CoReCG

Search results:

General Information

Gene_Symbol	Gene_ID	Gene_Name	Chromosome	Alias
AXL	558	AXL receptor tyrosine kinase	19	UFO, JTK11

Evidence
Gene
mRNA
CDS
Protein
PTM
Enzyme
PPi
Pathway
Structural
Domain
Ontology
SNP
Drug
External Links

Evidence Information

Pubmed ID	Year	Sample Information	Techniques	Mechanism	Fold Change	Remark
24170546	2014	Cell line : - Source : National University Hospital of Singapore Sample Type : CRC tumor and Normal tissue No. of Sample : 509 Stage : -	Western blotting, Immunofluorescence, Real-time reverse transcription-PCR, ELISA, tissue microarray	Up-regulation	-	AXL as a poor prognostic marker and important mediator of cell migration/invasiveness in colorectal cancer. high AXL mRNA and protein expression were found to be associated with poor overall survival in early-stage colorectal cancer tissues

Gene Details

Chromosome 19 - NC_000019.10 (41219199..41261767)
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Gene Type	protein coding
Gene Family	Immunoglobulin superfamily / V-set domain containing, "Immunoglobulin superfamily / Immunoglobulin-like domain containing", "Fibronectin type III domain containing"
Description	The protein encoded by this gene is a member of the Tyro3-Axl-Mer (TAM) receptor tyrosine kinase subfamily. The encoded protein possesses an extracellular domain which is composed of two immunoglobulin-like motifs at the N-terminal, followed by two fibronectin type-III motifs. It transduces signals from the extracellular matrix into the cytoplasm by binding to the vitamin K-dependent protein growth arrest-specific 6 (Gas6). This gene may be involved in several cellular functions including growth, migration, aggregation and anti-inflammation in multiple cell types. Alternative splicing results in multiple transcript variants of this gene.
Chromosome	19
Location	19q13.1
Start	41219199
End	41261767
Strand	+
Gene Sequence	>gi\|568815579:41219199-41261767 Homo sapiens chromosome 19, GRCh38.p2 Primary Assembly GTGAGGGAAGGAGGCAGGGGTGCTGAGAAGGCGGCTGCTGGGCAGAGCCGGTGGCAAGGGCCTCCCCTGC CGCTGTGCCAGGCAGGCAGTGCCAAATCCGGGGAGCCTGGAGCTGGGGGGAGGGCCGGGGACAGCCCGGC CCTGCCCCCTCCCCCGCTGGGAGCCCAACAACTTCTGAGGAAAGTTTGGCACCCATGGCGTGGCGGTGCC CCAGGATGGGCAGGGTCCCGCTGGCCTGGTGCTTGGCGCTGTGCGGCTGGGCGTGCATGGCCCCCAGGGG TGAGTGATGGGGGCTCCTTGGGGCAGGGATCCCCTCGGAGGGGCTGGGGCAGGGGTAGGAGGTGGGGGAT GATGGCAGGTGTGGGGGGCCTGGGCTGGCTTAGGGAGTTTCCTTGGGACCACAGAAAAGGGACTTCAAGG GAGGGAGACACAGACTCAGAGACACCAAGTGCGGCAGAGGGAGAGAAAGACTGAGAGAGGAACTGAAGGG CAGGGGGGACAGAAGAGAGGACCCGGAGAGACAGACAGACAAGGAGAAGCTGAGGGCAGGGGTGGGGGCT GGACCTGAGAAGGGGGCCATGGGGAGAGGGGCTGAGCTGAGGGTCGCCAGGAAGGAAGAAATCTTTCCGA AGGGGCACCGAGTCAGGCAGTGGGATGAGGAGGGCTCTGGAGCCCTGGGGGAAAACGCTTCTCCCTGCCA ACACCACCCCCCTGACCCGCCACTTGTCCCTACCCCACCAGTCCACTCCATCTCTGGGGAGGAGGCTCTC ACTTTGTCTCTCTGTCTCTGCCTCCAGCTCTGCTATCTCTGTGGGTCTCTGTTTCTCTCTCTTTCACAGT CTCTGCCTTTATCTCTCCCTGCTCTCTGAGTCTCTCTCTCTCTTCTCAGCCTCCCTCTGTGACTGTATCC CCCCTCCGCCCCCACCTTTTCTTCTCTCTTGAGGGCTGTTTCTTCATTTTTTCTGTCTTGCCTTGTATCT GTGCTCCTCTCTGTCTCATCTCCCCTGCCTTTCTCTGGCTTCTCCCTCCGCCACCACCCTTATCTCCCCC CACCACCACCCTTATCTCTCTCCCCCAACCCCTGATTCTTCCCCTCCATCCACCAGCACCAGCGCGACCT GTTAAGTCTCTAGAGACCTAAGAGAGGACGGAGGGGGCAGGGGCTGGCCCTGCCAGGCAGTGCAGGGCGT GGGAGGCTGCCAGATCCCGAGCCTCCTTCCCGACGGGATGGACGCTAGATCCCAGTCCCTTGGGAGGGCT CCCGTCCTCCTCTCAGAGCCTCCGCCCTCCACCCCACTCTGAGGTCACTCTGCAACTATGTCGGCCTAAG GGCCTGGCGGGGTCCTGGCCGCCGGTGGGCAGGCAAGGACAGGGTGGAACTGAGGGCCGGAAGGAGCTGG GGGGTTCCTAAGCTAACTCTTCCCATCTCCCCTCCAGGCACGCAGGCTGAAGAAAGTCCCTTCGTGGGCA ACCCAGGGAATATCACAGGTGCCCGGGGACTCACGGGCACCCTTCGGTGTCAGCTCCAGGTTCAGGGAGA GCCCCCCGAGGTACATTGGCTTCGGGATGGACAGATCCTGGAGCTCGCGGACAGCACCCAGACCCAGGTG CCCCTGGGTGAGGATGAACAGGATGACTGGATAGTGGTCAGCCAGCTCAGGTGTGTGGCCACATCCCCGA ATCCCACTCCCACCTCCGTCACACAGAGGGCAGAAAGCCCACCTGGGTGGGAACCCCAGTTTGACCACTT GTCAGCCGTGCGGCTTTGAGCATGTGATGGAACCTCTAGGTTTCGTTTTCCTCTTCTGCAAAATGAGTTA ATAATAGGACATACTTCGTGGTTGTCATGAGCTTCCAGACTGGACACCCTCTTTCCGTTCTGACAGACCC CCTCCCAGTGTCCAGCTCTGACCCTGAACCTCTCTGTCTCTCCTCTTGCCCTGTCAGAATCACCTCCCTG CAGCTTTCCGACACGGGACAGTACCAGTGTTTGGTGTTTCTGGGACATCAGACCTTCGTGTCCCAGCCTG GCTATGTTGGGCTGGAGGGTGAGCTCTGGGGTCAGGGGTCCTGAGGGGTCAGAGGACATGTGGCGCTCAT AGGTTGTGGGAAGTCAGGAATCCTGAGGGGTCAAGGTCAAAGGGTGCTGGAGGATTCAGGATGAACCTAG CGTCATACAGCCTAAGAATGTCAGAGTTTTGGGTGGTCAAGAAGCTGGGAGTCCATATAAGTTATGGTGC CAAGGCTGGGGGATTATATGTTCTGGGTGAAAAGACTTCTTGGGGGTAGTTGGATGTCCTAGGCATCAGA CACCATCAGGTCACAGGAGGCCATTCTGGTCTTCAGATAAGGCGTCAGAGGCACGCAACGTACCCCTGTC CCCACGACCCCAGCGGTCTCTTTTTTCTCATCCATAGAATGAGATGAGGATGAGCTGTCAGACATTCTGG AAGAGAGACATGAGGAGCTCAGCTATCGTGGGGGGTCTGACATGGGAGGAATCAGATATTGGGGTCACGT GTGTGTTGGGTATGGCTCAGGTGCCCTCGGGGATCAGATAAGGCAAGTCAATGACCCTGCAGGGTGGGTT TGCTGCCCAAAGCCTACAGCATCCTAGTGGTGAGTCAGGCATCTTGGGGCCTCAGAGGGACCCCAGCCTC TACCACTGCCCACCCCGCTAGGCTTGCCTTACTTCCTGGAGGAGCCCGAAGACAGGACTGTGGCCGCCAA CACCCCCTTCAACCTGAGCTGCCAAGCTCAGGGACCCCCAGAGCCCGTGGACCTACTCTGGCTCCAGGAT GCTGTCCCCCTGGCCACGGCTCCAGGTCACGGCCCCCAGCGCAGCCTGCATGTTCCAGGTGAGTCCGGGG ATGTGGGTCAGCTCCGAATAGGGGGCCGGGCAGGGCTGAAGTCAGGAGCAAGGGAACATTGCTACCTCTG CGTGAGTGTCTGACTGTCCTTCTGTCCCTCACTGTCTGTCTCTCTCGTTTCTCCCTCTGAGTCTGTCTCT GCCTCTCTGTCTCTACCTATCTTATTTCTCTCCGTATGCCTTTTTCTGTCTCTTTCTGTCTCTTGGTGTG TGTGTCTTTCTGTCTCTCTTTGTATGTGTCTCTCTCTCTGTCTCTCTGCTTCTCTCTCCCTCCATTCACC