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• Evidence
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Evidence Information

Pubmed ID	Year	Sample Information	Techniques	Mechanism	Fold Change	Remark
20089989	2010	Cell line : - Source : VU University Medical Center, Amsterdam, The Netherlands. Sample Type : CRC tumor and normal tissue No. of Sample : - Stage : -	Biochemical isolation to nano-LC-MS/MS analysis	Up-regulation	-	This genes are differenitially expressed between colorectal adenoma and Colorectal cancer tissue.

Gene Details

Chromosome: 3; NC_000003.11 (49158547..49170599, complement)
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Gene Type	protein coding
Gene Family	Laminins
Description	Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Laminins, composed of 3 non identical chains: laminin alpha, beta and gamma (formerly A, B1, and B2, respectively), form a cruciform structure consisting of 3 short arms, each formed by a different chain, and a long arm composed of all 3 chains. Each laminin chain is a multidomain protein encoded by a distinct gene. Several isoforms of each chain have been described. Different alpha, beta and gamma chain isomers combine to give rise to different heterotrimeric laminin isoforms which are designated by Arabic numerals in the order of their discovery, i.e. alpha1beta1gamma1 heterotrimer is laminin 1. The biological functions of the different chains and trimer molecules are largely unknown, but some of the chains have been shown to differ with respect to their tissue distribution, presumably reflecting diverse functions in vivo. This gene encodes the beta chain isoform laminin, beta 2. The beta 2 chain contains the 7 structural domains typical of beta chains of laminin, including the short alpha region. However, unlike beta 1 chain, beta 2 has a more restricted tissue distribution. It is enriched in the basement membrane of muscles at the neuromuscular junctions, kidney glomerulus and vascular smooth muscle. Transgenic mice in which the beta 2 chain gene was inactivated by homologous recombination, showed defects in the maturation of neuromuscular junctions and impairment of glomerular filtration. Alternative splicing involving a non consensus 5' splice site (gc) in the 5' UTR of this gene has been reported. It was suggested that inefficient splicing of this first intron, which does not change the protein sequence, results in a greater abundance of the unspliced form of the transcript than the spliced form. The full-length nature of the spliced transcript is not known. [provided by RefSeq, Aug 2011]
Chromosome	3
Location	3p21
Start	49121114
End	49133166
Strand	-
Gene Sequence	>gi|568815595:c49133166-49121114 Homo sapiens chromosome 3, GRCh38.p2 Primary Assembly GAAGGCAGTTTCCGGAGGGAAGGGGTAGGGTTGGGGTGGGGGCGCTCTCCGCCCGGTGTTGCGCTCCTTC CCAGAATCCGCTCCGGCCTTTCCTTCCTGCCGCGATTCCCAACTTTGCTCAAAGTCGCTGGACTCTAAGC TGTCGGAGGGACCGCTGGACAGACCTGGGAACTGACAGAGGGCCTGGAGGGAAACAGGCCAAAGACCCAC AGGCAGAGTTGACACGGAACCCCAAAGCAAGGAGGAGGGCTCGGGCCCGAGACCGTTCACCTCCCCTTAT CCCTGTTCCCCTCTTCAGGATGGAGCTGACCTCAAGGGAAAGAGGGAGGGGACAGCCTCTGCCCTGGGAA CTTCGACTGGGCCTACTGCTAAGCGGTGAGAGGGCCTGGTGGGGGCTGGGGGTTGTGGAATGTGATGGTA GGTCCTGGTAGTTGCCCTTGGGGCACATGAGGTGGAGCCACTGGATAGGAACTCAGCGGAACTGACTGAG CTACTGTCCCCAGTGCTGGCTGCCACACTGGCACAGGCCCCTGCCCCGGATGTGCCTGGCTGTTCCAGGG GAAGCTGCTACCCCGCCACGGGCGACCTGCTGGTGGGCCGAGCTGACAGACTGACTGCCTCATCCACTTG TGGCCTGAATGGCCCCCAGCCCTACTGCATCGTCAGTCACCTGCAGGTGTGGCTGGGGACAGGGTGTGAC GCCGAGTCAGGGTGGGGCTGGCACTGCCTGAGGCACTGATTCTAATCCCCATCCAACCCAGGACGAAAAG AAGTGCTTCCTTTGTGACTCCCGGCGCCCCTTCTCTGCTAGAGACAACCCACACAGCCATCGCATCCAGA ATGTAGTCACCAGCTTTGCACCACAGCGGCGGGCAGCCTGGTGGCAGTCAGAGAATGGTGAGGCCATGGG TGGGGCAAAAGTGAGCAGGGCTGCCCACCAGTAGCTTTGAGTCCTTGACTTCCGATTCCTGTCCCAGGTA TCCCTGCGGTCACCATCCAGCTGGACCTGGAGGCTGAGTTTCATTTCACACACCTCATTATGACCTTCAA GGTGCCTGCATATCTGGGAGCCTGCCCGAATCACCCTGCTTGGCTCTCCATTGCCCCTGGACAGAGCCTC AGCTCCTTAACACAGCCTCCTTGAGCATGGATGCAGGAGGCTCCTTCATCCCTTCACACCTTCCATTTGC CTCCAGGCCTTTGCACATGCTCTTCTGCCTTTCCAATCCCAGGCTGGGTCAGGCGCTGTCTCCCTGAGCC CCATGAACCCTGAGTCTCCCCATTAGAGGTGGCTACCTTTGCTGGTCATTATCTGGCTTCCACCAGTCAC CCCCACTCTCTGTGAGCTATTTGAGGGCAGTCTTGGGCTGAGCAGGGCTCTTGATGGCTCTGGGTTGGGC TTGGGTCCTGGTGCCTGCTGATCAGCTATGCCCCCCTACCCAGACATTTCGCCCTGCTGCCATGCTGGTG GAACGCTCAGCAGACTTTGGCCGCACCTGGCATGTGTACCGATATTTCTCCTATGACTGTGGGGCTGACT TCCCAGGAGTCCCACTAGCACCCCCACGGCACTGGGATGATGTAGTCTGTGAGTCCCGCTACTCAGAGAT TGAGCCATCCACTGAAGGCGAGGTGAGGGCTGGCATCTGGGCTGGGGGCTGGAAGCTGGGGATGATGGGC CTGAGGCAAGGTCCAGTGTGACTATGAACTCCCTGCTTCTCCAGGTCATCTATCGTGTGCTGGACCCTGC CATCCCTATCCCAGACCCCTACAGCTCACGGATTCAGAGTGAGTGCTCCACCCTTTGAGTCTGGCACAGT CCGTGTCCGGCTAGGGACTATTTGGGGCCTCAGTAACTATTTTGGGTGCTTCCTAGGGCAGGTGCCAAGC CCAGTTTAGCTCGGGTGGCAGTGTATAGGAGGTCTTTCAAGGTGACCTTGGCAGCTGAGCCCCTGGGTGG ACATGGGGCAGCAAGGGCCTGCCTGGTCAGTTGGCCCCCCTTCCCCCGCCTCAGACCTGTTGAAGATCAC CAACCTACGGGTGAACCTGACTCGTCTACACACGTTGGGAGACAACCTACTCGACCCACGGAGGGAGATC CGAGAGAAGTACTACTATGCCCTCTATGAGCTGGTTGTACGTGGCAACTGCTTCTGCTACGGACACGCCT CAGAGTGTGCACCCGCCCCAGGGGCACCAGCCCATGCTGAGGGCATGGTAAGGGGCTTCAGACGGTTGGG