CoReCG

Search results:

General Information

Gene_Symbol	Gene_ID	Gene_Name	Chromosome	Alias
NR4A2	4929	nuclear receptor subfamily 4 group A member 2	2	NOT; RNR1; HZF-3; NURR1; TINUR

Evidence
Gene
mRNA
CDS
Protein
PTM
Enzyme
PPi
Pathway
Structural
Domain
Ontology
SNP
Drug
External Links

Evidence Information

Pubmed ID	Year	Sample Information	Techniques	Mechanism	Fold Change	Remark
23809767	2013	Cell line : - Source : - Sample Type : CRC tumor and normal tissue No. of Sample : Tissue microarrays including 51 adenoma, 14 familial adenomatous polyposis with CRC, 17 stage IV CRC with adjacent mucosa and 682 stage I-III CRC specimens. Stage : TNM stage I-III	Tissue microarrays, immunohistochemistry	Up-regulation	-	NR4A2 may be prognostic and predictive for colon cancer.

Gene Details

NC_000002.11 (157180944..157189287, complement)
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Gene Type	protein coding
Gene Family	Nuclear hormone receptors
Description	This gene encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. The encoded protein may act as a transcription factor. Mutations in this gene have been associated with disorders related to dopaminergic dysfunction, including Parkinson disease, schizophernia, and manic depression. Misregulation of this gene may be associated with rheumatoid arthritis. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]
Chromosome	2
Location	2q22-q23
Start	157180944
End	157189287
Strand	-
Gene Sequence	>gi\|568815596:c156334683-156324432 Homo sapiens chromosome 2, GRCh38.p2 Primary Assembly AAACTCTCACTTTTTCCCTTTCGTTCGCATGGAATCGCTTCTGCCCACGGGGCGCTGACGCTACCGAGCT CATGCTAATATGCTATTCTTCGCCCTCCCCTCCTCATCCCCCTACTCACACACCCTCACCCGCCACCACA ACCCGCCCCCCCCACCCACTTCCTGGTTTTATTTTTTTTCTCGCGCCCGCTAGGGCATCGCCGAGCAGCG GCGGCGGCGGCAGCAGCAGCGGCAGCCGCAACATCTGGGGGAAACTTAAGGTGGTCACGTAGGTTTCCCC GAGGCTGCGGCGCAAAAGAGCCCGCGGCTTCCTGGGGCAGCCGCAGGGCATCTGATGGCAACGCCTCCCC AGCCGCCGGCGAGCTGGGGGCAGCAGGGAGTAGGCAAAGGCGGGGCTGCAGATTAGGGTTGAGCAGCCCG GGATCCCGAATAGTTCCACGGAGCCATCGGCCGGTACTGAGAACACGAGTAGGGGGGCAAGTTGCAAAAG GGTCCCGGCTGCCTGGAAACGAGCCACACCGAGAAAGGAGGGGCGGCTGGGACGCTCTGCGCGAGTAGAA AAGCGGGGGCGGCTCCGAACTCTCCCTCCCAAGGCCCAGCCGCTGGAAGCCCCGCGGGAGAAGCCCTAGG AAGCCCTCCCAGCTCCGGCCGGGAGACGGGGAGGGGGCTTGCCCTCCGGAGCTGCGGCGTTTCCTTTGCT AGAAAGCTCCCTGCGCTCTCGGCGTGGCTAGGGGAAATGACTTGCAAAGCAGAAGCGGCGGCGACTTGGA CGGCCGCGGGGGTGGGACACGCTCCCAGAGCCAGCTCGGGCCCCTCTCCTGGCTGGGCTGTAGGCTCACA CCTTACGCTTTGCGGAGACGCTGCCCCCAATCCCCACCCGCTTCGCTTTTCTTGTCCAGTCTTTCTGGGC TCTAAGATTGAGGCTGTGATAGACCTTGTGTTTCAAACGAAGATCGATTTATTCCCTTAAAACTCGTGGA AGGGGTACGAGTTGGTGGGCACAGAGGAGTATCGAAAGTATTAGAGTTTGCAGAAGGTGGGAATCAGAGT ACCTTTCTGCAGAAGGCGCACCTGTTGCCTGCTGCTCGGCTGCATTGTCTGCGAAAGGAAAAGGGGCGAC GCTTCACTCTGACTTTTGGGGTTTCTAAAGAGCTGGGTCACGGTCACTGTCTACCCTCTCCCCTTCCTCT CCCCCCCCCCCGCAAGCACCACGTCCTCCATCGAACGTGGGCACTGCATGGAAATAAGGAAACATAGAAA AATAAGCCCTACCCCCACTCCCATTCCCTTTCAGATGGGAGTGTGGGGGGTGGGGGTGGGGTAGAGAGAG TGAGAGAGAGAGATAATTAGAATGAATATATGCCAGAAGAGGAGGAGGCCTGGGACAGGAAAAGGGAGTA AAAGGGGATGAACCGGGTAGGGAAATCCCACCCGAACTGCGTGAGCCCTCTGAGCGTCTCGTGTCATGGG