CCGGCCTCTCTCTGAATAGAATTCTTTGTCCTGGGTTTCCTCTGAGCTGTTCCATGGCTCGAGTGCGTGT GGGCCTGGTGCCCCTTTGTCAGCCCTTGACCCAAGCAGGGCACCGGAATCAACCGTGCCCTCCTCTCCTC CGCCTCCCTCCACAACCGGCCCACCTCCTGCCCTAACAAGCCTGCTGGCCTCAGTCAAAGGGAGGATGTC CAGCCCGGTCCCCACTGGGGAGATGGAACCCAAAGAAGAGAGAGCAGGAAGAAAGTAGGAGACAGAGGCT GGGCGTGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCTGAGGCGGGCGGATCACGAGGTCAGGA GATCAAGACCATCCTGGCTAACACGGTGAAACCCCATCTCTACTAAAAATACAAAAAATTAGCCGGGCGT GGTGGCGGGCGCCTGTAGTCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATGGCAGGAACCCGAGAGGCG GAGCTTGCAGTGAGCCGAGATTGCGCCACTGCACTCCAGCCTGGGCGACAGGGCGAGACTCCATCTCAAA AGAAAAAAAAAAAAAAAGAAAGTGGGAGACAGAGAGAGATAGAATGACATACACTGGAAGGGACAGGCCA CAGTGACCCAAGATGAACATAGACAGGACAGAGAGGCCGGGCATGGTGGCTCACGCCTGTAATCCCAGCA CTTTGGGAGGCTGAGGCAGGTGGATCACTTGAGGCTGGGAGTTCGAGACCAGCCTGGCCAACATGACAAA ACTCCATCTTTACCAAAAATACAAAAATTAGCCAGGCGTGGTGACGGGCATCTGTAGTCCCAGCTACTTG GGAGGCTGAGGCAGGAGAATCGCTTGAACCCGGGAGATGGAGGTTGCAGTGAGCCGAGATCACACCACTG CACTCCAGCCTGGGTGACAGAGCAAGACTCTGTCTCAAAACGAAAAACAAAACAAAATGAAAGACAGGAC AGGGAAGTTGGAGTGACAGAAACCCTCTCCTTCTTGGGGACCATTCCCTTCTGCACCATGCAGACGAGGA AGGACCGAGCTCAGGGTTATGCAGTGGTCAGGGGCATCACTGGGGGACCCTGGATTCAGGGGGTTCTCCC TACTGAAGGAGGAAAGACAGAGGAGCAGATGGCAGAGGCTCTGTAAAGGAAGGAGGCTGCAGCCTGGAGG GCATCAGCTTCCCGCACTCCCAACCTGCTGCCTCTCTCTGCTGGAATGAGGAGGGGCCTTCTGACTGGGG GTCTCCAGGGTGGAGGGAGGAGCTCACATTCTCAGCATTCCTGGGACCCTGAGTTGCAAGGAAGACCTGG TGAGCATGCTGACCCCAGAGGAGTGACTCAGGCCCATGGCTCGAGTGGCTGAGTAGGGACCAGGGTTGGG GATCGGGCATGAGTCAGCCTGGCAGGTCCCATGAGAAGGGGAGGGGAGGGAGAGAAATGGGGGCTGCACA GGTGTGAGGATCTGTGCATGTCTGTGTGGTGGTGGTGGGGTGTCTGGATATCTGTGTGTTCTGGATCTGA GTGTTAGTGTATCCGTCAGCACAACCTCTGTGTGAGGGTGTGCCTTGGCGAGGGTGGACTTCTGTGGATG TCCCATGTGTGGTGTGTGTGTGTGTGTGTGTGACTAAATATATTTCCTTCAGCTTGGATTCTGTCCCAAT ATGTGTTTGGATCTTTATAGCATGTCTCTCTCTCTACGTTTCTTAGGGGTTGCCCGTGTGTGGGTGTCTG TGTGTGTGCGCATGATGGAGTGTACCAGTGTCAGCCTGTGTCTGTCCCTCTTTTTTGTGTTTGTGTGTTC ACAGCTGGGACTCACTGTATGAAAGTAAAGTGTGCCTGGAGGGTAGTGGGTTTGGGGCTATGGTGCACAC CTCTCTGTATGGAGGTGGTAGTGTCAGCCCACAGGTGTGCAGCTATGGGTGTGAGAGTGTCCTAGTGAGA GCTTGTGTTCCCTTGCAGAATCAGAACGTGTCCATGGATAACTTGTGTTTCTTACCACCTTTTTTCCCCC TTATTTTTTTTCAAGATAAGCTCCCGCTGTGTAACCCAGGCTGGAGTGCAGTACTGTGATCATGGCTCAC TGTAGCCTCCACCTCCTGGGCTCAAGCAATCCTCCTACCTCAGCACCCTCCCACCCCTCAAGCAGCTGGG ACTATAGGCATGTGCCACCATACCCAGATAGTTTTTGAATTTTTTGGTAGAGACAGAGTCTCGCCATGTT GCCCAGGCTGCTCTTGAACTCCTGGCCTCAAGTGATCCTCCCGCCTCGGCCTCCCAAAGTGTTGGGATTT ACAGGCGTGAGCCACTGCTCTCAACCCTCAGCCTCTTACCAGCTTTCTGTGTGTGTCCATAGATGTCTCT GTGGCGTGTGTGTATATGTCACAGGGTAAGCATGTTGGTGTATGACTGTAGTCACAGACCTGTGTGTGTG TGTGTGTGTGTAACAGCACCCTCTGCTTCTCTCTGGTCTCCCTGTGTGTGCACTGGCCCCTGCTGCCTCT GAGTACATGACCTAAGGATGCTTACCAGTCAGCGTATAGATGTGTCTCTGTGTCAATCTATGTGTCCATG GCAGTGTCTCCATCCTTGTGTGTCTGCATCAGGCCTGCGCATCTACGAAACTGTGTTTTTTTGTTTTTTG GGGTTTTTGTTTTGAGACGGAGTCTCACTCTGTCACCCAAGCTGGAGTGCAGTGGCACGATCTTGGCTTA CTGTAACTTCCGCCTCCGGGGTTCAAGGGATTCTCCTGCCTCAGCCTCCTGAGGAGCTGCGATTACAGGC ACGCCTGGCTTATTTTTGTATTTTTAGTAAAGACAGGGTTTCATGACAGGTTTGTCATGTTGGCCAGGCT GGTCTCAAACTCCTGACCTCAAGTGATCCACCGGCCTCGGCCTCCCAAAGTACTGGGATTACAGGCGTGA GCCACCGCACCCAGCGCAAATGTGTTTTTGTATCAGTCTGTGTCTGGGTGAACATGAAACCTGGGCGCAT CCAGCTCCATCTTATGGCGTAGATGGAGGCTTGGCTGTGAGGTGTACGCGTCGGTGTGTCTGTGTCTGAG CAGGTCAAAATGACCCTTCATTGTGTCCTGGTGTGTATCTATCTGTCCACCTCAACTCCATGTACGCTGT TACGTGGTGTGTGTCTCTGAATATACAGGGACATTTAAGTTTCTGTGTGTGTTGGCATCAGCCTAGATGT ACATTGCGTCGCTAGGTGTTTGTAATCAATGTGTACATGTGTGACTGTGTGTTTATGTGTTTGTCCCACG TTGGCTTGTATGCATACATGTCTCTTTATGAATGTACATCAGTGTCAGCCCGCGTGTATATGTGTGAGTC ACGGTGTTTTTGTGTCACTGTGTTTGTGACATCAGCCCTTGCATATCTGTGTGCCGTTAACTTACCAAGC GCTGCGTCTTCTGTGCTAATAACAGCCCCTGTGTGTTTAAGTGTGATTCATTGTGAGTGTGTGTGTGGGG GGGTTTGCTGTGTGAAGGAATTTCGTCCGTTTGTGTGCGTCTGTCCCTCTATCTGACTCAGGGCGTGCCC CTCCTCCTTCCATCCCTCTCATTCTCTGGAAAAGCTGGGGCGGAGAGCAGGGGTTGTGGGGGGATGGTCA GGACATCTGGAAAGCACATCTGGAATCGGCCTGCTCCTGTCGTCTTGCGGTAAAGCAAGAACCTTCTGGA GGGGAAGGGGTCCCAGTTCCTCCTGTCCCCTTCACTCAAGGTGCGGCCGTTGGGGCCTGGGAAGGGGGAT CCCGGCTCTGGCTCCGCGCCCCCGAAGCCGGCCGGAAGCGCTGGGGTGGGGAGGTGCCCCCGGTGACTCA CGCGGGGGCAGGAATGCTGCGGTCGGAACGGGACCCGGCTCCAGAACCCACCTCCAGCCCCAGGGCTTCT CCGGCCGGCGGCGCCAGCTCCCGCGCGCTGACCCTGGCGGGGCCCCACGTGCCAGGTGGCTGGACCCGAC CCAGGCTCCCCGCCCCCACTCGGGCCGCCCGCCCGGGACTGTACTGTTTCTCCTCCGGGCGGCGCGGGGG CTGCGGGCGCGGGGCCTTCAGGGCGCGGAGGCTGCGGGAGCGGGCACCTGACCTTGTCTGGGAACGGCCA CCTAGGAAGCCGCGACTGAGGAGCTCCCCTACCCTCCCCTTTCCGGCCTCTGCAGACTTTGCACCATTCC ACTCCCTCCGCTGACGGAGAAAAGGAAACTTTGTGTCTGCGGATGGAGAGCCTCCCTTGCCAACGCGGTG GGAACAGAGGCGTACACGCACGGAGCAAACACGAGAGACACGTACACAGATACTCAACACATGCACGTAC ACACCATCCACAGATACACGCAGGGTCACAAACATACCAGCTCAGAAACACAAACACAGATGCACAAGCA CACGCGTAAACAACACGCAGAACTGCAGTCGCACTTACAAGACTTGGTCCCAGGGCCGGGCACCGAGTGG CTCTGCCTGCGATCCAGCACTTTGGGAGGCCGAGGCGGGAGGATCGCTTGGGGCCAGAAGTTTGAGAGCA GCCTGGGCAACGTGGTGAGACTCTCCTCTTCTCTACAAAAAAAAATTGAAAAGTTAGCCAAGTGTGGTGG CCGCCTGTAGTCCCAGCTGCTTGGGAGGATGAGACAGGAGGATCGCTTGAGCCCTGGAGGTCAAGGCAGC AGTGAGCCGTGATTGTGCCACTGTACTGCAGCCTGGGAGATAGAGCAAGAACCTGTCTCAAAAAACAAAA CGAAAAACTTGGTCCTTCTTACATCCTAGCGCAGACATTGTGTGTGTGTGCTGGGGGAGGGGGGTGTCTA TGTTTCTACGTGTATCTGTGTTGGGGGATTCCCCTTATTCACCAGGATACGTTCTCTAAGAGCCCCCACA AAAGCCTGAAACAATGAATAATACTAAACCCTGTATATACTACACATAACTTTCTTTTTCCTTCACAATT TCGCAGATAGATTGTTTTCTTACTATAGATCTTAGCAACCTCAGTACATATATATATGATTATCTTTTTC