CoReCG

Search results:

General Information

Gene_Symbol	Gene_ID	Gene_Name	Chromosome	Alias
MMP10	4319	Matrix metallopeptidase 10 (stromelysin 2)	11	SL-2; STMY2

Evidence
Gene
mRNA
CDS
Protein
PTM
Enzyme
PPi
Pathway
Structural
Domain
Ontology
SNP
Drug
External Links

Evidence Information

Pubmed ID	Year	Sample Information	Techniques	Mechanism	Fold Change	Remark
22930170	2012	Cell line : KM12C, KM 12SM, HT 29 Source : ATCC Sample Type : - No. of Sample : - Stage : -	Microarray analysis,Real time RT-PCR and Flow cytometry	Up-regulation	-	Gene differentially expressed and analysed bye by Microarray.

Gene Details

Chromosome: 11; NC_000011.9 (102641233..102651359, complement)
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Gene Type	protein coding
Gene Family	-
Description	Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades proteoglycans and fibronectin. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. [provided by RefSeq, Jul 2008]
Chromosome	11
Location	11q22.3
Start	102770502
End	102780628
Strand	+
Gene Sequence	>gi\|568815587:c102780628-102770502 Homo sapiens chromosome 11, GRCh38.p2 Primary Assembly AGAAGCCCAGTAGACAAAGAAGGTAAGGGCAGTGAGAATGATGCATCTTGCATTCCTTGTGCTGTTGTGT CTGCCAGTCTGCTCTGCCTATCCTCTGAGTGGGGCAGCAAAAGAGGAGGACTCCAACAAGGATCTTGCCC AGGTAATTAACGGTGGCATCTATTGCAGCTACTGGCCAGCTCAATTGTGTCTACTTGGTCTTCCAATACA AAGCAGAATGATTAGACTAGAGATCACTTTGTTAGAAAACTGTAGCATCAGAGAATAATTAACAGGCTGG AGGTGGAAATTATTTTTATGTTAACAGAGAAGAAAAGAAAGGTTCAGAAAGGGAATATAACTGCTCAAGG TTACAATAAAATAGTAGCAGTATATTTGTGGCTAAGTGAAAAGAACATATGGAGAATATATGAAACTCCT CTGGCTTTAGAATTTATTTAGTTAAAATTATTGGGGAGGGGAGCATGCTAAGTTTGATCTTTAAATCATA TCAGGTAATAGTTTTCATATTTTTACTTGTCATATTTGGACAAAAGAGTTTACCACACTTCAGTCTTAAA CCAGGTCTATAATAACAATGTAAGTAGAAAAGGTTAGTATTCTAACTTTTCACAAAACTATGTTAAAAGA GGGTTTCTTTAAAAACTAACAAAAATAATGCTAGACTTGAATTTTCAATCCCCAATTCCTTACTTGACTA GCAAACTAACATTGCAATAAAATTTAAAAATTTGTATGAAATGGGGAGTCTTAATGAAAAATCAAATTAA ATGTGATAGCCTCTTTTGTTTTAAGAAACTAGAGGAAAATTACGATGGATTATAAAAGTTGGATAAATGA TGGAAAATCACAAAAATGCCCTAAAAATTCTATTTTCCATTAGCAATACCTAGAAAAGTACTACAACCTC GAAAAGGATGTGAAACAGTTTAGAAGAAAGGACAGTAATCTCATTGTTAAAAAAATCCAAGGAATGCAGA AGTTCCTTGGGTTGGAGGTGACAGGGAAGCTAGACACTGACACTCTGGAGGTGATGCGCAAGCCCAGGTG TGGAGTTCCTGACGTTGGTCACTTCAGCTCCTTTCCTGGCATGCCGAAGTGGAGGAAAACCCACCTTACA TACAGGTAATGGTTCAGATTAGTTTTCACATAATATTGAAACCTTATAAGTTACTCGTCATATTTGGATA