ACATCTGTACGCTCTTCCGCTAAGGGGGTGACGAAGGTGGGTGGGAGAGGTTAGGGCGCTGCAAGGCACA TCCCATTCCGTGCGGCTCCAGGTGCGTACTACCTGGCCACGCCGGCCTTGCCTTCCGCCGGTGCTTTTGT TGCACCCTCCCCACATGTGAGCGGCCGAGCCGCTGCGCGGGCGCAGGGGCTTCGGGGAAAGTGAAGTGTC GCGACGCTGCGGGCTGCGCAGACCTGGGAGAGGTCACACCTCTTTCGGAAAAAAAAAAAGAAAAGAAAAA AAACACCAAAAACCACCCAAGCTGGCTACCAAGGTGAACGCAGAGCGGTTCCCACCTTAAAATCGGCCCT GCTCGTGACGTCAGGTCGGAAATATACCAAAGCGAGCGCGGGCCAGGAGTCCAGGGAGCGCGGCAGCGCG GCGATTGGGCGGCGGGCCGCTGACGCGCGCTGACGCGCGGAGACTTTAGGTGCATGTTGGCAGCGGCAGC GCAAGCCACATAAACAAAGGCACATTGGCGGCCAGGGCCAGTCCGCCCGGCGGCTCGCGCACGGCTCCGC GGTCCCTTTTGCCTGTCCAGCCGGCCGCCTGTCCCTGCTCCCTCCCTCCGTGAGGTGTCCGGGTTCCCTT CGCCCAGCTCTCCCACCCCTACCCGACCCCGGCGCCCGGGCTCCCAGAGGGAACTGCACTTCGGCAGAGT TGAATGAATGAAGACAGACGCGGAGAACTCCTAAGTGAGTAGATGCAGCCCATGCAGTTCGCCTTCTTTT ATGCTTTTTCCTTCTTTTGCACGTCTCTTCTTTCCACTTGTGTGGGACAGGTTCTCTGGAAGTGGGAGCC AGAGGCTTCTAGTGAGAGTGGGACCGAAGGATGGGGAGTGCGTGCGCGCAGTTACCGGGGGGCATTTGTT CGAACTCCGGCTTTGGCACTAGTGGGGAGTTGGCTCTCGACAGAGGTTTCCAGGCTCCTCATTGGTGGAC GTGGAAGGGAGACTCCACAGTTTGGGAGCTGAGGACTAGCCCGCGGAAATGTGCGCAAAGTTTGCTGTTA GTGAGGAATTGATTGTGGCCTGTGAACACGGAGACTCCAAGTCCTATGTATACGAGGGAAGCTGCCCACA AACTGACAGGGAGAGGAAGTTCTTCAGTTTATGCGTTGCTTGGGAACTGTGTCTCCGCGGCTGGCCAGCG CGCGATGTTTCCCGGGTATTGTTGAGTAAGGGTGGTGTTGGTAGCGTGTCCTGTTACTAAGTTGCCTGAA ATTTCTGGTTTTGACATATGCTGTCCTTGGGTTTGCGAATGTATCAGAGCGAGAATATGAATATGTAAAG AGTACAGTTATGAAACTGTGGAGCTACCAGGGGGTTAATATCCAACACAGGAATATCTCTAAGGGCTGTG GGGTTCGAGTCTCCTTTCTGCTTTTTCTGGGTAATCTTCCCCCCACCCCCACCACCACTATGAAGCAAGA TTGTGGGGGAGGGGAAAGAATAAAAAGAGAGGATACTGGCTTTCTTTTTTCATTAGTAATAAGATTGTCT GTGCTCTAGAATGTCTTCCAAGTGGGAACATCTGAAAATTGCTAGGACACAAGAATGCCTTGTTCCAGAA AGGCAGATTGTGGAAGGCATTATGGGGAAGGTGTTCATCTTGCTGTGCTGGGAAACACTTCTAATATTGG TGCCAATACCATATAAGCAGTATGTCCCCCCTCTGCAATTGACCTAAGAAGCTCCTGGAAAAGTAGATCC CCTCTTCCCACCTTGTGACCATTAAGCCTTGTGACCATTAAAGATGCTGAAAGACAAGTTTTCTGGAAAA GTGAACATCAATTTATCTGTAGCTCCAATCCCAGTGCTCTGTCAAAAGCACTTTAGAAGTGCGGATGCTT CCACTCAACTTGCCTTCTCAGTCAAGGCCTTTCTAACATTTTGTAAGGGGGAAGATTGTTTTCTCATTTT ATATTCTTGACTTCTACTTTCTTCCCCTCTACCAAAAGAAAAGGCAATTTCACCACAAGAAAAAAAAATG CAAGAGAAGGTTCCAATGCTGTATTTTCATACTCTAGTCTTCATACTCAGGTCCTGAATTAACCTAAGAT GGAAATGACCTCTCCACCTACACTGTAGCAAAGGGGCCAGTTCATTACATCATAAATGTTAAATGAGTTC ATGGACTAGCTTTCCTCTTGCAGGATCTTCTCTCTGCAAGGATTTACACAGTGCAATGGGTGGTATTTTC TGTTGTTTCAAGTCATTTCTTTTATACATTCATTTTAAGTGCTATGTTTGGTAAAGGCTTCCCACTCATT TCCAATGAGACAAACAGGGAAGGCATGGAAGGGCCTGCCTGGTGAGTCTACATATGCCCAGCTGAATCTC TGTCGGGAAGAAACCCTGAAGCTTCCTGTGTCTGTATTTCAGGGAGGAGATTGGACAGGCTGGACTCCCC ATTGCTTTTCTAAAAATCTTGGAAACTTTGTCCTTCATTGAATTACGACACTGTCCACCTTTAATTTCCT CGAAAACGCCTGTAACTCGGCTGAAGGTTAGTGCAACTTCATTTCTTTCCTTTACTCTCCAGAGCTCCCC AAACATCAAGAAACAGGACAAGGCAAACCCTGTAACTTAAGGTTTGCCCGACCCATCGCCTTCGGGAACA ACTTTCTCATTGTGAAATTCAACTTCATTTCTAGATGGTCATTTCTAGAAAGAGACTGCTGAATCTGAGC TTCAGAGAAGAGGCTCATCTGAGTGGGATGAGTGGGGGGGTATGAGGGAGATGTTTGGAAATACCCAGGA GTGTAGACCCTCAGTAGCTTTTTAGCTCTGGGTCTTTATTTGGTTAGTCTTTCCACGCCCTAAACTGTTG TTCTGCAGCATTCTCTCTCTCCTGCCTTTCCTCTCGCGCCCCTACATGCTCTCTGACTGCCGCGGGCTGC