd05066 | 879-1153 | PTKc_EphR_A |
| cd05043 | 883-1148 | PTK_Ryk |
| cd14204 | 881-1154 | PTKc_Mer |
| cd05035 | 879-1153 | PTKc_TAM |
| cd05113 | 865-1146 | PTKc_Btk_Bmx |
| cd05036 | 875-1147 | PTKc_ALK_LTK |
| cd05061 | 878-1147 | PTKc_InsR |
| cd14059 | 881-1146 | STKc_MAP3K12_13 |
| cd05071 | 881-1149 | PTKc_Src |
| cd05069 | 881-1143 | PTKc_Yes |
| cd05089 | 881-1145 | PTKc_Tie1 |
| cd05065 | 881-1153 | PTKc_EphR_B |
| cd05103 | 870-1154 | PTKc_VEGFR2 |
| cd13335 | 281-426 | FERM_C_TYK2 |
| cd05075 | 879-1154 | PTKc_Axl |
| cd05088 | 881-1154 | PTKc_Tie2 |
| cd05091 | 873-1145 | PTKc_Ror2 |
| cd14207 | 870-1147 | PTKc_VEGFR1 |
| cd06627 | 881-1147 | STKc_Cdc7_like |
| cd05114 | 875-1147 | PTKc_Tec_Rlk |
| cd05070 | 875-1149 | PTKc_Fyn |
| cd13196 | 282-426 | FERM_C_JAK |
| cd05122 | 876-1139 | PKc_STE |
| cd05062 | 879-1146 | PTKc_IGF-1R |
| cd06625 | 876-1147 | STKc_MEKK3_like |
| cd05106 | 863-1153 | PTKc_CSF-1R |
| cd05064 | 879-1145 | PTKc_EphR_A10 |
| cd14061 | 881-1152 | STKc_MLK |
| cd14003 | 878-1076 | STKc_AMPK-like |
| cd00192 | 589-841 | PTKc |
| cd14014 | 878-1139 | STKc_PknB_like |
| cd05105 | 879-1153 | PTKc_PDGFR_alpha |
| cd05102 | 870-1154 | PTKc_VEGFR3 |
| cd07829 | 876-1076 | STKc_CDK_like |
| cd05104 | 865-1150 | PTKc_Kit |
| cd14060 | 882-1152 | STKc_MLTK |
| cd09921 | 426-527 | SH2_Jak_family |
| cd14146 | 881-1152 | STKc_MLK4 |
| cd14058 | 881-1149 | STKc_TAK1 |
| cd05118 | 878-1076 | STKc_CMGC |
| cd06652 | 881-1091 | STKc_MEKK2 |
| cd14008 | 881-1139 | STKc_LKB1_CaMKK |
| cd05107 | 879-1153 | PTKc_PDGFR_beta |
| cd06632 | 881-1147 | STKc_MEKK1_plant |
| cd06628 | 881-1146 | STKc_Byr2_like |
| cd14148 | 881-1152 | STKc_MLK2 |
| cd08215 | 876-1141 | STKc_Nek |
| cd07841 | 876-1141 | STKc_CDK7 |
| cd06651 | 876-1076 | STKc_MEKK3 |
| cd06653 | 881-1091 | STKc_MEKK3_like_u1 |
| cd14147 | 881-1152 | STKc_MLK3 |
| cd14145 | 881-1152 | STKc_MLK1 |
| cd05117 | 881-1076 | STKc_CAMK |
| cd05056 | 577-851 | PTKc_FAK |
| cd14066 | 881-1076 | STKc_IRAK |
| cd13978 | 881-1142 | STKc_RIP |
| cd05039 | 577-848 | PTKc_Csk_like |
| cd14065 | 881-1147 | PKc_LIMK_like |
| cd06623 | 875-1076 | PKc_MAPKK_plant_like |
| cd05084 | 586-845 | PTKc_Fes |
| cd00180 | 589-845 | PKc |
| cd05060 | 587-845 | PTKc_Syk_like |
| cd05085 | 586-845 | PTKc_Fer |
| cd14062 | 881-1150 | STKc_Raf |
| cd14206 | 878-1145 | PTKc_Aatyk3 |
| cd05038 | 589-848 | PTKc_Jak_rpt2 |
| cd14150 | 871-1152 | STKc_A-Raf |
| cd05040 | 611-842 | PTKc_Ack_like |
| cd13999 | 617-842 | STKc_MAP3K-like |
| cd05042 | 879-1145 | PTKc_Aatyk |
| cd07840 | 876-1076 | STKc_CDK9_like |
| cd06621 | 878-1074 | PKc_Pek1_like |
| cd07833 | 881-1146 | STKc_CDKL |
| cd14222 | 881-1152 | STKc_LIMK2 |
| cd06614 | 874-1147 | STKc_PAK |
| cd05087 | 878-1139 | PTKc_Aatyk1 |
| cd14078 | 881-1075 | STKc_MELK |
| cd05037 | 881-1146 | PTK_Jak_rpt1 |
| cd05041 | 587-845 | PTKc_Fes_like |
| cd06609 | 875-1089 | STKc_MST3_like |
| cd06612 | 881-1074 | STKc_MST1_2 |
| cd05059 | 578-845 | PTKc_Tec_like |
| cd13983 | 873-1076 | STKc_WNK |
| cd14079 | 881-1090 | STKc_AMPK_alpha |
| cd14137 | 875-1139 | STKc_GSK3 |
| cd14009 | 881-1143 | STKc_ATG1_ULK_like |
| cd06631 | 881-1086 | STKc_YSK4 |
| cd05044 | 589-846 | PTKc_c-ros |
| cd14154 | 881-1152 | STKc_LIMK |
| cd13333 | 315-426 | FERM_C_JAK2 |
| cd06629 | 881-1139 | STKc_Bck1_like |
| cd05032 | 578-841 | PTKc_InsR_like |
| cd14663 | 879-1141 | STKc_SnRK3 |
| cd06620 | 875-1145 | PKc_Byr1_like |
| cd05580 | 875-1093 | STKc_PKA_like |
| cd07838 | 881-1152 | STKc_CDK4_6_like |