AGTAACATAAAGTTTTCTTTAACAATTTTTCATAAAGGCAGGAGAAAATAACATCCTCTTCAATTTTTCT CCTCCAGGATTGTGAATTATACACCAGATTTGCCAAGAGATGCTGTTGATTCTGCCATTGAGAAAGCTCT GAAAGTCTGGGAAGAGGTGACTCCACTCACATTCTCCAGGCTGTATGAAGGAGAGGCTGATATAATGATC TCTTTTGCAGTTAAAGGTAATCAAATAAAGCATCCATTTATCTGGTGTATTCATCTGTTCAGACTGCTAT AGCAAGTTACCTTAGACTGGGTAATTTATAAACAACAGAAATTTATTGCTCACAATTCTGGAGGCTGGGA AGTCCAAGATTAAGGTGCCAGCAGATTTAGTGTCTGATGAGAGCCTATTCCTCATAGATGGTACCTTCTG TGTCCTCACACGATAGAAAGGGCCAGGAGGTTCCCTCAAGCTTCTTTCATAAAAGCACTAATCTCATTCA TGAGGGCAGAGCACTTACGACATAATCACTTCCTAAAGACCTAACCTCTTAATACTATATTTCATTGGGC ATTGAGTTTCAACATATGAATTTGCAGCAGACACCAACATTCAGACTATAGAATCTACTGTTGTTTAATT GGAACAGGGTAAAAAGAAATTCTGAACACTTATATTTCCATTAATTTGTTCCCTATCAGAACATGGAGAC TTTTACTCTTTTGATGGCCCAGGACACAGTTTGGCTCATGCCTACCCACCTGGACCTGGGCTTTATGGAG ATATTCACTTTGATGATGATGAAAAATGGACAGAAGATGCATCAGGTGGGTCGTAAACCTCTCGGGAACA TTTCAGGAATAATGTCCAATCCTACCCAAAAATAATTGGATTATCTAGAACGAGCAATAAATCGAATATA CTAGTAACTGAATTTTTTTATTACCTGAGTTTTAAACAGAAGTACTGTTTGTTTCAATCATTATTGAAGA ATTTTATAAAATGTCTGTATTTTCATGTTTGCCCCCACCAAGTACAATATTGTAAAAACCATTCAACCTC ATCTCCACAACTCAGGATCTTGTGGGGGTTTGAGGATCAGCATAATTAATAATGTTTTTCATCACTTTAA TGATAGATGATTAGGATAGAATGAATTCCATTAAACCAGTTCCAATCCTAACATTTGCCCTCAGGTTTTC TTTCTTTCTTCTCATTGGCCTCCTTTTTACTTAAAAGTAGAGATCAGGAGAAAATGCCAGGAACTGAAAA AAAACTGTTAGGTCATCTTTTCGAATAAACATGTCACTGTCTCTAGCTTAGATGGGTTTTTTTCGCCCTA AATTGGCTTGGAAACACTTTACATCTAAACATAATGACTAAAATTAACTGTATGCTATTTAATTTTTAAA ATGGCTTCTGAAGTTTAGAAACACACTGTTGAAATAATCACTATTTCTGACAGTGCCTGGGATTTTTAAT GTAAATGCAAAGAACATCTTTCCTGAGTACAAGACTCAGGAGGCTGAGGCACGAGAATCACTGAACCCAG GAGATGGAGGCTGCAGTGAGCCGAGATTGTACCACTGTACTCCAGCCTGGGCAACAGAGTGAGACTCTGT CTCACGAGACTGAAGTTTGTGTTGCATGAAATGATTGCCTTTTATTTGAACAACTGTTCTTTTCTGCACA ATTCTTGGAGCCTTGGTTAAATAATATCTACTACTAAATTCAATAAAACCCTTTTTATAATATTTTTAAA AAGCTGAATCTAGCTGTGTTTGTGCTGCAGAAAACTGTTATTGGGCATGTTTCTGTTTTAAACTAAAGAT TGTACACATCCAATGGCACCTATTACTGGGAAGATTTTTGACAATCAAAAATTATTTGATTATGGCCAGG CACCAGTGGCTAATGCCTGTAATCCCAGCATTTTGGGAGGCCAAGTTGGGTGAATCACTTGAGACCAGGA GTTTGAGACCAGCCTAGCCAACATGGTGAAACCTTATCTCAACAAAAATACAAAAATTAGCCGGGCATGG TAGCACGTGCCTGTAATCACAGCTACTCAGGAGGCTGAGGCACGAGAATCGCTTGGACACATACTCCAGC CTGGGCGACAGAATGAGACTCTGTCTCAAAAAAAAAAATTACTTGAGTATGATGAAGAGGAGGAAGAGAA AATCAGACTAAACCCCACAAGAAATAACCACAGTCTTCTGGCTTAAAAGTTTGAACGTAAATGTTATATG