ATAGGGCTAGGGGCAGGGGCGGACATGGCTGAGCAGTGCTGACAACCTACCTGCCAACCTCTATAGGTGC ACGGAGCTTGCATCTGCAAACACAACACACGTGGCCTCAACTGCGAGCAGTGTCAGGATTTCTATCGTGA CCTGCCCTGGCGTCCGGCTGAGGACGGCCATAGTCATGCCTGTAGGAGTGAGTGAGATCTTGGCCTCCAT AGCTCCAGCACTCTGCAGCCTGGCTGTGCCCTGGGTAGAACCTAGAGCTAGTTGGTCAAGCCCCTAAAAC CCAGGCTGTATCCAAAGAGTATGCAGACCTTGATGCCCCTTGGGACCCCCTCAATCCTCCTCTGCAGTCT GCTCTGGGTAGGGAACCAGTATGATGCTGAGGCCTTGAAGTCCCTGAGCCCCTACCCACAAATTCTGGCC TGTGATAGGGATCTAAGGTGGCCTACTTCTTACCCTTGTGACCTGGTTCCTCATGTGGCCTTTGCCCTGC CCTTCCTCCCCTGCCAGAGTGTGAGTGCCATGGGCACACCCACAGCTGCCACTTCGACATGGCCGTATAC CTGGCATCTGGCAATGTGAGTGGAGGTGTGTGTGATGGATGTCAGCATAACACAGCTGGGCGCCACTGTG AGCTCTGTCGGCCCTTCTTCTACCGTGACCCAACCAAGGACCTGCGGGATCCGGCTGTGTGCCGCTGTGA GGCTGGGATTGGGCACGGGGAGAGAAAGCTGAGCCTGGGGCAGGAACTAGAGAGCTGGACTGCTGTCTAA ATTGCAGGAAATTGGGGTTAGGGGCTTGGGATAGAACTTGACCAGGGATCCAGGGTGGGATCCCTTAGGC TTAGGAGAGGACTGGCAGTGAGCTAGTTGAGATAGGGTGAGTGACCCTGTATCTCTTTTTGCCGTCAGCC TGTGATTGTGACCCCATGGGTTCTCAAGACGGTGGTCGCTGTGATTCCCATGATGACCCTGCACTGGGAC TGGTCTCCGGCCAGTGTCGCTGCAAAGAACATGTGGTGGGCACTCGCTGCCAGCAATGCCGTGATGGCTT CTTTGGGCTCAGCATCAGTGACCGTCTGGGCTGCCGGCGTATGTGTCTCCTGCCCTAACTTCTATGCTGA CCTTTAACCCCTGTCCTCTTACTCCTGACTCAGCTGAACATGAGCACTGCCACAGTTTCCCAAAGTGCTG ATGGTTCTCCTTCCCTGCAGGATGTCAATGTAATGCACGGGGCACAGTGCCTGGGAGCACTCCTTGTGAC CCCAACAGTGGATCCTGTTACTGCAAACGTCTAGTGACTGGACGTGGATGTGACCGCTGCCTGGTGCGAC TGGAAGGGGCTGGAGTTCTAGGGGCATGATTTGTCCTTAGAGCACAGGGCTGGGGTGTCACATCTATGCC AGTGGGTGGGTGCTGAGAGCTTAGGATCCAGTCCTGGCTGAGAAGCCTCAGGTCTGGGAGGCCAAGGATG TGGGCCAGTGGTCTGGGGGGCATGTTTTCACTGAGGGGTGATTGAGGCTAAGACGTGTGGTTGGGATTTC CTGCTGGGTGGTGATGGGGTCTGGAGGTCTGTTTCTGGCCCCCAGCAACTCCTTTCGTGCAGCCTGGCCA CTGGGGCCTGAGCCACGACCTGCTCGGCTGCCGCCCCTGTGACTGCGACGTGGGTGGTGCTTTGGATCCC CAGTAAGTGTTGTAAAGGGGGCCTGGGAAGGGATGGGGAAAGATCCTGAGCAGAAGAGAAGGTTCTTCTT GAGTAACCACAGAGTTCCCTCCAGGTGTGATGAGGGCACAGGTCAATGCCACTGCCGCCAGCACATGGTT GGGCGACGCTGTGAGCAGGTGCAACCTGGCTACTTCCGGCCCTTCCTGGACCACCTAATTTGGGAGGCTG AGGACACCCGAGGGCAGGTGTGGGGCCTCCCCCTAAGCAGAGGGCTGGATGTGGGTGGACACGTCTATGA CTGGAGAGGTGGGGTTATGGGCAGTACCTTGTTGAGGGGATAGGGGTGATATCTAGCTTTGGCAGGAGAA ATGGGGTTTGGGGCTGGCTGTGGCAGAAGAGGCAAAGCCTCACCTGAGCCTCCATCCCTGGCTGCATTAT CTCCCAGGTGCTCGATGTGGTGGAGCGCCTGGTGACCCCCGGGGAAACTCCATCCTGGACTGGCTCAGGC TTCGTGCGGCTACAGGAAGGTCAGACCCTGGAGTTCCTGGTGGCCTCTGTGCCGAAGGCTATGGACTATG ACCTGCTGCTGCGCTTAGAGCCCCAGGTTAGACCCTGTTATCTAATCTGGGGCTGAACCTCTGGGTGTGG GAGCATCTCCTCCATCATCCCGTTTTCCCAGGTCCCTGAGCAATGGGCAGAGTTGGAACTGATTGTGCAG CGTCCAGGGCCTGTGCCTGCCCACAGCCTGTGTGGGCATTTGGTGCCCAAGGATGATCGCATCCAAGGGA CTCTGCAACCACATGCCAGGTGAGGGCACTGGTGGTAGCACTCACAATGGCAGGGGGTTGTGGGGCCAGC CCTAAGCTCCCTGCAGGGCACCTGGAAGACCCCACAGCTCATTCATCTGTTCCTTCTTTCAAATACCTCC AGAATGCTGGTTGCCAGGCCCTGTTGGGCATGGCTCTGTTCACAGAAAGGAAGTAGACAGATCAAGGCCT GCTCTCTCAGGGGTCTAAGGCCCAGAGGCCAAGGCAGGAATTAATGGGAAATCACCTGGTGTCACTATCA GGAGGGTCCACAGTGGTGGTGGTAGAGGGTGGTAGTGGTGGGGTTGTGGCATCAGAGCACTCTGAGCAGG GATGTGCCTGGTCTGATTAATGTTTTATTACATTTTGGGTAGTATTTGTTTCATGTTTCATGTTTCTTTT TTTTTTCTTTTCTTTTCTTTTTTTTTTTTTTTTTTTTTGAGACGGAGTCTCGCTCTGTCACCAGGCTGGA GTGCAGTGGTGCGATCTCGGCTCACTGTAATCTCCACCTCCCGGGTTCAAGCAATTCTCATGTGTCAGCA TCCCGAGTAGCTGGGACTACAGGTGCACGCCACCACGCCCAGCTAGTTTTTTGTATTTTTAGTAGAGATG GGGTTTCACCATGTTGGCCAGGATGGCCTCGATCTTCTGACCTTGTGATCTGCCCGCCTTGGCCTCCCAA AGTGTTGGGATTACAGGTGTGAGCCACCGTGCCCAGCCCTGTTTCATTGTTTCATGTTTTGTTTGTTTGT TTGTTTGTTTTTGAGATGGAGTCTTGCTCTGTCGCCCAGGCTGGAGTGCACTGGCGCGATCTCGGCTCAC TGCAAGCTCCACCTCCCAGGTTCACGCCATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGACCACAGGCA CCCGCCACCATGCCTTGCTAATTTTTTGTATTTTTAGTAGAGACGGGGTTTCACCATGTTAGCCAGGATG GTCTCGATCTCCTGACCTTGTGATCCACCTTTCTCGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAACC ACTGCACTTGACCTATTGCTTTTAGTTTTTGACCATGTAAATATTCAAACAGAAGGAAAGAGAATAACAT ATTGAACCTGGCTGTGCCCATTATAGACATTTTGCCAACTGTGACTTGTGTTTAGAAAAAAAATTCCTCT AGACCAGGCATGGTGGCTCATGCCTGTAATCCCAGCACTTTGGGACACTGAGGCAGGAGGATCACTTGAG CCCAGGAATTCAAGACCAGCCTAGGCAACATGGCGAGACCCTGTCTCTACAAAAAATAAAATAATTAGCT AAGCATGGTGGTGTGTGCTTGTGGTTCCAGCTGCTTGGGAGGCTGAGGTGGGAGGATATCTTGAACCCAG GAGGTCAAGGCTGCAGTGAGCCAAGGTCACGCACTGTACTCCATCCATCCTGGGCAACAGAGACCGCATC TCAAATAAACAAATAAATAAATAAATCAGAAAATAAAAAGAAAAAAGATGAGGGATTGAAGAACAATTTT TGGGATGGGATAAAAGAACCCAAGTATGAGTTTGCAGCACAATGGGAAAGGAAAGCCTTGGAGACAAAGA GAGAGGGGGCGACATAGTGTTGATGAAGAGGAGCAGCCATTGTAGGTTGTAGGTCGGGGTCAGAGGAAGC GTGAGGTGGTTGTTGAGGAGAATTGGCAAGTTCTTGGGATTTCCAGGCTTTATGAGTATTTCCAGTGAGT CTGCACAGGTGGATGTATGATTCTAGAGGGCCACCTTTATGAGACTATTCTGTGCAGATTCTTTGTTGGG CTGCCCAGCTGTTTGTTGGCCTAGCGCAGCCCAACGCAACCCAGCCATAGTCTCTGCTTTGGCCAATGGC CTGGTTGCTGGGAGAAGGATGGGGGAGGCCCAGATGATTTGTACAGGGCCCCTAGATGACCCACTGCACC TGTCCCCACTCGCCCCCAGGTACTTGATATTTCCTAATCCTGTCTGCCTTGAGCCTGGTATCTCCTACAA GCTGCATCTGAAGCTGGTACGGACAGGGGGAAGTGCCCAGCCTGAGACTCCCTACTCTGGACCTGGCCTG CTCATTGACTCGGTGAATAATCTCCTCTTGCCCACACCAACCAAGATGGCAGGGCCCGTGGTGTGGGACT TGAGGGATAGCAGGGGTCTGTGGCAGAAGAGGCAGGCCCATGGTGGTGCCAGGGTGGGCAGGCTTGTGGC AGTGCTAAGGCAAGTGCTCTGGCAATGCCTACGTGGTCCCAGGTCTGAACTGCGATCTTCCTTGCTCACT CCTTCAGCTGGTGCTGCTGCCCCGTGTCCTGGTGCTAGAGATGTTTAGTGGGGGTGATGCTGCTGCCCTG GAGCGCCAGGCCACCTTTGAACGCTACCAATGCCATGAGGAGGGTCTGGTGCCCAGCAAGACTTCTCCCT CTGAGGCCTGCGCACCCCTCCTCATCAGCCTGTCCACCCTCATCTACAATGGTGCCCTGCGTGAGTGTCT