| cd14155 | 881-1154 | PKc_TESK |
| cd06624 | 881-1148 | STKc_ASK |
| cd05068 | 617-850 | PTKc_Frk_like |
| cd14221 | 924-1153 | STKc_LIMK1 |
| cd14099 | 876-1076 | STKc_PLK |
| cd14069 | 878-1076 | STKc_Chk1 |
| cd14063 | 881-1154 | PK_KSR |
| cd05051 | 568-841 | PTKc_DDR |
| cd13997 | 869-1146 | PKc_Wee1_like |
| cd05082 | 613-839 | PTKc_Csk |
| cd05046 | 610-838 | PTK_CCK4 |
| cd05115 | 613-841 | PTKc_Zap-70 |
| cd05057 | 577-848 | PTKc_EGFR_like |
| cd06610 | 876-1147 | STKc_OSR1_SPAK |
| cd10381 | 426-527 | SH2_Jak_Tyk2 |
| cd05033 | 589-848 | PTKc_EphR |
| cd14066 | 589-848 | STKc_IRAK |
| cd05123 | 881-1076 | STKc_AGC |
| cd07835 | 876-1076 | STKc_CDK1_CdkB_like |
| cd06611 | 878-1091 | STKc_SLK_like |
| cd06644 | 878-1147 | STKc_STK10 |
| cd14158 | 879-1076 | STKc_IRAK4 |
| cd14664 | 881-1112 | STK_BAK1_like |
| cd14119 | 881-1145 | STKc_LKB1 |
| cd14027 | 881-1149 | STKc_RIP1 |
| cd14156 | 881-1152 | PKc_LIMK_like_unk |
| cd07845 | 868-1076 | STKc_CDK10 |
| cd13992 | 879-1149 | PK_GC |
| cd08220 | 876-1139 | STKc_Nek8 |
| cd14007 | 878-1076 | STKc_Aurora |
| cd07834 | 878-1141 | STKc_MAPK |
| cd07860 | 876-1076 | STKc_CDK2_3 |
| cd10380 | 426-525 | SH2_Jak3 |
| cd14151 | 881-1154 | STKc_B-Raf |
| cd05048 | 587-841 | PTKc_Ror |
| cd06640 | 866-1089 | STKc_MST4 |
| cd07861 | 877-1076 | STKc_CDK1_euk |
| cd08530 | 878-1146 | STKc_CNK2-like |
| cd06642 | 872-1089 | STKc_STK25 |
| cd14072 | 876-1076 | STKc_MARK |
| cd05114 | 635-850 | PTKc_Tec_Rlk |
| cd05073 | 615-844 | PTKc_Hck |
| cd13996 | 871-1147 | STKc_EIF2AK |
| cd13334 | 360-426 | FERM_C_JAK3 |
| cd13994 | 881-1076 | STKc_HAL4_like |
| cd05116 | 619-841 | PTKc_Syk |
| cd14058 | 644-853 | STKc_TAK1 |
| cd14152 | 881-1154 | STKc_KSR1 |
| cd14014 | 618-836 | STKc_PknB_like |
| cd13979 | 870-1141 | STKc_Mos |
| cd14077 | 873-1147 | STKc_Kin1_2 |
| cd05063 | 589-848 | PTKc_EphR_A2 |
| cd14084 | 879-1147 | STKc_Chk2 |
| cd07832 | 881-1075 | STKc_CCRK |
| cd06641 | 872-1074 | STKc_MST3 |
| cd05112 | 635-845 | PTKc_Itk |
| cd05086 | 878-1075 | PTKc_Aatyk2 |
| cd06605 | 875-1147 | PKc_MAPKK |
| cd14076 | 879-1084 | STKc_Kin4 |
| cd07843 | 876-1076 | STKc_CDC2L1 |
| cd14080 | 878-1076 | STKc_TSSK-like |
| cd07830 | 878-1139 | STKc_MAK_like |
| cd07836 | 876-1076 | STKc_Pho85 |
| cd14064 | 881-1152 | PKc_TNNI3K |
| cd05072 | 618-838 | PTKc_Lyn |
| cd14056 | 881-1141 | STKc_TGFbR_I |
| cd06917 | 876-1145 | STKc_NAK1_like |
| cd05052 | 635-848 | PTKc_Abl |
| cd14149 | 881-1152 | STKc_C-Raf |
| cd14203 | 589-838 | PTKc_Src_Fyn_like |
| cd05034 | 617-838 | PTKc_Src_like |
| cd05049 | 578-847 | PTKc_Trk |
| cd06613 | 878-1089 | STKc_MAP4K3_like |
| cd05066 | 614-848 | PTKc_EphR_A |
| cd06643 | 874-1147 | STKc_SLK |
| cd05097 | 635-841 | PTKc_DDR_like |
| cd14002 | 882-1076 | STKc_STK36 |
| cd05065 | 614-848 | PTKc_EphR_B |
| cd05067 | 618-844 | PTKc_Lck_Blk |
| cd05122 | 609-836 | PKc_STE |
| cd08218 | 877-1147 | STKc_Nek1 |
| cd14008 | 641-844 | STKc_LKB1_CaMKK |
| cd14042 | 922-1145 | PK_GC-A_B |
| cd14204 | 578-853 | PTKc_Mer |
| cd13985 | 879-1151 | STKc_GAK_like |
| cd05055 | 580-841 | PTKc_PDGFR |
| cd08219 | 878-1146 | STKc_Nek3 |
| cd05045 | 582-848 | PTKc_RET |
| cd05083 | 634-847 | PTKc_Chk |
| cd08222 | 878-1141 | STKc_Nek11 |
| cd05075 | 583-853 | PTKc_Axl |
| cd14053 | 884-1099 | STKc_ACVR2 |
| cd14162 | 881-1075 | STKc_TSSK4-like |
| cd08228 | 921-1074 | STKc_Nek6 |
| cd05078 | 881-1146 | PTK_Jak2_rpt1 |
| cd05092 | 578-846 | PTKc_TrkA |
| cd13975 | 876-1139 | PKc_Dusty |
| cd08529 | 925-1146 | STKc_FA2-like |