ATTAATTTTAACCAAGGTTGCAACTGGCAAGTGTTCCTAAATTTGAACAATGACTTTTTATTTTTAGACA ACGAAGAGTTATATTTACTGACATGCTATTAGTCTTGTCCTTTCAAAAAAAAATCTTTTGAAAATAATGC TTCTCATTTGTCAATATAGGAAAAGTGTCTTAGTTTTCCTGACCAAGGAGGGATCTAGGGAGGGATACGG TGAAAAACTGTCTTATATATTGACTTAAAGTCAACCTTGAAAAACACATTAATTTCTATAAAGTATGGAA TGTGCCAATCAATGAACCAATCCACAAATACTGAAAAGACATTGTGGTTTCAAGGATGGCCTGTACAGCT GGCATATGTTCTGTATGTGTATTTATGGAAGAAAGAGCTGGTGAATTCTGAACATTTATGATTTTCATAC AGGCACCAATTTATTCCTCGTTGCTGCTCATGAACTTGGCCACTCCCTGGGGCTCTTTCACTCAGCCAAC ACTGAAGCTTTGATGTACCCACTCTACAACTCATTCACAGAGCTCGCCCAGTTCCGCCTTTCGCAAGATG ATGTGAATGGCATTCAGTCTCTCTACGGTGAGTGATGCTGGAAAAATTAGGCATTGCAGATCTACAATGA CAGTCCTCCAGAAAGCTTTCCAGTGCTACCTAAAGTATTTCTGATTTGGCCTGAAGCACTTTGAGAATGT TTGAAAGGCACACAAATTGACAGATGCATCACATTTTTTTTTAATGTTTGCATCCCCAAATCTGTTTCCT TTAGGACCTCCCCCTGCCTCTACTGAGGAACCCCTGGTGCCCACAAAATCTGTTCCTTCGGGATCTGAGA TGCCAGCCAAGTGTGATCCTGCTTTGTCCTTCGATGCCATCAGCACTCTGAGGGGAGAATATCTGTTCTT TAAAGACAGGTCAGACCAGAAAATTATATTTTCCTATCTATTCTTTTGATGTACAGTGCTTAGAAAGAAA AACAGAAACTTGACAGAGCTTTTTTTTTAATTTTAGGTTCAGGGGTACATGTGCAGGTTTGTTATATAGA TAAACTCGTGTCACAGGGGTTTGTTGTACAGATAATTTTGTCACCCCAGTACTAATCCTAGTACCCAGTA GTTACTTTTTCTGCTTGACAGAGATTTTTTAAAATATAAAATTTCCTCTACATTTTAAAATCATTCAGAT CTAGTTCTTGCTGAATTTTTAACATCTTCTTAGAATTGTCCAGATCATTTTTTACAGACTTATAAGGGAT GATTCTTGGTCCCTAGACTGTAAGTTTGATTAAGGCAGGGAGTTATATCTGTTTCGTTCATTTTTTTAAA ATATCATATATCATGGAACTTCTTCAGAAAGCACTGGTGGATCCTTAGAAGCAGGGTGGTATCTTTCCAT TTACTAATATATGCTACTATTTAAATTAATTACTTTTGGAAAAAAGTGATATGTGCTTGTGGCACAATAT TTAAACACTACCAAAAGATACGGAGTTAAAAAATCTCTCTCCAGTCTTTGGCCTACCGTCCTCCAGCTCC CTTCATATGTGCAACCACTGCTACCAATTTCCTTTGACTCTTTACAAAAATGTTCTACTCATATACAAGC ATCAATATACACATAATATTTTTTAAAATATTAGGACATAATATGCACACTGTTTATGGACTTTTAGAAT GGAACCAAGCTAAATAATTTTACTGGAACCAGTCACAAGTCCTGCCATCGATTTCATTACCCTGGAATCA CATGCAGGAGGATGGTTTAATACAGACTTCTATGAATGGGTGAATTAGCATGGATTTAAAAAAAAAGAAT TTTTTTTTCACATATCTAAAAGAGAAAGACAATTGCAAGTAATTTTATGTATTACAGATATTTTTGGCGA AGATCCCACTGGAACCCTGAACCTGAATTTCATTTGATTTCTGCATTTTGGCCCTCTCTTCCATCATATT TGGATGCTGCATATGAAGTTAACAGCAGGGACACCGTTTTTATTTTTAAAGGTGAGTACTATATAAGAAT TTCAACTTGCTGGAATAAATCCTATTGCAAAAATTTTATTGACATGAGTTTTATCCATTATATTAAAGTT TAGATTACTGAAAGACCTTGTGCTAACACTTAAATAAAATTTGTACAAAGAACATTATAAACTTTATTTT AGAGACCTCTTAAGAAAATAGGTGGCATTCCATATTCATAAAAAATGCAAGATAGTAAAAATGTCAATTT ATCTATAGATACAAGACATTTTCATTTCAAATACCAAATGCCAAAAGATTTTTCATGGAACTTGACAAAT