CoReCG

Evidence Information

Pubmed ID	Year	Sample Information	Techniques	Mechanism	Fold Change	Remark
22930170	2012	Cell line : KM 12C, KM 12SM , HT 30 Source : ATCC Sample Type : - No. of Sample : - Stage : -	Microarray analysis,Real time RT-PCR and Flow cytometry	Down-regulation	-	Gene differentially expressed and analysed bye by Microarray.
20089989	2010	Cell line : - Source : VU University Medical Center, Amsterdam, The Netherlands. Sample Type : CRC tumor and normal tissue No. of Sample : - Stage : -	Biochemical isolation to nano-LC-MS/MS analysis	Up-regulation	-	This genes are differenitially expressed between colorectal adenoma and Colorectal cancer tissue. CRC tissue was collected at the VU University Medical Center, Amsterdam, The Netherlands.

Gene Details

Chromosome: 12; NC_000012.11 (91497232..91505542, complement)
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Gene Type	protein coding
Gene Family	Proteoglycans / Extracellular Matrix : Small leucine-rich repeats
Description	This gene encodes a member of the small leucine-rich proteoglycan (SLRP) family that includes decorin, biglycan, fibromodulin, keratocan, epiphycan, and osteoglycin. In these bifunctional molecules, the protein moiety binds collagen fibrils and the highly charged hydrophilic glycosaminoglycans regulate interfibrillar spacings. Lumican is the major keratan sulfate proteoglycan of the cornea but is also distributed in interstitial collagenous matrices throughout the body. Lumican may regulate collagen fibril organization and circumferential growth, corneal transparency, and epithelial cell migration and tissue repair. [provided by RefSeq, Jul 2008]
Chromosome	12
Location	12q21.3-q2
Start	91103455
End	91111765
Strand	-
Gene Sequence	>gi\|568815586:c91111765-91103455 Homo sapiens chromosome 12, GRCh38.p2 Primary Assembly ACAGTGAGCTTCCTTATTTGAAGCAGGACTCAATTCTTGGTTAAAAGCTATGGTATTTGAGCTAGTTAAA CACATATCTCTCTCCCATTCCATAGGGAATGAGCTGGGCTGTCCTTTCTCCCCACGTTCACCTGCACTTC GTTAGAGAGCAGTGTTCACATGCCACACCACAAGATCCCCACAATGACATAACTCCATTCAGAGACTGGC GTGACTGGGCTGGGTCTCCCCACCCCCCTTCAGCTCTTGTATCACTCAGAATCTGGCAGCCAGTTCCGTC CTGACAGAGTTCACAGCATATATTGGTGGATTCTTGTCCATAGTGCATCTGCTTTAAGAATTAACGAAAG CAGTGTCAAGACAGTAAGGTAAGTGCTGTTTTAACTATTGCACTGGGGATGTTAACTGTTTGGGACAGCG TTTTTTGTAACAGGAACAGGAAAAATTCCAGAGCAATTTTGCCAATTGCTATTCAACAGCAAATCCACAG TTCTGAGCATTTAGTTTCACATTTTGTTAATATGTTTTCCATGATTTATAGATTTGAGATTTTATACAGT ATATGCTGTATTGCTTGGCAAGAGAAGTTATAAAAAGTTTCAAGGTTAGAATGAGAAAATAGTTAAAGTA GACACAGTGAAAAAATATAGAAATTAATATGTTTGTTATGTATGCTAGTTAGTTATATATGTTAGTATTG GACCCTAATACTGGAGCAAAGAAAAGTCATTTTAATCAGCATTCAAAATATCTTTTAATAAGCATATTGT