| cd05070 | 578-838 | PTKc_Fyn |
| cd05071 | 589-838 | PTKc_Src |
| cd05096 | 619-843 | PTKc_DDR1 |
| cd07862 | 878-1075 | STKc_CDK6 |
| cd05043 | 576-838 | PTK_Ryk |
| cd06626 | 877-1076 | STKc_MEKK4 |
| cd07871 | 877-1076 | STKc_PCTAIRE3 |
| cd14120 | 881-1076 | STKc_ULK1_2-like |
| cd07863 | 878-1153 | STKc_CDK4 |
| cd05035 | 583-848 | PTKc_TAM |
| cd14145 | 637-842 | STKc_MLK1 |
| cd07864 | 878-1076 | STKc_CDK12 |
| cd14073 | 878-1141 | STKc_NUAK |
| cd05093 | 613-853 | PTKc_TrkB |
| cd08225 | 878-1147 | STKc_Nek5 |
| cd05074 | 578-838 | PTKc_Tyro3 |
| cd07866 | 881-1076 | STKc_BUR1 |
| cd13978 | 619-838 | STKc_RIP |
| cd14161 | 881-1078 | STKc_NUAK2 |
| cd07846 | 881-1147 | STKc_CDKL2_3 |
| cd14081 | 879-1076 | STKc_BRSK1_2 |
| cd05069 | 589-841 | PTKc_Yes |
| cd14043 | 910-1149 | PK_GC-2D |
| cd14194 | 880-1084 | STKc_DAPK1 |
| cd05050 | 619-843 | PTKc_Musk |
| cd07873 | 877-1076 | STKc_PCTAIRE1 |
| cd14075 | 877-1076 | STKc_NIM1 |
| cd05113 | 635-845 | PTKc_Btk_Bmx |
| cd14121 | 903-1144 | STKc_ULK3 |
| cd14046 | 881-1036 | STKc_EIF2AK4_GCN2_rpt2 |
| cd13993 | 875-1145 | STKc_Pat1_like |
| cd05620 | 881-1075 | STKc_nPKC_delta |
| cd10379 | 426-523 | SH2_Jak2 |
| cd14006 | 881-1076 | STKc_MLCK-like |
| cd14105 | 880-1078 | STKc_DAPK |
| cd05612 | 875-1124 | STKc_PRKX_like |
| cd05148 | 580-841 | PTKc_Srm_Brk |
| cd07831 | 876-1076 | STKc_MOK |
| cd14196 | 880-1084 | STKc_DAPK2 |
| cd06608 | 882-1089 | STKc_myosinIII_N_like |
| cd14054 | 881-1084 | STKc_BMPR2_AMHR2 |
| cd14000 | 881-1139 | STKc_LRRK |
| cd05572 | 881-1094 | STKc_cGK |
| cd14012 | 911-1149 | PK_eIF2AK_GCN2_rpt1 |
| cd05581 | 878-1076 | STKc_PDK1 |
| cd14098 | 878-1093 | STKc_Rad53_Cds1 |
| cd14147 | 625-848 | STKc_MLK3 |
| cd05036 | 589-847 | PTKc_ALK_LTK |
| cd14201 | 879-1075 | STKc_ULK2 |
| cd14202 | 879-1076 | STKc_ULK1 |
| cd13998 | 882-1143 | STKc_TGFbR-like |
| cd05579 | 884-1090 | STKc_MAST_like |
| cd14095 | 879-1075 | STKc_DCKL |
| cd08224 | 879-1139 | STKc_Nek6_7 |
| cd14070 | 879-1076 | STKc_HUNK |
| cd05108 | 577-848 | PTKc_EGFR |
| cd14165 | 879-1085 | STKc_TSSK1_2-like |
| cd06633 | 878-1074 | STKc_TAO3 |
| cd14208 | 875-1146 | PTK_Jak3_rpt1 |
| cd14146 | 637-848 | STKc_MLK4 |
| cd13987 | 881-1090 | STKc_SBK1 |
| cd06639 | 878-1074 | STKc_myosinIIIB_N |
| cd14059 | 589-846 | STKc_MAP3K12_13 |
| cd07847 | 877-1147 | STKc_CDKL1_4 |
| cd07852 | 871-1139 | STKc_MAPK15-like |
| cd05098 | 566-848 | PTKc_FGFR1 |
| cd14186 | 881-1076 | STKc_PLK4 |
| cd05094 | 578-853 | PTKc_TrkC |
| cd08229 | 920-1139 | STKc_Nek7 |
| cd06648 | 866-1075 | STKc_PAK_II |
| cd14192 | 881-1076 | STKc_MLCK3 |
| cd14045 | 922-1145 | PK_GC_unk |
| cd05095 | 580-843 | PTKc_DDR2 |
| cd05099 | 580-848 | PTKc_FGFR4 |
| cd13988 | 881-1076 | STKc_TBK1 |
| cd05053 | 582-848 | PTKc_FGFR |
| cd14047 | 876-1080 | STKc_EIF2AK2_PKR |
| cd06630 | 901-1076 | STKc_MEKK1 |
| cd05064 | 633-848 | PTKc_EphR_A10 |
| cd14071 | 874-1074 | STKc_SIK |
| cd07865 | 876-1076 | STKc_CDK9 |
| cd14068 | 881-1143 | STKc_LRRK2 |
| cd14074 | 881-1074 | STKc_SNRK |
| cd07837 | 876-1074 | STKc_CdkB_plant |
| cd05582 | 881-1139 | STKc_RSK_N |
| cd05110 | 577-848 | PTKc_HER4 |
| cd14060 | 639-848 | STKc_MLTK |
| cd05079 | 577-848 | PTKc_Jak1_rpt2 |
| cd14144 | 879-1139 | STKc_BMPR1 |
| cd06658 | 866-1075 | STKc_PAK5 |
| cd06606 | 582-836 | STKc_MAPKKK |
| cd06659 | 866-1075 | STKc_PAK6 |
| cd05061 | 589-850 | PTKc_InsR |
| cd14665 | 878-1075 | STKc_SnRK2-3 |
| cd14009 | 589-835 | STKc_ATG1_ULK_like |
| cd05595 | 881-1075 | STKc_PKB_beta |