TAGTTTTACAATTTATATGGCAGAGGAAAGGCCAAGAATAGCCAGGATGCTCCTGGTGAACCCATCTTAT TAGATGAGGAGAAAAGCCCTGTGTTATAAAACTTTAATCGGTAAGATGTAGTATCAGTGCAGGGAGAGAT AAATTAACTAATGGAGATATTCAGGTATAGAGGCTTCTTTATCAGACTTTTAAACTACTGTTTCAATTTG TTTTATTGGTAATATGCTATTAGAGTTTCTATTACTTCTTGAGTCAGTTTTGTTAACATGTTTTTCTAAA AATTTGCCAATTTTGTCTGTTTTCAAATCCATCAGAAAAAGTTTTTGGAAAATTATTTTGTTGTAATTTG AATTATTGCTGAAGTTTTGTTTTCTTTTTCATTCTTAATACTGAATCCTTTTGCCTTTCTCTTTTTTCTT CATCAATCTCATAATATATGTAATAATTTTACTGATCTTTTCAAAGGACTGACTTTTGGCTTTATTTACT CTCTATATTATATTTTGATTTCCCGTTTAATTAGTTTCTGTTCATATCTTTATTGTTGCCTTAATTTTTG TTTACTTTGAATTGATCCTGTTATTATTGTTATAGCTTAAGTTTGATACTTACCTTATTAACTTGTAACT TTTTTCTTTTCTAATACAAGCATTTATACCTATAAATAACCATTTCTTCTGTTTCATCCAGCAAATTTCG ATATGCAGTATTTTCATTTTGTTCAATTTTAATTCTTTAATTTCTCATTTTTATTTTTTCCCTAGACTCA TAGGTGATAATGGAATATTTTTAAATGTCAAGCTTTATGGAGATTTTAAAAATATTTATTTCTGGCAATC TCACTTATGTGAAGATCAAATGAATGTGAAATTGCAGTAGAAATTGTAAAGGATTACATAACTCTAACGT ATTGTTATCAAGTAATGTATCTCACATTTACATATCACTTGCACTGTGTCAGACGCCATTCTCATTGGTG GAGGTCAGGACTGAAAAGGGCTCATATTCTAGAAGGGGCAGCAGAGATGAAGCCTTTGGCAGCCTACATA TGACAAGTGCTGGGACTGAGAGAAGGAAGGGTGCCATGGGAGCACCTGACTCATACCCAGGACTCAGCAA AGATCCCTTAGGGGAGGTGATGTTAGGATGGGTCTTAAAGTTCTCTATTGTTGTGCAGAGATGGGCTGGG TGTACAGAAAGTAGAAAGGTCTTTAAGAAAGAAGAAATTGTTTTTACCAAGTAAGAGCATATCTGGAACT GCTCAGACAGATACAAGTCATTCGGTTCAGACGAAGCAAGAGAGATAAACAACAGATGGACATTTTAGAT TAGTGAATCTGGCAGTGAGTGCGAAGAAGGAATTCAGGCTTGGGGTCTGGGAGAGTGATGTAACAAAGTA AATGCAGAGAGATTGATGGGATTTTATTGTCCTAACTCACTAGAATTTGAATGAATTCCGATAGTGTTCA CAAGAAGCACAGATTGGAATTGGTGACTGTGAAATATCTCAAAGGAAGTGTCCAATAAGCAACTGATCTA TTGGTATGAAACTTAAGAGAGAGAGGTCTAGGTGAGAAATTCAGGTTAAAAGTTTACCAACAATTATAAG AAATAACTAAAACTGATCTATAAATAAACTATAACATATAGATACAAATATATAAGACACAGAAAGGGCA GTGAATCAGAGTTATCTACTCATTTATTCATTCATTCATTCACTCGCTCATTCAGGGAGTATTTATTAAG GACTGGCTGTGAACTGGACATTATTAGGTTGGAATTAAAACCAAGCCTTCCTCTTTACCACAACAATGCA CTATAATTATTTTTAAAATCAATGGCTTCAAGTAAAATGTCTTGGATTTATTTTTTCAATAGGAAATGAG TTCTGGGCCATCAGAGGAAATGAGGTACAAGCAGGTTATCCAAGAGGCATCCATACCCTGGGTTTTCCTC CAACCATAAGGAAAATTGATGCAGCTGTTTCTGACAAGGAAAAGAAGAAAACATACTTCTTTGCAGCGGA CAAATACTGGAGGTGAGATGCAAGAGAAATGACTTTCTATGAAGCCTGATTAAGAAAATTATTTTCTTTC TTTAAGGATATTTCCCTACCCTACACCCACCCTCTAACTTTCTCTAACTTCAAAATTTATGATTATGAGG AAGACAGCTTATTGTTCTACCTTCCGGATACAAAGGCCTCTCAGAATGGTGATCACTGGGCCATATACTC