Search results:
General Information
| Gene_Symbol | Gene_ID | Gene_Name | Chromosome | Alias |
|---|---|---|---|---|
| LGALS4 | 3960 | lectin, galactoside-binding, soluble, 4 | 19 | GAL4 |
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 23378274 | 2013 | Cell line : HT 29 Source : - Sample Type : Tissue from adenoma, carcinoma and ulcerative colitis No. of Sample : - Stage : - | Immunohistochemistry, RT-PCR, qPCR array, Western blotting, and immunofluorescence assays | Down-regulation | - | Down-regulation of galectin-4 elicits tumor promotion in vitro and in vivo through activation of IL-6/NF-?B/STAT3 signaling. |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | Lectins, galactoside-binding |
| Description | The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. The expression of this gene is restricted to small intestine, colon, and rectum, and it is underexpressed in colorectal cancer. [provided by RefSeq, Jul 2008] |
| Chromosome | 19 |
| Location | 19q13.2 |
| Start | 39292311 |
| End | 39303740 |
| Strand | - |
| Gene Sequence | Download Select all |
| Length | 11430 |
| OMIM ID | 602518 |
| HGNC ID | HGNC:6565 |
| Unigene ID | Hs.5302 |
| Ensembl ID | ENSG00000171747 |
| PharmGKB ID | PA30342 |
mRNA Information
| mRNA ID | XM_011526974.1 |
|---|---|
| Exon | join(1..703,1026..1114,6950..7084,9650..9676,9765..9803, 9994..10023,11141..11229,11388..11553,11635..11874) | mRNA Sequence | Download Select all |
| Length | 1518 |
Protein Information
| Protein ID | XP_011525276.1 |
|---|---|
| Protein Name | lectin, galactoside-binding, soluble, 4 |
| Molecular Wt. (Da) | 9432 |
| Protein Sequence | Download Select all |
| Length | 192 |
| Uniprot ID | P36402 |
| Ensembl Protein ID | ENSP00000340347 |
Post-translational Modification Information (Source : HPRD)
No matching records could be found.
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
| Interactant Gene ID (Source: HPRD) | Gene Symbol | HPRD ID | Ref Seq ID | Technique | References |
|---|---|---|---|---|---|
| 10094 | ARPC3 | 9175 | NP_005710.1 | yeast 2-hybrid | 16169070 |
| 22800 | RRAS2 | 2518 | NP_036382.2 | yeast 2-hybrid | 16169070 |
| 57670 | KIAA1549 | 13873 | NP_001158137.1 | yeast 2-hybrid | 16169070 |
Pathway Information
No matching records could be found.
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| cd00070 | 18-147 | GLECT |
| cl00071 | 18-147 | GLECT superfamily |
| cd00070 | 193-322 | GLECT |
| cl00071 | 193-322 | GLECT superfamily |
| smart00908 | 24-148 | Gal-bind_lectin |
| smart00908 | 199-322 | Gal-bind_lectin |
| pfam00337 | 18-149 | Gal-bind_lectin |
| pfam00337 | 193-323 | Gal-bind_lectin |
| smart00276 | 197-323 | GLECT |
| smart00276 | 19-149 | GLECT |
Ontology Information
| HPRD ID | 1798 |
|---|---|
| Molecular Class | Adhesion molecule |
| Molecular Function | Transcription factor activity (GO:0003700) |
| Biological Process | Regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism (GO:0019219) |
Drug Information
No matching records could be found.