CGGTGTAGCTCCAGGTGTACCCGAGCCCGGGAGAAAGTGTTCAGTTGACCAGGCTGAGTGTGTTATCACC CTGTTTCATTTCCAGCCATGCCTTGTGTTCAGGCGCAGTATGGGTCCTCGCCTCAAGGAGCCAGCCCCGC TTCTCAGAGCTACAGTTACCACTCTTCGGGAGAATACAGCTCCGATTTCTTAACTCCAGAGTTTGTCAAG TTTAGCATGGACCTCACCAACACTGAAATCACTGCCACCACTTCTCTCCCCAGCTTCAGTACCTTTATGG ACAACTACAGCACAGGCTACGACGTCAAGCCACCTTGCTTGTACCAAATGCCCCTGTCCGGACAGCAGTC CTCCATTAAGGTAGAAGACATTCAGATGCACAACTACCAGCAACACAGCCACCTGCCCCCCCAGTCTGAG GAGATGATGCCGCACTCCGGGTCGGTTTACTACAAGCCCTCCTCGCCCCCGACGCCCACCACCCCGGGCT TCCAGGTGCAGCACAGCCCCATGTGGGACGACCCGGGATCTCTCCACAACTTCCACCAGAACTACGTGGC CACTACGCACATGATCGAGCAGAGGAAAACGCCAGTCTCCCGCCTCTCCCTCTTCTCCTTTAAGCAATCG CCCCCTGGCACCCCGGTGTCTAGTTGCCAGATGCGCTTCGACGGGCCCCTGCACGTCCCCATGAACCCGG AGCCCGCCGGCAGCCACCACGTGGTGGACGGGCAGACCTTCGCTGTGCCCAACCCCATTCGCAAGCCCGC GTCCATGGGCTTCCCGGGCCTGCAGATCGGCCACGCGTCTCAGCTGCTCGACACGCAGGTGCCCTCACCG CCGTCGCGGGGCTCCCCCTCCAACGAGGGGCTGTGCGCTGTGTGTGGGGACAACGCGGCCTGCCAACACT ACGGCGTGCGCACCTGTGAGGGCTGCAAAGGCTTCTTTAAGGTGAGCAATGGCGGGAGCGGAGTAGGCAG GTAGGGAGCCCCTAGTGCCCGGGACCTCGGAGTGTGCCCTCTGCCTTGGTGCCAGTAGCCCAGCCCCAGC TCTCCCGGGACTGCCCAGCTCTCCGGGGTCCGCCGAAGCTGCCCTGCAGGAGACCATGGGCTGCGGCGGG GACTTCCGGGTGTCTGAGAAAGGGAAGCAGAAAGACTGGGAGGCCAGGGTCGCATCCCCCTCGCATTCAG CCGACCCGGCTGGCCCCCGCCCGAAGTTGCTGGAGCCGGAGTTGGAAGAGGGTCATTTGCATGTGCTAGG AGCTGTCTTCCCTGTTCAGAATGAAATTGGTTAGGACAGAGAACCGTGTCTGAGCTAACCAAGTGGAACA GAATTCCCTATGGTCAAATTAAGTGATCTCTTTATTTCGCCATCCTGATTGAATAATCTTATCATTTTAA ATAGAGAAGGTCTCCAAGGAATGTAAATAATATGAATGCCCACGGATTTGTATTTACTGAGCGTCTCCTT CTCCTTCTCTTGGCATATAAAACACAGCAAGGAGCGGCAAGGTTAGCTCAAATGTTAACGCTATCAATTT TCTTCTGTTAAATGCCCTGGGGGAGGAAAAAAGAAAAGAAAGAAAGAAAAGGAAGAGAAAAAAATAAAAT GGAATTGTGTGTATGTGTTTGTTTGTGGGGAGGAATCGTAGACCCCAGTCACATAACAGAAATTTTCTCC GAGTTGCCTGATTTTCAAAAGAAGAAAAAAAATGTTGGTCTATATTGTCTCCTTTTGCAGCGCACAGTGC AAAAAAATGCAAAATACGTGTGTTTAGCAAATAAAAACTGCCCAGTGGACAAGCGTCGCCGGAATCGCTG TCAGTACTGCCGATTTCAGAAGTGCCTGGCTGTTGGGATGGTCAAAGAAGGTAGGCTGAGGGGAGCTGCC GACCCTCCAGTTTGCGCCTTTAGGAAACCACTGCTCATACTCCAGCATCACGTTCCACTTCCCGGTGCTG GGGATCTCCGACTCCCCCTCAGTATGGCCTCCAGGACCCTGCAGCTGCCTGCTTGCCCGGCCTTCCCTAG AGAAAGCCGCCAGGCCCTTCTCTCCTTTAACTATACGACCCATTTGGAGGAAGACATAAAATAACCCCGC ATTTTTTAATGCTTCTAGTCAGTGAAGGCTTTACAAGCACTGGGGCCCTCAGCCGCTCAGCCTGGTGCCC CGCGGCTGCGGCCTTCCCCGGGGAGGGACCGAGGCAGCAGCTGGGCCTGGGCTCGGAAAAGCGGCGCTAA CAGGGCTCTTCCTTTGCAGTGGTTCGCACAGACAGTTTAAAAGGCCGGAGAGGTCGTTTGCCCTCGAAAC CGAAGAGCCCACAGGAGCCCTCTCCCCCTTCGCCCCCGGTGAGTCTGATCAGTGCCCTCGTCAGGGCCCA TGTCGACTCCAACCCGGCTATGACCAGCCTGGACTATTCCAGGGTAAGAAGCTGGCGGGGGGGATATCAT GTGGACAAACCGACAGATGGGCAGGACCCCTCCCCACATCCGTCATTAACTCTCAGATTCAACGGGGGTA AAGAAGGCAAGCAAGGCTGTATATGCCTCGCAGCTCTGGCCAGGGCCTCAAGATTCAGATCTTCAGACAA TCCATGTAGCTGGGGGCATAGACATGAGGACAGGATGGAGGAAGGAGGAGAGGGACACGCCACAGGGTTT GAAGCTGTGTGAATTCCCACTACCCCACTACCCCATCGCCCCTCCTCTTCCATATACACCAGTGCCTCTA CCATGAAATCCAGGGGCTGTGCAAACTCTCCCCCTTCCCAATCTACTTTATTCCCAGTCCTCCATAGAGA TAGATGCTTTAATCCTCATCCTTCCTGGCACTGTGCTGGGGAAGGATGTGGGGGCCTGTCTGGGGGTCAG GGAAGGGAAGGAGAGGGTGTAAAGAATGCCAGTGGGGTGGGGGATCAAGTGGTCAGATCCTTTTTACTCC AGCTGTGAAAAATATGCGGGCTTTAATTGGAGGAAGTATGTTGAGCAAACCTGGTAGGGACTGCAATTTT