GACAATTTGTTATAATTTACAATAAACGTTCTATGTTATAAAACATGAGCTAAAAGATTTAGGAACTCTT ATGGATTATTTATTTCTGTTTTGTTAATTTAAAAAATTTGTTTCTTGGATATATGCCTTAAGGAACGAGT TTTTTAAAAAGTTCTGGGAAATGATTTCGTTTTTGAAAACAGCATTTTCTCTATAGCCACAGGTATTTGA AAAAACTGAGGGTAGTACAGTGTGATTTTGCCTCATAGTGGAGTCATTATATGGTTGCAAACTCTCATTC AATTCAGCATCCTTGTTTTTACTTTGCCAAAAAATATGGAAGCATTTTTCATTACTATTTAATACTCACA TTATAGTTGCCATATTTTGGTGTATAGTAAATTTAAAATAGCTTATTAATAAAGCAAGACAAATCTTTAC AGTATTTACATTCTATAACTTAAAATAACTCTGGGAATATGTCATCACGTTCTTTTTAGTGCTATGCAAT TATTATTATGGCCAAGTTCTGTCAGCAAAATTAAATGCCCCCATTAAAATCTTAGAGAGTAATTTACTGA GAATCTGGCTACATGTTACCTTATGTCAGCAATCAAAGTATTTCTAAAAGCTGTTTTATAACGTTCCATC TGATCTGAAATAAAGTGCCTTACAATTTCAAATTAAAACAAATAAAAGACGTTTTCAGTTTCTAACCCCA AAGATCCTGCTTATCCCAAACTACTTTGATCCAAAAGCTTGTAATCATACTTTCATAGAAAGATATAATA TTCTCAGTTATCTATTAGAATGTAGATCTTTCGTCACATTAATGATTTATCTCCCAGGGCTACCAACTTT GCCTCAGCCACAACTGTTCACTCTATAAAAGTCTAACTCTTATATTCCAATTTTCCCATATCTAAATTGC TGCACCTAAGACATTGAAATGTACTTTTTTGAGCCTCACCTTAGAAACATGTTCCTATGAGAAGATAACT GTTACACATTATTTCAAATTCATATTCTCAATTGAATAATTTACTAGATAGTTCTAACACCAGTATTAAA TCCAAACTTTAAAAACATCACACCTCTCTCCCACCTCCATTCTGTGAGGCCACTAAAAGCCAGATATGCA AACCATGGCATCTTCGATTTTGGCATGAAGAAAGTAGAGAACTTGTGAGTAATTGAGAGAGACTATAACT CTAATTGAAAACTTGGAAAATACTATCTTTCTCTACCTGTTGAATCTCTTTCCAGAAAGAGAAACCTTCA GAATGTGTGACATTTTCCTGATAAACATTAGCAATTATTAAATATTACTAATATTTTGTTTAGTAAATAG CTAATTTATGAAATATTAGTTCCAGAACACAGTTTTGCAATGTGCTTTAAAAAGTGTAGAATGTTAAGCA CAACATGAACTAGTATGCATGCACACCAGCACCAAGAATTCTGTTCTCCTTCCTCAGAACCAACAGTAAC CAGACACTTTTAAAGGAATGTGCCTTCCATTTCCCTCCCACATACAAGCAAAACCTCAGGTTGCCCATAT TCCCGTAAGGATCTTCTTCATGAGTCATTTTAATGATGTCGAATGGTAGGGTAGAGTATACAGTTAAAAA CTGTCTTCTCATTCTCTTTTTTTGAGAGATGATCTGAAGCAGTAGTCTAATTCGGTGGTCAATGAACACC ACCCAGAAACCTCTTACAGGAAGGCATTTCATTAAGGAAGAGCCTGGAGATTGACTGGAACAATTAGGCT GGGCTCGCCCAGAAGGGGGCGCACGTGTACGCAATCTAACCTGAAAGCTGCTCACTACATAGTTGTAAAC ATACACCTTTGTCCTCATACCTAAATAAAAATTTAAAAGACGCTGTTAGATGCACTAAAAATAGCTATAA AATAACAAAATGCACATTTTCTAATGAATTTAATGTTGCAAATTGAATGTCTTTTTCTTGAAAGTATATA TTTTTTTAATTAATAAATGTTTCATCTTTATTTAGGATTCAAACCATTTGCCAAAAATGAGTCTAAGTGC ATTTACTCTCTTCCTGGCATTGATTGGTGGTACCAGTGGCCAGTACTATGATTATGATTTTCCCCTATCA ATTTATGGGCAATCATCACCAAACTGTGCACCAGAATGTAACTGCCCTGAAAGCTACCCAAGTGCCATGT ACTGTGATGAGCTGAAATTGAAAAGTGTACCAATGGTGCCTCCTGGAATCAAGTATCTTTACCTTAGGAA TAACCAGATTGACCATATTGATGAAAAGGCCTTTGAGAATGTAACTGATCTGCAGTGGCTCATTCTAGAT CACAACCTTCTAGAAAACTCCAAGATAAAAGGGAGAGTTTTCTCTAAATTGAAACAACTGAAGAAGCTGC ATATAAACCACAACAACCTGACAGAGTCTGTGGGCCCACTTCCCAAATCTCTGGAGGATCTGCAGCTTAC TCATAACAAGATCACAAAGCTGGGCTCTTTTGAAGGATTGGTAAACCTGACCTTCATCCATCTCCAGCAC