Search results:
General Information
| Gene_Symbol | Gene_ID | Gene_Name | Chromosome | Alias |
|---|---|---|---|---|
| ASB4 | 51666 | Ankyrin repeat and SOCS box-containing 4 | 7 | ASB-4 |
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 22930170 | 2012 | Cell line : KM 12C, KM 12SM , HT 29 Source : ATCC Sample Type : - No. of Sample : - Stage : - | Microarray analysis,Real time RT-PCR and Flow cytometry | Down-regulation | - | Gene differentially expressed and analysed bye by Microarray. |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | Ankyrin repeat domain containing |
| Description | The protein encoded by this gene is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. They contain ankyrin repeat sequence and SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. Multiple alternatively spliced transcript variants have been described for this gene but some of the full length sequences are not known. [provided by RefSeq, Jul 2008] |
| Chromosome | 7 |
| Location | 7q21-q22 |
| Start | 95461542 |
| End | 95540231 |
| Strand | + |
| Gene Sequence | Download Select all |
| Length | 78690 |
| OMIM ID | 605761 |
| HGNC ID | HGNC:16009 |
| Unigene ID | Hs.602765 |
| Ensembl ID | ENSG00000005981 |
| PharmGKB ID | - |
mRNA Information
| mRNA ID | XM_011516301.1 |
|---|---|
| Exon | join(1..58,9151..9264,34217..34516,66272..66762, 74896..75009,76030..78690) | mRNA Sequence | Download Select all |
| Length | 3738 |
CDS Information
| Location | join(9258..9264,34217..34516,66272..66762,74896..75009, 76030..76218) |
|---|---|
| CDS Sequence | Download Select all |
| CCDS ID | - |
Protein Information
| Protein ID | NP_057200.1 |
|---|---|
| Protein Name | Ankyrin repeat and SOCS box-containing 4 |
| Molecular Wt. (Da) | 48064 |
| Protein Sequence | Download Select all |
| Length | 426 |
| Uniprot ID | P05230 |
| Ensembl Protein ID | ENSP00000338548 |
Post-translational Modification Information (Source : HPRD)
No matching records could be found.
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
| Interactant Gene ID (Source: HPRD) | Gene Symbol | HPRD ID | Ref Seq ID | Technique | References |
|---|---|---|---|---|---|
| 55662 | HIF1AN | 9426 | NP_060372.2 | in vivo | 17636018 |
Pathway Information
No matching records could be found.
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| cd00204 | 77-191 | ANK |
| cl02529 | 77-191 | ANK superfamily |
| cd00204 | 172-294 | ANK |
| cl02529 | 172-294 | ANK superfamily |
| cd03723 | 379-426 | SOCS_ASB4_ASB18 |
| cl02533 | 379-426 | SOCS superfamily |
| cd00204 | 106-217 | ANK |
| cd00204 | 77-160 | ANK |
| pfam00023 | 106-134 | Ank |
| smart00248 | 106-135 | ANK |
| cd03716 | 379-404 | SOCS_ASB_like |
| cd03587 | 380-404 | SOCS |
| cd00204 | 246-316 | ANK |
| pfam07525 | 381-404 | SOCS_box |
| pfam13606 | 106-135 | Ank_3 |
| pfam12796 | 79-169 | Ank_2 |
| pfam12796 | 179-282 | Ank_2 |
| PHA03095 | 80-321 | PHA03095 |
| PHA03095 | 94-299 | PHA03095 |
| PHA02876 | 93-316 | PHA02876 |
| PHA03100 | 61-282 | PHA03100 |
| PHA03100 | 109-285 | PHA03100 |
| PHA02876 | 24-283 | PHA02876 |
| pfam12796 | 111-249 | Ank_2 |
| PHA02874 | 77-259 | PHA02874 |
| PHA02874 | 94-313 | PHA02874 |
| COG0666 | 106-259 | ANKYR |
| COG0666 | 72-284 | ANKYR |
| PHA02878 | 93-259 | PHA02878 |
| PHA02875 | 79-281 | PHA02875 |
| PHA02875 | 54-289 | PHA02875 |
| PHA02878 | 157-316 | PHA02878 |
| PHA02874 | 119-294 | PHA02874 |
| COG0666 | 77-182 | ANKYR |
| PHA02878 | 101-316 | PHA02878 |
| PHA02874 | 177-294 | PHA02874 |
| PHA02874 | 109-377 | PHA02874 |
| PHA03100 | 81-207 | PHA03100 |
| pfam13637 | 79-126 | Ank_4 |
| PHA03100 | 94-205 | PHA03100 |
| PLN03192 | 107-207 | PLN03192 |
| PHA02875 | 77-244 | PHA02875 |
| PHA02875 | 82-316 | PHA02875 |
| pfam12796 | 231-316 | Ank_2 |
| PHA02876 | 233-298 | PHA02876 |
| pfam13857 | 94-146 | Ank_5 |
| PTZ00322 | 93-144 | PTZ00322 |
| TIGR00870 | 107-201 | trp |
| pfam13857 | 74-114 | Ank_5 |
| PTZ00322 | 236-285 | PTZ00322 |
| pfam13637 | 109-147 | Ank_4 |
| pfam13857 | 162-215 | Ank_5 |
| pfam13637 | 210-272 | Ank_4 |
Ontology Information
| HPRD ID | 2727 |
|---|---|
| Molecular Class | Adapter molecule |
| Molecular Function | Growth factor activity (GO:0008083) |
| Biological Process | Cell communication (GO:0007154); Signal transduction (GO:0007165) |
Drug Information
No matching records could be found.