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General Information
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
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Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 22426038 | 2012 | Cell line : - Source : General Surgery Department. Sample Type : CRC tumor and normal tissue No. of Sample : 40 Stage : - | Microarray data with loss of heterozygosity (LOH), immunohistochemistry,realtime RT-PCR, Bisulphite sequencing PCR, methylation-specific PCR, DNA sequencing | Down-regulation | - | MT1F is a putative tumor suppressor gene in colon carcinogenesis that is downregulated mainly by LOH in colon cancer tissue. |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | Metallothioneins |
| Description | - |
| Chromosome | 16 |
| Location | 16q13 |
| Start | 56700653 |
| End | 56701977 |
| Strand | - |
| Gene Sequence | Download Select all |
| Length | 1325 |
| OMIM ID | 156353 |
| HGNC ID | HGNC:7399 |
| Unigene ID | Hs.433391 |
| Ensembl ID | ENSG00000125144 |
| PharmGKB ID | PA31204 |
mRNA Information
| mRNA ID | NM_005950.2 |
|---|---|
| Exon | join(1..100,689..754,1096..1331) | mRNA Sequence | Download Select all |
| Length | 420 |
Protein Information
| Protein ID | NP_005941.1 |
|---|---|
| Protein Name | metallothionein 1G |
| Molecular Wt. (Da) | 31105 |
| Protein Sequence | Download Select all |
| Length | 61 |
| Uniprot ID | Q9UHF7 |
| Ensembl Protein ID | ENSP00000220888 |
Post-translational Modification Information (Source : HPRD)
No matching records could be found.
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
| Interactant Gene ID (Source: HPRD) | Gene Symbol | HPRD ID | Ref Seq ID | Technique | References |
|---|---|---|---|---|---|
| 6462 | SHBG | 1646 | NP_001031.2 | yeast 2-hybrid | 15862967 |
Pathway Information
| Pathway Name | Pathway ID |
|---|---|
| Mineral absorption | hsa04978 |
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| pfam00131 | May-60 | Metallothio |
| cl19543 | May-60 | Metallothio superfamily |
Ontology Information
| HPRD ID | 3229 |
|---|---|
| Molecular Class | Unclassified |
| Molecular Function | Ubiquitin-specific protease activity (GO:0004843) |
| Biological Process | Protein metabolism (GO:0019538) |
Drug Information
No matching records could be found.