GTGATGTGGGTTGATGGGGCAGAGGTGGGGACCCAGCCTGACTTGGCCCAACCCTCCTCCCCACAGCATG TCAGTGCAACCCTCAAGGTTCACTGAGTTCTGAGTGCAACCCTCATGGTGGTCAGTGCCTGTGCAAGCCT GGAGTGGTTGGGCGCCGCTGTGACCTCTGTGCCCCTGGCTACTATGGCTTTGGCCCCACAGGCTGTCAAG GTACTCTTCTGCCCCTTGTTCCCTCCTATGCTTCTCTCTCCTTCCCATTACTGTTCTCTCTCCTCCTTCT GGACCTGCTGCTGGTTTCCTCAAACTAAGTCTTGGACCCTCTACTCTCAACCTGGGTCAGTTGTAGTTCT CTTCCATTTCCTGACCTTCCCACCTAGACTCCCACTACTCACACTCCCCTGAGACCCTCCCCCACCCACA CTCCCCTCAGACCCCCTCCCCTGGCTCTGGCTCAGCTCTGCCTTGCTCCTAGCCTGCCAGTGCAGCCACG AGGGGGCACTCAGCAGTCTCTGTGAAAAGACCAGTGGGCAATGTCTCTGTCGAACTGGTGCCTTTGGGCT TCGCTGTGACCGCTGCCAGCGTGGCCAGTGGGGATTCCCTAGCTGCCGGCCATGTGTCTGCAATGGGCAT GCAGATGAGTGCAACACCCACACAGGCGCTTGCCTGGGCTGCCGTGATCACACAGGGGGTGAGCACTGTG AAAGGTGAGACTGGAGCAGCTATGAGTGGGTTGGTTGGTGGGCAGGCTTCCCAGGGATGACACATTTCTT CTTCCTCCTCCCTGCAGGTGCATTGCTGGTTTCCACGGGGACCCACGGCTGCCATATGGGGGCCAGTGCC GGCCCTGTCCCTGTCCTGAAGGCCCTGGGAGCCAACGGCACTTTGCTACTTCTTGCCACCAGGATGAATA TTCCCAGCAGATTGTGTGCCACTGCCGGGCAGGCTATACGGGTGAGTGGATGGGGGCAGGCGTGGGATCA GGGTGAGTTGGCTGGGCTGAGCACTCACAGCTTCCTCTTAACCGTGGGCAGGGCTGCGATGTGAAGCTTG TGCCCCTGGGCACTTTGGGGACCCATCAAGGCCAGGTGGCCGGTGCCAACTGTGTGAGTGCAGTGGGAAC ATTGACCCAATGGATCCTGATGCCTGTGACCCCCACACGGGGCAATGCCTGCGCTGTTTACACCACACAG AGGGTCCACACTGTGCCCACTGCAAGCCTGGCTTCCATGGGCAGGCTGCCCGACAGAGCTGTCACCGTGA GTATGAGTGTGGGAGGGCATGGCTGAATTGGGGTTCTGCTTCTTGGCCTCCTCTTGACTACTGTGCTCAT CTTGGTTGGCACAGGCTGCACATGCAACCTGCTGGGCACAAATCCGCAGCAGTGCCCATCTCCTGACCAG TGCCACTGTGATCCAAGCAGTGGGCAGTGCCCATGCCTCCCCAATGTCCAGGGCCCTAGCTGTGACCGCT GTGCCCCCAACTTCTGGAACCTCACCAGTGGCCATGGTTGCCAGCCTTGTGCCTGCCACCCAAGCCGGGC CAGAGGCCCCACCTGCAACGAGGTATGGGACCCTCCTGCAGATCCCTGGTTAGATGGGGCCAGGTGTCTG TCTTATCTCCAGGGCTTAGCCTCTTATAGAGGCTCTGACCCTGCCTTGTTCCCACCCCAGTTCACAGGGC AGTGCCACTGCCGTGCCGGCTTTGGAGGGCGGACTTGTTCTGAGTGCCAAGAGCTCCACTGGGGAGACCC TGGGTTGCAGTGCCATGGTGAGGGAGCCAGCGGGGCCAGGGTAGATGGAGGACTTCCCAGAATGCCCCAC AGTGACCCTAACTCTGTGCTCTGCTCTTTCTTGCAGCCTGTGATTGTGACTCTCGTGGAATAGATACACC TCAGTGTCACCGCTTCACAGGTCACTGCAGCTGCCGCCCAGGGGTGTCTGGTGTGCGCTGTGACCAGTGT GCCCGTGGCTTCTCAGGAATCTTTCCTGCCTGCCATCCCTGCCATGCATGCTTCGGGGATTGGGACCGAG TGGTGCAGGACTTGGCAGCCCGTACACAGCGCCTAGAGCAGCGGGCGCAGGAGTTGCAACAGACGGGTGT GCTGGGTGCCTTTGAGAGCAGCTTCTGGCACATGCAGGAGAAGCTGGGCATTGTGCAGGGCATCGTAGGT GCCCGCAACACCTCAGCCGCCTCCACTGCACAGCTTGTGGAGGCCACAGAGGAGCTGCGGTGCGGAAGGG CCTAAGAATACATGGTGGGATGGGGCAGAGGCCCAGTGGACCAGGGCTGAAGCCTCTCTAAACACCCCCC TCTCCATCATTGCAGGCGTGAAATTGGGGAGGCCACTGAGCACCTGACTCAGCTCGAGGCAGACCTGACA GATGTGCAAGATGAGAACTTCAATGCCAACCATGCACTAAGTGGTCTGGAGCGAGATAGGCTTGCACTTA ATCTCACACTGCGGCAGCTCGACCAGCATCTTGACTTGCTCAAACATTCAAACTTCCTGGGTGAGTTGTT AGCCAACTAGGCAGGTGGACCAGGGTCAGTCTTCAGCTGACTGTCTGCCTCTGCCCAATTTAGGTGCCTA TGACAGCATCCGGCATGCCCATAGCCAGTCTGCAGAGGCAGAACGTCGTGCCAATACCTCAGCCCTGGCA GTACCTAGCCCTGTGAGCAACTCGGCAAGTGCTCGGCATCGGACAGAGGCACTGATGGATGCTCAGAAGG AGGACTTCAACAGCAAACACATGGCCAACCAGCGGGCACTTGGCAAGCTCTCTGCCCATACCCACACCCT GAGCCTGACAGACATAAATGAGCTGGTGAGGTTGAAGTGTTGGGTGGGGCAGGTGGGTGTAGATGTTCCT CTCACAGGGCCCTGACTTGTTCTGTGCCTGGCAGGTGTGTGGGGCACCAGGGGATGCACCCTGTGCTACA AGCCCTTGTGGGGGTGCCGGCTGTCGAGATGAGGATGGGCAGCCGCGCTGTGGGGGCCTCAGCTGCAATG GGGCAGCGGCTACAGCAGACCTAGCACTGGGCCGGGCCCGGCACACACAGGCAGAGCTGCAGCGGGCACT GGCAGAAGGTGGTAGCATCCTCAGCAGAGTGGCTGAGACTCGTCGGCAGGCAAGCGAGGCACAGCAGCGG GCCCAGGCAGCCCTGGACAAGGCTAATGCTTCCAGGGGACAGGTGGAACAGGCCAACCAGGAACTTCAAG AACTTATCCAGAGTGTGAAGGACTTCCTCAACCGTGAGCCTCCCACGTGTCCCAGGCCATGTGGTTGTCC CCTTTGGCAACTCCCGGTGTCTGTATCTCCCTTGGTTCATACTTGAGCCTCAGGGACTACACTGGATTAG TGTTTATGATCCCTTGACTGGCTCCTGAGTTATTGCCCATATGTGGTCCCAGGTCCATGTTCTTGAGTCT GAGCCCCTTGTATAGTCCCTGTCCTTGTGATTATATCCTTATGCCTGGTAACAAACCCCTATCCCATGTA CATGTCCTGAGTCCATACCCCAAAACTGTATCCTCATGCCCATGCTGGAGAATCTATGTTCTTAAGTTCT TGCTGTGTCCCTATAGAGGAGGGGGCTGATCCTGATAGCATTGAAATGGTGGCCACACGGGTGCTAGAGC TCTCCATCCCAGCTTCAGCTGAGCAGATCCAGCACCTGGCGGGTGCGATTGCAGAGCGAGTCCGGAGCCT GGCAGATGTGGATGCGATCCTGGCACGTACTGTAGGAGATGTGCGTCGTGCCGAGCAGCTACTGCAGGAT GCACGGCGGGCAAGGTCTGACCCCATCCCTGGCCCCTATCCCTGACACCTGGTTTTGATACCTCCAGGTT CTGATTCCCCCTTCTCCCCAGGAGCTGGGCTGAGGATGAGAAACAGAAGGCAGAGACAGTACAGGCAGCA CTGGAGGAGGCCCAGCGGGCACAGGGTATTGCCCAGGGTGCCATCCGGGGGGCAGTGGCTGACACACGGG ACACAGAGCAGACCCTGTACCAGGTGAGGTCTTCCTAGGACATCAGTGGGACAAGGTTATGGGCATGAAC CGTAGATCTGTGTAACCTTTGGCTCACCCATGGCAGGTACAGGAGAGGATGGCAGGTGCAGAGCGGGCAC TGAGCTCTGCAGGTGAAAGGGCTCGGCAGTTGGATGCTCTCCTGGAGGCTCTGAAATTGAAACGGGCAGG AAATAGTCTGGCAGCCTCTACAGCAGAAGAAACGGCAGGCAGTGCCCAGGGTCGTGCCCAGGAGGCTGAG CAGGTGGGTTGAGGCAGAGCCAGCTGGAGAAGGTAGGGGTGGAAGATGGGCCTCCACTGAGCTACCACGC TAACCTAACCCTCTACATCTGCAGCTGCTACGCGGTCCTCTGGGTGATCAGTACCAGACGGTGAAGGCCC TAGCTGAGCGCAAGGCCCAAGGTGTGCTGGCTGCACAGGCAAGGGCAGAACAACTGCGGGATGAGGCTCG GGACCTGTTGCAAGCCGCTCAGGACAAGCTGCAGCGGCTACAGGGTAAGAAATGGGGCACCAGAGACACA AGACTGCGGGAAACCCCCCCTAAACTGACACCTGCCCTTCCTAGAATTGGAAGGCACCTATGAGGAAAAT GAGCGGGCACTGGAGAGTAAGGCAGCCCAGTTGGACGGGTTGGAGGCCAGGATGCGCAGCGTGCTTCAAG CCATCAACTTGCAGGTGCAGATCTACAACACCTGCCAGTGACCCCTGCCCAAGGCCTACCCCAGTTCCTA GCACTGCCCCACATGCATGTCTGCCTATGCACTGAAGAGCTCTTGGCCCGGCAGGGCCCCCAATAAACCA GTGTGAACCCCCA    Download   Select all
Length	12053
OMIM ID	150325
HGNC ID	HGNC:6487
Unigene ID	Hs.439726
Ensembl ID	ENSG00000172037
PharmGKB ID	-

