Search results:
General Information
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 23585469 | 2014 | Cell line : SW48 Source : - Sample Type : Human CRC tumor and mice CRC tumor No. of Sample : 650 Stage : - | Immunostaining,Promoter methylation | Down-regulation | - | LIMK2 expression and activity progressively decrease with advancing stage. |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | - |
| Description | There are approximately 40 known eukaryotic LIM proteins, so named for the LIM domains they contain. LIM domains are highly conserved cysteine-rich structures containing 2 zinc fingers. Although zinc fingers usually function by binding to DNA or RNA, the LIM motif probably mediates protein-protein interactions. LIM kinase-1 and LIM kinase-2 belong to a small subfamily with a unique combination of 2 N-terminal LIM motifs and a C-terminal protein kinase domain. The protein encoded by this gene is phosphorylated and activated by ROCK, a downstream effector of Rho, and the encoded protein, in turn, phosphorylates cofilin, inhibiting its actin-depolymerizing activity. It is thought that this pathway contributes to Rho-induced reorganization of the actin cytoskeleton. At least three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
| Chromosome | 22 |
| Location | 22q12 |
| Start | 31608225 |
| End | 31676066 |
| Strand | + |
| Gene Sequence | Download Select all |
| Length | 67842 |
| OMIM ID | 601988 |
| HGNC ID | HGNC:6614 |
| Unigene ID | Hs.474596 |
| Ensembl ID | ENSG00000182541 |
| PharmGKB ID | PA30387 |
mRNA Information
| mRNA ID | NM_005569.3 |
|---|---|
| Exon | join(1..161,13457..13556,46028..46163,46858..46967, 47626..47814,49871..49976,50332..50528,53683..53869, 54721..54807,55513..55644,55881..55937,58873..58938, 60267..60441,61189..61244,62888..63045,66034..67817) | mRNA Sequence | Download Select all |
| Length | 3701 |
Protein Information
| Protein ID | NP_005560.1 |
|---|---|
| Protein Name | LIM domain kinase 2 |
| Molecular Wt. (Da) | 72101 |
| Protein Sequence | Download Select all |
| Length | 638 |
| Uniprot ID | O43680 |
| Ensembl Protein ID | ENSP00000237316 |
Post-translational Modification Information (Source : HPRD)
| Residue | Type | site |
|---|---|---|
| T | Phosphorylation | 505 |
| T | Phosphorylation | 526 |
| T | Phosphorylation | 505 |
| T | Phosphorylation | 505 |
| T | Phosphorylation | 526 |
| T | Phosphorylation | 505 |
| S | Phosphorylation | 266 |
| S | Phosphorylation | 272 |
| S | Phosphorylation | 277 |
| S | Phosphorylation | 287 |
| S | Phosphorylation | 293 |
| S | Phosphorylation | 298 |
| S | Phosphorylation | 266 |
| S | Phosphorylation | 272 |
| S | Phosphorylation | 277 |
| S | Phosphorylation | 266 |
| S | Phosphorylation | 272 |
| S | Phosphorylation | 277 |
| S | Phosphorylation | 268 |