TAAGTGGAGAATTTTCACCTTTTCACTTAAAAGGAAGCACTTTAAGGCTTCTCTTTGGCCTATCCGAATT GCAGCCATCACTATTTTGCACCCTGGGGCCTTTTTTTTTTTTTTTTAGACAGAGTCTCTCTCTGTCGCCC AGGCTGGAGTGCAGTGTGGCGACCTTGGCTCACTGCAACCTCCGCAGCCCGGGTTCTAGCAGTTATCGTG CCTCAGCCTCCCGAGTAGCTGGGATTACAGGCACGCGCCACCATGCCCGGCTGATTTTTTTGTATTTTTA GTAGAGACGGGGGTTTCACTGTGTTGCCCAGGCTTGTCTTAAACTCCTAATCTCAAGTGATCCACCCGCC TCGGCCTCCCAAAGTGCTGGGATTACAGATGTGAGCCATAGCACCCGGCCAGGCGATTATTTAGATAAAT AAGAGTTTCTTGAACTCTGCACTTGAGCACTGCAGTACCAGGACAGTTGATCTGATAGCTAAGTGACTTA CAGACAGGTATCAGATACAGCACTGAGATGCTGGACAAAGGGGGGATTCACGTTCTAGGCCAACCAGAGT GGGATGGCATGAGGTTTCATCACAGTACTCAGAACGGCATGCAATTTAAAACTTAGGAGTTATATCTGGA ATTTTCCATTGAAATATTTTTAGACCAAGTGTAACTGAAACCTCAAAAAGTGAAACCTCGGATAAAGGGG GACTGATGTACGTTGTATAGCGGTTTGTGTTGGGTATCTCTGTGTGCTTGCAGGTCTGTGTCTCTCGTGT TTGTCTCTGTAATTGTACGTGCTTCTGTGTGTGCACGCTGGTCATACCAACACCAACACCACCACGTTAG GGAGGGAAGGCAATCCACCTTCACTCGAAAACAGTTACTCAAGGCCGGGCACGGTGGCTCACACCTGTGA TCCCAGCACTTTGGGAGGCTGAGATGGGCAGATCACTTGAGGTCAGGAGTTCGAGACCAGCCTGGCCAAC ATGGTGAAACCCTATCTCTACTAAAAATTACAAAAATTAGCCGGGCATGGTGGCGCGCTCCTGTAATCCC AGCTACTCAGAAGGCTGAGGCAGGAGAATGGCTTGAACCCAGGAGGCAGAGGTTGCAGTGAGCCAAGATC ATGCCACTGCACTTTAGCCTGGGCAACAGAGCAAGACTCTCAAAAAACAAAAGAAAAAAACAGTCAAGAC ACAATACGTGAACTCCCCTATGGAATTACACATGCTCATATTTCTACACCTATGCCCAGGAATGCTCATA AGTACATAGCTGAACACAATTTCACTCACTCATTCAACAAGCATTTATGGCACACCTATTGTGTGCCAGG CCATCCTGACACAGCAGGGGACGAAACAGACACAACCCCTGCCCTCCTAGAGCTGACATTCTAGTGGGAG AAACTGACAATGGGCAAGGTACTTGGGTAACAGGTAAAGTATGTTGGGTGATGAGAAGAACCAAAGAGGA AAAGTAAAGCGGGAAGGGGATAGATTTGGAGAGGAAGCTCCAATTAGCTCCAATTTTATTGTATTTTTTC TTTCTTTCTTTGTCTTTTCTTTTCTTTCTTTTTTTTTTGAGACAGAGTTTCACTCTTGTTGCCCAGGCTG GAGTGCAATGGCGTGATCTCAGCTCACTGCAGCCTCTGCCTCCCGGGTTCAAGCTATTCTCCTGCCTCAG CCTCCTGAGTAGCTGGGATTAAAGGGGCCTGCCACTATGCCCAGCTAATTTTTTGTATTTTTAGTAGAGA CGAGGTTTCACTATGTTGGCCAGGCTGGTCTCGAACTTCGGACCTCAGGTGATCCACCCACCTCGGCCTC CTAAGGCTGGGATTACGGGCATGAACCACCGTGCCCAGCCTTTATTTTTCATTTTATTATTTTTAGTTTT TTTGAGACAGGGTCTCACTCTGTCACCCAGGTTGGAGTGCAGTGGTGTGATCACAGCTCACTGCAGCCTC CACCTCCCCGGGCACAGGTAGTCCTCCCACCTCAGCCTCCCAAGTAGCTGGGACTACAGGTGTGCACCAC CACACCCAGCTAATTTTTCTCTTTTTTGTAGAGATGGGGTCTCACCACGTTGCCCAGGCTGGTCTCTAAC TCCTGGCCTCAAGCGATCCTCCTGACTCAGCCTCCCAAAGTGCTGGGATTACAGTCATGAGTCACTATGC CTGGCCAAGCTCCAATATTAACAGGGTGGCCAGGCCTAGCGGACTGAGAGGTGTTGTTGAGGAACAAAAA TGAAAGAAGAGGGTGCGAGTCATGTAGACATTTGTGGAAGACTGTTTTGAGCACAGGGAACAGTGCACAG TTCTTGGAGTGGAAACATGCTTCATGTATGTGTTCCAGAGACACTGGAGGCCAGTGTGGCCGGAGAAGAG CGTGTGACAGGGAGAGTGGGAGAGGGGTTGGTAGGAGGCGAGCTTAGAGATGAACAGACATGTCTCCATT GATGTACAGCCATGGGCCAGTTTCCCTAAGTGTGTCTAGCAGGTGTGTGTGCTCATACTTGTGTCCTTGT GAGTTAGTGAGGGTGCCTGTGTTTGTGCATGTGAGTGTGTGCATGTTTGTGTGTCTCCTTGTGTGTGTGT GTCTGTGTATGCTTTTGTGTGTCTATGTGTGAGTATGTATATATGTGTCTATGTCCATATATATGAGCAC GTGTATTTCTGTGTGTGTCTATATATGTGTATATGAGTATGTGAGTATCTAGGTGTACGAATCTGTGTGT GTGAGACACAGTGTGTGTGTGTGGCTGTGTCTGTTTCTGTGTCTGTGTCTGTGTCTGTGTGTGAGCATAT GTGTTTATATGTGTGTGTATGAGTATGTGTCTCTGGGGTGTAAGAATGTGTGTGTGTGCCTGTGTGTGAC TGTGTGTGAGTCTGTGTGAGCATGTGTGTGTATGAGTATGTATCTCTCTCTGGGGTGTAAGAATGTGTGT GTGTGTGTGTATGCGCCTGTGCCTGTGTGTGTGTCTGAGCATATGTGTCTATGTGTGTGTATGAGTGTGT GTCTCTATCTGGGGTGTAAGAGTGAGTGTGCCTGTGACTGTGTGTGGTTGTGTGTCTTCATGTGTGTTTG TGTATGTGTGTTTTTGTGTGTGTATGCCTGTGCCTGTGTGTGGCTGTGTGTCTTTGTGTGTGTCTGTGTC TGTGTGTCTGTGTGTATGAGTGTGTGTGCCTGTGCCTGTGTGTGGCTGTGTGTGTCTTTGTGTGTTTCTG TGTGAGTATGTGTGTCTATGTGTGTGTATGAGTGTGTCTGTCTCTGGGGTGTAAGAATGTGTGTGTGAGA CAGTGTGTGTGCCTGTGCCTGTGCCTGTGTGTGTCTGTGTGTGTCTGTACTATGTGTGTCTGTGTGGCGG GAGGTTAGGGCTGAAACCAAGCCATCCTTGTGTTTGGGGATGGAGGCTGTGTTCCTAACTCATTGCCCTC AACTCTGCTAACCCTCCCTTCAGGCAAGTGCCTGTGTGGGCTGCACTGCCCCTGGTCAGGCAGGCCATGG TAGGAGTGGCCCGGCATGGCCCCGGAGCCCTTCCTGCCCCTCTCTGATATTGGACCCTTCCCTCATATGA CTCCCTAGGGCTGAACAAGACATCCTCTTTCTCCTGCGAAGCCCATAACGCCAAGGGGGTCACCACATCC CGCACAGCCACCATCACAGGTGACAGAGTTGGGAGGTGGGGAGCTGGGCGTCAGAGGGTGGGGTTTGGGT CCGGGGTCAGAGTGGGGGCAGAGAGCAGGGTAGGGAGCTTTGAGCAAAGGCTCCCCAGGGTCAATCTCTC CCGTTTGTCCACAGTGCTCCCCCAGCAGCCCCGTAACCTCCACCTGGTCTCCCGCCAACCCACGGAGCTG GAGGTGGCTTGGACTCCAGGCCTGAGCGGCATCTACCCCCTGACCCACTGCACCCTGCAGGTGAGACTCC CAAACTTGGTTCATTTCAGTCTCAGGCCTCCTTCCACCCACATCCACAACCCCCATCCTCTCCCTGGGAA CCCACCACTTCTCGGCCACTGTTGAGAAGCAGTAGAGCCTGGGGGGTTAAGCCAGATGTCCTGGGTTCGA ATCCTAGCTCCACCACCTTCTGGCTGTGTGACCTTGGGTAGGTGGCTTAATCTGTCCGGGGCTCAGCTCT CTTGTCTACAAAATGGACATAATGGTAGTGCCTACCTGGTATGCTTAGTGTGAAAATTCAATGAGTGAAT GCAAATTACCAACTTAAAATGGTATATAGAACATAGGAAACAAATTTAACAAAATTGGCCAGGCGCGGTG GCTCACACCTGTAATCCCAGCACTTTGGGAGGCCGAGGTGGGCGGATCACTTGAGGTCAGGAGTTCGAGA CCAGCCTGGCCAACATAGTGAAACCACATTTCTACTAAAAATACAAAAATTAACTGGGCCTGGTGGGACG CACTTGTAGTCCCAGCTACTGGGGAGGCTGAGGCAGGAGAATTGCTTGAACCTGGGAGGCGGAGGTTGCA GTGAGCCAAGATCGTGCCACTGCTCTCCAGCCTGGGTGACAGAGCGAGACTCTGTCTCAAAAAAAAAAAA GAAACAACAACAAAAAAAATTTAACAAAATGAAAATGATCAGCTGTTTTAATTATTTTCAGTATTAGTGA TGTTAACTCTAGCCAGAGTGGGAGCCCTGAGACAGCAGAGTCTGGAGCCATTTCTGTCACCACTGGATAC CCAGAACCCTCCACTTCTCCCATCCCAGCCCTGGCCACTCTGTGTGGTCACTGTCTGGGGATGGGTCTGT CCCCTACTGGAATGTGAGCTCTGACAGGGCAGGGCTGGAGCTGTCCCAGTCACCACTGGCTCCTCATTCT TGCCCAGCACAGGACCAGACATAGAGTAGGGAATATTCGCTAGAAGGATATATTACAACCCAGATGAGCT AGACCCAGCCTCTGCCCTCAAGTTGCTCCTAGAATAAGAAAACCAAAACCAGGCCAGGTGTGGTGGCTTA CACCTGTAACCCCAGCACTTTGGGAGGCCAAGGCTGGTGGATCACCTGAGGTCAGGAGTTCGAGACCAGC CTGGCTAACATGGTGAAACCCCATTTCTACTAAAAATACAAAAAATTAGCCGGGTGTGGTGGCACACACC