AATCGGCTGAAAGAGGATGCTGTTTCAGCTGCTTTTAAAGGTCTTAAATCACTCGAATACCTTGACTTGA GCTTCAATCAGATAGCCAGACTGCCTTCTGGTCTCCCTGTCTCTCTTCTAACTCTCTACTTAGACAACAA TAAGATCAGCAACATCCCTGATGAGTATTTCAAGCGTTTTAATGCATTGCAGTATCTGCGTTTATCTCAC AACGAACTGGCTGATAGTGGAATACCTGGAAATTCTTTCAATGTGTCATCCCTGGTTGAGCTGGATCTGT CCTATAACAAGCTTAAAAACATACCAACTGTCAATGAAAACCTTGAAAACTATTACCTGGAGGTCAATCA ACTTGAGAGTAAGTAAAAAGCTGTTCCTGTGTTTGATGTGTGCTCAAGTGTTTAAATACCTGGGCTGCAC AACACAGATATTGCATCTGGCTCCATTAAAAAAACAAAATGTCGCCCGGGCGCTGTGGCTCATTCCTGTA AATCCAGCATTTTGGGAGGCCGAAGTGGGCGGATCACCAGGTCAGGAGTTGAGACCAGCCTGGCCAACAT GATGAAACCCCATCTCTACTAAAAATACAAAAATTAGCCAGGCGTGGTGTCGCACTTCTGTAATCCCAGC TACTCAGGAGGCTGAGCCAGGAGAATTGCTTGAACCTGGGAGATAGAGGTTGCAGTGAGCCGAGATCGTG CCACTGTACTCAAGCCTGGGCAAGACAGCCAGATTCTGTCTTGGAAAAAAAAAAAATGTCCACAAAATAT CCCTCTACTTCAAACAAAGAATAATTCTAGCTCAATCATATATCCAATATCCAGCCTTTCTTTGGTGTAT CCAGATAAGGAACAATTAAGGTCACAGAATTTAATATGTAAGTCTTCAAACTAAAAATTCCGGGCCAACT CATCCTGCTGTGTTACCTCCTCATATATATCTCTTATTATTTTCTCCTTTATGGCTTAGATTTGTGTCCT ACATTTATTTTTTGACAAGATCTAGATGAGGGAGGAAGAAATGAGTTCAAAAGTGGCACAGTTGGCAAAC TCCATAGCCACAAAGAAGCCCATATTGTCCCTCCCTCCCTCCCTCTCTCTCTCTTTTTCTTTCTTCCTTC CTTTCTTTCCCTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTTCTCT TTCTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTTCCTTTCTTTCTTTCTTCTTTCTCT CTTTCTTTCTTTCTTTTTCTTTCCTTCTTTCTTTCTTTCGTTTTCTTTCTTTCTTTCTTTCTTTTTTTTT TTGACAGGGTCTCACTCTGTCGCCCAGACTGGAGTGAGGTGGTGCAATCTCGGCTCATTGCAACCTCCAC CCCCCAGGCTCAGGCGATTCTCCCACCTCAGGCCACCACCACCACCAGGCTAATTTTTATGTTTTTAGTA GAGATGGGGTTTCACCATGTTAACCAGGCTGTTCTTAAAATCCTGACCTCAACTGATCCATCTGCCTTGG CCTCCCAAAGTACTGGGATTACAGGCGTGAGCCACTGTGCCTGGCCCCATATAGTCTCATGGTCTTCCCT GACATCAACTACTTGGGACTCACCATGTTACTCTGCTGTCATGATCATCATCTGCCTCTGTTATCTCTGT TATGGTGTGTGGCCATCACAGTGCTCTGGAGGACTGTGAAGAAGATTAAAGAGAAAAAGAAATATGATGG GAGATTCTAACATCTTTTTTTTTTTTTTTTTTTTTAGAAGAAAAATAGTGTTACAGAGCTTTTTTTTTCT TGGGTACAATCCTGCCCCTCATTTGATATTTCCACACTTTCTCTTTCTCCTCTCTTTATTTTTCATTTAT CTTCTGGATGAAGTTTGATCTGATGCATTTGGACTGCTTATGCACTTATGTGGTCTTCAGGGACATTCTT CAACTTAAGCAGTATAGATTCCAATGGGAAATTGAAATCCACCATTTCCTACCAGGATAACTCTGCCATT AATCTTTGGCAGAGCTTGGTAGAAGAGAAAAACCATGATTCACAGATAAGGCTTTCTAAATGAAAAAATC AAGCAGGAAACATTGATTCACATATAAAGTAATAATGTCTGCAAAATAATCTATTGAATTTGAACATCTC TACATGATGAAAATTGGTTTTCTGGCCATGCTGAATAAAGGTATTGCTGTCAGAAAATATTACAATATAT TTTATGCATATGATGTTTGTTAATTCTGCCAGTTTCATATAACCTCTAGTAGGGTTAAACGTTTTCATAA AGAAGACCATACTCGCCAACTCTGAAGCTCCACATGTTCTTTGTTGTTTCTGAAAAGCAGCCAAGGTAAG GGTTGGTGCTGTTTGACTGTCACACAATACACAGTCAGGCTAACACAGCTAAACCCCTCTTGTTGTTTCC AGTGGAAAATTCACTATGTGGCCATATGTGATTCCTCATTTTAAACATATGTGGTTAGGAGGAAGGATAC TCTCTGACAGACCAAAATGCTAAAGGAATTTACGATGCTTAAGGGATGACGGAGTACATTAGATTTGGTG