ATTAAGATTTGCAAAAGGGCGTCTCAGCTCGAGGCCCACTCTGGGACTAGCATGAATACTAACATGTCAA TTGTTTTGTGGAGATAAGAGTGAACGTTTCCCAGGGCTGGATGGCACTGTATTTAGTCTGTATGGAAATG GCAATTTACATATTTAAAGCAGCGACCTCGTAGCACCATCCCTAATTGAATTAATTGCCCCGGAACATCT AATTTCCTTACTGGTCAGAGAGAGGTTTAATTGTTATAAAAACCTGGCTCCCCTATTAGAAACGGGGTTA GCAATTTCACGGGTTATATATTTTAGAGAACCTCATTAAGTGCTTTTTAAAATGAAATTCCAGTTCCAGG CGAACCCTGACTATCAAATGAGTGGAGATGACACCCAGCATATCCAGCAATTCTATGATCTCCTGACTGG CTCCATGGAGATCATCCGGGGCTGGGCAGAGAAGATCCCTGGCTTCGCAGACCTGCCCAAAGCCGACCAA GACCTGCTTTTTGAATCAGCTTTCTTAGAACTGTTTGTCCTTCGATTAGCATACAGGTAATAAGGGAGGG AGGGAGACAATCCAGGGAGGCTGTGAGAGAAATCAAGAAAGGAAAAGAAAGGGAGGAAGGGAAACCAGAG GGTGGGGTAGAGAAAAAGACAGAATAGGAAATGGAAGTCGGAGAAAGGAAGAAAAAGAAAGAAAACAAAA AAAGACGAGAAGAAGCGAGCCCAGAAGCCTTGGATGAATGGAATGGAGGTGGGATAGGGGGCGTTCTTGA TTGTTATGAAATTAAACCCTTTCAAGGTCCACTGGTCTACATTTTATTAACTCTTCAGTAATTAGGTGAC TCTTAAATCCCTCATTTATTGCTCTTCAAGTAATTAGTTGTTTAGCTTTTCTCTCTCTCTTTTTCTCCCC TCTCTCTCTTTGGTATTAATTGCAGGTCCAACCCAGTGGAGGGTAAACTCATCTTTTGCAATGGGGTGGT CTTGCACAGGTTGCAATGCGTTCGTGGCTTTGGGGAATGGATTGATTCCATTGTTGAATTCTCCTCCAAC TTGCAGAATATGAACATCGACATTTCTGCCTTCTCCTGCATTGCTGCCCTGGCTATGGTCACAGGTCAGT ACTGCAGGCGCAGGGCGCTTCCCCTCCAGAACTGCCTAGCAGGATTTGTCCTGAGTTTCCCTTGTCACAG ATTCTCCTTGGTTTTGCCAACTAGCTAACTGTCTTGTACATTCTTCTTTTGTTTCTGATTATGTTTTCTG CAGAGAGACACGGGCTCAAGGAACCCAAGAGAGTGGAAGAACTGCAAAACAAGATTGTAAATTGTCTCAA AGACCACGTGACTTTCAACAATGGGGGGTTGAACCGCCCCAATTATTTGTCCAAACTGTTGGGGAAGCTC CCAGAACTTCGTACCCTTTGCACACAGGGGCTACAGCGCATTTTCTACCTGAAATTGGAAGACTTGGTGC CACCGCCAGCAATAATTGACAAACTTTTCCTGGACACTTTACCTTTCTAAGACCTCCTCCCAAGCACTTC AAAGGAACTGGAATGATAATGGAAACTGTCAAGAGGGGGCAAGTCACATGGGCAGAGATAGCCGTGTGAG CAGTCTCAGCTCAAGCTGCCCCCCATTTCTGTAACCCTCCTAGCCCCCTTGATCCCTAAAGAAAACAAAC AAACAAACAAAAACTGTTGCTATTTCCTAACCTGCAGGCAGAACCTGAAAGGGCATTTTGGCTCCGGGGC ATCCTGGATTTAGAACATGGACTACACACAATACAGTGGTATAAACTTTTTATTCTCAGTTTAAAAATCA GTTTGTTGTTCAGAAGAAAGATTGCTATAATGTATAATGGGAAATGTTTGGCCATGCTTGGTTGTTGCAG TTCAGACAAATGTAACACACACACACATACACACACACACACACACACAGAGACACATCTTAAGGGGACC CACAAGTATTGCCCTTTAACAAGACTTCAAAGTTTTCTGCTGTAAAGAAAGCTGTAATATATAGTAAAAC TAAATGTTGCGTGGGTGGCATGAGTTGAAGAAGGCAAAGGCTTGTAAATTTACCCAATGCAGTTTGGCTT TTTAAATTATTTTGTGCCTATTTATGAATAAATATTACAAATTCTAAAAGATAAGTGTGTTTGCAAAAAA AAAGAAAATAAATACATAAAAAAGGGACAAGCATGTTGATTCTAGGTTGAAAATGTTATAGGCACTTGCT ACTTCAGTAATGTCTATATTATATAAATAGTATTTCAGACACTATGTAGTCTGTTAGATTTTATAAAGAT TGGTAGTTATCTGAGCTTAAACATTTTCTCAATTGTAAAATAGGTGGGCACAAGTATTACACATCAGAAA ATCCTGACAAAAGGGACACATAGTGTTTGTAACACCGTCCAACATTCCTTGTTTGTAAGTGTTGTATGTA CCGTTGATGTTGATAAAAAGAAAGTTTATATCTTGATTATTTTGTTGTCTAAAGCTAAACAAAACTTGCA TGCAGCAGCTTTTGACTGTTTCCAGAGTGCTTATAATATACATAACTCCCTGGAAATAACTGAGCACTTT GAATTTTTTTTATGTCTAAAATTGTCAGTTAATTTATTATTTTGTTTGAGTAAGAATTTTAATATTGCCA TATTCTGTAGTATTTTTCTTTGTATATTTCTAGTATGGCACATGATATGAGTCACTGCCTTTTTTTCTAT GGTGTATGACAGTTAGAGATGCTGATTTTTTTTCTGATAAATTCTTTCTTTGAGAAAGACAATTTTAATG TTTACAACAATAAACCATGTAAATGAACAGAA Download Select all
Length	8344
OMIM ID	601828
HGNC ID	HGNC:7981
Unigene ID	Hs.563344
Ensembl ID	ENSG00000153234
PharmGKB ID	PA31762