| cd14103 | 881-1075 | STKc_MLCK |
| cd07849 | 881-1076 | STKc_ERK1_2_like |
| cd07848 | 881-1139 | STKc_CDKL5 |
| cd13986 | 877-1153 | STKc_16 |
| cd14190 | 881-1076 | STKc_MLCK2 |
| cd14033 | 873-1076 | STKc_WNK4 |
| cd14038 | 881-1076 | STKc_IKK_beta |
| cd14061 | 613-848 | STKc_MLK |
| cd05619 | 881-1075 | STKc_nPKC_theta |
| cd14209 | 877-1074 | STKc_PKA |
| cd14187 | 865-1075 | STKc_PLK1 |
| cd14185 | 879-1075 | STKc_DCKL3 |
| cd06607 | 878-1074 | STKc_TAO |
| cd14159 | 881-1152 | STKc_IRAK1 |
| cd07877 | 881-1076 | STKc_p38alpha |
| cd07839 | 877-1074 | STKc_CDK5 |
| cd06637 | 881-1089 | STKc_TNIK |
| cd07880 | 864-1076 | STKc_p38gamma |
| cd14091 | 880-1076 | STKc_RSK_C |
| cd07872 | 877-1074 | STKc_PCTAIRE2 |
| cd07842 | 882-1077 | STKc_CDK8_like |
| cd14026 | 878-1154 | STKc_RIP2 |
| cd07858 | 901-1076 | STKc_TEY_MAPK |
| cd08528 | 881-1139 | STKc_Nek10 |
| cd14199 | 864-1072 | STKc_CaMKK2 |
| cd08223 | 878-1146 | STKc_Nek4 |
| cd08217 | 925-1147 | STKc_Nek2 |
| cd14114 | 880-1086 | STKc_Twitchin_like |
| cd05611 | 878-1076 | STKc_Rim15_like |
| cd14083 | 881-1082 | STKc_CaMKI |
| cd07844 | 876-1076 | STKc_PCTAIRE_like |
| cd14195 | 880-1084 | STKc_DAPK3 |
| cd06635 | 872-1074 | STKc_TAO1 |
| cd06638 | 878-1074 | STKc_myosinIIIA_N |
| cd08221 | 878-1147 | STKc_Nek9 |
| cd05100 | 566-848 | PTKc_FGFR3 |
| cd14205 | 641-849 | PTKc_Jak2_rpt2 |
| cd14148 | 613-845 | STKc_MLK2 |
| cd07878 | 875-1104 | STKc_p38beta |
| cd14063 | 634-848 | PK_KSR |
| cd05090 | 587-841 | PTKc_Ror1 |
| cd06634 | 872-1074 | STKc_TAO2 |
| cd06647 | 872-1075 | STKc_PAK_I |
| cd14662 | 878-1075 | STKc_SnRK2 |
| cd14116 | 879-1075 | STKc_Aurora-A |
| cd14167 | 881-1075 | STKc_CaMKI_alpha |
| cd06636 | 881-1089 | STKc_MAP4K4_6_N |
| cd14052 | 873-1073 | PTKc_Wee1_fungi |
| cd14193 | 881-1076 | STKc_MLCK4 |
| cd05593 | 868-1075 | STKc_PKB_gamma |
| cd14010 | 901-1076 | STKc_ULK4 |
| cd14200 | 864-1078 | STKc_CaMKK1 |
| cd14062 | 617-845 | STKc_Raf |
| cd14001 | 874-1151 | PKc_TOPK |
| cd05080 | 577-842 | PTKc_Tyk2_rpt2 |
| cd14150 | 620-850 | STKc_A-Raf |
| cd06646 | 878-1089 | STKc_MAP4K5 |
| cd05599 | 870-1075 | STKc_NDR_like |
| cd05077 | 928-1146 | PTK_Jak1_rpt1 |
| cd13989 | 881-1076 | STKc_IKK |
| cd06649 | 875-1074 | PKc_MEK2 |
| cd05101 | 566-848 | PTKc_FGFR2 |
| cd05109 | 577-848 | PTKc_HER2 |
| cd06611 | 647-844 | STKc_SLK_like |
| cd06917 | 587-835 | STKc_NAK1_like |
| cd14118 | 880-1091 | STKc_CAMKK |
| cd14025 | 879-1145 | STKc_RIP4_like |
| cd06650 | 875-1074 | PKc_MEK1 |
| cd14142 | 873-1139 | STKc_ACVR1_ALK1 |
| cd14166 | 881-1075 | STKc_CaMKI_gamma |
| cd05047 | 628-850 | PTKc_Tie |
| cd06615 | 875-1076 | PKc_MEK |
| cd14155 | 639-851 | PKc_TESK |
| cd14050 | 876-1079 | PKc_Myt1 |
| cd05062 | 578-847 | PTKc_IGF-1R |
| cd05105 | 697-848 | PTKc_PDGFR_alpha |
| cd06657 | 866-1075 | STKc_PAK4 |
| cd14065 | 605-838 | PKc_LIMK_like |
| cd14132 | 899-1075 | STKc_CK2_alpha |
| cd14049 | 881-1147 | STKc_EIF2AK1_HRI |
| cd05589 | 881-1075 | STKc_PKN |
| cd13982 | 897-1079 | STKc_IRE1 |
| cd05117 | 611-836 | STKc_CAMK |
| cd05091 | 587-841 | PTKc_Ror2 |
| cd07857 | 878-1147 | STKc_MPK1 |
| cd14178 | 880-1075 | STKc_RSK3_C |
| cd14175 | 880-1078 | STKc_RSK1_C |
| cd13992 | 642-848 | PK_GC |
| cd14183 | 867-1075 | STKc_DCKL1 |
| cd14176 | 879-1076 | STKc_RSK2_C |
| cd14121 | 587-835 | STKc_ULK3 |
| cd14039 | 881-1073 | STKc_IKK_alpha |
| cd14055 | 881-1152 | STKc_TGFbR2_like |
| cd05573 | 878-1075 | STKc_ROCK_NDR_like |
| cd07854 | 924-1076 | STKc_MAPK4_6 |
| cd06632 | 585-836 | STKc_MEKK1_plant |
