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General Information



Gene_Symbol Gene_ID Gene_Name Chromosome Alias
TACSTD2 4070 tumor-associated calcium signal transducer 2  1TROP2, GA733-1, EGP-1 







  • Evidence
  • Gene
  • mRNA
  • CDS
  • Protein
  • PTM
  • Enzyme
  • PPi
  • Pathway
  • Structural
  • Domain
  • Ontology
  • SNP
  • Drug
  • External Links



Evidence Information


Pubmed ID Year Sample Information Techniques Mechanism Fold Change Remark
21423092   2011Cell line : -

Source : -

Sample Type : CRC tumor and normal tissues

No. of Sample : 37

Stage : TNM Stage I-IV

real time RT-PCRMutation-SERIN1, TACSTD2 and KRAS codon 12 mutation are not associated with clinical-pathological characteristics of colorectal cancer.


Gene Details



NC_000001.10 (59041095..59043166, complement)

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Gene Type protein coding
Gene Family -
Description This intronless gene encodes a carcinoma-associated antigen. This antigen is a cell surface receptor that transduces calcium signals. Mutations of this gene have been associated with gelatinous drop-like corneal dystrophy.[provided by RefSeq, Dec 2009]  
Chromosome 1
Location 1p32
Start 59041095  
End 59043166  
Strand -  
Gene Sequence

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Length 2072  
OMIM ID 137290   
HGNC ID HGNC:11530   
Unigene ID Hs.23582   
Ensembl ID ENSG00000184292   
PharmGKB ID PA36305   

mRNA Information


mRNA ID NM_002353.2
Exon 1..2072  
mRNA Sequence

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Length 2080  



CDS Information


   
Location339..1310
CDS Sequence

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CCDS ID CCDS609.1



Protein Information


      
Protein IDNP_002344.2
Protein Nametumor-associated calcium signal transducer 2
Molecular Wt. (Da)21501
Protein Sequence

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Length 323  
Uniprot IDP05549
Ensembl Protein ID ENSP00000316516  



Post-translational Modification Information (Source : HPRD)


Residue Type site
SPhosphorylation322;-

Enzyme Information


No matching records could be found.

PPi Information


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No matching records from HPRD source could be found.

Pathway Information


No matching records could be found.

Structure Information


No matching records could be found.

Domain Information




ID Location Description
cd0019172-145  TY
cl0015072-145  TY superfamily
pfam0008673-145  Thyroglobulin_1
smart00211106-147  TY


Ontology Information


   
HPRD ID1682
Molecular ClassCell surface receptor
Molecular FunctionMolecular function unknown (GO:0005554)
Biological ProcessCell growth and/or maintenance (GO:0008151)  



SNP Information


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Drug Information


No matching records could be found.

External Links


                                 
ArrayExpressGO
ICGCGO
Cancer3DGO
COSMICGO
NCGGO
TSGeneGO
Tumor Gene Family of DatabasesGO
CCDBGO
G2SBCGO
Osteosarcoma DatabaseGO
RCDBGO