TGTAATCCCAGCTACTCAGGAGGCTGAGGCAGGAGAATCCCTTGAACCCTGGAGGCAGAGGTTGCAGTGA GCCGAGATCGTGCCATTGCACTCCAGCTTGGGTAACACGAGCGAACTTCCGTCTCAAGAAAAAAAAAAAA AGAAAGAAAGAAAGAAGAAAACCAAAACCAAAACAAAACTCACAGATCTGTAAATATAAGGCCTAATTCT GGTCTGAAGTTCTCTGAGATTAGAAAGTTGGAGATGGGGGGTGGACAGTGCCTATGATGGTAGATGACAG TAATGAAGAATGACCAATTTCTACTGAGTGTCCGCTGTGCACCGGGTCTTGCATTAACGCACACCTGCTC GTGTGTTTGTGAAGGAGGGTCTATGGATACACCCATTTTCCAGATGAAGAAACTAAGGCTCAGAGTGGTT AACCAGATTGTCCAAGGTCACATCAAACCCATGTCATGCTCCTAACCTCCTTAGAAACTGTTTTTTGTTT TTTCTTTTCTTTTTTTTTTGAGACAGAGTCTCGCTCTGTTACCCAGACTGGAGTGCTGTGGCGTGATCAC GGCTTATTGCAACCTCCGCCTCCTAGGTTCAAGCAATTCTCTTGCCTCAGCCTCCTGAGTAGCTGGTATT ACAGGCGCCCACCACCACGCCCAGCTAATTTTTGTATTTTTAGTAGAGACAGGGTTTCACCATGTTGGTC AGGCTGGTCTCGAACTCTTGACCTCAAGTGACCCGCCCACCTCGGCCTCCCAAAGTGCTGGGATTACAGG CGTGAGGCACCGCGCTGGGCCCTGAGAAAATGTTTAGAGTCAGTGCTTGATTAAACAGGAATTGTCTTAT ACTTACATGCTCTGAGCACAACCCCATCTGCTTGTCGTTTTAAACCTAGAAAATAGTGGCTATTGGCTGG GCATGATAGCTCACGCCTGTAATCCCAGCACTTCGGGGGGCTGAGGCAGGTCTGTACAAAAAATTCAAAA AAATTAGCTCAGTGTGGTGGCACACACCTGTAGTCCCAGATACTCGGGAGGCTGAAGTGGGACAATCACC TGAGCCTGGCAGTCAAGGCTACAGTGAGGCAGGATTGAACCTCTGCTCTCCAGCTTGGGTGACAGAGTAA GACTCTGTCTGAGAAAAAAAAAAACAAAAAACAGTGGCTATTAATCTTCCCGTTTTCAAGGTGAGGAACT GAGGCCCAGAGAGGGGCCCCCTCTCTGGGCCTCAGTTCCTCCCATCCTCCTCCCCTCCCCGGGGCTAGAA AGCCGAAGCTGAGATTCAATCCCAGAGGCCAGCTGGATTTGGGAGACCTCAAATGCCAGGTCAGGCATAA GTTGCACTCTACCCACATCACCAAGTGTCCCCAGGAAAGCAGAAGTGTGTCCTCTTCCCTTTCCAGGTCT CACTTCCTGCTGCACATGGGCTAGGGCTGAAGAGTTCCAGTGGGAGGGTCACAGCCGTCCCAGGGAAAAG AGAAGTGGGAGCAGGCATGGGGAGACCAACTGTCTGTACCCATCTCCTCTCTGTCCTGGTAGAGGTTCCT CTTCCTGTCTGTCACTGCAGGTCAGAGAGCAGGCATGGTGACAGCCTCACCCCCTCCTCGTACCCACCAT CTGCCCCCACTCCTCCCCAGGTCTCATGGTGGTGTCATCTCCCTCCATGGGGGCTGTGTGACTTTGGGCA AGTTGCTGAACCTCTCTGGGCCTTGGCTTCCCTGTCTGTAAAATGGGGATGAGAAAAGAAATTGACCCCA TAGGGTGGTAGTGCGAAGTCAATGAGTTCATCCAGTAATGTGCTTGACAGAGAGCTTGGTACATATTTGG CACTCAAGAAATATTTGCTAGGCCGGGTGCCATGGCTCACACCTGTAATACTAGACCTTTGGGAGGCCGA GGCAGGTGGATCGCTTGAGCCCAGGAGTTTGAGACCTGCCTGGCCAACATGGTGAAACGCCATCTCTCCA AATAATTAAAAAATTAGGTGGGGCTGTCATTACACCACTGCACTCCAGCTTGTGTGACAGAGTGAGACCC TGCCTAAAAAAAAGAAAAAAGAAAAAGAAAGAAAGAAAGAAAACAAACGTTAGCTGTTGATAATTATAAT GTGCAAAGCAGTTTATATGCATCATGTCATTAAACCTTATACCCTGACAAGTAAGAACTGTGATGCCCAT TTTCCAGAGACAGAAACTGAGACTCAGAGAAGTTAAGACACTCACTCTAGGTCACACAGCAAACAACATC CAACACAGGACTTAGATCCAAGGAATCTGGCTTTAGAGCCCACACCCTGTGGCAGTAAACTCCTTCCTGA CATACTGTGTGGCTGTATGGCTGGAGTCTCCAGGGTGAAGGGGAAGCCCTTGGCTGCACCATTCCTGAGG CGTGGCTGTGAATTGTGTGGTTATGGGGGTTTTGTGGTTCCATGTGGCAGGGCTATACAGATGTGTACAC CAGTGGTGGCCCCCTCCACTCTGAGTGTGCCATTCCTCGGGTGGAATAGGTATGGGAACCTGTGCCGCTA TGCAGAGCTTGACACTTGTTGCCAGGAAACACACATAAAATAATAAGTGACAGGCCGGGCACGGTGGCTC GTGCCTGTGATCCCAGCACTTTGGGAGGCTGAGCGGGCAGATCACCTGAGGTAGGGAGTTTGAGACCAGC CTGACCAACATGGAGTAACCCTGTCTCTACTAAAAATACAGAATTAGCCGGGTGTGGTGGTGCATGCCTG TAATCCTAGCTACTCAGGAGGTTGAGGCAAGAGAATCACTTGAACCTGGGAGGCGGAGGTTGCAGTGAGC CGAGATCATGCCATTGTACTCCAGCCTGGGCAACAAGAGCGAAACTCCATCTCAAATAAATAAATAAATA AATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAATAAATGACAGTATGCACAAGCAGTC TTCTAAATGCTTACATGCCCCAATTCAGTCAACCCTGTGAAGTGGGGAGCCACTGTCATCCCATTTTACA GGTGAGAAGACTGAGGCACACAGCTAGGGAATGATAGAGCCTGGATTTGAGCCCCAGATCCAGCATCCGT GCTCCTCAGCACTAGGCTAAACTGCCTCTGTGCACAGACAAGAGGTATTGTTACCATTACTGATATTCTT ACCGCCAGTAGAGCAAAGACTCTGGGGACAGGATGGGGTTTAGGTCCCAGCTTCATCAGTGACAAACTGA TGACCTTGAACAAGTGATTCCGTCTCTCTGGGCCTCAGTGTTGTCATCTGTACAGTGGGAATAAGCATAA TGCTTACCACAGGACAACAGGATTGATGTGAGGGCCAAATGAATTCAGATTTGTCAAGGGCTAAGAAAGG CACTCAGTACATGTTGGACGTGTTTTATCTTTTTTTATTAAGATAATATATAACATAGTCAGGTGAGGTG GCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCAGGTGGATTACCTGAGGTCAGGAGTTTGAGA CCAGCCTGGGCAACATGGTGAAACCCTTTCTCTACACAGAATAAAAAAAAAGCCGGGTGTGGTAGCTCAC ACCTGTAATCCCAGCACTTTGGGAGGCCGAGGGGGGCGGATCACTTGAGATCAGGAGTTCAAGACCAGCC TGACCAACATGATGAAACCTCGTCTCTACTAAAAATACAAAAAAGTTAGCCAGGCATGGTGGCACATGAC TGTAGCCCCAGCTACTCGAGAGGCTGAAGCAGAAGAATTACTTGAGCCCAGGAGGCGGAGGTTGCAGTGA GCCGAGATTGTACCACTGCACTCCAACCTGAGTGACAGAGCAAGACTCTGTCTAAAAAAAAAAAAAAAAA AAAATTAGTCAAGCATGGTTGCTCACGCCTGTAATCCCATCTACTTGGGAGGCCGAGGCATGAGAATTGC CTGAACCTGGGAGGCGGAGATTGCAGTGAGCCGAAATCACGCCACTGCACTCCAGCTCAGGTGATGAAAT GAGACTCATAGGCCGGGCACGGTGGCTCACACCTGTAATCCCAGCACTTTGAGAGGCTGAGGCGGGCGGA TTGCCTGAGGTCAAGAGTTTGAGACCAGCCTGACTAACATGGTGAAACGCTGTCTCTACTGAAAATACGG CAATTAGTCGGGCGTGGTGGTACGCGTAGTCCCAGCTACTTGGGAGGCTGAGGCAGAAGAATTGCTTGAA CCTAGGAGACGGAGGTTGCAGTGAGCCAAGATCTCACCACTGCACTATAGCCTGGGCGACAGAGCAAGAC TCCCTCTCCAAAAAAAGGAAAAAAAAAAAAAAAGAAAAAGAAATGAGATGTATAACATGCATAATCTTCA GTGTACCTCTAGATCAAGCTCGTCTAACACATGTGGCCCAGGATGGCTTTGAATGCGGCCCAACATAAGT TCGTAAACTTTCTTAAAACATTATGAGATTTGTTTGTGATTTTTTTTTTTAACGCATCAGCTATCGTTAG TGTTAGCGTATTTTATGTGTGGCCCAAGACAATTCTTCTTCCACTGTGGTCCAAGAAAGTCAAAAGATTG GACACCTTTGAGATTGTTTAACACACATATTCACCATGTAACCACCATCCAAATCAAGACACAGACCCTT CCAGTCCCCAAGAAGTCTCCCTCAGGCCCCAGAGATGGCCACCCTTCTGCTTCTAGAACATTGCTTTTGC CTGTAGTATAATGTCATATAAATGGGGCCTCACAGTATCGTGCTATTATTATGATGATCATTACTATTAT TTGAGACAGAGTCTTGCTCTGTTACCCAGGCTGGAGTGCAGTGGTGTGATCTTAGCTCACTGTAACCTCT GCCTCCCAGGTTCAAGTGGTTCTCCTATCGCAGCCTCCCGAGTAGCTGGGATTACAGGCGAGCGCCACCA CATCCAGCTAATTTTTTACATTTTTGGAAGAGATGGGGTTTCACCACGTTGGCCAGGCTGGTCTTGAACT CCTAACCTCAAGTGATCGCCCACCTTGGCCTCCCAAAGTGCTGGGATTACAGGCGGGAGCCACCGTGCCC