mRNA Information

mRNA ID	NM_002292.3
Exon	join(1..375,504..676,762..897,978..1051,1444..1632, 1725..1788,2015..2217,2307..2427,2748..2936,3149..3328, 3451..3563,3843..3922,4015..4147,4348..4506,4582..4709, 6670..6802,7008..7200,7277..7420,7683..7914,7998..8161, 8242..8466,8555..8772,8881..8977,9067..9439,9536..9720, 9794..10035,10115..10463,10797..11004,11082..11223, 11307..11483,11575..11734,11805..12053)
mRNA Sequence	>3913 GAAGGCAGTTTCCGGAGGGAAGGGGTAGGGTTGGGGTGGGGGCGCTCTCCGCCCGGTGTTGCGC TCCTTCCCAGAATCCGCTCCGGCCTTTCCTTCCTGCCGCGATTCCCAACTTTGCTCAAAGTCGC TGGACTCTAAGCTGTCGGAGGGACCGCTGGACAGACCTGGGAACTGACAGAGGGCCTGGAGGGA AACAGGCCAAAGACCCACAGGCAGAGTTGACACGGAACCCCAAAGCAAGGAGGAGGGCTCGGGC CCGAGACCGTTCACCTCCCCTTATCCCTGTTCCCCTCTTCAGGATGGAGCTGACCTCAAGGGAA AGAGGGAGGGGACAGCCTCTGCCCTGGGAACTTCGACTGGGCCTACTGCTAAGCGTGCTGGCTG CCACACTGGCACAGGCCCCTGCCCCGGATGTGCCTGGCTGTTCCAGGGGAAGCTGCTACCCCGC CACGGGCGACCTGCTGGTGGGCCGAGCTGACAGACTGACTGCCTCATCCACTTGTGGCCTGAAT GGCCCCCAGCCCTACTGCATCGTCAGTCACCTGCAGGACGAAAAGAAGTGCTTCCTTTGTGACT CCCGGCGCCCCTTCTCTGCTAGAGACAACCCACACAGCCATCGCATCCAGAATGTAGTCACCAG CTTTGCACCACAGCGGCGGGCAGCCTGGTGGCAGTCAGAGAATGGTATCCCTGCGGTCACCATC CAGCTGGACCTGGAGGCTGAGTTTCATTTCACACACCTCATTATGACCTTCAAGACATTTCGCC CTGCTGCCATGCTGGTGGAACGCTCAGCAGACTTTGGCCGCACCTGGCATGTGTACCGATATTT CTCCTATGACTGTGGGGCTGACTTCCCAGGAGTCCCACTAGCACCCCCACGGCACTGGGATGAT GTAGTCTGTGAGTCCCGCTACTCAGAGATTGAGCCATCCACTGAAGGCGAGGTCATCTATCGTG TGCTGGACCCTGCCATCCCTATCCCAGACCCCTACAGCTCACGGATTCAGAACCTGTTGAAGAT CACCAACCTACGGGTGAACCTGACTCGTCTACACACGTTGGGAGACAACCTACTCGACCCACGG AGGGAGATCCGAGAGAAGTACTACTATGCCCTCTATGAGCTGGTTGTACGTGGCAACTGCTTCT GCTACGGACACGCCTCAGAGTGTGCACCCGCCCCAGGGGCACCAGCCCATGCTGAGGGCATGGT GCACGGAGCTTGCATCTGCAAACACAACACACGTGGCCTCAACTGCGAGCAGTGTCAGGATTTC TATCGTGACCTGCCCTGGCGTCCGGCTGAGGACGGCCATAGTCATGCCTGTAGGAAGTGTGAGT GCCATGGGCACACCCACAGCTGCCACTTCGACATGGCCGTATACCTGGCATCTGGCAATGTGAG TGGAGGTGTGTGTGATGGATGTCAGCATAACACAGCTGGGCGCCACTGTGAGCTCTGTCGGCCC TTCTTCTACCGTGACCCAACCAAGGACCTGCGGGATCCGGCTGTGTGCCGCTCCTGTGATTGTG ACCCCATGGGTTCTCAAGACGGTGGTCGCTGTGATTCCCATGATGACCCTGCACTGGGACTGGT CTCCGGCCAGTGTCGCTGCAAAGAACATGTGGTGGGCACTCGCTGCCAGCAATGCCGTGATGGC TTCTTTGGGCTCAGCATCAGTGACCGTCTGGGCTGCCGGCGATGTCAATGTAATGCACGGGGCA CAGTGCCTGGGAGCACTCCTTGTGACCCCAACAGTGGATCCTGTTACTGCAAACGTCTAGTGAC TGGACGTGGATGTGACCGCTGCCTGCCTGGCCACTGGGGCCTGAGCCACGACCTGCTCGGCTGC CGCCCCTGTGACTGCGACGTGGGTGGTGCTTTGGATCCCCAGTGTGATGAGGGCACAGGTCAAT GCCACTGCCGCCAGCACATGGTTGGGCGACGCTGTGAGCAGGTGCAACCTGGCTACTTCCGGCC CTTCCTGGACCACCTAATTTGGGAGGCTGAGGACACCCGAGGGCAGGTGCTCGATGTGGTGGAG CGCCTGGTGACCCCCGGGGAAACTCCATCCTGGACTGGCTCAGGCTTCGTGCGGCTACAGGAAG GTCAGACCCTGGAGTTCCTGGTGGCCTCTGTGCCGAAGGCTATGGACTATGACCTGCTGCTGCG CTTAGAGCCCCAGGTCCCTGAGCAATGGGCAGAGTTGGAACTGATTGTGCAGCGTCCAGGGCCT GTGCCTGCCCACAGCCTGTGTGGGCATTTGGTGCCCAAGGATGATCGCATCCAAGGGACTCTGC AACCACATGCCAGGTACTTGATATTTCCTAATCCTGTCTGCCTTGAGCCTGGTATCTCCTACAA GCTGCATCTGAAGCTGGTACGGACAGGGGGAAGTGCCCAGCCTGAGACTCCCTACTCTGGACCT GGCCTGCTCATTGACTCGCTGGTGCTGCTGCCCCGTGTCCTGGTGCTAGAGATGTTTAGTGGGG GTGATGCTGCTGCCCTGGAGCGCCAGGCCACCTTTGAACGCTACCAATGCCATGAGGAGGGTCT GGTGCCCAGCAAGACTTCTCCCTCTGAGGCCTGCGCACCCCTCCTCATCAGCCTGTCCACCCTC ATCTACAATGGTGCCCTGCCATGTCAGTGCAACCCTCAAGGTTCACTGAGTTCTGAGTGCAACC