| cd05594 | 856-1075 | STKc_PKB_alpha |
| cd14149 | 620-855 | STKc_C-Raf |
| cd05076 | 899-1146 | PTK_Tyk2_rpt1 |
| cd05592 | 881-1075 | STKc_nPKC_theta_like |
| cd06656 | 872-1075 | STKc_PAK3 |
| cd14154 | 635-838 | STKc_LIMK |
| cd05111 | 577-853 | PTK_HER3 |
| cd14117 | 879-1147 | STKc_Aurora-B_like |
| cd14184 | 881-1075 | STKc_DCKL2 |
| cd14016 | 878-1026 | STKc_CK1 |
| cd14048 | 871-1147 | STKc_EIF2AK3_PERK |
| cd07856 | 901-1075 | STKc_Sty1_Hog1 |
| cd05058 | 589-845 | PTKc_Met_Ron |
| cd14093 | 881-1078 | STKc_PhKG |
| cd14082 | 881-1072 | STKc_PKD |
| cd05578 | 878-1076 | STKc_Yank1 |
| cd07855 | 876-1075 | STKc_ERK5 |
| cd14189 | 879-1075 | STKc_PLK3 |
| cd14169 | 881-1090 | STKc_CaMKI_beta |
| cd14177 | 880-1075 | STKc_RSK4_C |
| cd14097 | 879-1075 | STKc_STK33 |
| cd13987 | 646-787 | STKc_SBK1 |
| cd14037 | 878-1151 | STKc_NAK_like |
| cd05570 | 881-1076 | STKc_PKC |
| cd14086 | 880-1075 | STKc_CaMKII |
| cd14044 | 888-1145 | PK_GC-C |
| cd07859 | 881-1076 | STKc_TDY_MAPK |
| cd14003 | 642-844 | STKc_AMPK-like |
| cd14210 | 881-1076 | PKc_DYRK |
| cd14198 | 879-1086 | STKc_DRAK2 |
| cd06645 | 878-1089 | STKc_MAP4K3 |
| cd07879 | 864-1076 | STKc_p38delta |
| cd05571 | 881-1075 | STKc_PKB |
| cd14220 | 879-1139 | STKc_BMPR1a |
| cd14106 | 879-1086 | STKc_DRAK |
| cd05608 | 879-1075 | STKc_GRK1 |
| cd14191 | 881-1076 | STKc_MLCK1 |
| cd06648 | 636-839 | STKc_PAK_II |
| cd14134 | 873-1076 | PKc_CLK |
| cd13968 | 881-1023 | PKc_like |
| cd14168 | 881-1090 | STKc_CaMKI_delta |
| cd14000 | 635-836 | STKc_LRRK |
| cd06654 | 872-1075 | STKc_PAK1 |
| cd14004 | 878-1075 | STKc_PASK |
| cd14164 | 879-1143 | STKc_TSSK6-like |
| cd06610 | 615-836 | STKc_OSR1_SPAK |
| cd14207 | 697-848 | PTKc_VEGFR1 |
| cd06617 | 875-1076 | PKc_MKK3_6 |
| cd06619 | 881-1147 | PKc_MKK5 |
| cd07870 | 878-1075 | STKc_PFTAIRE2 |
| cd07869 | 876-1075 | STKc_PFTAIRE1 |
| cd14153 | 881-1154 | PK_KSR2 |
| cd06627 | 586-836 | STKc_Cdc7_like |
| cd06643 | 612-786 | STKc_SLK |
| cd07851 | 878-1076 | STKc_p38 |
| cd05616 | 881-1075 | STKc_cPKC_beta |
| cd14143 | 881-1139 | STKc_TGFbR1_ACVR1b_ACVR1c |
| cd05607 | 873-1075 | STKc_GRK7 |
| cd06617 | 582-857 | PKc_MKK3_6 |
| cd14219 | 875-1141 | STKc_BMPR1b |
| cd06644 | 622-786 | STKc_STK10 |
| cd14057 | 902-1146 | PK_ILK |
| cd14031 | 873-1076 | STKc_WNK3 |
| cd14036 | 875-1152 | STKc_GAK |
| cd05590 | 879-1075 | STKc_nPKC_eta |
| cd05630 | 875-1110 | STKc_GRK6 |
| cd05103 | 697-852 | PTKc_VEGFR2 |
| cd08226 | 888-1146 | PK_STRAD_beta |
| cd06631 | 585-836 | STKc_YSK4 |
| cd14136 | 878-1076 | STKc_SRPK |
| cd14113 | 874-1076 | STKc_Trio_C |
| cd06623 | 582-836 | PKc_MAPKK_plant_like |
| cd06655 | 872-1075 | STKc_PAK2 |
| cd14174 | 881-1076 | STKc_Mnk1 |
| cd14030 | 873-1076 | STKc_WNK1 |
| cd05584 | 881-1076 | STKc_p70S6K |
| cd05088 | 628-872 | PTKc_Tie2 |
| cd06616 | 870-1076 | PKc_MKK4 |
| cd05577 | 881-1075 | STKc_GRK |
| cd14032 | 873-1076 | STKc_WNK2_like |
| cd14025 | 637-841 | STKc_RIP4_like |
| cd14064 | 635-845 | PKc_TNNI3K |
| cd05631 | 875-1075 | STKc_GRK4 |
| cd14188 | 922-1075 | STKc_PLK2 |
| cd14012 | 629-836 | PK_eIF2AK_GCN2_rpt1 |
| cd07853 | 986-1075 | STKc_NLK |
| cd05106 | 642-848 | PTKc_CSF-1R |
| cd14151 | 586-848 | STKc_B-Raf |
| cd08215 | 618-843 | STKc_Nek |
| cd14163 | 879-1075 | STKc_TSSK3-like |
| cd06608 | 586-843 | STKc_myosinIII_N_like |
| cd05102 | 697-852 | PTKc_VEGFR3 |
| cd14197 | 879-1076 | STKc_DRAK1 |
| cd14663 | 586-844 | STKc_SnRK3 |
| cd14111 | 882-1077 | STKc_SPEG_rpt2 |
| cd14027 | 619-841 | STKc_RIP1 |