AGACACTAAAAGACATCAGGAGAGGCCAGCTGAGGTCCAAAGGCATTCACCTCTTATTCCATTTCCAGTC ACCATGTGGCTGCCATAGGAAGCCCAGGTGTGGCAGGCTTTGGAGACAGGATCTACAGGGTCCCAGTGTG ACTGAGAACCAGAGGTTTATTTTTAGCTAAGTGATTTAATTAATTTTGCATTATGAATTCATTATGTCTA CACAGTCTTTATGTATTTATAGTAGACACAGGGAAATTTGGTTTCTGTGTGTCCAGGCTTAGAAAATTTA CCTCAGACATATGTATGGAACCTCTGTAAAATGGCATAATGTTCCTGTTTCTGGAAAATATTGTTTTATG TGTTAAACTTGTAAGCCCAGGAAAGTAACCTATTCTTGTAGCTCTAAAAATGTTTAACACTTTTTTACAC AACTTAAAAAGTTTGTCTAGGATTCCACACTGGAAAATTAACATCACATTATACTATTGTGTGTAATGGG ACTACTGCACATCATTGAACTGTATTTCTTTCATTTGGTTTAGATTTGATGAAAATAGCCAGTCCATGGA GCAAGGCTTCCCTAGACTAATAGCTGATGACTTTCCAGGAGTTGAGCCTAAGGTTGATGCTGTATTACAG GCATTTGGTAAGAAGACCCTTATTTCATTGTCATGCAGGAATCTCCAGGCATTTTTATGATTTCAAAATA AAGTGCAGAATCAAAACAGTTTTTAAATCATTCAGTCTGATATCTTTTTTACTCCAAATTCCTGAAAATC TTAACTTTCCAATTTATGCAAAGTGGGTTTAAATTTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTTTTC CTGAATAACTTCCTAGTCTCTGTTTCATATCCGCACATAAAATCAAAGGATACTTCCTCACACAGAAGCC ATTATCTTTCAGGTCACTATGTTGGTATAAAAATACAATCTGTGTGAGCCAGGCTTACTGATGGCTGGTT GTCATTCTACTCTATCCCATCCTGTTGTCCCTTTTCTTCTATCCCACCCCAGGGGAGCCTTGTCTGGGCT TCTGTTGCAGTCTGCGATTGCCTGCATTAGTCATTTGTAAATAAAATACTAGTCCTCCCATATGCTCAAA ATAGGTCAAATGTGATTCCTGGTAATGGGCAAATAGGAAAGCAAAACTTGTTCTTGATTACTCTGAAGGA ATTTTGGAGGGAGCTGCCAGTGCTTGACAATCCAATGGTCATGAGGCTGATGATCTTGTTACTAAAATGA CTTAACCATGATGGATGCAAAGCAGGAAATGGACCTCTGGCTCATTTATCATTTGTCTGATTCTCTTGGG TCTAGTTGTCTCCCAAACTGTAATTTAGAACCTAGCAGAAGAGGGGAGGTTGGAAAGAAAGTAAAACAAG GTTTTAAAATATTATAGAATTTTATCTCTTTAGAACCAGTATGACGTAATGTTTTAGAGCACTTCCTTTG GAGTCAGATGAGATGGAGTCCTCCCTCCTTCCTTCCTTACAGATGCTACCTTGTTAAAATTACAAAACCG TCTTAATTTTTAGTTTTGTTCTCATTAATAACACATCACAGTTTTTTGTAAGGGTAATTGAGATAAAGCA TGTAAAGCACTTAGCTCAGTGCTTGGCATAGAGTAATCACTTAATAAATGCCCTCCATTATTAACTTGTA CTTAATCTAAGTTATATGTGTTGCAAAATGACATATTTGAAGATGTCTCATCATTTTCCTTATCTATATT TACAGGATTTTTCTACTTCTTCAGTGGATCATCACAGTTTGAGTTTGACCCCAATGCCAGGATGGTGACA CACATATTAAAGAGTAACAGCTGGTTACATTGCTAGGCGAGATAGGGGGAAGACAGATATGGGTGTTTTT AATAAATCTAATAATTATTCATCTAATGTATTATGAGCCAAAATGGTTAATTTTTCCTGCATGTTCTGTG ACTGAAGAAGATGAGCCTTGCAGATATCTGCATGTGTCATGAAGAATGTTTCTGGAATTCTTCACTTGCT TTTGAATTGCACTGAACAGAATTAAGAAATACTCATGTGCAATAGGTGAGAGAATGTATTTTCATAGATG TGTTATTACTTCCTCAATAAAAAGTTTTATTTTGGGCCTGTTCCTTA Download Select all
Length	10127
OMIM ID	185260
HGNC ID	HGNC:7156
Unigene ID	Hs.2258
Ensembl ID	ENSG00000166670
PharmGKB ID	-