AGTCTATTTGCGTTATTATTGTCATCACACTATTATTATCGGTGCTGACCACCCGCCATGCACTGTGGCA TCCTTTGGGCATAACTACACTTAATCTTTAAACAATCCTGTAAGGCACTTGATCCTCTAAGGCCCCGTGT GCCCAAGGAAAAAACTGAGGCTCAGAGAGGGAAGAGTCTTGCCAGAGGTGGCTTTTGGAAGTGGTGACAG AACCACATTGTATACAGCCAAATGATCTCCTTGCTTTGCAAATCCAGGTGCCCGTGTTATCCTAGCATGG CACTGCAACACACACGCACCCTTGAAAAGTTGTGTAGTCACACCAGACCACCACCACTGGGAGCTGTGTG ACCATCTCGTGTGATTGCTTGGCTGTCCCGTCCTCACACCCTTGCCTCTCCTCAGGCTGTGCTGTCAGAC GATGGGATGGGCATCCAGGCGGGAGAACCAGACCCCCCAGAGGAGCCCCTCACCTCGCAAGCATCCGTGC CCCCCCATCAGCTTCGGCTAGGCAGCCTCCATCCTCACACCCCTTATCACATCCGCGTGGCATGCACCAG CAGCCAGGGCCCCTCATCCTGGACCCACTGGCTTCCTGTGGAGACGCCGGAGGGAGGTAAGAAGGGTTGG GGAGGGACACGTCACCACTGCCCCACCGGACCTTGCTTATATCAGTGCCACCCCCATTGTCCCCTTTCAC TCCTTTACCCCTCATGGCCTCAATCTCCTTCCCATCCAATCTCTGACCCCTCAGCAGCACTGCCCGCTGG CCTCTCTCCCAGCCCTTCTCTCCCCTGTGCTTCCTCTCATGGGAGGCCTGCACGAGTTGCCCACGTGTGT GCCCTTGGCACCCTGCACCCACTTCCTGGGAACAGGGGAGGGGGTCAGGAAGAGGTGGGGGTGCCAGCTT CCCCTCTTCCCTGTCCTCCAGTGCCCCTGGGCCCCCCTGAGAACATTAGTGCTACGCGGAATGGGAGCCA GGCCTTCGTGCATTGGCAAGAGCCCCGGGCGCCCCTGCAGGGTACCCTGTTAGGGTACCGGCTGGCGTAT CAAGGCCAGGACACCCCAGAGGTGGGTGCTGCTGGTGGGATTGGAGTGGAGTGGCTTGGGGAGGAGGGAG GAGAACATATCAGGGCAGACATAGATGGTTGTGAAGGTTGGGTAGTACACAATTGCTCTATGCCTAGGGG GCACATTCAGGGAAGGTTCACATTCACATTCTGGGGAGAATAAGGGGGTCTAAGGGAGGGCATGGGGAAT GGCTGTTTTTGAACCACTGCAAAAGCATTTCAGCAGACTCATATTTACTATATAACGATTTTACAGCAGA TAGTTATATAGCACCTTGGGGAAGGGGTACCTTTTCCTGATTTTCACAAAGGCACTCCTATCAGGGCTAG CAATACCCTGACATAGGGAGGGAGGATGGAAAGGGAAGCTAGAAGGGGATGGAGGGATACAGGTTAAAGG ATGAGGATGAGAGATGAAGGGGAGGACGAGGAAGGATGAGGAGTTGGAGGATGGGGAGAGCGTTTTGAGA AAGAGATGGGGCATTGAGCCCGAGAGTGAAGGCTTAACAGCTGGGGGGTAAGGTTCTACCCTGATGCCAC TTCTGGACCTCCTAGGTGCTAATGGACATAGGGCTAAGGCAAGAGGTGACCCTGGAGCTGCAGGGGGACG GGTCTGTGTCCAATCTGACAGTGTGTGTGGCAGCCTACACTGCTGCTGGGGATGGACCCTGGAGCCTCCC AGTACCCCTGGAGGCCTGGCGCCCAGGTAAGTCCAAAGCCATGCCCAACCTGCTTCAACCCTGTCTCTCC CTGACAGCCCTGACTTACTCCTTGTACCTTTCAGTGTTACCGCAACTTAGGCCCTGTTCCTACCCTGAGC CTTACTGAGAGCTGCCCTCACTCCCTTACCCATGCCAACCCCTCACTCCCTTACCTGTGCCACGGCCTCA CTCCTTTACCCGTGCCACACCCTCACTCCCTTACCCGTGCCACACCCTCACTCCCTTACCCGTGCCAAAC CTTCACTCCCTTACTCGTGCCACACCCTCACTCCCTTACCCGTGCCACACCCTTACTCCCTTACCCGTGC CACGCCAGTCTTGTCCTCTCTGAGCACATCTCCTCTCTGTCCTTTCTTCTCACAGGGCAAGCACAGCCAG TCCACCAGCTGGGTAAGGGCTTCCACACCCCATCTCCTCCTTCCCTACCCTCAACACCTAGTGGGGGCAC TGTCACCATGCATACTCATTGCACATCCCTTTCATGTTTCTCTAACTCATCACTCTAACCTACTTCTTGA GTTTGTGTGGTCCTTGATGGAGGTGCCTATAATGGCCTAGCATAGCACATTGTAGGTATTCAGGCAATGA CAGATGAGTGGGTGGATGGATGAACAAATAGATGGATGGATGGATGGATAGATATATGGAGGGTGGATGG GTGGGTGGGTCAATGGATGAATAGAGGATGGATAGGCGGGTGAACAGATAAATGACTGGATGTCGAGTGG ATAAATGGATGGGTAGATGGATGGGTGGATGGATGGATGGGTGGATATATGGAGAATGGATGGGTGTGTG GGCCAATGGATGAATAGAGGGTGGATAGGTGGGTGAACAGATAAATGACTGGATGGTGAGTGGATAAATG GATGGGTAGATGGATGGGTGGATGGATGGGTGGGTGGATATATGGAGGGTGGATGGATGGATGGTTGGAT ATATGGAGGGTGGATGGGTGGGTGGGTCAATGGATTAATAGATGGGTGGATAGGTGGATGAACAAAAGAT GACTGGGTGGTGAGTGGATATATGGATGGGTAGATGGGTGGATGGATGGATGGATGGATGGATGAATGGA TGGTTGGATAAATGGATGGATGGACAGATGGATGGATTTGTGAGTGGATGAATGGATGGGTAGAAAGGTG GATGGATGGATGAATGAGGTATCCTCCTCACATCCATCCCTCTCAAATATTTCTCTAACAATTCTCAAAC ATTCCTCCTACACCCATTGTCCCCTCTGGGCACTATTATGGTTCACTCTTGTAACTCAACCCACTAGCCT TCAATACTCCTCACATCCCTTCCTACATTTCTTCACATACGCTTTCCACGCTTATTCCACCCTCCTTTCA CATATATCCCATTATAATCCGTTCCTCCCACATGACCCCAAAGGCCCATTGCACAACACACTTCTCATTC ACAAACTCTGCACACCTTGTATGCACTTACCATACCTTCCACATTGCAAACACTGAAAAACATTGTCCAC AACTTTCCCACACCCGATTCTCCTTGCATGCTTACTGCACACTCCATAGACATCATTCCCTCACCCTTCA CTAATCCCAACCCATCTCACTCTGCACACTCACCCTGAACCCCTTGCATACTCAGCACATAATGATCTTT ATTTCTTACACACTCCATTCCACCCCTGCCCTTTTTACACCCCCTTTCTGTGCACCCCATACTTCTCATC TGCCCTTCTAACATCTTTTGCATGCTCACTGCACACTTCTCTCACACTGCAATTACATCCTTAAAATTCC TTGCTCACTCCTTGTATCTAAGACTTCACGAATACTCTTCCCACTTCACACACCCCCAACTTTTCCAGCA GCCATCCAACCCTGTATATGCTTACCATGCCCCTTTGGATATTTATTTCACCCTCATTCCTGGCTTTATG GAAACCATTGTGGCCGGGTGCAATGGCTCACGCCTGTAATCCCAGTACTTTGGGAGGCCTGAGACAGGTG GATCACCTGAGGTCAGGAGTTCAAGACCAGCCTGGCCAACATTGGCGAAAACCCATCTCTACTAAAAATA CAAAAATTAGCTGGGCCTGGTGGTGCGAGCCTGTAATCCCAGCTGCTCGGGAGGCTGAGGCACAAGAATT GCTTGAACCTGGGAGGCGGAGGTTACAGTGAGCCAAGATCATGCCACTATACTCCAGCCTGGGCAACACA GCAAGACTCTGTCTCAAAAAAAAAAAAAAAAGAAAGAAAGAAAGAAAAAAAGAAAGAAAAGAAAAAGAAA AGAAAAAAAAATTAGCCAGGTGGCACAGACCTGCAGTCCCAGCTACTCAGGAGACATGGTGAAACCCTGT CTCTACCAAAAAAAGAATACAAAAATTAGCTGGGCATGGTGGTGCACACCTGTAATCCCAGCTACTTAGA AGCTGAGGCAGGAGATTTGCTTGAAACTGGGAGGCAGAGGTTGCAATGAGCTGAGACCGGGCCACTGCAC TCCAGCCTGGGTGAAAGAGTGAGACCCTGTCTCAAAAAACAAACAAACAAAAAAAGAGACAAAGAAAACC CTTTTGTAGTCATTGCATTCTCTTCAAAAGATGTTCCTTAGTCCGCCCTCCTTGCACACGCTTCATGCAC CATCCTACACTGCAAGGATCTTCTTCCCCACTCACCTGCTTATCTACACTCTAGTCCACCCTTCTTGCAC AATCATCACATTTCTCACACTAACCTATGCTGCTTGAGATTTCTCCACACCCATCTCATGTTCATCTAGC CCTCTTGGCACACTCATAACGCGTTCCACACATCTCTCCCTCCCATTCCACACTCACTGCACACTCCTCA AATATCCATTCCACTCTTCTGTTTTTTTGGATCTTGGTGGCATAATATTTGGTAGCTTAAAGTAAGGAAA ACTGCAAACGCCCAAACAGAGACTTGAACCCTGAACCCTCAGGTTAAAAGTCTGATGCTCTACCACCTGA ACTATCCTGGCACTCTCTTTTTTTTTTTTTTTTTTTTTTTTTTGAGATGGAGTCTTGCTCTGTCACCCAG GATGGAGTGCAGTGGCCCAGTCTCGGCTCACTGAAACCTCCACCTCCCAGGTTCAAGCAATTCTCCTGCC TCAGCTCCCGAGTAGCTGGGATTGCAGGTGTGCACCACCACCCCAGCTAATTTTTGTATATATTTTGTTT AAGTAGAGACAGGGTTTCATCATGTCGGCCGGGCTGGTCTTGAACTCCTTGCCTCAAGTAACCCACCCGC CTTGGCCTCCCAAAGTGCTGGGATAACAGGCATGAGCCACCACACCTGGCCTCCATCCCACTCTTAACTC