mRNA Information

mRNA ID	?NM_006186.3
Exon
mRNA Sequence	>gi\|767918291\|ref\|XM_006712553.2\| PREDICTED: Homo sapiens nuclear receptor subfamily 4, group A, member 2 (NR4A2), transcript variant X2, mRNA AAACTCTCACTTTTTCCCTTTCGTTCGCATGGAATCGCTTCTGCCCACGGGGCGCTGACGCTACCGAGCT CATGCTAATATGCTATTCTTCGCCCTCCCCTCCTCATCCCCCTACTCACACACCCTCACCCGCCACCACA ACCCGCCCCCCCCACCCACTTCCTGGTTTTATTTTTTTTCTCGCGCCCGCTAGGGCATCGCCGAGCAGCG GCGGCGGCGGCAGCAGCAGCGGCAGCCGCAACATCTGGGGGAAACTTAAGGTGGTCACGTAGGTTTCCCC GAGGCTGCGGCGCAAAAGAGCCCGCGGCTTCCTGGGGCAGCCGCAGGGCATCTGATGGCAACGCCTCCCC AGCCGCCGGCGAGCTGGGGGCAGCAGGGAGTAGGCAAAGGCGGGGCTGCAGATTAGGGTTGAGCAGCCCG GGATCCCGAATAGTTCCACGGAGCCATCGGCCGGTACTGAGAACACGAGTAGGGGGGCAAGTTGCAAAAG GGTCCCGGCTGCCTGGAAACGAGCCACACCGAGAAAGGAGGGGCGGCTGGGACGCTCTGCGCGAGTAGAA AAGCGGGGGCGGCTCCGAACTCTCCCTCCCAAGGCCCAGCCGCTGGAAGCCCCGCGGGAGAAGCCCTAGG AAGCCCTCCCAGCTCCGGCCGGGAGACGGGGAGGGGGCTTGCCCTCCGGAGCTGCGGCGTTTCCTTTGCT AGAAAGCTCCCTGCGCTCTCGGCGTGGCTAGGGGAAATGACTTGCAAAGCAGAAGCGGCGGCGACTTGGA CGGCCGCGGGGGTGGGACACGCTCCCAGAGCCAGCTCGGGCCCCTCTCCTGGCTGGGCTGTAGGCTCACA CCTTACGCTTTGCGGAGACGCTGCCCCCAATCCCCACCCGCTTCGCTTTTCTTGTCCAGTCTTTCTGGGC TCTAAGATTGAGGCTGTGATAGACCTTGTGTTTCAAACGAAGATCGATTTATTCCCTTAAAACTCGTGGA AGGGGTACGAGTTGGTGGGCACAGAGGAGTATCGAAAGTATTAGAGTTTGCAGAAGGTGGGAATCAGAGT ACCTTTCTGCAGAAGGCGCACCTGTTGCCTGCTGCTCGGCTGCATTGTCTGCGAAAGGAAAAGGGGCGAC GCTTCACTCTGACTTTTGGGGTTTCTAAAGAGCTGGGTCACGGTCACTGTCTACCCTCTCCCCTTCCTCT CCCCCCCCCCCGCAAGCACCACGTCCTCCATCGAACGTGGGCACTGCATGGAAATAAGGAAACATAGAAA AATAAGCCCTACCCCCACTCCCATTCCCTTTCAGATGGGAGTGTGGGGGGTGGGGGTGGGGTAGAGAGAG TGAGAGAGAGAGATAATTAGAATGAATATATGCCAGAAGAGGAGGAGGCCTGGGACAGGAAAAGGGAGTA AAAGGGGATGAACCGGGTAGGGAAATCCCACCCGAACTGCGTGAGCCCTCTGAGCGTCTCGTGTCATGGG ACATCTGTACGCTCTTCCGCTAAGGGGGTGACGAAGGTGGGTGGGAGAGGTTAGGGCGCTGCAAGGCACA TCCCATTCCGTGCGGCTCCAGGTGCGTACTACCTGGCCACGCCGGCCTTGCCTTCCGCCGGTGCTTTTGT TGCACCCTCCCCACATGTGAGCGGCCGAGCCGCTGCGCGGGCGCAGGGGCTTCGGGGAAAGTGAAGTGTC GCGACGCTGCGGGCTGCGCAGACCTGGGAGAGGTCACACCTCTTTCGGAAAAAAAAAAAGAAAAGAAAAA AAACACCAAAAACCACCCAAGCTGGCTACCAAGGTGAACGCAGAGCGGTTCCCACCTTAAAATCGGCCCT GCTCGTGACGTCAGGTCGGAAATATACCAAAGCGAGCGCGGGCCAGGAGTCCAGGGAGCGCGGCAGCGCG GCGATTGGGCGGCGGGCCGCTGACGCGCGCTGACGCGCGGAGACTTTAGGTGCATGTTGGCAGCGGCAGC GCAAGCCACATAAACAAAGGCACATTGGCGGCCAGGGCCAGTCCGCCCGGCGGCTCGCGCACGGCTCCGC GGTCCCTTTTGCCTGTCCAGCCGGCCGCCTGTCCCTGCTCCCTCCCTCCGTGAGGTGTCCGGGTTCCCTT CGCCCAGCTCTCCCACCCCTACCCGACCCCGGCGCCCGGGCTCCCAGAGGGAACTGCACTTCGGCAGAGT TGAATGAATGAAGACAGACGCGGAGAACTCCTAACCATGCCTTGTGTTCAGGCGCAGTATGGGTCCTCGC CTCAAGGAGCCAGCCCCGCTTCTCAGAGCTACAGTTACCACTCTTCGGGAGAATACAGCTCCGATTTCTT AACTCCAGAGTTTGTCAAGTTTAGCATGGACCTCACCAACACTGAAATCACTGCCACCACTTCTCTCCCC AGCTTCAGTACCTTTATGGACAACTACAGCACAGGCTACGACGTCAAGCCACCTTGCTTGTACCAAATGC CCCTGTCCGGACAGCAGTCCTCCATTAAGGTAGAAGACATTCAGATGCACAACTACCAGCAACACAGCCA