GGTAGAGATTATTCGTAAGAGCAGGGCTACTTCTTTCTCTGAAACAAAGAAGGATACAGAAGTAGGCACA TTTGAAGGTATACATTGCATGAGTAAAGGATGGAAGAGAGGTCTATGGGAGAAAGGCCAACGGCCTGTCA GTGCCAAGCTGAGATAGAAACCACAGTGCCCAGTACATAGTGGTCATTTGAAAAGGTAACATAATAGTTT CCTTTCTTTCTTCCTTATCTTTGTACATTTAGTCAGGTATTCTCCTTGTCTTTTTATGTATCACCTCAGT TTAGGTTATTTTGCCAGATAATAATCAACTATATCAACATTTCACATTCACTTAATACAGAAAGTTCCCC TCAATGTTTTTTTCTAATATTAGGGAATATATAGCCAAAACAAACTGTTTTCTATTTCAAACTTGCAACT CTAAGCATTAGCCCAATCAGAGATCTTCCTAGTGTAGAGTAATTTAGAAAGACAGCAAAATCAAAAGGAT ATTAGTCATTATTTAGGACATACTATGTACTAGTATTGTGTGAAGTGCTCTACACAACTTAATTTAATCT TCATGCAACACGGTAAGATAGATGTGTTATTTCTAACAAGATCAGATAAGTGTTCCAGTGTTGCCCACCT GGGTAAGTGGCAGAGGTAGAATTCCAAGATGGGACTATGCCCATCTTCTTTCCATTTTTCCTCACTTTCT CAAATGTTGGTACCATAGAAAAATCCCTGGAATTAACTGATGAGTTATTTTAAAAAGCATGTGTGTTTGG GGTTCCACTGAAGTCTTTGTTAACTAGAGTTTGAAAATGAAAACAAGATAAAGGACTTGAAAATGTTAAT CTAAAATAGACATAGGCAAACATAGTTTCTGTGTATACACAGGTCAGTCAATTCAGTAACACTCTTGGTT TCTATTACAAAGTAAGTCAGTGTTTCATTTGTGGCAGCTTTTTGACCATGGACAAAAATAAACAAATAAA CAAAAACATGAGTTCAGATGGTGGACATGCCATGATTAGGTTTTTGCCTTAGAATTTTGATCATTGCTAT GGTGTGTGATTGCTGGAATGATTTGGTTTTTGTCTTGGAATTTTTATCATGGTCATGGTATGTGGTTGCT AGAAAATTCTTTATAGATCATCTAGTTAACCCTTCTTATTTTTAGATGTAAAACCAAAGAGTACTTATAC TGAGATTGTTCATACAACAATGGGATCCATTTATATTTCTTCAGGTTATACTATTTCAAAAAAGTTGTTA GATAATATGACACACTTATTGAATGCCTTTTTAAAAACAACTTCTAGTAATAAAATAAGTTCTGTTATTT AAAATATTCCACTGAATATCTTGATCTACCATGATTACTCTTTACTAAATGTTACTGTGCCATTTTGGTA GCCTGAAATATGCCTTTAATGGTTGCAAATTCAAACATATACTATATTATGACTTTTCTAAATGGGAAGA GGTCCTATTTTATAATATATTAAACATAAATTTTTTGTATTGTTTTGAGCCAGTGTACTGAAAAATGATT AATGTTTTCTATTCTTTAATTTTTAGAGTTTGACATAAAGAGCTTCTGCAAGATCCTGGGGCCATTATCC TACTCCAAGATCAAGCATTTGCGTTTGGATGGCAATCGCATCTCAGAAACCAGTCTTCCACCGGATATGT ATGAATGTCTACGTGTTGCTAACGAAGTCACTCTTAATTAATATCTGTATCCTGGAACAATATTTTATGG TTATGTTTTTCTGTGTGTCAGTTTTCATAGTATCCATATTTTATTACTGTTTATTACTTCCATGAATTTT AAAATCTGAGGGAAATGTTTTGTAAACATTTATTTTTTTTAAAGAAAAGATGAAAGGCAGGCCTATTTCA TCACAAGAACACACACATATACACGAATAGACATCAAACTCAATGCTTTATTTGTAAATTTAGTGTTTTT TTATTTCTACTGTCAAATGATGTGCAAAACCTTTTACTGGTTGCATGGAAATCAGCCAAGTTTTATAATC CTTAAATCTTAATGTTCCTCAAAGCTTGGATTAAATACATATGGATGTTACTCTCTTGCACCAAATTATC TTGATACATTCAAATTTGTCTGGTTAAAAAATAGGTGGTAGATATTGAGGCCAAGAATATTGCAAAATAC ATGAAGCTTCATGCACTTAAAGAAGTATTTTTAGAATAAGAATTTGCATACTTACCTAGTGAAACTTTTC TAGAATTATTTTTCACTCTAAGTCATGTATGTTTCTCTTTGATTATTTGCATGTTATGTTTAATAAGCTA CTAGCAAAATAAAACATAGCAAATGGCATCACTGTGTTTGACTTCTTGTGAAATTTCTGTACTTTGTATA TAAAATACATAAAACAATAGATTAGAAATCAAAAGATATCTCTGGCCTGCA Download Select all
Length	8311
OMIM ID	600616
HGNC ID	HGNC:6724
Unigene ID	Hs.406475
Ensembl ID	ENSG00000139329
PharmGKB ID	-