mRNA Information

mRNA ID	NM_002425.2
Exon	join(1..142,884..1125,1268..1416,1880..2005,3853..4017, 4205..4349,5308..5441,7623..7782,8514..8617,9736..10127)
mRNA Sequence	>4319 AGAAGCCCAGTAGACAAAGAAGGTAAGGGCAGTGAGAATGATGCATCTTGCATTCCTTGTGCTG TTGTGTCTGCCAGTCTGCTCTGCCTATCCTCTGAGTGGGGCAGCAAAAGAGGAGGACTCCAACA AGGATCTTGCCCAGCAATACCTAGAAAAGTACTACAACCTCGAAAAGGATGTGAAACAGTTTAG AAGAAAGGACAGTAATCTCATTGTTAAAAAAATCCAAGGAATGCAGAAGTTCCTTGGGTTGGAG GTGACAGGGAAGCTAGACACTGACACTCTGGAGGTGATGCGCAAGCCCAGGTGTGGAGTTCCTG ACGTTGGTCACTTCAGCTCCTTTCCTGGCATGCCGAAGTGGAGGAAAACCCACCTTACATACAG GATTGTGAATTATACACCAGATTTGCCAAGAGATGCTGTTGATTCTGCCATTGAGAAAGCTCTG AAAGTCTGGGAAGAGGTGACTCCACTCACATTCTCCAGGCTGTATGAAGGAGAGGCTGATATAA TGATCTCTTTTGCAGTTAAAGAACATGGAGACTTTTACTCTTTTGATGGCCCAGGACACAGTTT GGCTCATGCCTACCCACCTGGACCTGGGCTTTATGGAGATATTCACTTTGATGATGATGAAAAA TGGACAGAAGATGCATCAGGCACCAATTTATTCCTCGTTGCTGCTCATGAACTTGGCCACTCCC TGGGGCTCTTTCACTCAGCCAACACTGAAGCTTTGATGTACCCACTCTACAACTCATTCACAGA GCTCGCCCAGTTCCGCCTTTCGCAAGATGATGTGAATGGCATTCAGTCTCTCTACGGACCTCCC CCTGCCTCTACTGAGGAACCCCTGGTGCCCACAAAATCTGTTCCTTCGGGATCTGAGATGCCAG CCAAGTGTGATCCTGCTTTGTCCTTCGATGCCATCAGCACTCTGAGGGGAGAATATCTGTTCTT TAAAGACAGATATTTTTGGCGAAGATCCCACTGGAACCCTGAACCTGAATTTCATTTGATTTCT GCATTTTGGCCCTCTCTTCCATCATATTTGGATGCTGCATATGAAGTTAACAGCAGGGACACCG TTTTTATTTTTAAAGGAAATGAGTTCTGGGCCATCAGAGGAAATGAGGTACAAGCAGGTTATCC AAGAGGCATCCATACCCTGGGTTTTCCTCCAACCATAAGGAAAATTGATGCAGCTGTTTCTGAC AAGGAAAAGAAGAAAACATACTTCTTTGCAGCGGACAAATACTGGAGATTTGATGAAAATAGCC AGTCCATGGAGCAAGGCTTCCCTAGACTAATAGCTGATGACTTTCCAGGAGTTGAGCCTAAGGT TGATGCTGTATTACAGGCATTTGGATTTTTCTACTTCTTCAGTGGATCATCACAGTTTGAGTTT GACCCCAATGCCAGGATGGTGACACACATATTAAAGAGTAACAGCTGGTTACATTGCTAGGCGA GATAGGGGGAAGACAGATATGGGTGTTTTTAATAAATCTAATAATTATTCATCTAATGTATTAT GAGCCAAAATGGTTAATTTTTCCTGCATGTTCTGTGACTGAAGAAGATGAGCCTTGCAGATATC TGCATGTGTCATGAAGAATGTTTCTGGAATTCTTCACTTGCTTTTGAATTGCACTGAACAGAAT TAAGAAATACTCATGTGCAATAGGTGAGAGAATGTATTTTCATAGATGTGTTATTACTTCCTCA ATAAAAAGTTTTATTTTGGGCCTGTTCCTTAAAAAAAAAAAAAAAAAAA Download Select all
Length	1777