ACCCATCCTACAACTTTCACACACTTCTGCTTTAACCTGCACTTGTATCACATCCATTGCATGCCCTGTC CAGCCCAGCCCATTCAGATATGTGAATGCATCCATCACACACCTCATCAAGTATGTGCACATCTTTGCCG AGGCCTTCTGCCTCCCTCCCACATCACCCCTTTGGGTCCCAGAGAGCTGGATCCAAGGCTTCATCCATGA CCTGTTCCTCATACCCCCTGATAGTGAAGGAACCTTCAACTCCTGCCTTCTCGTGGCCCTGGTGGTATGT ACTGCTAGGAGCAGTCGTGGCCGCTGCCTGTGTCCTCATCTTGGCTCTCTTCCTTGTCCACCGGCGAAAG AAGGAGACCCGTTATGGGTGAGTTGGAACCACATGGGGAGGCTGTGTGGCCTGGGATGGAGAGGCTGGAG GCAGGGAGGCCAGTGAGGAGGCTGGTGCAGGAGGAGTGATGACTAAGAATCAGAATGAGGGCAAGGGAAG CCAGGCGTGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCTGAAGCAGGTGGATCACTTGAGGTC AGGAGTTTGAGACCAGCCTGGCCAACATGGCGAAACCCTGTCTCTACTGAAAAATGCAAAAATTAGCGGG AAGTGTAGGCACACGCCTGTGGTCCCAGCTACTTGGGAGGCTGAGGCACGATAATCACTTGAACCCGGGA GATGGAGGCTACAGTGAGCTGAGATCGCATCACTGCACTCCAGCCTGGGTGACAGAGTGAGATCCTGTTT TCAAAAAAAAGAATGAGGGCAAGGGGGTGTGTGGAATGAATGGAAGGCAGAAGGTAGCTGCCCAAGGCAT GCTCAGCAAATGTTAGCACAGAGGGCAGGCAGGGCTTGAGGCTGAGATGGTGCTTGCTCAACTGCTGGTT GAGTAGGGGGTTCCACATGGTTTTTCCCTGCCCTCACCTACTCCCCCTCCCCCCCAGAGAAGTGTTTGAA CCAACAGTGGAAAGAGGTGAACTGGTAGTCAGGTACCGCGTGCGCAAGTCCTACAGTCGTCGGACCACTG AAGCTACCTGTAAGTGAACCCTATGCCCCACTGCCCTGGCCTGGATCTAAAGGCTGTAGAGAATCTGGCC TGCTGGGCTTCTGTACATGTGTGAGCCAAAAGTTTCTAAAGGCCTTGGGATACTAGAATGTCAGAACCAC AGACCCTAGAAATAACAGATTTGTGGAACCACAAAGAACTTTCAAGGAATAGAATCTTAGACACAGTAAA TCTTAGAAACACCAAGGCTGGGTGTGGTGGCTCATGCCTGTAATCCTAGCGCTTCGGGGGGCCGAGGTGG GAGGATCACTTGAGCCCAGGAGTTCGAGAACAGCCTGGGCAGCATGGTGAAACCCTGTCTCTACAAAAAA AAAAAATTAGCCAGGTATGGTGGTGTGCCCCTGTACTCCCTGCTACTCGGGAGGCTGAGGTAGGAGGATC ACCTGAGCCCAGGGAGGTCAAGGCTGCAGTAAGCCGTGATCACACCACTGCACTCCAGCCTGGGTGACAG AGCAAGACCCTGTCTCAAAAAAGAAAAAAAAATAAAAGAAAGAAAAGAAACACCAAACCTCAGAGCCATT GGATCTTAGAAGATGTAATGATGATGATAATGATGAAGATAATGACAAGAAGAAAATGATGATGATGATG AAATAATGTTGAGATTAGATGGTGATGATGTGATAAAAATCACAGGCAACCCTAGCACTACCTATGTGGC AGGCTCTGTTCTAAGCATTCTACATGTATCTCCTCGTTTAACCCTCAGAGCAACCCAAGGACACGGGTTT CTTTTTTCTTTTTTTTTCTTTTTTTTTTTGAGACAGAGTCTCGCTCTGTTGCCCAGGCTGGAGCACAGTG GCACAATCTCAGCTCACTGCAACCTTCACCTCCCAGGTTCAAGTGATTCTTATGCCTCGGCCTCCCGAAT AGCTGGGATTACAAGTGCATGGCACCACATCTGGCTAATTTTTGCATTTTTAGTAAAGATGGGGTTTTAC TAACCCTGTCTTTGTTAGCCAGGCTGGTCTTGGAACTCCTGGCCTCAAGTGATCAACCTGCCTTGGCCTC CCAAAGTGCTGGGATAACAGGCGTGAGCCACCACGCCCAGCCAGAGGTGGGTTTCTTATCACCTTCACTT CACAGATGAGGAAGCTGTGGCATAGAGTGGTTAAGTCACTTGCCCAAGGCCACACAGCTTGTAAATTGGA TAGCTGGGATTTGAACCCAGGTACTTTTGCTCTGAAGTCTATACTATTTTTTTTTTTTTTTTGATAGAAT CTTGCTCTGTCACCCAGGATGGAGTGCAGTGGCTTGATCTTGGCTCACTGCAACCTCCGCCTCCTGGATT CAAGCGACTCTCCTGCTTCAGCCTCTCAAGTAGCTGGGACTACAGGCACATGCCACAACGCCTGGCTAAT TTTTGTAGTTTTAATAGAGACAAGGTTTCACCATATTGGCCAGGCTGGTCTCGACCTCCTGAACCCGTGC CTCCCAAAGTGCTGGGATTACAGGTGTGAGCCACCACGCCTGGCCTGAAGTCTATACTCTGAACTGCCAC ACTCTACTACCTCTTGGAATTATAAATTGGTAGAGAGATAGAATCGATCTTGGCCTGAAAAATTATATGC ATGTACTCTACACCCTTATACTTTTGAAATCATAAAATCTTAGAACTATAGACTCTCCATTAGAAGGCTG GAAAGCCATGCAAGGTCTCAGCCGAGGAGGGGATCTCAGAGGCCCAGTCAAATCTGTTCTTTCGGCTGGG TGCAGTGGCTCACGCCTGTAATCTCAACACTTTGGGAGGCCCAGGCGGGCAGACACTTGAGGTCAGGAGT TCGAGACCAGCCTGGCCAACATGGCGAGACCCTGTCTCTACTAAAAATACAAAAATTAGCCAGATGTAAT CTGTAATCCCAGCTACTTGGGAGGCTGAGGCAGGAGAATCTCTTGAACCTGGGAGGCGGAGGTTGCAGTG AGCCGAGATCGTGCCACTGCACTTCAGCCTGGGTGATAGAGCAAGACACCGTCTCAAAAAAAAAAAAAAA AAAAAGGAATCTCATCTTTCCAGTTAGGGAAACTGAAATCCAGAAAGAAAATGGAAGAGCTAGGTCTCTT CCTAGCATACAGCGAGAAAGCCGCCAGGGCCCCAGGGGGATGTTTGGAAAGGGCTGGGAAAGACATTTAT TTAAGAAGAGAAGGAAGAAGCAACGATGTCCCAGTGATTTAACTGAGTAACATACAGCATCCATTCTCAG GGTGTGAGCCTGGTCCCCTGTGGTCCCTGAGACCTTTGCAGGGGGCCCATAAGGTCAAATCTATTTTCAT ACTATTACCAAGACATTATTTGCCCTTTTGCTTTCTCATTCTCTCATTAGCATTCAGCGCAGTTTTCCAG AGGCTCCCTGACGTGGGATGATGTCATCCAACACTCTGACAGCTGATGGACCTTGTGCTTGTATATTCTT GTTTTAAAAATTTATCAGGCTGGGCATAGTGGCACATGCCTGTAATCCCACCACTTTGGGAGGCCAAGGT GGGCAAATTGCTTGAGGTCAGGAGTTTGAGACCAGCCTGACCAACATGGTGAAACCCCATTTCTACTAAA ATACAAAAATTAGCTGGGTGTGGTGGTGCATGCCTGTAATCCTAGCTACTTGGGAGGCTGAGGAAAGAGA ATCGCTTGAACCCGGGAGGCGGATGTTGCAGCAAGCTGAGGTTGTACCACTGGACTTCAGCCTGGGCAAC AGAGTGAGACTGTCTCAAAAAAAAAAAAAATTAAATAAACCTGATAGGTTTTCTTTTGAGGCCAGGAGTT TGAAACCAGTGTGGGCAACATGGCAAAACCCCATCTCTATTTAAAAAAAAAAAAAGAAACACAAAAATTT GCCAGGTGTGGTGGTGTACACCTATAATTCCAGCTGCTCAGGAGGGTGAGGCAGGGGAATCACTTGAACC TGGGAGGCGGAAGTTGCAGTGAGCTGAGATTATGCTACTGCACTCTAGCCTAGGCAACAGAGCGAGACTC GGTTTCAAAAAAAATTTTTTTATTTTTTTAGAGATGGGGTCTGGCTATGTTGCCCAGGCTGATCTCCAAC TCCAGGCCTCAACTGGTCCTCCTTCCTTGGCCTCCCAAGTTGCTGGGTGAACCACTGTGAACCACTGTGC CCAGCTAGTTTTATTTTTGAATACAGAAATATTGATATATATGTAACATAAACAAAAGCTCTTTCTAGTC CTCAATAATTCTAACAATGTAAAGGTGTCCTGATGTCAATTTGTTTGAGAATGATTATATAACAAAGAAA ATGGATAAATTACAATTACACTCAACAACTAAATTAAAACTATTTCATAGACATCATGTTGAGTGAAAGA AGCCAGACACAAAAGAGAATATACTATGTGATTCCATTTTTATAATATTTCAAAACTAATCGATTGTAAC AGAAATCAAGAAAGTGGCTACCCCAGGAGGGCAGGTCATGTTCTGTTCTTGGCCTGAGTGCTAGTTACAC ATTTGTGTTTGATTTGTGAAAATCCACTGAGTTGGCCAGGCGTGGTGGCTCACGCTTGTAATCCCAACAC TTTGGGAGGCCAAGGTGGGCAGATCACCTGAGGTCGGGAGTTCCAGACCAGCCTGACCAACATGGAGAAA CCCCGTCTCTACTAAAAATACAAAATTAGCTGGGCGTAGTGGCACATGCCTGTACTTGGGAGGCTGAGGC AGGAGAATCGCTTGAACCTGAGAGGCGGAGGTTGCGGTGAGCCGAGATTGCGCCATCGCACTCCAGCCTG GGCAACAGGAACGAAACTCCATCTCAAAAAAAAAAAGAAAAGAAAATCCACTGAGTTGCTTACTTATGAT TTGTGCAGATTATACTTCAATAAAAAGAAATATTTTTGTGTGTGTGTTTTGTTTGAGATGGGGTCTTGCT CTGTCACCCAGGCTGGGGTGCAGTGGCATGAGCTCAGCTTACTGCAGCCTCCACCCCTGGGCTCAAGTGA