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General Information
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 21636702 | 2011 | Cell line : - Source : - Sample Type : CRC tumor and normal tissue No. of Sample : 113 colonic tissues 51 CRCs, nine adenomas, 19 NCs from CRC patients (CRC-NCs), and 34 NCs from neoplasia-free subjects (control NCs) Stage : - | Real time methylation-specific PCR | Methylation | - | - |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | - |
| Description | NPTX1 is a member of the neuronal pentraxin gene family. Neuronal pentraxin 1 is similar to the rat NP1 gene which encodes a binding protein for the snake venom toxin taipoxin. Human NPTX1 mRNA is exclusively localized to the nervous system. [provided by RefSeq, Jul 2008] |
| Chromosome | 17 |
| Location | 17q25.3 |
| Start | 78440633 |
| End | 78450404 |
| Strand | - |
| Gene Sequence | Download Select all |
| Length | 9772 |
| OMIM ID | 602367 |
| HGNC ID | HGNC:7952 |
| Unigene ID | Hs.514556 |
| Ensembl ID | - |
| PharmGKB ID | PA31738 |
mRNA Information
| mRNA ID | NM_002522.3 |
|---|---|
| Exon | join(1..602,887..1094,3161..3405,4694..4873,5571..9772) | mRNA Sequence | Download Select all |
| Length | 5437 |
Protein Information
| Protein ID | NP_002513.2 |
|---|---|
| Protein Name | neuronal pentraxin I |
| Molecular Wt. (Da) | 21098 |
| Protein Sequence | Download Select all |
| Length | 432 |
| Uniprot ID | P04628 |
| Ensembl Protein ID | ENSP00000293549 |
Post-translational Modification Information (Source : HPRD)
| Residue | Type | site |
|---|---|---|
| N | Glycosylation | 154 |
| T | Phosphorylation | 9 |
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
| Interactant Gene ID (Source: HPRD) | Gene Symbol | HPRD ID | Ref Seq ID | Technique | References |
|---|---|---|---|---|---|
| 5955 | RCN2 | 3993 | NP_002893.1 | in vitro;in vivo | 10748068 |
Pathway Information
No matching records could be found.
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| cd00152 | 226-423 | PTX |
| cl22861 | 226-423 | LamG superfamily |
| smart00159 | 222-428 | PTX |
| pfam00354 | 232-421 | Pentaxin |
| pfam13385 | 240-391 | Laminin_G_3 |
| smart00560 | 252-389 | LamGL |
| cd00110 | 240-376 | LamG |
| pfam03962 | 134-217 | Mnd1 |
| COG1196 | 52-221 | Smc |
| smart00787 | 128-224 | Spc7 |
| COG1196 | 126-223 | Smc |
Ontology Information
| HPRD ID | 1318 |
|---|---|
| Molecular Class | Transport/cargo protein |
| Molecular Function | Receptor binding (GO:0005102) |
| Biological Process | Cell communication (GO:0007154); Signal transduction (GO:0007165) |
Drug Information
No matching records could be found.