CDS Information

Location	join(38..142,884..1125,1268..1416,1880..2005,3853..4017, 4205..4349,5308..5441,7623..7782,8514..8617,9736..9836)
CDS Sequence	>gi\|296080749:38-1468 Homo sapiens matrix metallopeptidase 10 (stromelysin 2) (MMP10), mRNA ATGATGCATCTTGCATTCCTTGTGCTGTTGTGTCTGCCAGTCTGCTCTGCCTATCCTCTGAGTGGGGCAG CAAAAGAGGAGGACTCCAACAAGGATCTTGCCCAGCAATACCTAGAAAAGTACTACAACCTCGAAAAGGA TGTGAAACAGTTTAGAAGAAAGGACAGTAATCTCATTGTTAAAAAAATCCAAGGAATGCAGAAGTTCCTT GGGTTGGAGGTGACAGGGAAGCTAGACACTGACACTCTGGAGGTGATGCGCAAGCCCAGGTGTGGAGTTC CTGACGTTGGTCACTTCAGCTCCTTTCCTGGCATGCCGAAGTGGAGGAAAACCCACCTTACATACAGGAT TGTGAATTATACACCAGATTTGCCAAGAGATGCTGTTGATTCTGCCATTGAGAAAGCTCTGAAAGTCTGG GAAGAGGTGACTCCACTCACATTCTCCAGGCTGTATGAAGGAGAGGCTGATATAATGATCTCTTTTGCAG TTAAAGAACATGGAGACTTTTACTCTTTTGATGGCCCAGGACACAGTTTGGCTCATGCCTACCCACCTGG ACCTGGGCTTTATGGAGATATTCACTTTGATGATGATGAAAAATGGACAGAAGATGCATCAGGCACCAAT TTATTCCTCGTTGCTGCTCATGAACTTGGCCACTCCCTGGGGCTCTTTCACTCAGCCAACACTGAAGCTT TGATGTACCCACTCTACAACTCATTCACAGAGCTCGCCCAGTTCCGCCTTTCGCAAGATGATGTGAATGG CATTCAGTCTCTCTACGGACCTCCCCCTGCCTCTACTGAGGAACCCCTGGTGCCCACAAAATCTGTTCCT TCGGGATCTGAGATGCCAGCCAAGTGTGATCCTGCTTTGTCCTTCGATGCCATCAGCACTCTGAGGGGAG AATATCTGTTCTTTAAAGACAGATATTTTTGGCGAAGATCCCACTGGAACCCTGAACCTGAATTTCATTT GATTTCTGCATTTTGGCCCTCTCTTCCATCATATTTGGATGCTGCATATGAAGTTAACAGCAGGGACACC GTTTTTATTTTTAAAGGAAATGAGTTCTGGGCCATCAGAGGAAATGAGGTACAAGCAGGTTATCCAAGAG GCATCCATACCCTGGGTTTTCCTCCAACCATAAGGAAAATTGATGCAGCTGTTTCTGACAAGGAAAAGAA GAAAACATACTTCTTTGCAGCGGACAAATACTGGAGATTTGATGAAAATAGCCAGTCCATGGAGCAAGGC TTCCCTAGACTAATAGCTGATGACTTTCCAGGAGTTGAGCCTAAGGTTGATGCTGTATTACAGGCATTTG GATTTTTCTACTTCTTCAGTGGATCATCACAGTTTGAGTTTGACCCCAATGCCAGGATGGTGACACACAT ATTAAAGAGTAACAGCTGGTTACATTGCTAG Download Select all
CCDS ID	CCDS8321.1