TCCTCCAACCTCAGCCTCCTGAGTAGCTGGGACTATAGGCGCGTACCACCACACATGGCTAGCTTTTGTA TTTTTTTGTAGAGACGGGGATTCGCCATGTTGCCCAGGCTGGTTTTGAATTCCTGGACTCAAGTGATCCA CCGGCCTCTGCCTCCCAAAGTGCTGCGATTACAGGCATGAGCCACTGCATCCAGCAAAAAGAAATATTTT TATTTTATTTTATTTTATTTTATTTTATTTTATTTTATTTTTGAGACGGAGTCTTGCCCTGTCACCCAGG CTGGAGTGAAGTGGTGCGATCTCAGCTCATTGCAACCTCTGTCTCTTGGGTTCAAGTGATTTTCCTGCCT CAGCCTCCCCAGTAGCTGGGACTACAGGCATGTGCCACCACACACGGCTAATTTTTGTATTTTTTTGTAG AGACAGAGATTCGCCATGTTGCCCAGGCTGGTCTTGAACTCCTGGACTCAAGTGATCCACCTGCCTCTGC CTCCCAGAGTGCTGGGATTACAGGCGTAAGCCACTGTGCCCAGCAAAAGAAATATTTTTAACAACTGGTA CAGCAGGGCACTGACCCATCAGGGTGCCCACTGGAGCAAGAGCGTGGCCAGGCTTTACCCCTTGAGTTCC CTTTGAGGGAAGGTTCAGGGGGTCCAGAGGAGGAGCTGGGGTGGAAGTAGAGGGGTGCTCAGGGCAGTTG CTAATTTTAAATCAGTGCAGAAGTATGTCAGTGTTTCAACAATGGATCTATCCCTACTGGTGGGTGAATG TCACCTGAATGTCAGCCCTGCTCCATGACTCTGTCCACCCCAACCTTGCATGCAGTGAACAGCCTGGGCA TCAGTGAAGAGCTGAAGGAGAAGCTGCGGGATGTGATGGTGGACCGGCACAAGGTGGCCCTGGGGAAGAC TCTGGGAGAGGGTGAGTCCCCCGGCAGCATACACACATCCTTCTGAACTTCTGAGATCCTGCACTTCCAC ACTCCCACCCAACTATAGGAAATACAGTCCCCACGGGCCCTCTGAGGTCAGTGTCTCCCTCTGGCCCCCC ACAGGAGAGTTTGGAGCTGTGATGGAAGGCCAGCTCAACCAGGACGACTCCATCCTCAAGGTGGCTGTGA AGACGATGAAGAGTGAGTTACGTGCACATGTGTAGGACCCCCAGCTCCTTCCCTATGCCCCTGAGACAGA AGAGAGCAAGCAAGTTAGCCATAGCTTAGAACTTCTGGTGTTTCCAGATAGGCAATGGAGCCCCTGCCAG GTACCTCAATAGAAGGAATTGAATATGGGGAGATTAGTACAAAGGTGGGAGACGGGTTGAAGGAACAACT GGGGGCAGGGAGGGAAACCAGAGATGAGCAGCAGCAGGAAGTCACTTCCCCCGCTAGGCCTGAAGGGTAG AGGGAGCAAGTGGTGTTACCAGAATCCACAGCTAGGGACACCAGGCAGGAGCTGGTATCACAGAGTTAGA GGCTGCTCTGTGGGAGCTAAAAACCCAGAATAGCACTTTGGGAGGCCGAGGCAGCAGATCGCTTGAGTCC AGGAGTTTGAGACCAGCCTAGGCAATATGGTGAAACCACATGTCTATGAAAAAAAAAATAATAATAGTAA CAAAAAATTAGCTGGGCATGGTGGCACACGCCTGTAGTCCCAGCTACTTGGGACACTGAGGTGGGAGAAT CACTTGAGTCTGTGCGGCAGAGGTTGCAGTCAGCTATGATCATGCCACTGCACTCCAATCTGGGTGACAG AGTGAGACTTTGTCTTAAAAAAATAAAACACACATGGCTGGGCGTGGTGGCTCACGTCTGTAATCCCAGC ACTTTGGGAGGCCAAGGCGGGTGGATCACATGAGGTCAGGAGTTCGAGACTGGCCTGATCTGCATAGCGA AACCCCACCTCTACTAAAAATACAAAAATTAGCCAGGCGTGGTGGCAGGCACCTGTAATCCCAGCTACTC GGGAGGCTGAGGCAGGAGAATCGCTTGAACCTCACAGGCGGAGATTGCAGTGAGCCGAGATCGTGCCACT GCCCTCCAGCCTGGGCGACAGAGCAAGACTCCGTCTGAAAAAAAAAAAAAATTAAAACACACACACGCAC ACATGGGCGACACAACCACCACCAAGGGAATACCAGAAGCAGAGAGAGGGTGAAATACCCTGGCTTCTCC CTTTCTCCCCGCTACCTGCCAGTCTCCCATAAGGGCCTACCTCCCATTGGCAAATCCCAAGAGGAAACCA CTAGGAAAGGGAGCCTGGGAAATGTAGTTTTCAGGGGCCGGCCCACTGTGATACATAGTGGAGCAGGAGA AGCTCTAGAATGAGGCATACCTGGCTGAATCATTTACCAGCTATGCGATCTCAGGCAAATGACTTTCCCT CTCTGAGCCTCCCACCTGTCATCTGGAAAAAAGGACCCTAATGTCCCCACCTTCCAAAGCTGTTTTGAGG CAAAGCACTTCATGCTGAGGGTGGCAAGTAGGACATGCTTGTTAATGTGGAGTAGGACTATATTATTTCC ATTATCAGAGAGGGCAGGAGCCATTTCAGGGTTACACAGCACAGGAAGTCCAGGGCTAAGTTCTTCACAC ACAGGGAAGGAGAAGCATAGGGCATTCAGATTGGGGCTGGTGGTGAATAGAGAATGATCCTTTCTGAATT ACAGGGCTTAAAAGCTTGGGCTATGAAGTCATTACCCACTCATTCGTTCATTATGGAGCACCTCCTGTGT ACCAGGTTATTTTGTTTGTTTTGCTCTGTTTTGTTTTGTTTTGAGGAGGAGTCTCACTCTGCTGTCCAGG CTGGAGTGCAGTGGCATGACCTCAGCTAACTACTACCTCTGCCTCCCAGGTTCAAGCGATTCTTCTGCCT CAGCCTCCTGAGTAACTGGGACTACAGGTGTGCGCCACCACGCCCAGCTAATTTTTGTGTTTTTAGTAGA GACGGGGTTTCACCATGTTGGCCAGGATGGTCTCTATCTCTTGACCTCATGATCCACCTGCCTCGGCATC CCAAAGTGCTGGGATTACAGGTGTGAGCCACCACACCCAGCCTACGTTTTTTGTTTTTTGAGACAGAGTC TTGCTCGTTGCCCATGCTGGAGAGCAGTGGCAGGATCACAGCTCACTGTAGTCTCAACCTCTGAGGCTCA AGCGATCCTCCCCACTCAGCCTCCCACTGGTTATAGTCTTGGCCTGGGTCTGAATCTCAGCCGTGCAACC TTGGGCAAGTCATTTTGCCTCTGTGAGCCACAGTGTCCTGAACTGTTAAATGGGATGATACTTGTTTGGG TCCCCAGGGCAGGTAGGGAAGTGCTGGGAAGCAGCCTGGGCAGTTGTGAGCAGGTGGACCCTGGAGCCAG ACTGCCCGGGTTTGAGATCTGCCTCTTCCACCTCCAAGCTGTGTGTTCCCTTAGGCAGACTCCTAACCTT TTTGTGCCTTGCTTTCTTCATCTTTAAAATAGAGATAGGCCAGGGACAGTGGCTCATGCCTGTAATCCCA GTGCTTTGGGAGGCCGAGGTGGGAGGATCACTTGAGGCTGGGAGTTTGAGACCAGCCTGGACAACATAGC AAGACTCCCTCTCAAAAAATTGGCTGGGCATGGTGGCTCACACTTGAAATCCTAGCACTTTGGGAGGCCA AGGCAGGCAGATCACTTGAGGTGGGGAGTTTGAGACCAGCCTGGCCAACATGGTGAAACCCCGTTTCTAC TAAAAATACAAAAATTAGCTGGGCATGGTGGTGCATGCCTGTAATCCCAGCTACTCGGGAGGCTGAGGTA CGAGAATCTCTTGAACTGGGGAGGCAGAGGTTGCAGTGAGCCAAGATTGCGCCATTGCACTCAAGCCTGG GGGACAAGGGCGAAACTCCATCTCAAAAAAAAAAAAAAAATTATCCGGGATGGTGGTGCGTGCCTGTGGT CCCAGCTACTCAGGAAGGCAAGCCTAGGAGTTCGAGCCTAACCTCCAGTGAGCTATGTTTGCTGTGATTG CATCCATCCTGGGTGACAGCGCAAGACCCTGTCTCAAAAAATAAAAATAAAAAACAAAAACAAAAACAAA ACAAAACAAAACAAAAAACCAATAAAATGGGAATGATAATAGTAGCACCTGAGAAGATTAAATGAGTTAA TATATATAAAGTTGGCCAAGCGCAGTGGCTGACGCCTGTAATCCTAGCACTTTGGGAGGCCGAGGCGGGC AGATCGTGAGGTCAGGAGATCGAAACCATCCTGGCTAACAAGGTGAAACCCCGTCTCTACTAAAAATACA AAAAATTAGCCGGGTGTGGTGGCACACGCCTGTAGTCCCAGCTACTCAGGAGGCTGAGGCAGGAGAATTG CTTGAACCCGAGAGGCGGAGGTTGCAGTGACCCGAGATCAAACCACTGCACTCCAGCCTGGACAACAGAG TGAGACTCCATCTAAAAAAAAAAAAAAAAAGAAAATATATATTTTATATATATATATATATTATATACAC ACACACAGACACACACACATACACATATCACATATAAAGTGCTGAGTATGGTGCCTGGTACTTACTAATC ATGTTTGATGAAGATGAGTGATGATGATGATGATGATGATGATGGAGTGGAGGTGGAGGGAGAGTCCTCC CTCTCCTCCCCTCCTCCTCACGACCTTTCTCTCTCCCTCAAGTTGCCATCTGCACGAGGTCAGAGCTGGA GGATTTCCTGAGTGAAGCGGTCTGCATGAAGGAATTTGACCATCCCAACGTCATGAGGCTCATCGGTGAG AGAGGGGCAGATTCAAGGGGTCTACAAGCCCCATGGGGGCCATAGCAGAGGGAAGAGCCCTGCTTCTGGC CCTGGGAAGATCAAACTTCCAGGCTTCCTGCTCCCCGCTCCTTCAGGGTCAGCAGGCTTCCCCCTCCTAG TCTCCCTCAGCTTGGAATGTGACCTCTGATCATTCCCAGAAATAGCTGAGGTCCCCAGGAGGGCTCCGGA AACGTCCCTGGGAACTCTGCTGGAAACAGCTTCTCTGCAGCTTGGTCCTTGCCACTGCCACTACCCCCAA ACAATATGGTGGCCAGATTGGATGGGTAGTGAGAAGGAGAGGCTGGAGGCTGGCTGGTGGGGGGCTTGGC