| cd08529 | 639-843 | STKc_FA2-like |
| cd06614 | 615-836 | STKc_PAK |
| cd14156 | 640-850 | PKc_LIMK_like_unk |
| cd14067 | 635-836 | STKc_LRRK1 |
| cd14019 | 878-1076 | STKc_Cdc7 |
| cd06622 | 875-1147 | PKc_PBS2_like |
| cd13990 | 881-1139 | STKc_TLK |
| cd14085 | 879-1075 | STKc_CaMKIV |
| cd14097 | 609-808 | STKc_STK33 |
| cd08227 | 889-1074 | PK_STRAD_alpha |
| cd05603 | 881-1075 | STKc_SGK2 |
| cd08216 | 901-1095 | PK_STRAD |
| cd14094 | 881-1078 | STKc_CASK |
| cd05602 | 867-1075 | STKc_SGK1 |
| cd05609 | 954-1093 | STKc_MAST |
| cd14072 | 611-844 | STKc_MARK |
| cd14057 | 620-848 | PK_ILK |
| cd14080 | 586-836 | STKc_TSSK-like |
| cd06629 | 584-836 | STKc_Bck1_like |
| cd05627 | 875-1075 | STKc_NDR2 |
| cd05615 | 881-1075 | STKc_cPKC_alpha |
| cd14222 | 635-838 | STKc_LIMK2 |
| cd14160 | 881-1152 | PK_IRAK3 |
| cd05581 | 581-836 | STKc_PDK1 |
| cd14011 | 697-836 | PK_SCY1_like |
| cd05081 | 635-848 | PTKc_Jak3_rpt2 |
| cd14133 | 881-1076 | PKc_DYRK_like |
| cd06642 | 587-843 | STKc_STK25 |
| cd06621 | 618-836 | PKc_Pek1_like |
| cd05626 | 877-1127 | STKc_LATS2 |
| cd05628 | 875-1075 | STKc_NDR1 |
| cd14119 | 640-843 | STKc_LKB1 |
| cd14202 | 641-816 | STKc_ULK1 |
| cd05587 | 881-1075 | STKc_cPKC |
| cd14099 | 581-844 | STKc_PLK |
| cd05580 | 640-852 | STKc_PKA_like |
| cd14152 | 616-852 | STKc_KSR1 |
| cd14096 | 876-1075 | STKc_RCK1-like |
| cd06613 | 611-836 | STKc_MAP4K3_like |
| cd05571 | 666-874 | STKc_PKB |
| cd05107 | 697-838 | PTKc_PDGFR_beta |
| cd13995 | 879-1076 | STKc_MAP3K8 |
| cd14092 | 876-1075 | STKc_MSK_C |
| cd05613 | 881-1126 | STKc_MSK1_N |
| cd05632 | 872-1075 | STKc_GRK5 |
| cd07876 | 902-1075 | STKc_JNK2 |
| cd14078 | 642-835 | STKc_MELK |
| cd05123 | 617-838 | STKc_AGC |
| cd05598 | 876-1075 | STKc_LATS |
| cd05089 | 628-850 | PTKc_Tie1 |
| cd14067 | 885-1139 | STKc_LRRK1 |
| cd14195 | 608-835 | STKc_DAPK3 |
| smart00252 | 437-532 | SH2 |
| cd14131 | 919-1145 | PKc_Mps1 |
| cd14104 | 880-1076 | STKc_Titin |
| cd14140 | 923-1089 | STKc_ACVR2b |
| cd13997 | 626-842 | PKc_Wee1_like |
| cd14182 | 870-1092 | STKc_PhKG1 |
| cd05104 | 697-851 | PTKc_Kit |
| cd05604 | 881-1075 | STKc_SGK3 |
| cd06618 | 875-1076 | PKc_MKK7 |
| cd05625 | 877-1129 | STKc_LATS1 |
| cd14185 | 641-835 | STKc_DCKL3 |
| cd14212 | 881-1074 | PKc_YAK1 |
| cd05574 | 875-1026 | STKc_phototropin_like |
| cd14173 | 881-1081 | STKc_Mnk2 |
| cd08228 | 589-836 | STKc_Nek6 |
| cd14179 | 881-1076 | STKc_MSK1_C |
| cd06628 | 584-836 | STKc_Byr2_like |
| cd14089 | 881-1075 | STKc_MAPKAPK |
| cd14109 | 913-1076 | PK_Unc-89_rpt1 |
| cd05054 | 647-848 | PTKc_VEGFR |
| cd05583 | 881-1139 | STKc_MSK_N |
| cd14221 | 635-838 | STKc_LIMK1 |
| cd14224 | 881-1112 | PKc_DYRK2_3 |
| cd14004 | 640-836 | STKc_PASK |
| cd14042 | 574-847 | PK_GC-A_B |
| cd14001 | 587-836 | PKc_TOPK |
| cd14201 | 580-840 | STKc_ULK2 |
| cd05600 | 878-1076 | STKc_Sid2p_like |
| cd14090 | 881-1075 | STKc_Mnk |
| cd07867 | 881-1076 | STKc_CDC2L6 |
| cd14180 | 881-1076 | STKc_MSK2_C |
| cd14141 | 925-1136 | STKc_ACVR2a |
| cd05595 | 666-874 | STKc_PKB_beta |
| cd06640 | 587-843 | STKc_MST4 |
| cd06605 | 588-842 | PKc_MAPKK |
| cd07868 | 924-1076 | STKc_CDK8 |
| cd05614 | 881-1139 | STKc_MSK2_N |
| cd06641 | 587-843 | STKc_MST3 |
| cd14110 | 924-1070 | STKc_obscurin_rpt2 |
| cd14011 | 917-1076 | PK_SCY1_like |
| cd05589 | 589-841 | STKc_PKN |
| cd13984 | 922-1146 | PK_NRBP1_like |
| cd06626 | 585-836 | STKc_MEKK4 |
| cd14120 | 641-835 | STKc_ULK1_2-like |
| cd14026 | 615-838 | STKc_RIP2 |
| cd14181 | 901-1092 | STKc_PhKG2 |
