Search results:
General Information
| Gene_Symbol | Gene_ID | Gene_Name | Chromosome | Alias |
|---|---|---|---|---|
| PIWIL2 | 55124 | piwi-like RNA-mediated gene silencing 2 | 8 | HILI, FLJ10351, Mili, CT80 |
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 23110023 | 2012 | Cell line : - Source : Kosin University Gospel Hospital in Busan, Korea. Sample Type : CRC tumor and normal tissue No. of Sample : 60 Stage : - | Immunohistochemistry | Up-regulation | - | PIWIL2 expression was relatively higher in colorectal carcinomas and it was significantly correlated with variable clinicopathologic indicators for a poor prognosis. |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | Argonaute/PIWI family |
| Description | PIWIL2 belongs to the Argonaute family of proteins, which function in development and maintenance of germline stem cells (Sasaki et al., 2003 [PubMed 12906857]).[supplied by OMIM, Mar 2008] |
| Chromosome | 8 |
| Location | 8p24 |
| Start | 22132810 |
| End | 22215560 |
| Strand | + |
| Gene Sequence | Download Select all |
| Length | 82751 |
| OMIM ID | 610312 |
| HGNC ID | HGNC:17644 |
| Unigene ID | Hs.614809 |
| Ensembl ID | ENSG00000197181 |
| PharmGKB ID | PA38461 |
Protein Information
| Protein ID | NP_001129193.1 |
|---|---|
| Protein Name | piwi-like RNA-mediated gene silencing 2 |
| Molecular Wt. (Da) | 0 |
| Protein Sequence | Download Select all |
| Length | 973 |
| Uniprot ID | Q96A65 |
| Ensembl Protein ID | ENSP00000253861 |
Post-translational Modification Information (Source : HPRD)
No matching records could be found.
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
| Interactant Gene ID (Source: HPRD) | Gene Symbol | HPRD ID | Ref Seq ID | Technique | References |
|---|---|---|---|---|---|
| 23405 | DICER1 | 5875 | NP_803187.1 | in vitro;in vivo | 12906857 |
| 54514 | DDX4 | 5593 | NP_077726.1 | in vitro;in vivo | 14736746 |
Pathway Information
| Pathway Name | Pathway ID |
|---|---|
| Dorso-ventral axis formation | hsa04320 |
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| cd04658 | 512-956 | Piwi_piwi-like_Euk |
| cl00628 | 512-956 | Piwi-like superfamily |
| cd02845 | 387-504 | PAZ_piwi_like |
| cl00301 | 387-504 | PAZ superfamily |
| cd02826 | 559-956 | Piwi-like |
| smart00950 | 668-959 | Piwi |
| pfam02171 | 668-959 | Piwi |
| cd04657 | 551-952 | Piwi_ago-like |
| smart00949 | 388-526 | PAZ |
| cd02825 | 387-501 | PAZ |
| pfam02170 | 390-508 | PAZ |
| cd04659 | 677-957 | Piwi_piwi-like_ProArk |
| cd02844 | 393-513 | PAZ_CAF_like |
| cd02843 | 401-472 | PAZ_dicer_like |
| cd02846 | 424-480 | PAZ_argonaute_like |
| pfam08699 | 338-386 | DUF1785 |
| cl07356 | 338-386 | DUF1785 superfamily |
| PLN03202 | 362-948 | PLN03202 |
Ontology Information
| HPRD ID | 18177 |
|---|---|
| Molecular Class | Transcription regulatory protein |
| Molecular Function | Receptor binding (GO:0005102) |
| Biological Process | Biological_process unknown (GO:0000004) |
Drug Information
No matching records could be found.