Search results:
General Information
| Gene_Symbol | Gene_ID | Gene_Name | Chromosome | Alias |
|---|---|---|---|---|
| PEBP1 | 5037 | phosphatidylethanolamine binding protein 1  | 12 | RKIP, HCNP, PEBP  |
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 23632477    | 2013 | Cell line : - Source : - Sample Type : CRC tumor and normal tissue No. of Sample : 220 Stage : - | Tissue microarray | Down-regulation | - | The clinical relevance of RKIP expression as an independent prognostic factor is restricted to the tumour centre. Loss of RKIP predicts features of EMT and correlates with frequent distant metastasis. Whole-tissue sections of 220 well-characterised CRCs were immunostained for RKIP. |
| 23460950    | 2013 | Cell line : - Source : - Sample Type : CRC tumor and normal tissue No. of Sample : 220 patients Stage : Duke stage B | Tissue microarray, pyrosequencing | Down-regulation | - | RKIP is potential in identifying 'high-risk' Dukes'B patients.It is this high-risk group which is most likely to benefit from close postoperative monitoring and may derive the most benefit from adjuvant therapy. |
Gene Details

| Gene Type | protein coding |
|---|---|
| Gene Family | |
| Description | -   |
| Chromosome | 12 |
| Location | 12q24 |
| Start | 118136065   |
| End | 118145585   |
| Strand | +   |
| Gene Sequence |    Download   Select all |
| Length | 9521   |
| OMIM ID | 604591    |
| HGNC ID | HGNC:8630    |
| Unigene ID | Hs.433863    |
| Ensembl ID | ENSG00000089220    |
| PharmGKB ID | -    |
mRNA Information
| mRNA ID | NM_002567.2 |
|---|---|
| Exon | join(1..280,1975..2084,3387..3487,8522..9521)   | mRNA Sequence |    Download   Select all |
| Length | 1507   |
CDS Information
| Location | join(146..280,1975..2084,3387..3487,8522..8739) |
|---|---|
| CDS Sequence |    Download   Select all |
| CCDS ID | CCDS9187.1 |    
Protein Information
| Protein ID | NP_002558.1 |
|---|---|
| Protein Name | phosphatidylethanolamine binding protein 1 |
| Molecular Wt. (Da) | 20926 |
| Protein Sequence |    Download   Select all |
| Length | 187   |
| Uniprot ID | Q99729 |    
| Ensembl Protein ID | ENSP00000348093   |    
Post-translational Modification Information (Source : HPRD)
| Residue | Type | site |
|---|---|---|
| S | Phosphorylation | 153 |
| S | Phosphorylation | 153 |
| S | Phosphorylation | 153 |
| S | Phosphorylation | 153 |
| S | Phosphorylation | 153 |
| S | Phosphorylation | 52;- |
| T | Phosphorylation | 42 |
| T | Phosphorylation | 51 |
| S | Phosphorylation | 54 |
| S | Phosphorylation | 99 |
| Y | Phosphorylation | 120 |
| Y | Phosphorylation | 125 |
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING)      View   
| Interactant Gene ID (Source: HPRD) | Gene Symbol | HPRD ID | Ref Seq ID | Technique | References |
|---|---|---|---|---|---|
| 5594 |    MAPK1 |    1496 |    NP_002736.3 |    in vitro;in vivo |    1   075   779   210   490   020    |
| 5604 |    MAP2K1 |    1469 |    NP_002746.1 |    in vitro;in vivo |    10757792    |
| 5894 |    RAF1 |    1265 |    NP_002871.1 |    in vitro |    17097642    |
| 6885 |    MAP3K7 |    4011 |    NP_663304.1 |    in vivo |    11585904    |
| 8614 |    STC2 |    4717 |    NP_003705.1 |    yeast 2-hybrid |    16169070    |
| 57685 |    CACHD1 |    13874 |    NP_065976.2 |    yeast 2-hybrid |    12421765    |
| 84246 |    MED10 |    14680 |    NP_115662.2 |    yeast 2-hybrid |    16169070    |
Pathway Information
No matching records could be found.
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| cd00866 | 23-171  | PEBP_euk |
| cl00227 | 23-171  | PEBP superfamily |
| pfam01161 | 22-170  | PBP |
| cd00457 | 34-171  | PEBP |
| PLN00169 | 25-165  | PLN00169 |
| COG1881 | 53-136  | PEBP |
| cd00865 | 53-125  | PEBP_bact_arch |
| TIGR00481 | 52-130  | TIGR00481 |
| PRK09818 | 38-143  | PRK09818 |
Ontology Information
| HPRD ID | 849 |    
|---|---|
| Molecular Class | Protease inhibitor |
| Molecular Function | Transcription factor activity (GO:0003700) |
| Biological Process | Regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism (GO:0019219)   |
Drug Information
No matching records could be found.
External Links
| ArrayExpress | GO |    
|---|---|
| ICGC | GO |    
| Cancer3D | GO |    
| COSMIC | GO |    
| NCG | GO |    
| TSGene | GO |    
| Tumor Gene Family of Databases | GO |    
| CCDB | GO |    
| G2SBC | GO |    
| Osteosarcoma Database | GO |    
| RCDB | GO |    