| cd14095 | 608-746 | STKc_DCKL |
| cd14196 | 608-798 | STKc_DAPK2 |
| cd05601 | 881-1075 | STKc_CRIK |
| cd14108 | 923-1076 | STKc_SPEG_rpt1 |
| cd14007 | 642-836 | STKc_Aurora |
| cd14209 | 642-786 | STKc_PKA |
| cd14107 | 954-1086 | STKc_obscurin_rpt1 |
| cd14229 | 881-1075 | STKc_HIPK3 |
| cd06659 | 618-835 | STKc_PAK6 |
| cd14194 | 640-835 | STKc_DAPK1 |
| cd06637 | 587-843 | STKc_TNIK |
| cd08225 | 641-843 | STKc_Nek5 |
| cd14179 | 611-835 | STKc_MSK1_C |
| cd14002 | 587-793 | STKc_STK36 |
| cd05605 | 983-1076 | STKc_GRK4_like |
| cd14184 | 640-824 | STKc_DCKL2 |
| cd06609 | 587-836 | STKc_MST3_like |
| cd14116 | 586-842 | STKc_Aurora-A |
| cd14172 | 881-1075 | STKc_MAPKAPK3 |
| cd14071 | 616-835 | STKc_SIK |
| cd14206 | 635-836 | PTKc_Aatyk3 |
| cd06620 | 581-836 | PKc_Byr1_like |
| cd14105 | 640-780 | STKc_DAPK |
| cd14153 | 586-851 | PK_KSR2 |
| cd05611 | 617-844 | STKc_Rim15_like |
| cd14135 | 878-1076 | STKc_PRP4 |
| cd14664 | 589-786 | STK_BAK1_like |
| cd13994 | 643-836 | STKc_HAL4_like |
| cd08220 | 641-842 | STKc_Nek8 |
| cd08229 | 589-836 | STKc_Nek7 |
| cd06658 | 610-835 | STKc_PAK5 |
| cd06636 | 587-796 | STKc_MAP4K4_6_N |
| cd05612 | 640-801 | STKc_PRKX_like |
| cd14166 | 579-835 | STKc_CaMKI_gamma |
| cd14006 | 639-782 | STKc_MLCK-like |
| cd05619 | 582-875 | STKc_nPKC_theta |
| cd14069 | 643-783 | STKc_Chk1 |
| cd14052 | 664-793 | PTKc_Wee1_fungi |
| cd05582 | 608-877 | STKc_RSK_N |
| cd05118 | 618-836 | STKc_CMGC |
| cd07833 | 605-842 | STKc_CDKL |
| cd06657 | 619-835 | STKc_PAK4 |
| cd13986 | 622-848 | STKc_16 |
| cd08218 | 697-843 | STKc_Nek1 |
| cd14043 | 619-847 | PK_GC-2D |
| cd06612 | 640-836 | STKc_MST1_2 |
| cd07836 | 584-786 | STKc_Pho85 |
| cd05578 | 641-835 | STKc_Yank1 |
| cd06630 | 584-836 | STKc_MEKK1 |
| cd14106 | 637-780 | STKc_DRAK |
| cd14096 | 607-835 | STKc_RCK1-like |
| cd06645 | 587-836 | STKc_MAP4K3 |
| cd08224 | 615-836 | STKc_Nek6_7 |
| cd13993 | 643-835 | STKc_Pat1_like |
| cd05620 | 666-875 | STKc_nPKC_delta |
| cd06624 | 589-836 | STKc_ASK |
| cd14084 | 641-843 | STKc_Chk2 |
| cd14165 | 612-835 | STKc_TSSK1_2-like |
| cd05086 | 635-796 | PTKc_Aatyk2 |
| cd14159 | 634-821 | STKc_IRAK1 |
| cd14038 | 611-794 | STKc_IKK_beta |
| cd07830 | 637-836 | STKc_MAK_like |
| cd14075 | 616-844 | STKc_NIM1 |
| cd06656 | 580-835 | STKc_PAK3 |
| cd06654 | 580-835 | STKc_PAK1 |
| cd14187 | 580-844 | STKc_PLK1 |
| cd06655 | 580-835 | STKc_PAK2 |
| cd05087 | 633-836 | PTKc_Aatyk1 |
| cd05042 | 635-793 | PTKc_Aatyk |
| cd14077 | 636-835 | STKc_Kin1_2 |
| cd14068 | 641-836 | STKc_LRRK2 |
| cd06646 | 582-836 | STKc_MAP4K5 |
| cd14094 | 637-835 | STKc_CASK |
| cd06639 | 587-836 | STKc_myosinIIIB_N |
| cd08528 | 587-836 | STKc_Nek10 |
| cd06647 | 580-835 | STKc_PAK_I |
| cd13975 | 586-841 | PKc_Dusty |
| cd07829 | 629-838 | STKc_CDK_like |
| cd14137 | 641-838 | STKc_GSK3 |
| cd08221 | 660-836 | STKc_Nek9 |
| cd07838 | 584-836 | STKc_CDK4_6_like |
| cd14131 | 612-836 | PKc_Mps1 |
| cd08530 | 641-836 | STKc_CNK2-like |
| cd14200 | 622-835 | STKc_CaMKK1 |
| cd14045 | 642-848 | PK_GC_unk |
| cd06615 | 644-802 | PKc_MEK |
| cd14173 | 611-784 | STKc_Mnk2 |
| cd05593 | 666-874 | STKc_PKB_gamma |
| cd14092 | 611-784 | STKc_MSK_C |
| cd05592 | 666-875 | STKc_nPKC_theta_like |
| cd14164 | 611-836 | STKc_TSSK6-like |
| cd13982 | 609-836 | STKc_IRE1 |
| cd14098 | 614-836 | STKc_Rad53_Cds1 |
| cd06653 | 585-786 | STKc_MEKK3_like_u1 |
| cd05614 | 665-874 | STKc_MSK2_N |
| cd06622 | 587-877 | PKc_PBS2_like |
| cd13984 | 644-836 | PK_NRBP1_like |
| cd08222 | 639-844 | STKc_Nek11 |