mRNA Information

mRNA ID	NM_002345.3
Exon	join(1..368,2766..3648,7447..8311)
mRNA Sequence	>4060 ACAGTGAGCTTCCTTATTTGAAGCAGGACTCAATTCTTGGTTAAAAGCTATGGTATTTGAGCTA GTTAAACACATATCTCTCTCCCATTCCATAGGGAATGAGCTGGGCTGTCCTTTCTCCCCACGTT CACCTGCACTTCGTTAGAGAGCAGTGTTCACATGCCACACCACAAGATCCCCACAATGACATAA CTCCATTCAGAGACTGGCGTGACTGGGCTGGGTCTCCCCACCCCCCTTCAGCTCTTGTATCACT CAGAATCTGGCAGCCAGTTCCGTCCTGACAGAGTTCACAGCATATATTGGTGGATTCTTGTCCA TAGTGCATCTGCTTTAAGAATTAACGAAAGCAGTGTCAAGACAGTAAGGATTCAAACCATTTGC CAAAAATGAGTCTAAGTGCATTTACTCTCTTCCTGGCATTGATTGGTGGTACCAGTGGCCAGTA CTATGATTATGATTTTCCCCTATCAATTTATGGGCAATCATCACCAAACTGTGCACCAGAATGT AACTGCCCTGAAAGCTACCCAAGTGCCATGTACTGTGATGAGCTGAAATTGAAAAGTGTACCAA TGGTGCCTCCTGGAATCAAGTATCTTTACCTTAGGAATAACCAGATTGACCATATTGATGAAAA GGCCTTTGAGAATGTAACTGATCTGCAGTGGCTCATTCTAGATCACAACCTTCTAGAAAACTCC AAGATAAAAGGGAGAGTTTTCTCTAAATTGAAACAACTGAAGAAGCTGCATATAAACCACAACA ACCTGACAGAGTCTGTGGGCCCACTTCCCAAATCTCTGGAGGATCTGCAGCTTACTCATAACAA GATCACAAAGCTGGGCTCTTTTGAAGGATTGGTAAACCTGACCTTCATCCATCTCCAGCACAAT CGGCTGAAAGAGGATGCTGTTTCAGCTGCTTTTAAAGGTCTTAAATCACTCGAATACCTTGACT TGAGCTTCAATCAGATAGCCAGACTGCCTTCTGGTCTCCCTGTCTCTCTTCTAACTCTCTACTT AGACAACAATAAGATCAGCAACATCCCTGATGAGTATTTCAAGCGTTTTAATGCATTGCAGTAT CTGCGTTTATCTCACAACGAACTGGCTGATAGTGGAATACCTGGAAATTCTTTCAATGTGTCAT CCCTGGTTGAGCTGGATCTGTCCTATAACAAGCTTAAAAACATACCAACTGTCAATGAAAACCT TGAAAACTATTACCTGGAGGTCAATCAACTTGAGAAGTTTGACATAAAGAGCTTCTGCAAGATC CTGGGGCCATTATCCTACTCCAAGATCAAGCATTTGCGTTTGGATGGCAATCGCATCTCAGAAA CCAGTCTTCCACCGGATATGTATGAATGTCTACGTGTTGCTAACGAAGTCACTCTTAATTAATA TCTGTATCCTGGAACAATATTTTATGGTTATGTTTTTCTGTGTGTCAGTTTTCATAGTATCCAT ATTTTATTACTGTTTATTACTTCCATGAATTTTAAAATCTGAGGGAAATGTTTTGTAAACATTT ATTTTTTTTAAAGAAAAGATGAAAGGCAGGCCTATTTCATCACAAGAACACACACATATACACG