CCTGCCCCCCCAGTCTGAGGAGATGATGCCGCACTCCGGGTCGGTTTACTACAAGCCCTCCTCGCCCCCG ACGCCCACCACCCCGGGCTTCCAGGTGCAGCACAGCCCCATGTGGGACGACCCGGGATCTCTCCACAACT TCCACCAGAACTACGTGGCCACTACGCACATGATCGAGCAGAGGAAAACGCCAGTCTCCCGCCTCTCCCT CTTCTCCTTTAAGCAATCGCCCCCTGGCACCCCGGTGTCTAGTTGCCAGATGCGCTTCGACGGGCCCCTG CACGTCCCCATGAACCCGGAGCCCGCCGGCAGCCACCACGTGGTGGACGGGCAGACCTTCGCTGTGCCCA ACCCCATTCGCAAGCCCGCGTCCATGGGCTTCCCGGGCCTGCAGATCGGCCACGCGTCTCAGCTGCTCGA CACGCAGGTGCCCTCACCGCCGTCGCGGGGCTCCCCCTCCAACGAGGGGCTGTGCGCTGTGTGTGGGGAC AACGCGGCCTGCCAACACTACGGCGTGCGCACCTGTGAGGGCTGCAAAGGCTTCTTTAAGCGCACAGTGC AAAAAAATGCAAAATACGTGTGTTTAGCAAATAAAAACTGCCCAGTGGACAAGCGTCGCCGGAATCGCTG TCAGTACTGCCGATTTCAGAAGTGCCTGGCTGTTGGGATGGTCAAAGAAGTGGTTCGCACAGACAGTTTA AAAGGCCGGAGAGGTCGTTTGCCCTCGAAACCGAAGAGCCCACAGGAGCCCTCTCCCCCTTCGCCCCCGT TCCAGGCGAACCCTGACTATCAAATGAGTGGAGATGACACCCAGCATATCCAGCAATTCTATGATCTCCT GACTGGCTCCATGGAGATCATCCGGGGCTGGGCAGAGAAGATCCCTGGCTTCGCAGACCTGCCCAAAGCC GACCAAGACCTGCTTTTTGAATCAGCTTTCTTAGAACTGTTTGTCCTTCGATTAGCATACAGGTCCAACC CAGTGGAGGGTAAACTCATCTTTTGCAATGGGGTGGTCTTGCACAGGTTGCAATGCGTTCGTGGCTTTGG GGAATGGATTGATTCCATTGTTGAATTCTCCTCCAACTTGCAGAATATGAACATCGACATTTCTGCCTTC TCCTGCATTGCTGCCCTGGCTATGGTCACAGAGAGACACGGGCTCAAGGAACCCAAGAGAGTGGAAGAAC TGCAAAACAAGATTGTAAATTGTCTCAAAGACCACGTGACTTTCAACAATGGGGGGTTGAACCGCCCCAA TTATTTGTCCAAACTGTTGGGGAAGCTCCCAGAACTTCGTACCCTTTGCACACAGGGGCTACAGCGCATT TTCTACCTGAAATTGGAAGACTTGGTGCCACCGCCAGCAATAATTGACAAACTTTTCCTGGACACTTTAC CTTTCTAAGACCTCCTCCCAAGCACTTCAAAGGAACTGGAATGATAATGGAAACTGTCAAGAGGGGGCAA GTCACATGGGCAGAGATAGCCGTGTGAGCAGTCTCAGCTCAAGCTGCCCCCCATTTCTGTAACCCTCCTA GCCCCCTTGATCCCTAAAGAAAACAAACAAACAAACAAAAACTGTTGCTATTTCCTAACCTGCAGGCAGA ACCTGAAAGGGCATTTTGGCTCCGGGGCATCCTGGATTTAGAACATGGACTACACACAATACAGTGGTAT AAACTTTTTATTCTCAGTTTAAAAATCAGTTTGTTGTTCAGAAGAAAGATTGCTATAATGTATAATGGGA AATGTTTGGCCATGCTTGGTTGTTGCAGTTCAGACAAATGTAACACACACACACATACACACACACACAC ACACACAGAGACACATCTTAAGGGGACCCACAAGTATTGCCCTTTAACAAGACTTCAAAGTTTTCTGCTG TAAAGAAAGCTGTAATATATAGTAAAACTAAATGTTGCGTGGGTGGCATGAGTTGAAGAAGGCAAAGGCT TGTAAATTTACCCAATGCAGTTTGGCTTTTTAAATTATTTTGTGCCTATTTATGAATAAATATTACAAAT TCTAAAAGATAAGTGTGTTTGCAAAAAAAAAGAAAATAAATACATAAAAAAGGGACAAGCATGTTGATTC TAGGTTGAAAATGTTATAGGCACTTGCTACTTCAGTAATGTCTATATTATATAAATAGTATTTCAGACAC TATGTAGTCTGTTAGATTTTATAAAGATTGGTAGTTATCTGAGCTTAAACATTTTCTCAATTGTAAAATA GGTGGGCACAAGTATTACACATCAGAAAATCCTGACAAAAGGGACACATAGTGTTTGTAACACCGTCCAA CATTCCTTGTTTGTAAGTGTTGTATGTACCGTTGATGTTGATAAAAAGAAAGTTTATATCTTGATTATTT TGTTGTCTAAAGCTAAACAAAACTTGCATGCAGCAGCTTTTGACTGTTTCCAGAGTGCTTATAATATACA TAACTCCCTGGAAATAACTGAGCACTTTGAATTTTTTTTATGTCTAAAATTGTCAGTTAATTTATTATTT TGTTTGAGTAAGAATTTTAATATTGCCATATTCTGTAGTATTTTTCTTTGTATATTTCTAGTATGGCACA TGATATGAGTCACTGCCTTTTTTTCTATGGTGTATGACAGTTAGAGATGCTGATTTTTTTTCTGATAAAT TCTTTCTTTGAGAAAGACAATTTTAATGTTTACAACAATAAACCATGTAAATGAACAGAA Download Select all
Length

