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General Information
| Gene_Symbol | Gene_ID | Gene_Name | Chromosome | Alias |
|---|---|---|---|---|
| CITED1 | 4435 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1 | X | - |
- Evidence
- Gene
- mRNA
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- PPi
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Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 23746764 | 2013 | Cell line : - Source : - Sample Type : CRC tumor and normal tissues No. of Sample : 161 Stage : - | RT-PCR, Immunohistochemistry, Univariate analysis followed by a multivariate logistic regression model analysis | Up-regulation | - | The CITED1 expression is correlated with lymph node metastasis in patients with CRC. In T1 colorectal cancer patients, CITED1 has the potential ability to predict the presence of lymph node metastasis. |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | - |
| Description | This gene encodes a member of the CREB-binding protein/p300-interacting transactivator with Asp/Glu-rich C-terminal domain (CITED) family of proteins. The encoded protein, also known as melanocyte-specific gene 1, may function as a transcriptional coactivator and may play a role in pigmentation of melanocytes. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jan 2009] |
| Chromosome | X |
| Location | Xq13.1 |
| Start | 71521488 |
| End | 71527037 |
| Strand | - |
| Gene Sequence | Download Select all |
| Length | 5550 |
| OMIM ID | 300149 |
| HGNC ID | HGNC:1986 |
| Unigene ID | Hs.40403 |
| Ensembl ID | ENSG00000125931 |
| PharmGKB ID | PA26523 |
mRNA Information
| mRNA ID | NM_001144886.1 |
|---|---|
| Exon | join(1..163,4254..4378,4944..5550) | mRNA Sequence | Download Select all |
| Length | 903 |
Protein Information
| Protein ID | NP_001138358.1 |
|---|---|
| Protein Name | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1 |
| Molecular Wt. (Da) | 22434 |
| Protein Sequence | Download Select all |
| Length | 193 |
| Uniprot ID | Q9Y4K3 |
| Ensembl Protein ID | ENSP00000337853 |
Post-translational Modification Information (Source : HPRD)
| Residue | Type | site |
|---|---|---|
| S | Phosphorylation | 52 |
| T | Phosphorylation | 55 |
| S | Phosphorylation | 64 |
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
No matching records from HPRD source could be found.
Pathway Information
No matching records could be found.
Structure Information
No matching records could be found.
Ontology Information
| HPRD ID | 5594 |
|---|---|
| Molecular Class | Transcription factor |
| Molecular Function | Protein binding (GO:0005515) |
| Biological Process | Regulation of cell growth (GO:0001558) |
Drug Information
No matching records could be found.