AATAGACATCAAACTCAATGCTTTATTTGTAAATTTAGTGTTTTTTTATTTCTACTGTCAAATG ATGTGCAAAACCTTTTACTGGTTGCATGGAAATCAGCCAAGTTTTATAATCCTTAAATCTTAAT GTTCCTCAAAGCTTGGATTAAATACATATGGATGTTACTCTCTTGCACCAAATTATCTTGATAC ATTCAAATTTGTCTGGTTAAAAAATAGGTGGTAGATATTGAGGCCAAGAATATTGCAAAATACA TGAAGCTTCATGCACTTAAAGAAGTATTTTTAGAATAAGAATTTGCATACTTACCTAGTGAAAC TTTTCTAGAATTATTTTTCACTCTAAGTCATGTATGTTTCTCTTTGATTATTTGCATGTTATGT TTAATAAGCTACTAGCAAAATAAAACATAGCAAATGGCATCACTGTGTTTGACTTCTTGTGAAA TTTCTGTACTTTGTATATAAAATACATAAAACAATAGATTAGAAATCAAAAGATATCTCTGGCC TGCA Download Select all
Length	2116

CDS Information

Location	join(2787..3648,7447..7601)
CDS Sequence	>gi\|61742794:390-1406 Homo sapiens lumican (LUM), mRNA ATGAGTCTAAGTGCATTTACTCTCTTCCTGGCATTGATTGGTGGTACCAGTGGCCAGTACTATGATTATG ATTTTCCCCTATCAATTTATGGGCAATCATCACCAAACTGTGCACCAGAATGTAACTGCCCTGAAAGCTA CCCAAGTGCCATGTACTGTGATGAGCTGAAATTGAAAAGTGTACCAATGGTGCCTCCTGGAATCAAGTAT CTTTACCTTAGGAATAACCAGATTGACCATATTGATGAAAAGGCCTTTGAGAATGTAACTGATCTGCAGT GGCTCATTCTAGATCACAACCTTCTAGAAAACTCCAAGATAAAAGGGAGAGTTTTCTCTAAATTGAAACA ACTGAAGAAGCTGCATATAAACCACAACAACCTGACAGAGTCTGTGGGCCCACTTCCCAAATCTCTGGAG GATCTGCAGCTTACTCATAACAAGATCACAAAGCTGGGCTCTTTTGAAGGATTGGTAAACCTGACCTTCA TCCATCTCCAGCACAATCGGCTGAAAGAGGATGCTGTTTCAGCTGCTTTTAAAGGTCTTAAATCACTCGA ATACCTTGACTTGAGCTTCAATCAGATAGCCAGACTGCCTTCTGGTCTCCCTGTCTCTCTTCTAACTCTC TACTTAGACAACAATAAGATCAGCAACATCCCTGATGAGTATTTCAAGCGTTTTAATGCATTGCAGTATC TGCGTTTATCTCACAACGAACTGGCTGATAGTGGAATACCTGGAAATTCTTTCAATGTGTCATCCCTGGT TGAGCTGGATCTGTCCTATAACAAGCTTAAAAACATACCAACTGTCAATGAAAACCTTGAAAACTATTAC CTGGAGGTCAATCAACTTGAGAAGTTTGACATAAAGAGCTTCTGCAAGATCCTGGGGCCATTATCCTACT CCAAGATCAAGCATTTGCGTTTGGATGGCAATCGCATCTCAGAAACCAGTCTTCCACCGGATATGTATGA ATGTCTACGTGTTGCTAACGAAGTCACTCTTAATTAA Download Select all
CCDS ID	CCDS9038.1

