Search results:
General Information
| Gene_Symbol | Gene_ID | Gene_Name | Chromosome | Alias |
|---|---|---|---|---|
| MT-CYB | 4519 | mitochondrially encoded cytochrome b | mitochondria | COB, CYTB, UQCR3 |
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 26002729 | 2015 | Cell line : CCD18Co, SW480, DLD-1, LoVo Source : - Sample Type : CRC tumor and normal tissue No. of Sample : 105 Stage : - | methylation-specific PCR, real-time PCR | Methylation | - | MT3-MMP promoter is frequently hypermethylated in CRC and that downregulation of MT3-MMP may be important for cell migration in CRC. |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | Cytochrome b genes, "Mitochondrial respiratory chain complex / Complex III" |
| Description | - |
| Chromosome | mitochondria |
| Location | mitochondr |
| Start | 14747 |
| End | 15887 |
| Strand | + |
| Gene Sequence | Download Select all |
| Length | 1141 |
| OMIM ID | 516020 |
| HGNC ID | HGNC:7427 |
| Unigene ID | - |
| Ensembl ID | ENSG00000198727 |
| PharmGKB ID | PA31234 |
Protein Information
| Protein ID | |
|---|---|
| Protein Name | mitochondrially encoded cytochrome b |
| Molecular Wt. (Da) | 165443 |
| Protein Sequence | Download Select all |
| Length | 0 |
| Uniprot ID | P49815 |
| Ensembl Protein ID | ENSP00000219476 |
Post-translational Modification Information (Source : HPRD)
No matching records could be found.
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
No matching records from HPRD source could be found.
Pathway Information
| Pathway Name | Pathway ID |
|---|---|
| Alzheimer's disease | hsa05010 |
| Cardiac muscle contraction | hsa04260 |
| Huntington's disease | hsa05016 |
| Metabolic pathways | hsa01100 |
| Non-alcoholic fatty liver disease (NAFLD) | hsa04932 |
| Oxidative phosphorylation | hsa00190 |
| Parkinson's disease | hsa05012 |
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| cd00284 | 9-206 | Cytochrome_b_N |
| cl00859 | 9-206 | Cytochrome_b_N superfamily |
| cd00290 | 207-354 | cytochrome_b_C |
| cl00193 | 207-354 | cytochrome_b_C superfamily |
| pfam13631 | 88-253 | Cytochrom_B_N_2 |
| pfam00032 | 259-359 | Cytochrom_B_C |
| PRK03735 | 33-209 | PRK03735 |
| CHL00070 | 24-209 | petB |
| PRK13476 | 247-325 | PRK13476 |
| CHL00058 | 247-325 | petD |
| pfam00033 | 36-198 | Cytochrom_B_N |
| TIGR01156 | 247-325 | cytb6/f_IV |
| MTH00100 | 1-379 | CYTB |
| MTH00119 | 1-379 | CYTB |
| MTH00131 | 1-380 | CYTB |
| MTH00074 | 1-379 | CYTB |
| MTH00191 | 4-367 | CYTB |
| MTH00034 | 3-377 | CYTB |
| MTH00156 | 11-366 | CYTB |
| MTH00145 | 1-377 | CYTB |
| MTH00016 | 1-378 | CYTB |
| MTH00022 | 3-378 | CYTB |
| MTH00053 | 4-378 | CYTB |
| MTH00224 | 3-378 | CYTB |
| MTH00033 | 4-374 | CYTB |
| MTH00086 | 19-366 | CYTB |
| COG1290 | 9-366 | QcrB |
| MTH00046 | 10-357 | CYTB |
Ontology Information
| HPRD ID | 4973 |
|---|---|
| Molecular Class | Enzyme: Oxidoreductase |
| Molecular Function | Protein threonine/tyrosine kinase activity (GO:0004712) |
| Biological Process | Cell communication (GO:0007154); Signal transduction (GO:0007165) |
Drug Information
No matching records could be found.