| S | Phosphorylation | 289 |
| S | Phosphorylation | 268 |
| S | Phosphorylation | 268 |
| T | Phosphorylation | 189 |
| T | Phosphorylation | 210 |
| T | Phosphorylation | 189 |
| T | Phosphorylation | 189 |
| S | Phosphorylation | 170 |
| S | Phosphorylation | 191 |
| S | Phosphorylation | 170 |
| S | Phosphorylation | 170 |
| S | Phosphorylation | 276 |
| S | Phosphorylation | 297 |
| S | Phosphorylation | 276 |
| S | Phosphorylation | 276 |
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
| Interactant Gene ID (Source: HPRD) | Gene Symbol | HPRD ID | Ref Seq ID | Technique | References |
|---|---|---|---|---|---|
| 1072 | CFL1 | 3261 | NP_005498.1 | in vitro;in vivo | 9 655 398 114 185 990 000 000 000 000 000 |
| 2934 | GSN | 674 | NP_000168.1 | in vitro | 11171090 |
| 3984 | LIMK1 | 3210 | NP_002305.1 | in vitro;in vivo | 8980133 |
Pathway Information
| Pathway Name | Pathway ID |
|---|---|
| Axon guidance | hsa04360 |
| Fc gamma R-mediated phagocytosis | hsa04666 |
| Regulation of actin cytoskeleton | hsa04810 |
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| cd14222 | 337-608 | STKc_LIMK2 |
| cl21453 | 337-608 | PKc_like superfamily |
| cd09465 | 67-125 | LIM2_LIMK2 |
| cl02475 | 67-125 | LIM superfamily |
| cd09463 | Dec-65 | LIM1_LIMK2 |
| cl02475 | Dec-65 | LIM superfamily |
| cd14154 | 337-608 | STKc_LIMK |
| cd14221 | 337-608 | STKc_LIMK1 |
| cd14065 | 337-599 | PKc_LIMK_like |
| cd14155 | 337-604 | PKc_TESK |
| cd13999 | 337-601 | STKc_MAP3K-like |
| cd14156 | 337-605 | PKc_LIMK_like_unk |
| cd00192 | 335-602 | PTKc |
| cd00180 | 337-539 | PKc |
| cd06606 | 330-601 | STKc_MAPKKK |
| cd05117 | 334-536 | STKc_CAMK |
| cd08215 | 335-538 | STKc_Nek |
| cd14014 | 335-593 | STKc_PknB_like |
| cd05122 | 335-538 | PKc_STE |
| cd14007 | 334-592 | STKc_Aurora |
| cd06614 | 335-540 | STKc_PAK |
| cd14066 | 337-604 | STKc_IRAK |
| cd05123 | 337-540 | STKc_AGC |
| cd06612 | 335-601 | STKc_MST1_2 |
| cd14003 | 334-536 | STKc_AMPK-like |
| cd05038 | 337-604 | PTKc_Jak_rpt2 |
| cd05039 | 330-604 | PTKc_Csk_like |
| cd05033 | 335-604 | PTKc_EphR |
| cd06611 | 332-539 | STKc_SLK_like |
| cd14059 | 375-594 | STKc_MAP3K12_13 |
| cd06623 | 336-538 | PKc_MAPKK_plant_like |
| cd05085 | 334-603 | PTKc_Fer |
| cd05041 | 335-600 | PTKc_Fes_like |
| cd06627 | 334-597 | STKc_Cdc7_like |
| cd05084 | 334-597 | PTKc_Fes |
| cd08529 | 330-538 | STKc_FA2-like |
| cd06605 | 336-597 | PKc_MAPKK |
| cd13996 | 335-540 | STKc_EIF2AK |
| cd13978 | 337-542 | STKc_RIP |
| cd14058 | 337-598 | STKc_TAK1 |
| cd06610 | 335-597 | STKc_OSR1_SPAK |
| cd14009 | 337-538 | STKc_ATG1_ULK_like |
| cd05032 | 325-597 | PTKc_InsR_like |
| cd05065 | 335-604 | PTKc_EphR_B |
| cd05034 | 337-602 | PTKc_Src_like |
| cd05066 | 335-604 | PTKc_EphR_A |
| cd05059 | 328-600 | PTKc_Tec_like |