CTCATGGTGGTCAGTGCCTGTGCAAGCCTGGAGTGGTTGGGCGCCGCTGTGACCTCTGTGCCCC TGGCTACTATGGCTTTGGCCCCACAGGCTGTCAAGCCTGCCAGTGCAGCCACGAGGGGGCACTC AGCAGTCTCTGTGAAAAGACCAGTGGGCAATGTCTCTGTCGAACTGGTGCCTTTGGGCTTCGCT GTGACCGCTGCCAGCGTGGCCAGTGGGGATTCCCTAGCTGCCGGCCATGTGTCTGCAATGGGCA TGCAGATGAGTGCAACACCCACACAGGCGCTTGCCTGGGCTGCCGTGATCACACAGGGGGTGAG CACTGTGAAAGGTGCATTGCTGGTTTCCACGGGGACCCACGGCTGCCATATGGGGGCCAGTGCC GGCCCTGTCCCTGTCCTGAAGGCCCTGGGAGCCAACGGCACTTTGCTACTTCTTGCCACCAGGA TGAATATTCCCAGCAGATTGTGTGCCACTGCCGGGCAGGCTATACGGGGCTGCGATGTGAAGCT TGTGCCCCTGGGCACTTTGGGGACCCATCAAGGCCAGGTGGCCGGTGCCAACTGTGTGAGTGCA GTGGGAACATTGACCCAATGGATCCTGATGCCTGTGACCCCCACACGGGGCAATGCCTGCGCTG TTTACACCACACAGAGGGTCCACACTGTGCCCACTGCAAGCCTGGCTTCCATGGGCAGGCTGCC CGACAGAGCTGTCACCGCTGCACATGCAACCTGCTGGGCACAAATCCGCAGCAGTGCCCATCTC CTGACCAGTGCCACTGTGATCCAAGCAGTGGGCAGTGCCCATGCCTCCCCAATGTCCAGGGCCC TAGCTGTGACCGCTGTGCCCCCAACTTCTGGAACCTCACCAGTGGCCATGGTTGCCAGCCTTGT GCCTGCCACCCAAGCCGGGCCAGAGGCCCCACCTGCAACGAGTTCACAGGGCAGTGCCACTGCC GTGCCGGCTTTGGAGGGCGGACTTGTTCTGAGTGCCAAGAGCTCCACTGGGGAGACCCTGGGTT GCAGTGCCATGCCTGTGATTGTGACTCTCGTGGAATAGATACACCTCAGTGTCACCGCTTCACA GGTCACTGCAGCTGCCGCCCAGGGGTGTCTGGTGTGCGCTGTGACCAGTGTGCCCGTGGCTTCT CAGGAATCTTTCCTGCCTGCCATCCCTGCCATGCATGCTTCGGGGATTGGGACCGAGTGGTGCA GGACTTGGCAGCCCGTACACAGCGCCTAGAGCAGCGGGCGCAGGAGTTGCAACAGACGGGTGTG CTGGGTGCCTTTGAGAGCAGCTTCTGGCACATGCAGGAGAAGCTGGGCATTGTGCAGGGCATCG TAGGTGCCCGCAACACCTCAGCCGCCTCCACTGCACAGCTTGTGGAGGCCACAGAGGAGCTGCG GCGTGAAATTGGGGAGGCCACTGAGCACCTGACTCAGCTCGAGGCAGACCTGACAGATGTGCAA GATGAGAACTTCAATGCCAACCATGCACTAAGTGGTCTGGAGCGAGATAGGCTTGCACTTAATC TCACACTGCGGCAGCTCGACCAGCATCTTGACTTGCTCAAACATTCAAACTTCCTGGGTGCCTA TGACAGCATCCGGCATGCCCATAGCCAGTCTGCAGAGGCAGAACGTCGTGCCAATACCTCAGCC CTGGCAGTACCTAGCCCTGTGAGCAACTCGGCAAGTGCTCGGCATCGGACAGAGGCACTGATGG ATGCTCAGAAGGAGGACTTCAACAGCAAACACATGGCCAACCAGCGGGCACTTGGCAAGCTCTC TGCCCATACCCACACCCTGAGCCTGACAGACATAAATGAGCTGGTGTGTGGGGCACCAGGGGAT GCACCCTGTGCTACAAGCCCTTGTGGGGGTGCCGGCTGTCGAGATGAGGATGGGCAGCCGCGCT GTGGGGGCCTCAGCTGCAATGGGGCAGCGGCTACAGCAGACCTAGCACTGGGCCGGGCCCGGCA CACACAGGCAGAGCTGCAGCGGGCACTGGCAGAAGGTGGTAGCATCCTCAGCAGAGTGGCTGAG ACTCGTCGGCAGGCAAGCGAGGCACAGCAGCGGGCCCAGGCAGCCCTGGACAAGGCTAATGCTT CCAGGGGACAGGTGGAACAGGCCAACCAGGAACTTCAAGAACTTATCCAGAGTGTGAAGGACTT CCTCAACCAGGAGGGGGCTGATCCTGATAGCATTGAAATGGTGGCCACACGGGTGCTAGAGCTC TCCATCCCAGCTTCAGCTGAGCAGATCCAGCACCTGGCGGGTGCGATTGCAGAGCGAGTCCGGA GCCTGGCAGATGTGGATGCGATCCTGGCACGTACTGTAGGAGATGTGCGTCGTGCCGAGCAGCT ACTGCAGGATGCACGGCGGGCAAGGAGCTGGGCTGAGGATGAGAAACAGAAGGCAGAGACAGTA CAGGCAGCACTGGAGGAGGCCCAGCGGGCACAGGGTATTGCCCAGGGTGCCATCCGGGGGGCAG TGGCTGACACACGGGACACAGAGCAGACCCTGTACCAGGTACAGGAGAGGATGGCAGGTGCAGA GCGGGCACTGAGCTCTGCAGGTGAAAGGGCTCGGCAGTTGGATGCTCTCCTGGAGGCTCTGAAA TTGAAACGGGCAGGAAATAGTCTGGCAGCCTCTACAGCAGAAGAAACGGCAGGCAGTGCCCAGG GTCGTGCCCAGGAGGCTGAGCAGCTGCTACGCGGTCCTCTGGGTGATCAGTACCAGACGGTGAA GGCCCTAGCTGAGCGCAAGGCCCAAGGTGTGCTGGCTGCACAGGCAAGGGCAGAACAACTGCGG GATGAGGCTCGGGACCTGTTGCAAGCCGCTCAGGACAAGCTGCAGCGGCTACAGGAATTGGAAG GCACCTATGAGGAAAATGAGCGGGCACTGGAGAGTAAGGCAGCCCAGTTGGACGGGTTGGAGGC CAGGATGCGCAGCGTGCTTCAAGCCATCAACTTGCAGGTGCAGATCTACAACACCTGCCAGTGA CCCCTGCCCAAGGCCTACCCCAGTTCCTAGCACTGCCCCACATGCATGTCTGCCTATGCACTGA AGAGCTCTTGGCCCGGCAGGGCCCCCAATAAACCAGTGTGAACCCCCAAAAAAAAAA    Download   Select all
Length	5817