Protein Information

Protein ID	NP_002416.1
Protein Name	Matrix metallopeptidase 10 (stromelysin 2)
Molecular Wt. (Da)	52308
Protein Sequence	>4319 MMHLAFLVLLCLPVCSAYPLSGAAKEEDSNKDLAQQYLEKYYNLEKDVKQFRRKDSNLIVKKIQ GMQKFLGLEVTGKLDTDTLEVMRKPRCGVPDVGHFSSFPGMPKWRKTHLTYRIVNYTPDLPRDA VDSAIEKALKVWEEVTPLTFSRLYEGEADIMISFAVKEHGDFYSFDGPGHSLAHAYPPGPGLYG DIHFDDDEKWTEDASGTNLFLVAAHELGHSLGLFHSANTEALMYPLYNSFTELAQFRLSQDDVN GIQSLYGPPPASTEEPLVPTKSVPSGSEMPAKCDPALSFDAISTLRGEYLFFKDRYFWRRSHWN PEPEFHLISAFWPSLPSYLDAAYEVNSRDTVFIFKGNEFWAIRGNEVQAGYPRGIHTLGFPPTI RKIDAAVSDKEKKKTYFFAADKYWRFDENSQSMEQGFPRLIADDFPGVEPKVDAVLQAFGFFYF FSGSSQFEFDPNARMVTHILKSNSWLHC Download Select all
Length	476
Uniprot ID	Q99626
Ensembl Protein ID	ENSP00000370408

Post-translational Modification Information (Source : HPRD)

No matching records could be found.

Enzyme Information

EC	3.4.24.22
Name	stromelysin 2 matrix metalloproteinase 10 transin 2 proteoglycanase 2
Class	Hydrolases; Acting on peptide bonds (peptidases); Metalloendopeptidases
Sysname
Substrate
Product
Reaction (IUBMB)

PPi Information

(Click to view network : Source STRING) View

Interactant Gene ID (Source: HPRD)	Gene Symbol	HPRD ID	Ref Seq ID	Technique	References
1404	HAPLN1	275	NP_001875.1	in vitro	7694569
4318	MMP9	387	NP_004985.2	in vitro	9578462

Pathway Information

No matching records could be found.

Structure Information

No matching records could be found.

Domain Information

ID	Location	Description
cd04278	107-263	ZnMc_MMP
cl00064	107-263	ZnMc superfamily
cd00094	286-476	HX
cl02471	286-476	HX superfamily
cd04277	131-263	ZnMc_serralysin_like
cd00203	113-262	ZnMc
cd04279	118-263	ZnMc_MMP_like_1
smart00120	387-434	HX
pfam00045	387-434	Hemopexin
cd04268	113-262	ZnMc_MMP_like
pfam01471	33-86	PG_binding_1
cl18368	33-86	PG_binding_1 superfamily
pfam00045	295-337	Hemopexin
pfam00045	339-382	Hemopexin
smart00120	295-337	HX
smart00120	339-382	HX
COG5549	108-265	COG5549
cd04267	203-263	ZnMc_ADAM_like
cd04269	209-227	ZnMc_adamalysin_II_like
pfam00413	107-263	Peptidase_M10
smart00235	104-264	ZnMc

Ontology Information

HPRD ID	3883
Molecular Class	Metallo protease
Molecular Function	Auxiliary transport protein activity (GO:0015457)
Biological Process	Transport (GO:0006810)

SNP Information

View SNP Geneview Report

Drug Information

Uniprot ID DrugBank ID Name Type
P09238 DB00786 Marimastat SmallMoleculeDrug

External Links

ArrayExpress GO
ICGC GO
Cancer3D GO
COSMIC GO
NCG GO
TSGene GO
Tumor Gene Family of Databases GO
CCDB GO
G2SBC GO
Osteosarcoma Database GO
RCDB GO

ArrayExpress	GO
ICGC	GO
Cancer3D	GO
COSMIC	GO
NCG	GO
TSGene	GO
Tumor Gene Family of Databases	GO
CCDB	GO
G2SBC	GO
Osteosarcoma Database	GO
RCDB	GO

CoReCG

Search results:

General Information

Evidence Information

Gene Details

mRNA Information

CDS Information

Protein Information

Post-translational Modification Information (Source : HPRD)

Enzyme Information

PPi Information

Pathway Information

Structure Information

Domain Information

Ontology Information

SNP Information

Drug Information

External Links

Important Information