| cd06644 | 332-539 | STKc_STK10 |
| cd09364 | Dec-65 | LIM1_LIMK |
| cd05063 | 328-604 | PTKc_EphR_A2 |
| cd05052 | 337-604 | PTKc_Abl |
| cd06629 | 332-597 | STKc_Bck1_like |
| cd05035 | 331-604 | PTKc_TAM |
| cd14099 | 334-536 | STKc_PLK |
| cd06613 | 337-538 | STKc_MAP4K3_like |
| cd05148 | 334-603 | PTKc_Srm_Brk |
| cd05082 | 330-602 | PTKc_Csk |
| cd05045 | 330-604 | PTKc_RET |
| cd06632 | 334-597 | STKc_MEKK1_plant |
| cd06625 | 334-540 | STKc_MEKK3_like |
| cd14064 | 337-540 | PKc_TNNI3K |
| cd05112 | 328-597 | PTKc_Itk |
| cd05053 | 330-604 | PTKc_FGFR |
| cd14205 | 326-597 | PTKc_Jak2_rpt2 |
| cd14060 | 338-604 | STKc_MLTK |
| cd05051 | 335-601 | PTKc_DDR |
| cd06643 | 332-539 | STKc_SLK |
| cd05083 | 331-602 | PTKc_Chk |
| cd14027 | 337-601 | STKc_RIP1 |
| cd05068 | 337-602 | PTKc_Frk_like |
| cd14081 | 334-536 | STKc_BRSK1_2 |
| cd07829 | 335-540 | STKc_CDK_like |
| cd06609 | 335-597 | STKc_MST3_like |
| cd05579 | 339-540 | STKc_MAST_like |
| cd14061 | 336-604 | STKc_MLK |
| cd05067 | 335-603 | PTKc_Lck_Blk |
| cd14158 | 334-540 | STKc_IRAK4 |
| cd13992 | 367-598 | PK_GC |
| cd14147 | 335-604 | STKc_MLK3 |
| cd14062 | 337-602 | STKc_Raf |
| cd14203 | 337-602 | PTKc_Src_Fyn_like |
| cd08217 | 335-539 | STKc_Nek2 |
| cd05074 | 334-604 | PTKc_Tyro3 |
| cd05572 | 337-551 | STKc_cGK |
| cd09365 | 72-125 | LIM2_LIMK |
| cd13983 | 335-540 | STKc_WNK |
| cd05075 | 334-605 | PTKc_Axl |
| cd06628 | 332-549 | STKc_Byr2_like |
| cd05580 | 330-540 | STKc_PKA_like |
| cd05073 | 337-602 | PTKc_Hck |
| cd14148 | 336-604 | STKc_MLK2 |
| cd05081 | 336-604 | PTKc_Jak3_rpt2 |
| cd06608 | 334-534 | STKc_myosinIII_N_like |
| cd05099 | 331-618 | PTKc_FGFR4 |
| cd05047 | 335-597 | PTKc_Tie |
| cd14145 | 330-604 | STKc_MLK1 |
| cd06647 | 335-540 | STKc_PAK_I |
| cd05058 | 335-605 | PTKc_Met_Ron |
| cd05072 | 337-603 | PTKc_Lyn |
| cd08220 | 336-539 | STKc_Nek8 |
| cd14146 | 336-604 | STKc_MLK4 |
| cd05060 | 337-601 | PTKc_Syk_like |
| cd14095 | 334-537 | STKc_DCKL |
| cd07832 | 337-540 | STKc_CCRK |
| cd06917 | 335-547 | STKc_NAK1_like |
| cd05080 | 335-597 | PTKc_Tyk2_rpt2 |
| cd05048 | 334-597 | PTKc_Ror |
| cd14073 | 335-536 | STKc_NUAK |
| cd06648 | 337-540 | STKc_PAK_II |
| cd05079 | 337-604 | PTKc_Jak1_rpt2 |
| cd05089 | 330-597 | PTKc_Tie1 |
| cd14098 | 335-536 | STKc_Rad53_Cds1 |
| cd06640 | 335-580 | STKc_MST4 |
| cd14046 | 335-540 | STKc_EIF2AK4_GCN2_rpt2 |
| cd05044 | 334-603 | PTKc_c-ros |
| cd14002 | 335-542 | STKc_STK36 |
| cd05056 | 330-602 | PTKc_FAK |
| cd05113 | 328-539 | PTKc_Btk_Bmx |
| cd06653 | 328-542 | STKc_MEKK3_like_u1 |
| cd05581 | 330-536 | STKc_PDK1 |
| cd05057 | 325-601 | PTKc_EGFR_like |
| cd06621 | 337-539 | PKc_Pek1_like |
| cd07833 | 335-540 | STKc_CDKL |
| cd05040 | 335-599 | PTKc_Ack_like |
| cd14008 | 337-543 | STKc_LKB1_CaMKK |