CDS Information

   

Location	join(300..375,504..676,762..897,978..1051,1444..1632, 1725..1788,2015..2217,2307..2427,2748..2936,3149..3328, 3451..3563,3843..3922,4015..4147,4348..4506,4582..4709, 6670..6802,7008..7200,7277..7420,7683..7914,7998..8161, 8242..8466,8555..8772,8881..8977,9067..9439,9536..9720, 9794..10035,10115..10463,10797..11004,11082..11223, 11307..11483,11575..11734,11805..11941)
CDS Sequence	>gi|119703754:300-5696 Homo sapiens laminin, beta 2 (laminin S) (LAMB2), mRNA ATGGAGCTGACCTCAAGGGAAAGAGGGAGGGGACAGCCTCTGCCCTGGGAACTTCGACTGGGCCTACTGC TAAGCGTGCTGGCTGCCACACTGGCACAGGCCCCTGCCCCGGATGTGCCTGGCTGTTCCAGGGGAAGCTG CTACCCCGCCACGGGCGACCTGCTGGTGGGCCGAGCTGACAGACTGACTGCCTCATCCACTTGTGGCCTG AATGGCCCCCAGCCCTACTGCATCGTCAGTCACCTGCAGGACGAAAAGAAGTGCTTCCTTTGTGACTCCC GGCGCCCCTTCTCTGCTAGAGACAACCCACACAGCCATCGCATCCAGAATGTAGTCACCAGCTTTGCACC ACAGCGGCGGGCAGCCTGGTGGCAGTCAGAGAATGGTATCCCTGCGGTCACCATCCAGCTGGACCTGGAG GCTGAGTTTCATTTCACACACCTCATTATGACCTTCAAGACATTTCGCCCTGCTGCCATGCTGGTGGAAC GCTCAGCAGACTTTGGCCGCACCTGGCATGTGTACCGATATTTCTCCTATGACTGTGGGGCTGACTTCCC AGGAGTCCCACTAGCACCCCCACGGCACTGGGATGATGTAGTCTGTGAGTCCCGCTACTCAGAGATTGAG CCATCCACTGAAGGCGAGGTCATCTATCGTGTGCTGGACCCTGCCATCCCTATCCCAGACCCCTACAGCT CACGGATTCAGAACCTGTTGAAGATCACCAACCTACGGGTGAACCTGACTCGTCTACACACGTTGGGAGA CAACCTACTCGACCCACGGAGGGAGATCCGAGAGAAGTACTACTATGCCCTCTATGAGCTGGTTGTACGT GGCAACTGCTTCTGCTACGGACACGCCTCAGAGTGTGCACCCGCCCCAGGGGCACCAGCCCATGCTGAGG GCATGGTGCACGGAGCTTGCATCTGCAAACACAACACACGTGGCCTCAACTGCGAGCAGTGTCAGGATTT CTATCGTGACCTGCCCTGGCGTCCGGCTGAGGACGGCCATAGTCATGCCTGTAGGAAGTGTGAGTGCCAT GGGCACACCCACAGCTGCCACTTCGACATGGCCGTATACCTGGCATCTGGCAATGTGAGTGGAGGTGTGT GTGATGGATGTCAGCATAACACAGCTGGGCGCCACTGTGAGCTCTGTCGGCCCTTCTTCTACCGTGACCC AACCAAGGACCTGCGGGATCCGGCTGTGTGCCGCTCCTGTGATTGTGACCCCATGGGTTCTCAAGACGGT GGTCGCTGTGATTCCCATGATGACCCTGCACTGGGACTGGTCTCCGGCCAGTGTCGCTGCAAAGAACATG TGGTGGGCACTCGCTGCCAGCAATGCCGTGATGGCTTCTTTGGGCTCAGCATCAGTGACCGTCTGGGCTG CCGGCGATGTCAATGTAATGCACGGGGCACAGTGCCTGGGAGCACTCCTTGTGACCCCAACAGTGGATCC TGTTACTGCAAACGTCTAGTGACTGGACGTGGATGTGACCGCTGCCTGCCTGGCCACTGGGGCCTGAGCC ACGACCTGCTCGGCTGCCGCCCCTGTGACTGCGACGTGGGTGGTGCTTTGGATCCCCAGTGTGATGAGGG CACAGGTCAATGCCACTGCCGCCAGCACATGGTTGGGCGACGCTGTGAGCAGGTGCAACCTGGCTACTTC CGGCCCTTCCTGGACCACCTAATTTGGGAGGCTGAGGACACCCGAGGGCAGGTGCTCGATGTGGTGGAGC GCCTGGTGACCCCCGGGGAAACTCCATCCTGGACTGGCTCAGGCTTCGTGCGGCTACAGGAAGGTCAGAC CCTGGAGTTCCTGGTGGCCTCTGTGCCGAAGGCTATGGACTATGACCTGCTGCTGCGCTTAGAGCCCCAG GTCCCTGAGCAATGGGCAGAGTTGGAACTGATTGTGCAGCGTCCAGGGCCTGTGCCTGCCCACAGCCTGT GTGGGCATTTGGTGCCCAAGGATGATCGCATCCAAGGGACTCTGCAACCACATGCCAGGTACTTGATATT TCCTAATCCTGTCTGCCTTGAGCCTGGTATCTCCTACAAGCTGCATCTGAAGCTGGTACGGACAGGGGGA AGTGCCCAGCCTGAGACTCCCTACTCTGGACCTGGCCTGCTCATTGACTCGCTGGTGCTGCTGCCCCGTG TCCTGGTGCTAGAGATGTTTAGTGGGGGTGATGCTGCTGCCCTGGAGCGCCAGGCCACCTTTGAACGCTA CCAATGCCATGAGGAGGGTCTGGTGCCCAGCAAGACTTCTCCCTCTGAGGCCTGCGCACCCCTCCTCATC AGCCTGTCCACCCTCATCTACAATGGTGCCCTGCCATGTCAGTGCAACCCTCAAGGTTCACTGAGTTCTG AGTGCAACCCTCATGGTGGTCAGTGCCTGTGCAAGCCTGGAGTGGTTGGGCGCCGCTGTGACCTCTGTGC CCCTGGCTACTATGGCTTTGGCCCCACAGGCTGTCAAGCCTGCCAGTGCAGCCACGAGGGGGCACTCAGC AGTCTCTGTGAAAAGACCAGTGGGCAATGTCTCTGTCGAACTGGTGCCTTTGGGCTTCGCTGTGACCGCT GCCAGCGTGGCCAGTGGGGATTCCCTAGCTGCCGGCCATGTGTCTGCAATGGGCATGCAGATGAGTGCAA CACCCACACAGGCGCTTGCCTGGGCTGCCGTGATCACACAGGGGGTGAGCACTGTGAAAGGTGCATTGCT GGTTTCCACGGGGACCCACGGCTGCCATATGGGGGCCAGTGCCGGCCCTGTCCCTGTCCTGAAGGCCCTG GGAGCCAACGGCACTTTGCTACTTCTTGCCACCAGGATGAATATTCCCAGCAGATTGTGTGCCACTGCCG GGCAGGCTATACGGGGCTGCGATGTGAAGCTTGTGCCCCTGGGCACTTTGGGGACCCATCAAGGCCAGGT GGCCGGTGCCAACTGTGTGAGTGCAGTGGGAACATTGACCCAATGGATCCTGATGCCTGTGACCCCCACA CGGGGCAATGCCTGCGCTGTTTACACCACACAGAGGGTCCACACTGTGCCCACTGCAAGCCTGGCTTCCA TGGGCAGGCTGCCCGACAGAGCTGTCACCGCTGCACATGCAACCTGCTGGGCACAAATCCGCAGCAGTGC CCATCTCCTGACCAGTGCCACTGTGATCCAAGCAGTGGGCAGTGCCCATGCCTCCCCAATGTCCAGGGCC CTAGCTGTGACCGCTGTGCCCCCAACTTCTGGAACCTCACCAGTGGCCATGGTTGCCAGCCTTGTGCCTG CCACCCAAGCCGGGCCAGAGGCCCCACCTGCAACGAGTTCACAGGGCAGTGCCACTGCCGTGCCGGCTTT GGAGGGCGGACTTGTTCTGAGTGCCAAGAGCTCCACTGGGGAGACCCTGGGTTGCAGTGCCATGCCTGTG ATTGTGACTCTCGTGGAATAGATACACCTCAGTGTCACCGCTTCACAGGTCACTGCAGCTGCCGCCCAGG GGTGTCTGGTGTGCGCTGTGACCAGTGTGCCCGTGGCTTCTCAGGAATCTTTCCTGCCTGCCATCCCTGC CATGCATGCTTCGGGGATTGGGACCGAGTGGTGCAGGACTTGGCAGCCCGTACACAGCGCCTAGAGCAGC GGGCGCAGGAGTTGCAACAGACGGGTGTGCTGGGTGCCTTTGAGAGCAGCTTCTGGCACATGCAGGAGAA GCTGGGCATTGTGCAGGGCATCGTAGGTGCCCGCAACACCTCAGCCGCCTCCACTGCACAGCTTGTGGAG GCCACAGAGGAGCTGCGGCGTGAAATTGGGGAGGCCACTGAGCACCTGACTCAGCTCGAGGCAGACCTGA CAGATGTGCAAGATGAGAACTTCAATGCCAACCATGCACTAAGTGGTCTGGAGCGAGATAGGCTTGCACT TAATCTCACACTGCGGCAGCTCGACCAGCATCTTGACTTGCTCAAACATTCAAACTTCCTGGGTGCCTAT GACAGCATCCGGCATGCCCATAGCCAGTCTGCAGAGGCAGAACGTCGTGCCAATACCTCAGCCCTGGCAG TACCTAGCCCTGTGAGCAACTCGGCAAGTGCTCGGCATCGGACAGAGGCACTGATGGATGCTCAGAAGGA GGACTTCAACAGCAAACACATGGCCAACCAGCGGGCACTTGGCAAGCTCTCTGCCCATACCCACACCCTG AGCCTGACAGACATAAATGAGCTGGTGTGTGGGGCACCAGGGGATGCACCCTGTGCTACAAGCCCTTGTG GGGGTGCCGGCTGTCGAGATGAGGATGGGCAGCCGCGCTGTGGGGGCCTCAGCTGCAATGGGGCAGCGGC TACAGCAGACCTAGCACTGGGCCGGGCCCGGCACACACAGGCAGAGCTGCAGCGGGCACTGGCAGAAGGT GGTAGCATCCTCAGCAGAGTGGCTGAGACTCGTCGGCAGGCAAGCGAGGCACAGCAGCGGGCCCAGGCAG CCCTGGACAAGGCTAATGCTTCCAGGGGACAGGTGGAACAGGCCAACCAGGAACTTCAAGAACTTATCCA GAGTGTGAAGGACTTCCTCAACCAGGAGGGGGCTGATCCTGATAGCATTGAAATGGTGGCCACACGGGTG CTAGAGCTCTCCATCCCAGCTTCAGCTGAGCAGATCCAGCACCTGGCGGGTGCGATTGCAGAGCGAGTCC GGAGCCTGGCAGATGTGGATGCGATCCTGGCACGTACTGTAGGAGATGTGCGTCGTGCCGAGCAGCTACT GCAGGATGCACGGCGGGCAAGGAGCTGGGCTGAGGATGAGAAACAGAAGGCAGAGACAGTACAGGCAGCA CTGGAGGAGGCCCAGCGGGCACAGGGTATTGCCCAGGGTGCCATCCGGGGGGCAGTGGCTGACACACGGG ACACAGAGCAGACCCTGTACCAGGTACAGGAGAGGATGGCAGGTGCAGAGCGGGCACTGAGCTCTGCAGG TGAAAGGGCTCGGCAGTTGGATGCTCTCCTGGAGGCTCTGAAATTGAAACGGGCAGGAAATAGTCTGGCA GCCTCTACAGCAGAAGAAACGGCAGGCAGTGCCCAGGGTCGTGCCCAGGAGGCTGAGCAGCTGCTACGCG GTCCTCTGGGTGATCAGTACCAGACGGTGAAGGCCCTAGCTGAGCGCAAGGCCCAAGGTGTGCTGGCTGC ACAGGCAAGGGCAGAACAACTGCGGGATGAGGCTCGGGACCTGTTGCAAGCCGCTCAGGACAAGCTGCAG CGGCTACAGGAATTGGAAGGCACCTATGAGGAAAATGAGCGGGCACTGGAGAGTAAGGCAGCCCAGTTGG ACGGGTTGGAGGCCAGGATGCGCAGCGTGCTTCAAGCCATCAACTTGCAGGTGCAGATCTACAACACCTG CCAGTGA    Download   Select all
CCDS ID	CCDS2789.1