| cd14199 | 636-835 | STKc_CaMKK2 |
| cd05590 | 646-786 | STKc_nPKC_eta |
| cd14073 | 587-845 | STKc_NUAK |
| cd14174 | 611-794 | STKc_Mnk1 |
| cd06607 | 640-786 | STKc_TAO |
| cd14158 | 617-848 | STKc_IRAK4 |
| cd14183 | 640-835 | STKc_DCKL1 |
| cd06650 | 644-836 | PKc_MEK1 |
| cd07841 | 584-787 | STKc_CDK7 |
| cd06616 | 582-793 | PKc_MKK4 |
| cd13989 | 609-786 | STKc_IKK |
| cd14188 | 585-843 | STKc_PLK2 |
| cd05579 | 642-841 | STKc_MAST_like |
| cd14219 | 665-850 | STKc_BMPR1b |
| cd05604 | 617-788 | STKc_SGK3 |
| cd14082 | 587-784 | STKc_PKD |
| cd07843 | 640-796 | STKc_CDC2L1 |
| cd14085 | 586-780 | STKc_CaMKIV |
| cd06619 | 649-857 | PKc_MKK5 |
| cd14109 | 629-835 | PK_Unc-89_rpt1 |
| cd14050 | 690-842 | PKc_Myt1 |
| cd05577 | 695-841 | STKc_GRK |
| cd14044 | 602-848 | PK_GC-C |
| cd13985 | 640-847 | STKc_GAK_like |
| cd14161 | 587-794 | STKc_NUAK2 |
| cd07835 | 629-835 | STKc_CDK1_CdkB_like |
| cd14180 | 637-797 | STKc_MSK2_C |
| cd14189 | 581-843 | STKc_PLK3 |
| cd14089 | 621-741 | STKc_MAPKAPK |
| cd13979 | 586-786 | STKc_Mos |
| cd14074 | 618-835 | STKc_SNRK |
| cd14083 | 640-780 | STKc_CaMKI |
| cd05603 | 589-788 | STKc_SGK2 |
| cd14117 | 582-842 | STKc_Aurora-B_like |
| cd06633 | 642-786 | STKc_TAO3 |
| cd07852 | 647-836 | STKc_MAPK15-like |
| cd14108 | 639-806 | STKc_SPEG_rpt1 |
| cd13990 | 640-836 | STKc_TLK |
| cd14144 | 665-835 | STKc_BMPR1 |
| cd07845 | 641-786 | STKc_CDK10 |
| cd14197 | 650-780 | STKc_DRAK1 |
| cd14070 | 611-844 | STKc_HUNK |
| cd06625 | 640-836 | STKc_MEKK3_like |
| cd07846 | 641-837 | STKc_CDKL2_3 |
| cd13968 | 605-722 | PKc_like |
| cd07840 | 643-801 | STKc_CDK9_like |
| cd14039 | 589-787 | STKc_IKK_alpha |
| cd06634 | 642-878 | STKc_TAO2 |
| cd14076 | 586-796 | STKc_Kin4 |
| cd07868 | 572-786 | STKc_CDK8 |
| cd05574 | 758-856 | STKc_phototropin_like |
| cd06618 | 580-842 | PKc_MKK7 |
| cd06649 | 641-813 | PKc_MEK2 |
| cd14190 | 620-780 | STKc_MLCK2 |
| pfam07714 | 875-1147 | Pkinase_Tyr |
| pfam07714 | 583-845 | Pkinase_Tyr |
| smart00295 | 37-286 | B41 |
| smart00219 | 875-1149 | TyrKc |
| smart00221 | 875-1149 | STYKc |
| smart00220 | 876-1147 | S_TKc |
| pfam00069 | 875-1147 | Pkinase |
| smart00219 | 589-845 | TyrKc |
| smart00221 | 589-845 | STYKc |
| COG0515 | 878-1154 | SPS1 |
| smart00220 | 586-844 | S_TKc |
| pfam00069 | 586-844 | Pkinase |
| PTZ00024 | 872-1076 | PTZ00024 |
| PLN00034 | 875-1073 | PLN00034 |
| PTZ00036 | 881-1141 | PTZ00036 |
| COG0515 | 586-946 | SPS1 |
| PHA03209 | 925-1109 | PHA03209 |
| PTZ00267 | 923-1147 | PTZ00267 |
| PLN00009 | 876-1076 | PLN00009 |
| PTZ00263 | 881-1092 | PTZ00263 |
| PTZ00266 | 878-1115 | PTZ00266 |
| PTZ00426 | 878-1092 | PTZ00426 |
| PRK13184 | 878-1076 | pknD |
| PTZ00283 | 863-1076 | PTZ00283 |
| PHA03210 | 874-1092 | PHA03210 |
| PHA02988 | 902-1150 | PHA02988 |
| PHA03390 | 950-1076 | pk1 |
| PHA03212 | 925-1080 | PHA03212 |
| PHA03207 | 844-1075 | PHA03207 |
| PTZ00263 | 639-872 | PTZ00263 |
| PTZ00036 | 586-786 | PTZ00036 |
| PTZ00426 | 636-786 | PTZ00426 |
| PLN00034 | 621-836 | PLN00034 |
| TIGR03903 | 901-1076 | TOMM_kin_cyc |
Ontology Information
| HPRD ID | 2777 |
|---|---|
| Molecular Class | Tyrosine kinase |
| Molecular Function | Transcription factor activity (GO:0003700) |
| Biological Process | Regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism (GO:0019219) |
Drug Information
| Uniprot ID | DrugBank ID | Name | Type |
|---|---|---|---|
| P23458 | DB08877 | Ruxolitinib | SmallMoleculeDrug |
| P23458 | DB08895 | Tofacitinib | SmallMoleculeDrug |