| cd14204 | 331-605 | PTKc_Mer |
| cd05061 | 337-594 | PTKc_InsR |
| cd05095 | 331-597 | PTKc_DDR2 |
| cd06641 | 335-597 | STKc_MST3 |
| cd06631 | 334-539 | STKc_YSK4 |
| cd05071 | 337-602 | PTKc_Src |
| cd06655 | 335-540 | STKc_PAK2 |
| cd06626 | 334-540 | STKc_MEKK4 |
| cd05097 | 335-597 | PTKc_DDR_like |
| cd14053 | 335-540 | STKc_ACVR2 |
| cd06654 | 335-540 | STKc_PAK1 |
| cd14072 | 337-536 | STKc_MARK |
| cd06630 | 332-539 | STKc_MEKK1 |
| cd06656 | 335-540 | STKc_PAK3 |
| cd13994 | 337-540 | STKc_HAL4_like |
| cd05043 | 328-597 | PTK_Ryk |
| cd07860 | 335-540 | STKc_CDK2_3 |
| cd05036 | 337-595 | PTKc_ALK_LTK |
| cd14010 | 363-538 | STKc_ULK4 |
| cd05050 | 337-595 | PTKc_Musk |
| cd06639 | 335-599 | STKc_myosinIIIB_N |
| cd14047 | 335-601 | STKc_EIF2AK2_PKR |
| cd06659 | 337-540 | STKc_PAK6 |
| cd06652 | 334-542 | STKc_MEKK2 |
| cd06638 | 335-539 | STKc_myosinIIIA_N |
| cd05055 | 331-597 | PTKc_PDGFR |
| cd08530 | 336-597 | STKc_CNK2-like |
| cd05111 | 324-601 | PTK_HER3 |
| cd14055 | 335-543 | STKc_TGFbR2_like |
| cd14185 | 334-536 | STKc_DCKL3 |
| cd05096 | 356-597 | PTKc_DDR1 |
| cd06642 | 335-597 | STKc_STK25 |
| cd14149 | 337-604 | STKc_C-Raf |
| cd05070 | 337-603 | PTKc_Fyn |
| cd14151 | 334-605 | STKc_B-Raf |
| cd05069 | 337-603 | PTKc_Yes |
| cd05046 | 336-597 | PTK_CCK4 |
| cd14121 | 335-540 | STKc_ULK3 |
| cd14063 | 330-604 | PK_KSR |
| cd14045 | 354-598 | PK_GC_unk |
| cd05573 | 336-540 | STKc_ROCK_NDR_like |
| cd07834 | 336-541 | STKc_MAPK |
| cd05118 | 336-540 | STKc_CMGC |
| cd05098 | 331-606 | PTKc_FGFR1 |
| cd14116 | 334-537 | STKc_Aurora-A |
| cd05049 | 330-539 | PTKc_Trk |
| cd06619 | 330-599 | PKc_MKK5 |
| cd05092 | 337-603 | PTKc_TrkA |
| cd08218 | 337-539 | STKc_Nek1 |
| cd05064 | 336-599 | PTKc_EphR_A10 |
| cd14150 | 337-604 | STKc_A-Raf |
| cd14077 | 330-536 | STKc_Kin1_2 |
| cd14161 | 335-536 | STKc_NUAK2 |
| cd08216 | 336-597 | PK_STRAD |
| cd08222 | 337-539 | STKc_Nek11 |
| cd08224 | 337-538 | STKc_Nek6_7 |
| cd05062 | 373-602 | PTKc_IGF-1R |
| cd06651 | 328-542 | STKc_MEKK3 |
| cd14162 | 334-536 | STKc_TSSK4-like |
| cd14056 | 335-556 | STKc_TGFbR_I |
| cd14071 | 336-536 | STKc_SIK |
| cd05100 | 331-615 | PTKc_FGFR3 |
| cd05612 | 337-540 | STKc_PRKX_like |
| cd07841 | 334-540 | STKc_CDK7 |
| cd06633 | 337-539 | STKc_TAO3 |
| cd14054 | 373-539 | STKc_BMPR2_AMHR2 |
| cd07835 | 335-540 | STKc_CDK1_CdkB_like |
| cd05600 | 337-538 | STKc_Sid2p_like |
| cd13998 | 335-539 | STKc_TGFbR-like |
| cd14012 | 383-601 | PK_eIF2AK_GCN2_rpt1 |
| cd14664 | 337-540 | STK_BAK1_like |
| cd14075 | 332-536 | STKc_NIM1 |
| cd14209 | 336-539 | STKc_PKA |
| cd08221 | 336-540 | STKc_Nek9 |
| cd05595 | 335-540 | STKc_PKB_beta |
| cd07838 | 337-601 | STKc_CDK4_6_like |
| cd14033 | 361-569 | STKc_WNK4 |
| cd05088 | 330-597 | PTKc_Tie2 |
| cd07830 | 335-539 | STKc_MAK_like |