Protein Information

      

Protein ID	NP_002283.3
Protein Name	Laminin, beta 2 (laminin S)
Molecular Wt. (Da)	192452
Protein Sequence	>3913 MELTSRERGRGQPLPWELRLGLLLSVLAATLAQAPAPDVPGCSRGSCYPATGDLLVGRADRLTA SSTCGLNGPQPYCIVSHLQDEKKCFLCDSRRPFSARDNPHSHRIQNVVTSFAPQRRAAWWQSEN GIPAVTIQLDLEAEFHFTHLIMTFKTFRPAAMLVERSADFGRTWHVYRYFSYDCGADFPGVPLA PPRHWDDVVCESRYSEIEPSTEGEVIYRVLDPAIPIPDPYSSRIQNLLKITNLRVNLTRLHTLG DNLLDPRREIREKYYYALYELVVRGNCFCYGHASECAPAPGAPAHAEGMVHGACICKHNTRGLN CEQCQDFYRDLPWRPAEDGHSHACRKCECHGHTHSCHFDMAVYLASGNVSGGVCDGCQHNTAGR HCELCRPFFYRDPTKDLRDPAVCRSCDCDPMGSQDGGRCDSHDDPALGLVSGQCRCKEHVVGTR CQQCRDGFFGLSISDRLGCRRCQCNARGTVPGSTPCDPNSGSCYCKRLVTGRGCDRCLPGHWGL SHDLLGCRPCDCDVGGALDPQCDEGTGQCHCRQHMVGRRCEQVQPGYFRPFLDHLIWEAEDTRG QVLDVVERLVTPGETPSWTGSGFVRLQEGQTLEFLVASVPKAMDYDLLLRLEPQVPEQWAELEL IVQRPGPVPAHSLCGHLVPKDDRIQGTLQPHARYLIFPNPVCLEPGISYKLHLKLVRTGGSAQP ETPYSGPGLLIDSLVLLPRVLVLEMFSGGDAAALERQATFERYQCHEEGLVPSKTSPSEACAPL LISLSTLIYNGALPCQCNPQGSLSSECNPHGGQCLCKPGVVGRRCDLCAPGYYGFGPTGCQACQ CSHEGALSSLCEKTSGQCLCRTGAFGLRCDRCQRGQWGFPSCRPCVCNGHADECNTHTGACLGC RDHTGGEHCERCIAGFHGDPRLPYGGQCRPCPCPEGPGSQRHFATSCHQDEYSQQIVCHCRAGY TGLRCEACAPGHFGDPSRPGGRCQLCECSGNIDPMDPDACDPHTGQCLRCLHHTEGPHCAHCKP GFHGQAARQSCHRCTCNLLGTNPQQCPSPDQCHCDPSSGQCPCLPNVQGPSCDRCAPNFWNLTS GHGCQPCACHPSRARGPTCNEFTGQCHCRAGFGGRTCSECQELHWGDPGLQCHACDCDSRGIDT PQCHRFTGHCSCRPGVSGVRCDQCARGFSGIFPACHPCHACFGDWDRVVQDLAARTQRLEQRAQ ELQQTGVLGAFESSFWHMQEKLGIVQGIVGARNTSAASTAQLVEATEELRREIGEATEHLTQLE ADLTDVQDENFNANHALSGLERDRLALNLTLRQLDQHLDLLKHSNFLGAYDSIRHAHSQSAEAE RRANTSALAVPSPVSNSASARHRTEALMDAQKEDFNSKHMANQRALGKLSAHTHTLSLTDINEL VCGAPGDAPCATSPCGGAGCRDEDGQPRCGGLSCNGAAATADLALGRARHTQAELQRALAEGGS ILSRVAETRRQASEAQQRAQAALDKANASRGQVEQANQELQELIQSVKDFLNQEGADPDSIEMV ATRVLELSIPASAEQIQHLAGAIAERVRSLADVDAILARTVGDVRRAEQLLQDARRARSWAEDE KQKAETVQAALEEAQRAQGIAQGAIRGAVADTRDTEQTLYQVQERMAGAERALSSAGERARQLD ALLEALKLKRAGNSLAASTAEETAGSAQGRAQEAEQLLRGPLGDQYQTVKALAERKAQGVLAAQ ARAEQLRDEARDLLQAAQDKLQRLQELEGTYEENERALESKAAQLDGLEARMRSVLQAINLQVQ IYNTCQ    Download   Select all
Length	1798
Uniprot ID	P04233
Ensembl Protein ID	ENSP00000009530

Post-translational Modification Information (Source : HPRD)

No matching records could be found.

Enzyme Information

No matching records could be found.

PPi Information

(Click to view network : Source STRING)      View   

No matching records from HPRD source could be found.

Pathway Information

                                          

Pathway Name	Pathway ID
Amoebiasis	hsa05146
ECM-receptor interaction	hsa04512
Focal adhesion	hsa04510
Pathways in cancer	hsa05200
PI3K-Akt signaling pathway	hsa04151
Small cell lung cancer	hsa05222
Toxoplasmosis	hsa05145

Structure Information

No matching records could be found.

