Search results:
General Information
| Gene_Symbol | Gene_ID | Gene_Name | Chromosome | Alias |
|---|---|---|---|---|
| IMP3 | 55272 | IMP3, U3 small nucleolar ribonucleoprotein | 15 | FLJ10968, BRMS2 |
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 19672661 | 2009 | Cell line : - Source : - Sample Type : CRC tumor and normal tissue No. of Sample : 203 Stage : - | Tissue microarray,immunohistochemistry,RT-PCR and Western blotting | Up-regulation | - | IMP3 may play an important role in colon cancer progression and could serve as a prognostic biomarker to identify patients at risk of developing metastasis or recurrence after colonectomy. |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | - |
| Description | This gene encodes the human homolog of the yeast Imp3 protein. The protein localizes to the nucleoli and interacts with the U3 snoRNP complex. The protein contains an S4 domain. [provided by RefSeq, Jul 2008] |
| Chromosome | 15 |
| Location | 15q24 |
| Start | 75931426 |
| End | 75941047 |
| Strand | - |
| Gene Sequence | Download Select all |
| Length | 9622 |
| OMIM ID | 612980 |
| HGNC ID | HGNC:14497 |
| Unigene ID | Hs.513043 |
| Ensembl ID | ENSG00000177971 |
| PharmGKB ID | PA25517 |
Protein Information
| Protein ID | NP_060755.1 |
|---|---|
| Protein Name | IMP3, U3 small nucleolar ribonucleoprotein |
| Molecular Wt. (Da) | 0 |
| Protein Sequence | Download Select all |
| Length | 184 |
| Uniprot ID | Q9HAZ2 |
| Ensembl Protein ID | ENSP00000270722 |
Post-translational Modification Information (Source : HPRD)
No matching records could be found.
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
| Interactant Gene ID (Source: HPRD) | Gene Symbol | HPRD ID | Ref Seq ID | Technique | References |
|---|---|---|---|---|---|
| 10199 | MPHOSPH10 | 10404 | NP_005782.1 | in vitro | 12655004 |
Pathway Information
| Pathway Name | Pathway ID |
|---|---|
| Ribosome biogenesis in eukaryotes | hsa03008 |
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| cd00165 | 109-172 | S4 |
| cl09940 | 109-172 | S4 superfamily |
| pfam01479 | 109-155 | S4 |
| smart00363 | 109-165 | S4 |
| COG0522 | 1-168 | RpsD |
| TIGR01018 | 30-167 | uS4_arch |
| PTZ00155 | 30-164 | PTZ00155 |
| PRK04051 | 30-167 | rps4p |
| PLN00189 | 30-164 | PLN00189 |
Ontology Information
| HPRD ID | 6937 |
|---|---|
| Molecular Class | RNA binding protein |
| Molecular Function | Protein binding (GO:0005515) |
| Biological Process | Cell communication (GO:0007154); Signal transduction (GO:0007165) |
Drug Information
No matching records could be found.