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General Information



Gene_Symbol Gene_ID Gene_Name Chromosome Alias
RAB6B 51560 RAB6B, member RAS oncogene family  3- 







  • Evidence
  • Gene
  • mRNA
  • CDS
  • Protein
  • PTM
  • Enzyme
  • PPi
  • Pathway
  • Structural
  • Domain
  • Ontology
  • SNP
  • Drug
  • External Links



Evidence Information


Pubmed ID Year Sample Information Techniques Mechanism Fold Change Remark
25412953   2015Cell line : -

Source : Gene Expression Omnibus (GEO) database

Sample Type : CRC tumor and normal tissues

No. of Sample : 8

Stage : -

Small RNA-seq and RNA-seqUp-regulation-miRNA-338-5p target gene RAB6B, FAP, and CTGF were identified as oncogenes.


Gene Details



NC_000003.11 (133543079..133614691, complement)

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Gene Type protein coding
Gene Family RAB, member RAS oncogene
Description -  
Chromosome 3
Location 3q22.1
Start 133543079  
End 133614691  
Strand -  
Gene Sequence

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Length 71613  
OMIM ID 615852   
HGNC ID HGNC:14902   
Unigene ID Hs.715344   
Ensembl ID ENSG00000154917   
PharmGKB ID PA34147   

mRNA Information


mRNA ID ?NM_016577.3
Exon  
mRNA Sequence

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Length  



CDS Information


   
Location
CDS Sequence

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CCDS ID CCDS3082.1



Protein Information


      
Protein IDNP_057661.3
Protein NameRAB6B, member RAS oncogene family
Molecular Wt. (Da)0
Protein Sequence

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Length 208  
Uniprot IDP55000
Ensembl Protein ID ENSP00000246515  



Post-translational Modification Information (Source : HPRD)


No matching records could be found.

Enzyme Information


No matching records could be found.

PPi Information


(Click to view network : Source STRING)      View   

                                                                           
Interactant Gene ID (Source: HPRD) Gene Symbol HPRD ID Ref Seq ID Technique References
4086SMAD13356NP_005891.1in vivo15761153   
7046TGFBR11822NP_004603.1in vivo15761153   
10112KIF20A9292NP_005724.1yeast 2-hybrid10893188   
23085ERC16181NP_829884.1in vitro;yeast 2-hybrid11929610   
23637RABGAP16575NP_036329.3yeast 2-hybrid10893188   


Pathway Information


No matching records could be found.

Structure Information


No matching records could be found.

Domain Information




ID Location Description
cd0186114-174  Rab6
cl2145514-174  P-loop_NTPase superfamily
cd0015414-172  Rab
smart0017514-171  RAB
cd0186013-175  Rab5_related
cd0412314-174  Rab21
cd0186714-174  Rab8_Rab10_Rab13_like
cd0186914-174  Rab1_Ypt1
cd0186314-171  Rab18
cd0186814-172  Rab11_like
cd0411314-174  Rab4
cd0186414-174  Rab19
cd0186614-174  Rab2
cd0087615-172  Ras
cd0411113-171  Rab39
cd0186514-170  Rab3
cd0186214-182  Rab7
cd0410714-208  Rab32_Rab38
cd0411214-174  Rab26
cd0411414-174  Rab30
cd0412214-171  Rab14
cd0411714-171  Rab15
cd0410914-182  Rab28
cd0410615-172  Rab23_like
cd0411014-167  Rab35
smart0001012-170  small_GTPase
cd0411815-206  Rab24
smart0017314-170  RAS
cd0411512-174  Rab33B_Rab33A
cd0412015-170  Rab12
cd0412715-165  Rab27A
cd0410815-172  Rab36_Rab34
cd0015715-167  Rho
cd0414415-197  Ras2
cd0413914-167  RalA_RalB
cd0412111-171  Rab40
smart0017416-167  RHO
cd0413715-186  RheB
cd0410115-173  RabL4
cd0417613-174  Rap2
cd0411614-167  Rab9
cd0411915-167  RJL
cd0088217-172  Ras_like_GTPase
cd0413212-168  Rho4_like
cd0414615-170  RERG_RasL11_like
cd0414512-167  M_R_Ras_like
cd0414814-188  RGK
cd0413614-167  Rap_like
cd0413015-167  Wrch_1
cd0417513-167  Rap1
cd0412415-168  RabL2
cd0412615-167  Rab20
cd0413813-167  H_N_K_Ras_like
cd0417714-167  RSR1
cd0414715-168  Ras_dva
cd0414112-168  Rit_Rin_Ric
cd0414014-168  ARHI_like
cd0991413-173  RocCOR
cd0087714-181  Ran
cd0412815-174  Spg1
cd0413415-172  Rho3
cd0412915-167  Rho2
cd0413113-168  Rnd
cd0187012-167  RhoA_like
pfam0847715-129  Miro
cd0187115-167  Rac1_like
cd0413315-167  Rop_like
cd0414314-172  Rhes_like
cd0187511-174  RhoG
cd0187415-167  Cdc42
cd0413514-167  Tc10
cd0417415-173  Rnd1_Rho6
cd0087815-167  Arf_Arl
cd0417213-167  Rnd3_RhoE_Rho8
cd0189315-167  Miro1
cd0417315-188  Rnd2_Rho7
pfam0002512-171  Arf
cd0414214-168  RRP22
cd0187314-167  RhoBTB
cd0415214-182  Arl4_Arl7
cd0415615-172  ARLTS1
cd0415919-163  Arl10_like
cd041539-132  Arl5_Arl8
cd0410315-171  Centaurin_gamma
COG22299-166  Srp102
cd0087915-130  Sar1
smart001777-160  ARF
cd041497-132  Arf6
cd0416062-165  Arfrp1
cd0416414-166  trmE
cd0088017-174  Era_like
cd0410517-130  SR_beta
cd0415815-140  ARD1
cd0187988-176  FeoB
cd0189219-173  Miro2
cd0187883-174  HflX
pfam02421114-170  FeoB_N
cd0415412-165  Arl2
cd0189514-173  EngA2
cd0410215-107  RabL3
cd0415511-132  Arl3
cd0185581-180  YqeH
COG0378117-174  HypB
cd01898121-174  Obg
pfam0007115-175  Ras
PTZ0009934-193  PTZ00099
PLN0310814-205  PLN03108
COG110012-206  Gem1
PLN0311014-170  PLN03110
PLN031182-206  PLN03118
PTZ0013214-181  PTZ00132
PTZ0036913-187  PTZ00369
PLN0307114-181  PLN03071
TIGR0023114-167  small_GTP
smart0017619-181  RAN
COG11609-167  Der
pfam0467015-157  Gtr1_RagA
COG04863-183  MnmE
PRK052913-166  trmE
COG226273-176  HflX
COG037012-176  FeoB
TIGR0359414-173  GTPase_EngA
PRK00089121-175  era


Ontology Information


   
HPRD ID12426
Molecular ClassGTPase
Molecular FunctionMetallopeptidase activity (GO:0008237)
Biological ProcessProtein metabolism (GO:0019538)  



SNP Information


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Drug Information


No matching records could be found.

External Links


                                 
ArrayExpressGO
ICGCGO
Cancer3DGO
COSMICGO
NCGGO
TSGeneGO
Tumor Gene Family of DatabasesGO
CCDBGO
G2SBCGO
Osteosarcoma DatabaseGO
RCDBGO