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General Information



Gene_Symbol Gene_ID Gene_Name Chromosome Alias
MFI2 4241 Antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5  3MTF1; CD228; MAP97 







  • Evidence
  • Gene
  • mRNA
  • CDS
  • Protein
  • PTM
  • Enzyme
  • PPi
  • Pathway
  • Structural
  • Domain
  • Ontology
  • SNP
  • Drug
  • External Links



Evidence Information


Pubmed ID Year Sample Information Techniques Mechanism Fold Change Remark
22968445   2012Cell line : -

Source : Department of Pathology of Wrocaw Medical University.

Sample Type : -

No. of Sample : -

Stage : -

Laser capture microdissection,FFPE-FASP,SAX fractionation,LC-MSMS,Label-free quantitation.Up-regulation6.7-


Gene Details



Chromosome: 3; NC_000003.11 (196728611..196756687, complement)

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Gene Type protein coding
Gene Family CD molecules
Description The protein encoded by this gene is a cell-surface glycoprotein found on melanoma cells. The protein shares sequence similarity and iron-binding properties with members of the transferrin superfamily. The importance of the iron binding function has not yet been identified. This gene resides in the same region of chromosome 3 as members of the transferrin superfamily. Alternative splicing results in two transcript variants. [provided by RefSeq, Jul 2008]  
Chromosome 3
Location 3q28-q29
Start 196987559  
End 197029816  
Strand -  
Gene Sequence

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Length 42258  
OMIM ID 155750   
HGNC ID HGNC:7037   
Unigene ID Hs.184727   
Ensembl ID ENSG00000163975   
PharmGKB ID -   

mRNA Information


mRNA ID XM_006713644.2
Exon join(2..163,1907..2061,3058..3157,5332..5514,6704..6860, 8346..8413,12527..12714,13448..13628,14301..14452, 19023..19119,20005..20199,20852..21008,21093..21160, 23081..23268,25637..25916,40670..42258)  
mRNA Sequence

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Length 3963  



CDS Information


   
Location join(115..163,1907..2061,3058..3157,5332..5514,6704..6860, 8346..8413,12527..12714,13448..13628,14301..14452, 19023..19119,20005..20199,20852..21008,21093..21160, 23081..23268,25637..25916,40670..40692)
CDS Sequence

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CCDS ID -



Protein Information


      
Protein IDNP_005920.2
Protein NameAntigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5
Molecular Wt. (Da)78209
Protein Sequence

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Length 738  
Uniprot IDP42771
Ensembl Protein ID ENSP00000307101  



Post-translational Modification Information (Source : HPRD)


No matching records could be found.

Enzyme Information


No matching records could be found.

PPi Information


(Click to view network : Source STRING)      View   

No matching records from HPRD source could be found.

Pathway Information


No matching records could be found.

Structure Information


No matching records could be found.

Domain Information




ID Location Description
cd1352923-355  PBP2_transferrin
cl2145623-355  Periplasmic_Binding_Protein_Type_2 superfamily
cd13529367-704  PBP2_transferrin
cl21456367-704  Periplasmic_Binding_Protein_Type_2 superfamily
cd1361823-355  PBP2_transferrin_N
cd13617367-701  PBP2_transferrin_C
cd1361723-355  PBP2_transferrin_C
cd13618367-704  PBP2_transferrin_N
pfam12974389-504  Phosphonate-bd
cd0107164-151  PBP2_PhnD_like
pfam1297458-151  Phosphonate-bd
cd01071445-503  PBP2_PhnD_like
cd1357164-151  PBP2_PnhD_1
TIGR0343183-169  PhnD
pfam0040523-357  Transferrin
smart00094367-706  TR_FER
smart0009423-355  TR_FER
pfam00405367-704  Transferrin
COG3221445-511  PhnD


Ontology Information


   
HPRD ID6806
Molecular ClassUnclassified
Molecular FunctionOxidoreductase activity (GO:0016491)
Biological ProcessMetabolism (GO:0008152); Energy pathways (GO:0006091)  



SNP Information


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Drug Information


No matching records could be found.

External Links


                                 
ArrayExpressGO
ICGCGO
Cancer3DGO
COSMICGO
NCGGO
TSGeneGO
Tumor Gene Family of DatabasesGO
CCDBGO
G2SBCGO
Osteosarcoma DatabaseGO
RCDBGO