CDS Information

Location
CDS Sequence	>lcl\|XM_006712553.2_cds_XP_006712616.1_1 [gene=NR4A2] [protein=nuclear receptor subfamily 4 group A member 2 isoform X2] [protein_id=XP_006712616.1] [location=2174..3928] ATGAATGAAGACAGACGCGGAGAACTCCTAACCATGCCTTGTGTTCAGGCGCAGTATGGGTCCTCGCCTC AAGGAGCCAGCCCCGCTTCTCAGAGCTACAGTTACCACTCTTCGGGAGAATACAGCTCCGATTTCTTAAC TCCAGAGTTTGTCAAGTTTAGCATGGACCTCACCAACACTGAAATCACTGCCACCACTTCTCTCCCCAGC TTCAGTACCTTTATGGACAACTACAGCACAGGCTACGACGTCAAGCCACCTTGCTTGTACCAAATGCCCC TGTCCGGACAGCAGTCCTCCATTAAGGTAGAAGACATTCAGATGCACAACTACCAGCAACACAGCCACCT GCCCCCCCAGTCTGAGGAGATGATGCCGCACTCCGGGTCGGTTTACTACAAGCCCTCCTCGCCCCCGACG CCCACCACCCCGGGCTTCCAGGTGCAGCACAGCCCCATGTGGGACGACCCGGGATCTCTCCACAACTTCC ACCAGAACTACGTGGCCACTACGCACATGATCGAGCAGAGGAAAACGCCAGTCTCCCGCCTCTCCCTCTT CTCCTTTAAGCAATCGCCCCCTGGCACCCCGGTGTCTAGTTGCCAGATGCGCTTCGACGGGCCCCTGCAC GTCCCCATGAACCCGGAGCCCGCCGGCAGCCACCACGTGGTGGACGGGCAGACCTTCGCTGTGCCCAACC CCATTCGCAAGCCCGCGTCCATGGGCTTCCCGGGCCTGCAGATCGGCCACGCGTCTCAGCTGCTCGACAC GCAGGTGCCCTCACCGCCGTCGCGGGGCTCCCCCTCCAACGAGGGGCTGTGCGCTGTGTGTGGGGACAAC GCGGCCTGCCAACACTACGGCGTGCGCACCTGTGAGGGCTGCAAAGGCTTCTTTAAGCGCACAGTGCAAA AAAATGCAAAATACGTGTGTTTAGCAAATAAAAACTGCCCAGTGGACAAGCGTCGCCGGAATCGCTGTCA GTACTGCCGATTTCAGAAGTGCCTGGCTGTTGGGATGGTCAAAGAAGTGGTTCGCACAGACAGTTTAAAA GGCCGGAGAGGTCGTTTGCCCTCGAAACCGAAGAGCCCACAGGAGCCCTCTCCCCCTTCGCCCCCGTTCC AGGCGAACCCTGACTATCAAATGAGTGGAGATGACACCCAGCATATCCAGCAATTCTATGATCTCCTGAC TGGCTCCATGGAGATCATCCGGGGCTGGGCAGAGAAGATCCCTGGCTTCGCAGACCTGCCCAAAGCCGAC CAAGACCTGCTTTTTGAATCAGCTTTCTTAGAACTGTTTGTCCTTCGATTAGCATACAGGTCCAACCCAG TGGAGGGTAAACTCATCTTTTGCAATGGGGTGGTCTTGCACAGGTTGCAATGCGTTCGTGGCTTTGGGGA ATGGATTGATTCCATTGTTGAATTCTCCTCCAACTTGCAGAATATGAACATCGACATTTCTGCCTTCTCC TGCATTGCTGCCCTGGCTATGGTCACAGAGAGACACGGGCTCAAGGAACCCAAGAGAGTGGAAGAACTGC AAAACAAGATTGTAAATTGTCTCAAAGACCACGTGACTTTCAACAATGGGGGGTTGAACCGCCCCAATTA TTTGTCCAAACTGTTGGGGAAGCTCCCAGAACTTCGTACCCTTTGCACACAGGGGCTACAGCGCATTTTC TACCTGAAATTGGAAGACTTGGTGCCACCGCCAGCAATAATTGACAAACTTTTCCTGGACACTTTACCTT TCTAA Download Select all
CCDS ID	CCDS2201.1

Protein Information

Protein ID
Protein Name	nuclear receptor subfamily 4 group A member 2
Molecular Wt. (Da)	39964
Protein Sequence	>lcl\|XM_006712553.2_prot_XP_006712616.1_1 [gene=NR4A2] [protein=nuclear receptor subfamily 4 group A member 2 isoform X2] [protein_id=XP_006712616.1] [location=2174..3928] MNEDRRGELLTMPCVQAQYGSSPQGASPASQSYSYHSSGEYSSDFLTPEFVKFSMDLTNTEITATTSLPS FSTFMDNYSTGYDVKPPCLYQMPLSGQQSSIKVEDIQMHNYQQHSHLPPQSEEMMPHSGSVYYKPSSPPT PTTPGFQVQHSPMWDDPGSLHNFHQNYVATTHMIEQRKTPVSRLSLFSFKQSPPGTPVSSCQMRFDGPLH VPMNPEPAGSHHVVDGQTFAVPNPIRKPASMGFPGLQIGHASQLLDTQVPSPPSRGSPSNEGLCAVCGDN AACQHYGVRTCEGCKGFFKRTVQKNAKYVCLANKNCPVDKRRRNRCQYCRFQKCLAVGMVKEVVRTDSLK GRRGRLPSKPKSPQEPSPPSPPFQANPDYQMSGDDTQHIQQFYDLLTGSMEIIRGWAEKIPGFADLPKAD QDLLFESAFLELFVLRLAYRSNPVEGKLIFCNGVVLHRLQCVRGFGEWIDSIVEFSSNLQNMNIDISAFS CIAALAMVTERHGLKEPKRVEELQNKIVNCLKDHVTFNNGGLNRPNYLSKLLGKLPELRTLCTQGLQRIF YLKLEDLVPPPAIIDKLFLDTLPF Download Select all
Length	0
Uniprot ID	O00744
Ensembl Protein ID	ENSP00000301061

Post-translational Modification Information (Source : HPRD)

Residue	Type	site
S	Phosphorylation	347
S	Phosphorylation	347
S	Phosphorylation	347
S	Phosphorylation	284
K	Sumoylation	577
S	Phosphorylation	181;-
S	Phosphorylation	181;-
S	Phosphorylation	181;-
S	Phosphorylation	118;-
S	Phosphorylation	356
S	Phosphorylation	359
S	Phosphorylation	356
S	Phosphorylation	359
S	Phosphorylation	356
S	Phosphorylation	359
S	Phosphorylation	293
S	Phosphorylation	296

Enzyme Information

No matching records could be found.

