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General Information
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 22968445 | 2012 | Cell line : - Source : Department of Pathology of Wrocaw Medical University. Sample Type : CRC tumor and normal tissue No. of Sample : 8 Stage : - | Laser capture microdissection,FFPE-FASP,SAX fractionation,LC-MSMS,Label-free quantitation. | Up-regulation | 3.4 | - |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | Importins |
| Description | Importins, including IPO11, are a members of the karyopherin/importin-beta family of transport receptors (see KPNB1; 602738) that mediate nucleocytoplasmic transport of protein and RNA cargoes (Plafker and Macara, 2000 [PubMed 11032817]).[supplied by OMIM, Sep 2008] |
| Chromosome | 5 |
| Location | 5q12.1 |
| Start | 62412746 |
| End | 62628589 |
| Strand | - |
| Gene Sequence | Download Select all |
| Length | 215844 |
| OMIM ID | 610889 |
| HGNC ID | HGNC:20628 |
| Unigene ID | Hs.482269 Hs.623985 |
| Ensembl ID | ENSG00000086200 |
| PharmGKB ID | - |
mRNA Information
| mRNA ID | NM_016338.4 |
|---|---|
| Exon | join(1..184,24529..24672,30238..30338,37182..37254, 38985..39188,54386..54518,57505..57563,61671..61719, 63938..64008,70356..70548,71265..71417,72674..72717, 75026..75116,76557..76604,77370..77475,81253..81379, 91922..91955,92113..92153,93496..93612,102643..102756, 113397..113512,117964..118040,123957..124036, 124464..124544,137622..137717,138478..138591, 148391..148512,178832..178927,189019..189103, 214409..215844) | mRNA Sequence | Download Select all |
| Length | 4420 |
CDS Information
| Location | join(6269..6382,24529..24672,30238..30338,37182..37254, 38985..39188,54386..54518,57505..57563,61671..61719, 63938..64008,70356..70548,71265..71417,72674..72717, 75026..75116,76557..76604,77370..77475,81253..81379, 91922..91955,92113..92153,93496..93612,102643..102756, 113397..113512,117964..118040,123957..124036, 124464..124544,137622..137717,138478..138591, |
|---|---|
| CDS Sequence | Download Select all |
| CCDS ID | CCDS47217.1 |
Protein Information
| Protein ID | NP_001128251.1 |
|---|---|
| Protein Name | Importin 11 |
| Molecular Wt. (Da) | 116877 |
| Protein Sequence | Download Select all |
| Length | 1015 |
| Uniprot ID | P16591 |
| Ensembl Protein ID | ENSP00000281092 |
Post-translational Modification Information (Source : HPRD)
No matching records could be found.
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
| Interactant Gene ID (Source: HPRD) | Gene Symbol | HPRD ID | Ref Seq ID | Technique | References |
|---|---|---|---|---|---|
| 5901 | RAN | 3109 | NP_006316.1 | in vivo | 11809816 |
| 6136 | RPL12 | 1603 | NP_000967.1 | in vivo | 11809816 |
| 10477 | UBE2E3 | 5000 | NP_006348.1 | in vitro;yeast 2-hybrid | 11809816 |
Pathway Information
No matching records could be found.
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| pfam03810 | 28-100 | IBN_N |
| cl04271 | 28-100 | IBN_N superfamily |
| smart00913 | 28-95 | IBN_N |
| COG5657 | 10-972 | CSE1 |
| COG5656 | 8-650 | SXM1 |
Ontology Information
| HPRD ID | 622 |
|---|---|
| Molecular Class | Transport/cargo protein |
| Molecular Function | Growth factor activity (GO:0008083) |
| Biological Process | Cell communication (GO:0007154); Signal transduction (GO:0007165) |
Drug Information
No matching records could be found.