| cd14069 | 334-536 | STKc_Chk1 |
| cd14048 | 335-540 | STKc_EIF2AK3_PERK |
| cd14087 | 336-535 | STKc_PSKH1 |
| cd14663 | 334-536 | STKc_SnRK3 |
| cd14103 | 337-539 | STKc_MLCK |
| cd05603 | 335-540 | STKc_SGK2 |
| cd14190 | 335-535 | STKc_MLCK2 |
| cd05101 | 331-610 | PTKc_FGFR2 |
| cd14137 | 335-592 | STKc_GSK3 |
| cd05578 | 336-540 | STKc_Yank1 |
| cd05593 | 330-540 | STKc_PKB_gamma |
| cd06658 | 337-540 | STKc_PAK5 |
| cd14080 | 334-536 | STKc_TSSK-like |
| cd14184 | 334-535 | STKc_DCKL2 |
| cd05602 | 327-540 | STKc_SGK1 |
| cd07840 | 337-540 | STKc_CDK9_like |
| cd13985 | 336-536 | STKc_GAK_like |
| cd06657 | 337-540 | STKc_PAK4 |
| cd05604 | 335-540 | STKc_SGK3 |
| cd14078 | 335-536 | STKc_MELK |
| cd14006 | 337-535 | STKc_MLCK-like |
| cd05571 | 335-540 | STKc_PKB |
| cd14079 | 334-536 | STKc_AMPK_alpha |
| cd14052 | 335-543 | PTKc_Wee1_fungi |
| cd08225 | 335-539 | STKc_Nek5 |
| cd08528 | 335-539 | STKc_Nek10 |
| cd06607 | 337-539 | STKc_TAO |
| cd14167 | 335-537 | STKc_CaMKI_alpha |
| cd05575 | 336-540 | STKc_SGK |
| cd05614 | 335-540 | STKc_MSK2_N |
| cd05611 | 339-540 | STKc_Rim15_like |
| cd05114 | 328-539 | PTKc_Tec_Rlk |
| cd14084 | 336-536 | STKc_Chk2 |
| cd05116 | 337-598 | PTKc_Syk |
| cd05619 | 330-563 | STKc_nPKC_theta |
| cd14097 | 334-536 | STKc_STK33 |
| cd13997 | 337-541 | PKc_Wee1_like |
| cd06650 | 337-617 | PKc_MEK1 |
| cd07836 | 335-540 | STKc_Pho85 |
| cd08219 | 336-539 | STKc_Nek3 |
| cd14083 | 335-537 | STKc_CaMKI |
| cd05570 | 336-542 | STKc_PKC |
| cd08228 | 337-592 | STKc_Nek6 |
| cd05592 | 336-542 | STKc_nPKC_theta_like |
| cd07861 | 330-540 | STKc_CDK1_euk |
| cd14117 | 334-537 | STKc_Aurora-B_like |
| cd14159 | 337-540 | STKc_IRAK1 |
| cd05115 | 337-603 | PTKc_Zap-70 |
| cd09464 | 72-125 | LIM2_LIMK1 |
| cd14193 | 335-535 | STKc_MLCK4 |
| cd14085 | 337-535 | STKc_CaMKIV |
| cd05108 | 324-605 | PTKc_EGFR |
| cd14665 | 337-548 | STKc_SnRK2-3 |
| cd06645 | 337-539 | STKc_MAP4K3 |
| cd05629 | 335-541 | STKc_NDR_like_fungal |
| cd06636 | 335-539 | STKc_MAP4K4_6_N |
| cd06620 | 327-539 | PKc_Byr1_like |
| cd14187 | 332-601 | STKc_PLK1 |
| cd14662 | 337-548 | STKc_SnRK2 |
| cd05620 | 335-542 | STKc_nPKC_delta |
| cd05574 | 335-540 | STKc_phototropin_like |
| cd07846 | 335-597 | STKc_CDKL2_3 |
| cd06646 | 337-597 | STKc_MAP4K5 |
| cd07839 | 335-539 | STKc_CDK5 |
| cd05054 | 334-597 | PTKc_VEGFR |
| cd07866 | 334-540 | STKc_BUR1 |
| cd06615 | 336-547 | PKc_MEK |
| cd14049 | 337-539 | STKc_EIF2AK1_HRI |
| cd08223 | 336-539 | STKc_Nek4 |
| cd14089 | 332-537 | STKc_MAPKAPK |
| cd14144 | 337-539 | STKc_BMPR1 |
| cd14143 | 335-539 | STKc_TGFbR1_ACVR1b_ACVR1c |
| cd14119 | 337-536 | STKc_LKB1 |
| cd05090 | 373-597 | PTKc_Ror1 |
| cd05608 | 336-540 | STKc_GRK1 |
| cd05110 | 324-605 | PTKc_HER4 |
| cd05583 | 336-540 | STKc_MSK_N |
