Search results:
General Information
| Gene_Symbol | Gene_ID | Gene_Name | Chromosome | Alias |
|---|---|---|---|---|
| MAGOH | 4116 | Mago-nashi homolog, proliferation-associated (Drosophila) | 1 | MAGOH1; MAGOHA |
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 20089989 | 2010 | Cell line : - Source : VU University Medical Center, Amsterdam, The Netherlands. Sample Type : CRC tumor and normal tissue No. of Sample : - Stage : - | Biochemical isolation to nano-LC-MS/MS analysis | Down-regulation | - | - |
| 18360708 | 2008 | Cell line : HCT 116 Source : - Sample Type : - No. of Sample : - Stage : - | Onto-Express software, KEGG pathway analysis, Microarray data by RT-PCR and real-time PCR. | Up-regulation | - | - |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | - |
| Description | Drosophila that have mutations in their mago nashi (grandchildless) gene produce progeny with defects in germplasm assembly and germline development. This gene encodes the mammalian mago nashi homolog. In mammals, mRNA expression is not limited to the germ plasm, but is expressed ubiquitously in adult tissues and can be induced by serum stimulation of quiescent fibroblasts. [provided by RefSeq, Jul 2008] |
| Chromosome | 1 |
| Location | 1p32.3 |
| Start | 53226892 |
| End | 53238610 |
| Strand | - |
| Gene Sequence | Download Select all |
| Length | 11719 |
| OMIM ID | 602603 |
| HGNC ID | HGNC:6815 |
| Unigene ID | Hs.421576 |
| Ensembl ID | ENSG00000162385 |
| PharmGKB ID | - |
mRNA Information
| mRNA ID | NM_002370.3 |
|---|---|
| Exon | join(1..250,2976..3034,4959..5069,9657..9739,11467..11719) | mRNA Sequence | Download Select all |
| Length | 772 |
CDS Information
| Location | join(163..250,2976..3034,4959..5069,9657..9739, 11467..11566) |
|---|---|
| CDS Sequence | Download Select all |
| CCDS ID | CCDS577.1 |
Protein Information
| Protein ID | NP_002361.1 |
|---|---|
| Protein Name | Mago-nashi homolog, proliferation-associated (Drosophila) |
| Molecular Wt. (Da) | 17033 |
| Protein Sequence | Download Select all |
| Length | 146 |
| Uniprot ID | Q00534 |
| Ensembl Protein ID | ENSP00000265734 |
Post-translational Modification Information (Source : HPRD)
No matching records could be found.
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
| Interactant Gene ID (Source: HPRD) | Gene Symbol | HPRD ID | Ref Seq ID | Technique | References |
|---|---|---|---|---|---|
| 10971 | YWHAQ | 886 | NP_006817.1 | in vivo | 15324660 |
Pathway Information
| Pathway Name | Pathway ID |
|---|---|
| mRNA surveillance pathway | hsa03015 |
| RNA transport | hsa03013 |
| Spliceosome | hsa03040 |
Structure Information
| PDB ID | 1P27 |
|---|---|
| Resolution | 2 |
| Method | X-RAY DIFFRACTION |
| Chains | A,C |
| Molecule | Mago nashi protein homolog |
| Model | View |
Domain Information
| ID | Location | Description |
|---|---|---|
| cd11295 | 4-146 | Mago_nashi |
| cl03715 | 4-146 | Mago_nashi superfamily |
| pfam02792 | 4-146 | Mago_nashi |
Ontology Information
| HPRD ID | 2913 |
|---|---|
| Molecular Class | Cell cycle control protein |
| Molecular Function | Kinase regulator activity (GO:0019207) |
| Biological Process | Cell communication (GO:0007154); Signal transduction (GO:0007165) |
Drug Information
No matching records could be found.