PPi Information

(Click to view network : Source STRING) View

Interactant Gene ID (Source: HPRD)	Gene Symbol	HPRD ID	Ref Seq ID	Technique	References
1028	CDKN1C	2913	NP_000067.1	in vitro	14671317
6256	RXRA	1577	NP_002948.1	in vitro;in vivo;yeast 2-hybrid	7 758 108 770 565 510 000 000
6257	RXRB	1578	NP_068811.1	in vitro;in vivo;yeast 2-hybrid	7 758 108 770 565 510 000 000
10987	COPS5	6888	NP_006828.2	yeast 2-hybrid	15604093
51588	PIAS4	6910	NP_056981.2	in vitro;in vivo;yeast 2-hybrid	14559918

Pathway Information

Pathway Name	Pathway ID
Aldosterone synthesis and secretion	hsa04925

Structure Information

No matching records could be found.

Domain Information

ID	Location	Description
cd07071	361-598	NR_LBD_Nurr1
cl11397	361-598	NR_LBD superfamily
cd06969	261-335	NR_DBD_NGFI-B
cl02596	261-335	NR_DBD_like superfamily
cd07348	367-598	NR_LBD_NGFI-B
cd06945	367-598	NR_LBD_Nurr1_like
cd07072	367-598	NR_LBD_DHR38_like
cd06916	263-334	NR_DBD_like
pfam00105	262-330	zf-C4
cd06157	404-565	NR_LBD
cd06961	262-345	NR_DBD_TR
cd07167	263-344	NR_DBD_Lrh-1_like
smart00399	262-331	ZnF_C4
cd06956	262-334	NR_DBD_RXR
cd07168	262-342	NR_DBD_DHR4_like
cd06960	263-336	NR_DBD_HNF4A
cd06967	262-334	NR_DBD_TR2_like
cd06964	263-341	NR_DBD_RAR
cd07170	262-342	NR_DBD_ERR
cd06958	263-334	NR_DBD_COUP_TF
cd06937	370-591	NR_LBD_RAR
cd06968	263-346	NR_DBD_ROR
cd07169	263-344	NR_DBD_GCNF_like
cd07166	262-348	NR_DBD_REV_ERB
cd07165	263-348	NR_DBD_DmE78_like
cd07164	263-334	NR_DBD_PNR_like_1
cd07171	262-343	NR_DBD_ER
cd07155	263-336	NR_DBD_ER_like
smart00430	420-565	HOLI
cd07154	263-334	NR_DBD_PNR_like
cd07179	263-334	2DBD_NR_DBD2
cd07158	263-334	NR_DBD_Ppar_like
cd06957	263-336	NR_DBD_PNR_like_2
cd07161	260-337	NR_DBD_EcR
cd06965	262-346	NR_DBD_Ppar
cd07163	263-334	NR_DBD_TLX
cd07068	414-596	NR_LBD_ER_like
cd07156	263-333	NR_DBD_VDR_like
cd06962	260-336	NR_DBD_FXR
cd06970	262-336	NR_DBD_PNR
cd07160	259-336	NR_DBD_LXR
cd06959	262-333	NR_DBD_EcR_like
cd06929	401-573	NR_LBD_F1
cd06955	262-348	NR_DBD_VDR
cd07162	262-342	NR_DBD_PXR
cd06938	395-585	NR_LBD_EcR
cd06935	367-594	NR_LBD_TR
pfam00104	388-578	Hormone_recep
cd06966	263-331	NR_DBD_CAR
cd06954	401-585	NR_LBD_LXR
cd06946	388-596	NR_LBD_ERR
cd06940	417-567	NR_LBD_REV_ERB
cd06941	404-565	NR_LBD_DmE78_like
cd06949	419-583	NR_LBD_ER
cd07172	262-329	NR_DBD_GR_PR
cd07173	263-328	NR_DBD_AR
cd06963	263-335	NR_DBD_GR_like
cd06948	420-598	NR_LBD_COUP-TF
cd06930	420-565	NR_LBD_F2
cd06943	420-577	NR_LBD_RXR_like
cd07157	263-330	2DBD_NR_DBD1
cd06950	420-577	NR_LBD_Tlx_PNR_like
cd06939	410-592	NR_LBD_ROR_like
cd06932	376-594	NR_LBD_PPAR
cd06931	420-578	NR_LBD_HNF4_like
cd06933	368-565	NR_LBD_VDR
cd06952	420-578	NR_LBD_TR2_like
cd06953	420-563	NR_LBD_DHR4_like
cd07069	420-583	NR_LBD_Lrh-1
cd06934	406-583	NR_LBD_PXR_like
cd06944	420-583	NR_LBD_Ftz-F1_like
cd06936	394-565	NR_LBD_Fxr
cd06942	402-563	NR_LBD_Sex_1_like
cd07073	391-565	NR_LBD_AR
cd07074	420-562	NR_LBD_PR

Ontology Information

HPRD ID	3574
Molecular Class	Not Available
Molecular Function	Receptor binding (GO:0005102)
Biological Process	Cell communication (GO:0007154); Signal transduction (GO:0007165)

SNP Information

View SNP Geneview Report

Drug Information

No matching records could be found.

External Links

ArrayExpress GO
ICGC GO
Cancer3D GO
COSMIC GO
NCG GO
TSGene GO
Tumor Gene Family of Databases GO
CCDB GO
G2SBC GO
Osteosarcoma Database GO
RCDB GO

ArrayExpress	GO
ICGC	GO
Cancer3D	GO
COSMIC	GO
NCG	GO
TSGene	GO
Tumor Gene Family of Databases	GO
CCDB	GO
G2SBC	GO
Osteosarcoma Database	GO
RCDB	GO