| cd14050 | 335-539 | PKc_Myt1 |
| cd05093 | 337-539 | PTKc_TrkB |
| cd05594 | 330-540 | STKc_PKB_alpha |
| cd05609 | 340-540 | STKc_MAST |
| cd14192 | 333-535 | STKc_MLCK3 |
| cd07865 | 337-538 | STKc_CDK9 |
| cd06617 | 330-599 | PKc_MKK3_6 |
| cd05615 | 336-542 | STKc_cPKC_alpha |
| cd06622 | 337-597 | PKc_PBS2_like |
| cd05094 | 330-539 | PTKc_TrkC |
| cd13979 | 334-536 | STKc_Mos |
| cd14166 | 335-535 | STKc_CaMKI_gamma |
| cd07847 | 337-540 | STKc_CDKL1_4 |
| cd05109 | 324-605 | PTKc_HER2 |
| cd14202 | 335-536 | STKc_ULK1 |
| cd07848 | 336-539 | STKc_CDKL5 |
| cd06618 | 323-597 | PKc_MKK7 |
| cd14194 | 334-535 | STKc_DAPK1 |
| cd14179 | 335-543 | STKc_MSK1_C |
| cd05613 | 335-540 | STKc_MSK1_N |
| cd14142 | 383-539 | STKc_ACVR1_ALK1 |
| cd05616 | 336-543 | STKc_cPKC_beta |
| cd13982 | 376-535 | STKc_IRE1 |
| cd05582 | 336-540 | STKc_RSK_N |
| cd14031 | 337-549 | STKc_WNK3 |
| cd06635 | 337-539 | STKc_TAO1 |
| cd14120 | 337-575 | STKc_ULK1_2-like |
| cd14025 | 335-542 | STKc_RIP4_like |
| cd14076 | 332-536 | STKc_Kin4 |
| cd14074 | 334-536 | STKc_SNRK |
| cd14206 | 337-539 | PTKc_Aatyk3 |
| cd06637 | 335-539 | STKc_TNIK |
| cd08229 | 337-592 | STKc_Nek7 |
| cd14186 | 334-555 | STKc_PLK4 |
| cd14036 | 336-536 | STKc_GAK |
| cd14105 | 334-535 | STKc_DAPK |
| cd14093 | 335-536 | STKc_PhKG |
| cd14152 | 334-604 | STKc_KSR1 |
| cd14042 | 309-597 | PK_GC-A_B |
| cd14044 | 355-605 | PK_GC-C |
| cd09462 | Dec-65 | LIM1_LIMK1 |
| cd14191 | 335-540 | STKc_MLCK1 |
| cd05577 | 337-540 | STKc_GRK |
| cd14201 | 335-566 | STKc_ULK2 |
| cd05042 | 337-473 | PTKc_Aatyk |
| cd13986 | 337-536 | STKc_16 |
| cd07863 | 337-574 | STKc_CDK4 |
| cd14183 | 334-535 | STKc_DCKL1 |
| cd14070 | 334-592 | STKc_HUNK |
| cd06634 | 337-539 | STKc_TAO2 |
| cd13993 | 335-540 | STKc_Pat1_like |
| cd14001 | 364-540 | PKc_TOPK |
| cd14210 | 335-539 | PKc_DYRK |
| cd14169 | 335-537 | STKc_CaMKI_beta |
| cd14188 | 334-536 | STKc_PLK2 |
| cd14057 | 373-594 | PK_ILK |
| cd14038 | 337-540 | STKc_IKK_beta |
| cd06649 | 337-547 | PKc_MEK2 |
| cd14092 | 335-536 | STKc_MSK_C |
| cd14032 | 370-549 | STKc_WNK2_like |
| cd14088 | 334-536 | STKc_CaMK_like |
| cd14096 | 337-536 | STKc_RCK1-like |
| cd14153 | 334-604 | PK_KSR2 |
| cd14180 | 332-543 | STKc_MSK2_C |
| cd13989 | 337-540 | STKc_IKK |
| cd14082 | 335-536 | STKc_PKD |
| cd14141 | 376-545 | STKc_ACVR2a |
| cd14000 | 372-592 | STKc_LRRK |
| cd05091 | 335-597 | PTKc_Ror2 |
| cd14163 | 334-536 | STKc_TSSK3-like |
| cd05587 | 336-542 | STKc_cPKC |
| cd07871 | 337-540 | STKc_PCTAIRE3 |
| cd13987 | 337-591 | STKc_SBK1 |
| cd05627 | 335-540 | STKc_NDR2 |
| cd14106 | 331-535 | STKc_DRAK |
| cd06624 | 336-540 | STKc_ASK |
| cd07831 | 337-540 | STKc_MOK |
| cd14168 | 335-535 | STKc_CaMKI_delta |
| cd05584 | 336-533 | STKc_p70S6K |
| cd05626 | 335-587 | STKc_LATS2 |