Protein Information

Protein ID	NP_002336.1
Protein Name	Lumican
Molecular Wt. (Da)	36661
Protein Sequence	>4060 MSLSAFTLFLALIGGTSGQYYDYDFPLSIYGQSSPNCAPECNCPESYPSAMYCDELKLKSVPMV PPGIKYLYLRNNQIDHIDEKAFENVTDLQWLILDHNLLENSKIKGRVFSKLKQLKKLHINHNNL TESVGPLPKSLEDLQLTHNKITKLGSFEGLVNLTFIHLQHNRLKEDAVSAAFKGLKSLEYLDLS FNQIARLPSGLPVSLLTLYLDNNKISNIPDEYFKRFNALQYLRLSHNELADSGIPGNSFNVSSL VELDLSYNKLKNIPTVNENLENYYLEVNQLEKFDIKSFCKILGPLSYSKIKHLRLDGNRISETS LPPDMYECLRVANEVTLN Download Select all
Length	338
Uniprot ID	P55287
Ensembl Protein ID	ENSP00000268603

Post-translational Modification Information (Source : HPRD)

Residue	Type	site
N	Glycosylation	160
N	Glycosylation	88
Y	Sulfation	20
Y	Sulfation	21
Y	Sulfation	23
N	Glycosylation	127

Enzyme Information

No matching records could be found.

PPi Information

(Click to view network : Source STRING) View

Interactant Gene ID (Source: HPRD)	Gene Symbol	HPRD ID	Ref Seq ID	Technique	References
176	ACAN	1123	NP_037359.3	in vitro	15505028
1278	COL1A2	363	NP_000080.2	in vitro	10734230
6434	TRA2B	4097	NP_004584.1	yeast 2-hybrid	16169070

Pathway Information

Pathway Name	Pathway ID
Proteoglycans in cancer	hsa05205

Structure Information

No matching records could be found.

Domain Information

ID	Location	Description
smart00013	37-71	LRRNT
cl02423	37-71	LRRNT superfamily
cd00116	66-267	LRR_RI
cl23707	66-267	LRR_RI superfamily
pfam01462	37-66	LRRNT
cd00116	155-319	LRR_RI
pfam12799	137-173	LRR_4
cl19302	137-173	LRR_4 superfamily
pfam12799	184-221	LRR_4
pfam13855	206-266	LRR_8
pfam13855	138-196	LRR_8
pfam13855	66-128	LRR_8
PRK15370	42-242	PRK15370
COG4886	88-278	LRR
PLN00113	110-266	PLN00113
PRK15387	31-321	PRK15387
COG4886	65-279	LRR
PLN00113	92-317	PLN00113
PRK15370	44-204	PRK15370
PLN00113	88-266	PLN00113
COG4886	156-322	LRR
pfam13855	160-217	LRR_8
COG4886	65-240	LRR
pfam13855	92-171	LRR_8
PLN00113	154-266	PLN00113
PLN03150	210-270	PLN03150
PLN00113	195-266	PLN00113

Ontology Information

HPRD ID	4312
Molecular Class	Extracellular matrix protein
Molecular Function	Cell adhesion molecule activity (GO:0005194)
Biological Process	Transport (GO:0006810)

SNP Information

View SNP Geneview Report