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General Information



Gene_Symbol Gene_ID Gene_Name Chromosome Alias
DRG1 4733 developmentally regulated GTP binding protein 1  22- 







  • Evidence
  • Gene
  • mRNA
  • CDS
  • Protein
  • PTM
  • Enzyme
  • PPi
  • Pathway
  • Structural
  • Domain
  • Ontology
  • SNP
  • Drug
  • External Links



Evidence Information


Pubmed ID Year Sample Information Techniques Mechanism Fold Change Remark
15867226   2000Cell line : SW480,HCT116, NCM460

Source : -

Sample Type : -

No. of Sample : -

Stage : -

real time RT- PCR, Northern blotting hybridization, immunohistochemistryUp-regulation-In colorectal cancer, Drg1 expression may be associated with a less aggressive, indolent colorectal cancer. High Drg1 may also be associated with relative resistance to irinotecan.


Gene Details



NC_000022.10 (31795539..31830172)

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Gene Type protein coding
Gene Family -
Description -  
Chromosome 22
Location 22q12.2
Start 31795539  
End 31830172  
Strand +  
Gene Sequence

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Length 34634  
OMIM ID 603952   
HGNC ID HGNC:3029   
Unigene ID Hs.115242   
Ensembl ID ENSG00000185721   
PharmGKB ID PA27483   

mRNA Information


mRNA ID NM_004147.3
Exon join(1..173,1068..1191,3477..3652,11460..11529, 20704..20873,23728..23858,27063..27230,27508..27630, 34320..34634)  
mRNA Sequence

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Length 1467  



CDS Information


   
Location132..1235
CDS Sequence

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CCDS ID CCDS13897.1



Protein Information


      
Protein IDNP_004138.1
Protein Namedevelopmentally regulated GTP binding protein 1
Molecular Wt. (Da)92754
Protein Sequence

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Length 367  
Uniprot IDP16662
Ensembl Protein ID ENSP00000304811  



Post-translational Modification Information (Source : HPRD)


No matching records could be found.

Enzyme Information


No matching records could be found.

PPi Information


(Click to view network : Source STRING)      View   

                              
Interactant Gene ID (Source: HPRD) Gene Symbol HPRD ID Ref Seq ID Technique References
4066LYL11046NP_005574.2in vitro8649774   
6886TAL11753NP_003180.1yeast 2-hybrid9824680   


Pathway Information


No matching records could be found.

Structure Information


No matching records could be found.

Domain Information




ID Location Description
cd0189665-297  DRG
cl2145565-297  P-loop_NTPase superfamily
cd01666291-366  TGS_DRG_C
cl00155291-366  UBQ superfamily
cd0188168-187  Obg_like
cd0189865-289  Obg
pfam0192666-183  MMR_HSR1
cd04938291-366  TGS_Obg-like
pfam02824292-366  TGS
cd01616292-366  TGS
cd0088068-285  Era_like
cd0088268-285  Ras_like_GTPase
cd0189967-273  Ygr210
cd0189771-216  NOG
pfam0242166-121  FeoB_N
cd01878206-285  HflX
cd0187969-121  FeoB
cd0189470-289  EngA1
cd0416366-289  Era
cd0189566-162  EngA2
cd1138368-154  YfjP
cd0185666-121  YlqF
cd01669302-365  TGS_Ygr210_C
cd04164210-285  trmE
pfam00009241-289  GTP_EFTU
cd0185764-122  HSR1_MMR1
cd09913112-154  EHD
COG11631-367  Rbg1
TIGR0023164-217  small_GTP
TIGR0272965-289  Obg_CgtA
COG053665-290  Obg
PRK1229965-176  obgE
PRK1229765-176  obgE
PRK1229865-290  obgE
PRK1229665-172  obgE
COG001266-362  GTP1
PRK0960266-365  PRK09602
COG037066-121  FeoB
COG108471-123  Nog1
TIGR03156206-289  GTP_HflX
COG226230-318  HflX
COG116066-289  Der
PRK0960166-165  PRK09601
TIGR0045066-155  mnmE_trmE_thdF
COG110061-166  Gem1
COG115966-304  Era
TIGR0043771-121  feoB
PTZ0025866-220  PTZ00258
TIGR0359466-161  GTPase_EngA
TIGR03594210-289  GTPase_EngA
COG116166-122  RbgA
COG116066-161  Der
PRK1549470-153  era
PRK00089237-289  era
PRK0951859-155  PRK09518
TIGR0043666-123  era
COG048666-155  MnmE
TIGR03918241-285  GTP_HydF
smart0038267-150  AAA
PRK0300363-155  PRK03003
PRK00093242-289  PRK00093
PRK0956370-122  rbgA
PRK0009366-161  PRK00093
TIGR0075060-84  lao


Ontology Information


   
HPRD ID4598
Molecular ClassUnclassified
Molecular FunctionUbiquitin-specific protease activity (GO:0004843)
Biological ProcessProtein metabolism (GO:0019538)  



SNP Information


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Drug Information


No matching records could be found.

External Links


                                 
ArrayExpressGO
ICGCGO
Cancer3DGO
COSMICGO
NCGGO
TSGeneGO
Tumor Gene Family of DatabasesGO
CCDBGO
G2SBCGO
Osteosarcoma DatabaseGO
RCDBGO