| cd14030 | 370-549 | STKc_WNK1 |
| cd07837 | 335-540 | STKc_CdkB_plant |
| cd05585 | 336-540 | STKc_YPK1_like |
| cd06616 | 330-539 | PKc_MKK4 |
| cd07845 | 337-541 | STKc_CDK10 |
| pfam00595 | 152-236 | PDZ |
| cl00117 | 152-236 | PDZ superfamily |
| cd14196 | 334-535 | STKc_DAPK2 |
| cd07843 | 340-540 | STKc_CDC2L1 |
| cd14207 | 334-597 | PTKc_VEGFR1 |
| cd14189 | 334-536 | STKc_PLK3 |
| pfam00412 | Dec-68 | LIM |
| cd14140 | 383-545 | STKc_ACVR2b |
| cd05105 | 348-604 | PTKc_PDGFR_alpha |
| cd14199 | 376-542 | STKc_CaMKK2 |
| cd05102 | 328-597 | PTKc_VEGFR3 |
| cd14195 | 334-535 | STKc_DAPK3 |
| cd07864 | 336-539 | STKc_CDK12 |
| cd14164 | 334-536 | STKc_TSSK6-like |
| cd14118 | 376-543 | STKc_CAMKK |
| cd05589 | 336-540 | STKc_PKN |
| cd05107 | 330-597 | PTKc_PDGFR_beta |
| cd07852 | 337-540 | STKc_MAPK15-like |
| cd05621 | 327-546 | STKc_ROCK2 |
| cd05590 | 335-540 | STKc_nPKC_eta |
| cd07851 | 335-540 | STKc_p38 |
| cd14111 | 338-593 | STKc_SPEG_rpt2 |
| cd07869 | 335-547 | STKc_PFTAIRE1 |
| cd05106 | 334-597 | PTKc_CSF-1R |
| cd14170 | 332-536 | STKc_MAPKAPK2 |
| cd14043 | 367-605 | PK_GC-2D |
| cd14090 | 334-536 | STKc_Mnk |
| cd07872 | 335-539 | STKc_PCTAIRE2 |
| cd14200 | 376-542 | STKc_CaMKK1 |
| cd05622 | 335-546 | STKc_ROCK1 |
| cd05618 | 313-541 | STKc_aPKC_iota |
| cd13968 | 337-471 | PKc_like |
| cd05087 | 337-479 | PTKc_Aatyk1 |
| cd05628 | 335-540 | STKc_NDR1 |
| cd14133 | 335-539 | PKc_DYRK_like |
| cd14172 | 335-536 | STKc_MAPKAPK3 |
| cd14026 | 337-542 | STKc_RIP2 |
| smart00132 | Nov-63 | LIM |
| cd14091 | 335-536 | STKc_RSK_C |
| cd07862 | 337-539 | STKc_CDK6 |
| cd14004 | 335-540 | STKc_PASK |
| cd14157 | 354-540 | STKc_IRAK2 |
| cd14086 | 335-536 | STKc_CaMKII |
| cd07842 | 332-540 | STKc_CDK8_like |
| cd05086 | 337-546 | PTKc_Aatyk2 |
| cd14039 | 337-540 | STKc_IKK_alpha |
| cd05607 | 336-540 | STKc_GRK7 |
| cd07873 | 337-539 | STKc_PCTAIRE1 |
| cd05103 | 334-597 | PTKc_VEGFR2 |
| cd14160 | 371-604 | PK_IRAK3 |
| cd14220 | 337-608 | STKc_BMPR1a |
| cd05605 | 336-540 | STKc_GRK4_like |
| cd14037 | 335-536 | STKc_NAK_like |
| cd05586 | 337-539 | STKc_Sck1_like |
| cd14175 | 335-536 | STKc_RSK1_C |
| cd05617 | 330-541 | STKc_aPKC_zeta |
| cd14165 | 376-536 | STKc_TSSK1_2-like |
| cd14067 | 373-540 | STKc_LRRK1 |
| cd07855 | 335-541 | STKc_ERK5 |
| cd05610 | 337-540 | STKc_MASTL |
| cd13995 | 330-536 | STKc_MAP3K8 |
| cd05630 | 336-542 | STKc_GRK6 |
| cd07844 | 335-474 | STKc_PCTAIRE_like |
| cd05591 | 335-542 | STKc_nPKC_epsilon |
| cd14171 | 337-536 | STKc_MAPKAPK5 |
| cd05631 | 333-542 | STKc_GRK4 |
| cd13977 | 406-536 | STKc_PDIK1L |
| cd05598 | 337-543 | STKc_LATS |
| cd14109 | 332-535 | PK_Unc-89_rpt1 |
| cd05588 | 336-540 | STKc_aPKC |
| cd14197 | 330-535 | STKc_DRAK1 |
| cd05104 | 431-602 | PTKc_Kit |