Domain Information

ID	Location	Description
cd00055	782-829	EGF_Lam
cl22875	782-829	EGF_Lam superfamily
cd00055	521-562	EGF_Lam
cl22875	521-562	EGF_Lam superfamily
cd00055	469-520	EGF_Lam
cl22875	469-520	EGF_Lam superfamily
cd00055	1037-1093	EGF_Lam
cl22875	1037-1093	EGF_Lam superfamily
cd00055	1142-1191	EGF_Lam
cl22875	1142-1191	EGF_Lam superfamily
cd00055	1094-1136	EGF_Lam
cl22875	1094-1136	EGF_Lam superfamily
cd00055	830-873	EGF_Lam
cl22875	830-873	EGF_Lam superfamily
cd00055	409-468	EGF_Lam
cl22875	409-468	EGF_Lam superfamily
cd00055	876-921	EGF_Lam
cl22875	876-921	EGF_Lam superfamily
cd00055	986-1032	EGF_Lam
cl22875	986-1032	EGF_Lam superfamily
cd00055	926-984	EGF_Lam
cl22875	926-984	EGF_Lam superfamily
cd00055	347-399	EGF_Lam
cl22875	347-399	EGF_Lam superfamily
cd00055	283-335	EGF_Lam
cl22875	283-335	EGF_Lam superfamily
pfam00055	47-281	Laminin_N
cl02806	47-281	Laminin_N superfamily
smart00136	41-281	LamNT
smart00180	783-828	EGF_Lam
pfam00053	783-831	Laminin_EGF
pfam00053	1095-1143	Laminin_EGF
pfam00053	1143-1182	Laminin_EGF
smart00180	522-561	EGF_Lam
pfam00053	831-879	Laminin_EGF
pfam00053	1038-1092	Laminin_EGF
smart00180	1143-1187	EGF_Lam
smart00180	1095-1140	EGF_Lam
smart00180	1038-1092	EGF_Lam
pfam00053	410-467	Laminin_EGF
pfam00053	470-524	Laminin_EGF
pfam00053	522-561	Laminin_EGF
smart00180	831-874	EGF_Lam
smart00180	470-513	EGF_Lam
pfam00053	986-1028	Laminin_EGF
pfam00053	877-924	Laminin_EGF
smart00180	410-460	EGF_Lam
smart00180	986-1028	EGF_Lam
pfam00053	953-983	Laminin_EGF
PRK07353	1687-1773	PRK07353
cl21478	1687-1773	Mt_ATP-synt_B superfamily
pfam14346	1443-1517	DUF4398
cl20518	1443-1517	DUF4398 superfamily
pfam00053	347-398	Laminin_EGF
smart00180	927-976	EGF_Lam
smart00180	877-916	EGF_Lam
TIGR02568	1483-1670	LcrE
cl15454	1483-1670	HrpJ superfamily
pfam05335	1615-1781	DUF745
cl22536	1615-1781	DUF745 superfamily
PRK14475	1680-1792	PRK14475
pfam05960	1479-1752	DUF885
cl19872	1479-1752	DUF885 superfamily
pfam00053	306-338	Laminin_EGF
cd13406	905-984	TNFRSF4
cl22855	905-984	TNFRSF superfamily
pfam09831	1699-1772	DUF2058
cl01201	1699-1772	DUF2058 superfamily
smart00180	347-400	EGF_Lam
cd00176	1504-1754	SPEC
cl02488	1504-1754	SPEC superfamily
PRK14475	1603-1702	PRK14475
cl21478	1603-1702	Mt_ATP-synt_B superfamily
TIGR02473	1709-1772	flagell_FliJ
cl21477	1709-1772	FliJ superfamily
cd07596	1637-1797	BAR_SNX
cl12013	1637-1797	BAR superfamily
pfam05130	1661-1795	FlgN
cl09176	1661-1795	FlgN superfamily
smart00283	1445-1701	MA
pfam13514	1202-1789	AAA_27
PRK02224	1462-1781	PRK02224
pfam12128	1203-1756	DUF3584
COG1196	1202-1798	Smc
pfam12128	1199-1767	DUF3584
COG1196	1447-1792	Smc
TIGR02168	1201-1787	SMC_prok_B
COG4372	1561-1792	COG4372
TIGR02168	1201-1793	SMC_prok_B
COG1196	1445-1767	Smc
PRK04863	1446-1793	mukB
pfam01576	1462-1782	Myosin_tail_1
TIGR02169	1453-1786	SMC_prok_A
TIGR00618	1210-1793	sbcc
pfam13514	1252-1788	AAA_27
COG0419	1452-1795	SbcC
PTZ00121	1455-1772	PTZ00121
TIGR02169	1460-1754	SMC_prok_A
pfam05701	1439-1787	WEMBL
COG5281	1452-1788	COG5281
pfam01576	1450-1782	Myosin_tail_1
TIGR02168	1452-1788	SMC_prok_B
PRK02224	1445-1787	PRK02224
COG2268	1460-1712	YqiK
PRK04863	1452-1773	mukB
TIGR02168	1447-1776	SMC_prok_B
COG1196	1465-1785	Smc
TIGR02680	1459-1786	TIGR02680
PTZ00121	1475-1769	PTZ00121
pfam13514	1194-1794	AAA_27
COG1538	1492-1792	TolC
pfam01576	1456-1792	Myosin_tail_1
PTZ00121	1460-1772	PTZ00121
COG0840	1446-1703	Tar
TIGR02680	1260-1749	TIGR02680
COG3206	1559-1796	GumC
COG4942	1536-1781	EnvC
PRK02224	1574-1788	PRK02224
TIGR02680	1425-1773	TIGR02680
COG2268	1580-1776	YqiK
COG4372	1462-1705	COG4372
TIGR02680	1202-1792	TIGR02680
TIGR02680	1203-1782	TIGR02680
COG3170	1339-1760	FimV
PTZ00121	1460-1782	PTZ00121
pfam10174	1443-1788	Cast
COG0419	1473-1779	SbcC
TIGR02169	1519-1787	SMC_prok_A
COG3096	1453-1787	MukB
pfam13514	1546-1778	AAA_27
COG4942	1453-1695	EnvC
pfam12795	1574-1772	MscS_porin
pfam05557	1454-1782	MAD
TIGR02794	1475-1754	tolA_full
COG4372	1460-1651	COG4372
PRK10929	1483-1796	PRK10929
PRK07735	1476-1732	PRK07735
COG3064	1598-1748	TolA
COG1842	1493-1722	PspA
TIGR02680	1198-1786	TIGR02680
TIGR02169	1561-1793	SMC_prok_A
pfam07111	1561-1777	HCR
TIGR02169	1461-1787	SMC_prok_A
COG4942	1536-1782	EnvC
PRK04863	1579-1782	mukB
TIGR02302	1487-1759	aProt_lowcomp
pfam12128	1443-1793	DUF3584
pfam01576	1446-1782	Myosin_tail_1
TIGR00618	1489-1788	sbcc
pfam06008	1456-1681	Laminin_I
pfam15070	1488-1779	GOLGA2L5
pfam04012	1449-1680	PspA_IM30
pfam04012	1594-1781	PspA_IM30
pfam05701	1584-1782	WEMBL
TIGR03185	1451-1793	DNA_S_dndD
pfam06008	1559-1779	Laminin_I
COG2268	1459-1792	YqiK
COG3096	1585-1791	MukB
PTZ00121	1460-1722	PTZ00121
COG4372	1456-1730	COG4372
pfam09726	1332-1722	Macoilin
pfam13868	1455-1775	Trichoplein
COG3064	1569-1771	TolA
pfam07111	1457-1752	HCR
COG4942	1541-1751	EnvC
PTZ00121	1462-1769	PTZ00121
TIGR02168	1561-1792	SMC_prok_B
COG3883	1483-1715	CwlO1
PRK12472	1603-1747	PRK12472
PRK02224	1263-1703	PRK02224
TIGR02917	1444-1774	PEP_TPR_lipo
PRK10246	1197-1762	PRK10246
pfam04012	1558-1754	PspA_IM30
TIGR02971	1452-1718	heterocyst_DevB
pfam05622	1443-1792	HOOK
TIGR01843	1533-1783	type_I_hlyD
pfam05557	1461-1795	MAD
pfam00769	1636-1772	ERM
TIGR02794	1603-1772	tolA_full
COG3206	1445-1665	GumC
pfam10174	1451-1766	Cast
pfam00529	1636-1783	HlyD
PRK10246	1450-1771	PRK10246
COG0711	1476-1615	AtpF
COG3096	1492-1783	MukB
pfam07111	1445-1786	HCR
COG0419	1550-1798	SbcC
TIGR02302	1490-1755	aProt_lowcomp
PRK12472	1571-1698	PRK12472
TIGR03348	1555-1732	VI_IcmF
TIGR04510	1564-1753	mod_pep_cyc
PRK04863	1476-1777	mukB
COG3206	1457-1728	GumC
COG3599	1486-1638	DivIVA
COG0711	1690-1773	AtpF
pfam05262	1559-1740	Borrelia_P83
pfam13868	1477-1793	Trichoplein
pfam15558	1581-1787	DUF4659
COG3599	1568-1751	DivIVA
PRK14473	1453-1541	PRK14473
TIGR02169	1460-1731	SMC_prok_A
COG1842	1646-1781	PspA
pfam06008	1504-1753	Laminin_I
COG1842	1607-1792	PspA
COG1340	1457-1761	COG1340
pfam12795	1459-1701	MscS_porin
COG1538	1444-1688	TolC
COG3064	1454-1691	TolA
pfam06008	1549-1762	Laminin_I
TIGR02169	1624-1781	SMC_prok_A
COG4717	1456-1788	YhaN
PRK09510	1582-1778	tolA
PRK07735	1456-1725	PRK07735
PRK04863	1449-1739	mukB
COG0845	1536-1793	AcrA
PRK12402	1533-1681	PRK12402
pfam00769	1581-1769	ERM
pfam00261	1579-1782	Tropomyosin
pfam07888	1497-1780	CALCOCO1
TIGR02977	1559-1756	phageshock_pspA
pfam00529	1443-1615	HlyD
pfam04632	1528-1756	FUSC
TIGR02971	1646-1793	heterocyst_DevB
PRK06669	1462-1563	fliH
PRK11281	1548-1791	PRK11281
PRK07352	1610-1757	PRK07352
TIGR02169	1460-1740	SMC_prok_A
TIGR01843	1533-1752	type_I_hlyD
TIGR00634	1452-1632	recN
PRK09039	1644-1793	PRK09039
pfam13779	1487-1781	DUF4175
pfam11180	1539-1669	DUF2968
pfam13868	1582-1780	Trichoplein
PRK09510	1580-1742	tolA
COG2909	1460-1773	MalT
pfam00430	1701-1772	ATP-synt_B
pfam00038	1450-1664	Filament
pfam06818	1601-1782	Fez1
COG3264	1608-1742	MscK
COG3264	1460-1593	MscK
COG1538	1555-1750	TolC
COG1570	1623-1791	XseA
PRK15374	1586-1779	PRK15374
pfam00430	1690-1768	ATP-synt_B
COG3264	1633-1786	MscK
PRK04863	1187-1681	mukB
COG3264	1440-1643	MscK
pfam12795	1460-1622	MscS_porin
pfam11180	1445-1525	DUF2968
pfam02841	1711-1769	GBP_C
pfam12795	1452-1526	MscS_porin
PRK05035	1584-1772	PRK05035
pfam11180	1455-1519	DUF2968
pfam13851	1727-1789	GAS
pfam00430	1627-1750	ATP-synt_B
pfam06818	1457-1612	Fez1
pfam04111	1263-1335	APG6

Ontology Information

   

HPRD ID	4686
Molecular Class	Extracellular matrix protein
Molecular Function	Protein binding (GO:0005515)
Biological Process	Cell cycle (GO:0007049)

SNP Information

View SNP Geneview Report   

Drug Information

No matching records could be found.

External Links

                                 

ArrayExpress	GO
ICGC	GO
Cancer3D	GO
COSMIC	GO
NCG	GO
TSGene	GO
Tumor Gene Family of Databases	GO
CCDB	GO
G2SBC	GO
Osteosarcoma Database	GO
RCDB	GO