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General Information
- Evidence
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Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 24691442 | 2014 | Cell line : - Source : - Sample Type : - No. of Sample : - Stage : - | Plasmids, transfection, and infection of human cell lines,Antibody generation, immunofluorescence, and immunohistochemistry,Immunoblotting,2D and 3D cell culture,Magnetically attachable stencil invasion assay,Mouse xenografts,RNA isolation, qRT-PCR, and qPCR array analysis.MultiOmyx, a multiplex immunofluorescence-based methodology. | Up-regulation | - | Coexpression of cytosolic PLAC8, CDH3, and VIM at the leading edge of a human colorectal tumor, supporting a role for PLAC8 in cancer invasion in vivo. |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | - |
| Description | - |
| Chromosome | 4 |
| Location | 4q21.22 |
| Start | 84011201 |
| End | 84035911 |
| Strand | - |
| Gene Sequence | Download Select all |
| Length | 24711 |
| OMIM ID | 607515 |
| HGNC ID | HGNC:19254 |
| Unigene ID | Hs.546392 |
| Ensembl ID | ENSG00000145287 |
| PharmGKB ID | PA134950814 |
Protein Information
| Protein ID | NP_001124187.1 |
|---|---|
| Protein Name | placenta-specific 8 |
| Molecular Wt. (Da) | 0 |
| Protein Sequence | Download Select all |
| Length | 115 |
| Uniprot ID | Q9P2N4 |
| Ensembl Protein ID | ENSP00000295903 |
Post-translational Modification Information (Source : HPRD)
No matching records could be found.
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
No matching records from HPRD source could be found.
Pathway Information
No matching records could be found.
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| TIGR01571 | 24-108 | A_thal_Cys_rich |
| cl04722 | 24-108 | PLAC8 superfamily |
| pfam04749 | 26-106 | PLAC8 |
Ontology Information
| HPRD ID | 6024 |
|---|---|
| Molecular Class | Cytokine |
| Molecular Function | Receptor signaling complex scaffold activity (GO:0030159) |
| Biological Process | Biological_process unknown (GO:0000004) |
Drug Information
No matching records could be found.