| cd13975 | 425-592 | PKc_Dusty |
| cd07877 | 337-540 | STKc_p38alpha |
| cd14132 | 337-540 | STKc_CK2_alpha |
| cd07856 | 337-540 | STKc_Sty1_Hog1 |
| cd05599 | 335-541 | STKc_NDR_like |
| cd14198 | 337-535 | STKc_DRAK2 |
| cd14219 | 337-604 | STKc_BMPR1b |
| cd14114 | 335-535 | STKc_Twitchin_like |
| cd07849 | 335-540 | STKc_ERK1_2_like |
| cd14115 | 337-535 | STKc_Kalirin_C |
| cd14113 | 330-535 | STKc_Trio_C |
| cd07870 | 332-540 | STKc_PFTAIRE2 |
| cd14174 | 335-536 | STKc_Mnk1 |
| cd05601 | 336-540 | STKc_CRIK |
| cd14181 | 335-536 | STKc_PhKG2 |
| cd08227 | 336-539 | PK_STRAD_alpha |
| cd13991 | 337-597 | STKc_NIK |
| cd07853 | 337-541 | STKc_NLK |
| cd05596 | 336-540 | STKc_ROCK |
| cd07850 | 438-543 | STKc_JNK |
| cd05632 | 336-542 | STKc_GRK5 |
| cd14035 | 354-539 | PK_MADML |
| cd08368 | Dec-64 | LIM |
| cd14223 | 336-540 | STKc_GRK2 |
| cd07858 | 337-541 | STKc_TEY_MAPK |
| cd07876 | 376-540 | STKc_JNK2 |
| cd05633 | 336-540 | STKc_GRK3 |
| cd14110 | 339-534 | STKc_obscurin_rpt2 |
| cd14178 | 335-536 | STKc_RSK3_C |
| cd07857 | 337-541 | STKc_MPK1 |
| cd14176 | 335-536 | STKc_RSK2_C |
| cd07880 | 337-540 | STKc_p38gamma |
| cd14182 | 335-536 | STKc_PhKG1 |
| cd07874 | 376-540 | STKc_JNK3 |
| cd07878 | 337-540 | STKc_p38beta |
| cd05037 | 331-594 | PTK_Jak_rpt1 |
| cd14177 | 335-536 | STKc_RSK4_C |
| cd07854 | 327-540 | STKc_MAPK4_6 |
| cd13984 | 383-597 | PK_NRBP1_like |
| cd14173 | 332-536 | STKc_Mnk2 |
| cd14068 | 336-540 | STKc_LRRK2 |
| cd14108 | 332-537 | STKc_SPEG_rpt1 |
| cd05625 | 335-542 | STKc_LATS1 |
| cd14107 | 335-535 | STKc_obscurin_rpt1 |
| cd14094 | 335-536 | STKc_CASK |
| cd08368 | 72-125 | LIM |
| pfam00412 | 72-125 | LIM |
| smart00132 | 72-124 | LIM |
| TIGR03724 | 403-474 | arch_bud32 |
| COG3642 | 403-474 | Bud32 |
| smart00221 | 334-601 | STYKc |
| smart00219 | 334-601 | TyrKc |
| smart00220 | 334-592 | S_TKc |
| pfam07714 | 334-597 | Pkinase_Tyr |
| pfam00069 | 334-592 | Pkinase |
| COG0515 | 332-540 | SPS1 |
| PTZ00263 | 330-540 | PTZ00263 |
| PLN00034 | 294-538 | PLN00034 |
| PTZ00024 | 322-542 | PTZ00024 |
| PLN00009 | 335-542 | PLN00009 |
| PRK13184 | 337-540 | pknD |
| PTZ00426 | 337-540 | PTZ00426 |
| PHA03209 | 348-551 | PHA03209 |
| PLN00113 | 336-605 | PLN00113 |
| PTZ00267 | 336-540 | PTZ00267 |
| PHA03210 | 376-542 | PHA03210 |
| TIGR03903 | 358-543 | TOMM_kin_cyc |
| PTZ00266 | 337-539 | PTZ00266 |
| PTZ00036 | 334-540 | PTZ00036 |
| PHA03212 | 375-622 | PHA03212 |
| PTZ00283 | 441-597 | PTZ00283 |
| TIGR00225 | 147-224 | prc |
| TIGR02037 | 191-238 | degP_htrA_DO |
Ontology Information
| HPRD ID | 1748 |
|---|---|
| Molecular Class | Serine/threonine kinase |
| Molecular Function | Chaperone activity (GO:0003754) |
| Biological Process | Protein metabolism (GO:0019538) |
Drug Information
No matching records could be found.