TTCCCCTTCTGCCCAGCAGGAGTGACAGGGCTACCTGGGGGGCTCAGGTGTCTGTTTCCAGGGTTCTGAA CGAGAGAGCTTCCCAGCACCTGTGGTCATCTTACCTTTCATGAAACATGGAGACCTACACAGCTTCCTCC TCTATTCCCGGCTCGGGGACCAGCCAGTGGTAAGGGGCGTTTAATCATTCAGTCTACAAATATTAACTGA GCATCTATCAGGTACCCAGTGCTGCTCAGACCCTGGGAAGACCACGGTGACCAGGAGCTTGCTCTCCTGG AGCATTTCTTCCAGCAGGGGAGGGGCGGATGATAAACAAGCTAATAAATACCTAAGCGAGATGATTTAAA TGTTTAAGTGCTAGGAAGGAAATACAGTAGGATGGAAGATAAGGAGGCCAGGCAGTGAATTTGGGTGGAC GTGGAAGATCTTGCCGAGGAGGTGACCGTGAAGGAGTTGGGGCTGGGGAGATGTCTGGAGATCTGGGCAG GAAGCGACCCCAACAGAGCGCACAGCATAGGCAAAGGCTCGGAGGTGGGAATGATCATCGTTTGTCTGAA GACCAGACAGGAGTCTGGTGGGAGTGTCAGTCAAGGGCAAGAACATAGGCAATCAAGTCCAAGAGGAAGG CTGGAGCAAGTTTATAGGACCTTGCAGGCCATGGAGAGGGGTTGGGTTGAATTGTCAGGGCCATGGGAAA CCACTGCGGGCAGAGCTAGGCTTGCACAGAGGGATGGAGGGAGGAGGGATCGCATCAAGGACTCTGTTGA CCTCTCCTCCCACCTGCCTTGGCTCCCCAGTACCTGCCCACTCAGATGCTAGTGAAGTTCATGGCAGACA TCGCCAGTGGCATGGAGTATCTGAGTACCAAGAGATTCATACACCGGGACCTGGCGGCCAGGAACTGCAT GTGAGTGCCTTTCAGGGACCCCCCCCCCCCAACTGCTCCTGCACTCCCTGAGGGAGTTCCCTCCCTCCTT CTTAGGATGGAAGCAGGGCTAGACACCCGCTGAGGGCAGGTCAGAACTCAGGACCAGGAAAGTCAGTAAG GGGGTCTGGGAAGGCTTCCTGGAGGAGGTGAGTCCTGAACTGAGATCTGGAAGGAGCATTTGGATGCGGA GAGGGAAGAGACCAGAAGGTGGGCTCAGTGCACAGCATGAGGTGAGCAAAGGGGCTGAGGTGACCGATGG GGGTGGGGACACGTGAGCTGCATCTCTGTCCCACTCCATGCTGGGTGTCTTGCCTGGGGCTGCCCTTTGG AAGCGGCCACACTGGATAAGAAAATCAAACTCCCCACCAATGGACAAGCAGAAAATATGCCAGATGGGGT GCAGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGTCCGAGGCGGGTGGATCACTTGAGGCCAGGAGT TCGAGACCAGCCTTGGTGAAACCCCCTGTCTACTAAAAGTACAAAATTCAGCCTGGTGCGGTGGTGTGCG CCTGTAATCCCAACACGAGAATTGCTTGAACCCAGGAGGCGGAGGTTGCAATGAGCCGAGATCGCATCAC TGCACTCCAGCCTGGGCGACAGAGCAAGACTCTGTCTCAAAAAAAAAAAAAAAAAGAAAGAAAGAAAGAA AGAAAGAAAAAAGAAAATAGTAACCTGTAGTCCCAGCCATTCCCAAGGCTTAGGTGAGAGGATTGCTTGA GCCTCGAGACCAGCCTGGGTAACAACAACGAGACACCATCTCAAAAAAAAAGAAAAAAAGAAAAGAAAGA ACAAAAAATCCCCCAAAAGCCAGAATAGAGGGTAAGGGGAGGGTAGAAGGTGGAGGGAATGGAACCACAG AGTTAGAATATTAGTCTTGGCCAGGCGCAGTGGCTCACATCTATAATCCCAGCCCTTTGGGAGGCTGAGG CAGGAGGATCACTTGTACCCAGGAGTTCAAGACCAGCCTGGGCAACATAGTGAATCCTGTCTTTACAAAA AATAAATTAGCTGGGCATGGTGGTGTATACCTGTGGTTCCAGCTACTTGGGAGGCTGAGGTGGAAGGATT GCTAGAGCCCAGGAGGTTGAGGCTGAAGTCAGCCATGATGGTATCACTTCACTACTGCCTGGGCAACAGG GCAAGATCCCATCTAAAAAAAAATTGATGTATATTTTACATACACTAAAATATACACATGCAGCTCAGCT CGATGAATTTTTATGGGTATAGACCCATGTAACCACTAGATGAAGGTAAAGAATATTTCTTAGCCCCAGC AGGCTCCTTCATGCCTCTTCGTCTTCCCAATCACTACCGCCAAGTGGTACCCACTATCCTGACTTCTCAG TGCTAGTTTAGCCTGTTCTGAAAAGTCATACAAATGGGATCATGCAGTTTGTACTGCTTTGTGTCTGGCT TCTATGGCTCAGCATGATGTTTTTGAGATGGATCTGTGTAGGGGTAGTTTGCTCTTTTTCTTTGCTGTGT GGTATGGTATTCCATCATATGAATGTCCTGTGGATTTTCTTTTCTTTTTTTCTCTTTCTTTCTTTTTCTT TCTTTTCTTTCTTTTTCTCTCTGTCCTTTCTTCTTTCTTTTCTTTCTCTTTCTCTCTCTTTATCTCCTTC CTTCCTTCCTTCCCTCCCTCCCTCTCTCTTTCCCTTTCTTTCCCTTTTTTTCTTTCTTTTCTTTTTTGTT TTGACAGAGTCTTACTCTGTCCTTTAGGGTGGGGTGCAGTGGCATGATCATAGCTCACTGTAGCCTCCAA CTCCTGGCTCAAGCTATCCTTCTGCCTCAGCCTCCTAAGTAGCTGGAACTACAGACATGTGCCACCATGT CCAGCTAATTTTTAAATTTTTTTGTAGAGACAGGGTCTTGCTTTGTTTTCCAGGCTGGTCTTGAACTCCT AGCCTCAAGTGATCCTCCCACCTTGGCCTCCCAAGGTGCTGAAATTACAGGCTTGAGCCACTGTGCCTGT TTTTTTTTTTGTTTGTTTTTGAGACGGAGTCTCACTCACTCTGTTGCCCAGGCTGGAGTGCAGTGGCGTG ATCTCAGCTCACTGCAACCTCCGCCTACTGGGTTCAACTGATTCTCTTGCTTCAGCCTCCCAGGTAGCTG GGATTTCAGATGTGCACCAACACACCTGGCTAATTTTTGTACTTTTAGTAGAGACAGAGTTTCACCACAT TGGCCAGGCTGGTCTCAAACTCCTGACCTCAAGTGATCCACCTGCCTTGGCCTCCCAGAGTGCTGGGATT ACAGGCGCCAGCCACCATGCCCAGCCATGTTCTGTTTCTTAATCTGGGTGCTGGTTACATGGGTGTGTGT GTGTGTGTGTGTGAAAATTCAGTGAGCTGCTTACTTATGACTTGTGCACATTTCCATATGTACAGTATAC TTCAAGAAAAAAAAATTTCATCAAGGAATCAAACCCAAGGAAGGACCTTAGAATCTAGCAAAGAGCCAAA ATTGGGAAGTCCTGAGGAAGCCCTTTGTCCCATCCTCACTTGACAGAGTGAACAAGAAGTAAAGCAGTTC CCTTCTGGACTGGGATGAAGGTTTAGGAGACAGATCCCCACCCGCAGCCAGGACAGTGAGGGGAGGAGGT GCAGATGTGTCTGAGAGCCAGGGCAGGCTTCCTGGTGGAGGTGACTGATGCCCTGACCCTGTTCCTTTCC CCAATCCAAACAGGCTGAATGAGAACATGTCCGTGTGTGTGGCGGACTTCGGGCTCTCCAAGAAGATCTA CAATGGGGACTACTACCGCCAGGGACGTATCGCCAAGATGCCAGTCAAGTGGATTGCCATTGAGAGTCTA GCTGACCGTGTCTACACCAGCAAGAGCGATGTGGTAGGTGCACTCCCGCCAAGAGTGGGGAACCATGGGA GGGCATGGCCTGACCATCACACACTATGCCTGGGTGGCTGTGGATGCAAGGGTCACAGGGACATGTGGGC TTCCCTTTGCAGGGGCTTGTCCACATGGGCTGGGCATGTCTTGGGGTATGGTGGGCATCTCTGAATAGTG GTGTGTACATGCCCAGGATAAATACAGGCCCACGTGTGCATGGTAGCAATGTAGACAGTTTAGGTTAGAA GAAGCTGCAGTGATTATGCGTGCATGTGCGCACACTCATAGAATGTGGACAGCCAGGGTGTGCAGAGTGG CACATGAGCTCATGTGTCCATGAAGTGTGTATATGTGTGTGATGGTGAGCATGTGTATGCATCCACAAAA GTTACTTATTCATGTGTATACCCGTGTCAAGTATTTTTTATATATATATATTTTTCTTTTTTTGAGATGG AGTCTCGCACTGTCACCCAGGCTGCAGTGCAATGGCATGATCTCAGCTCACTGCAGACTCTGCCTCCCGG GTTCAAGCAATTCTCCTGCCTCAGTCTCCCGAGTAGCTGGGATTACAGGCGCCCACCACCATGCCTAGCT AATTTTTGTATTTTTAGTAGAGACGGGGTTTCACTATATTGGCCAGGCTGGTCTCAAACTCCTGACCTCA GGCAGTCCGCCCACCTCAGCCTCCCAAAGTGCTGGGATTACAGGCATCAGCCACCGCACCCGGCTAAAGT ATTATGTTTCTATGAATACTTGTGATGCTCCCAGAGGATGGTTGTGAACATGTGTACATAAGTGTGGGTG TACCCATGAACCTGGGTATTGGTGCGGGTGATTCTGTGCAGGAGAGACTGTCTAATTCCCTCTGCCCCTC ACAGTGGTCCTTCGGGGTGACAATGTGGGAGATTGCCACAAGAGGCCAAACCCCATATCCGGGCGTGGAG AACAGCGAGATTTATGACTATCTGCGCCAGGGAAATCGCCTGAAGCAGCCTGCGGACTGTCTGGATGGAC TGTGAGGACCCTTAGGTCTCCCCCAACCCAGAATTCATTCCAAACCCCTGACTACCCCCAGATGGCCCTC ACAGGTCCAGGACTCTCTATAACCCAGACAGAATCCCTGAGAATGCTGAGTGACCCACTTGCCCCTCACC AATGCTCTGAGTAGGGCCATCACTAACCAGTGGGGTGCAAATCAGCTAAAGGCACCCTTTCCTCCTTTGT CTGTGTGGGCTGAATCAGCCCCCTGGCTCCCCACCCCCAAGCCAGGTATCCTTGGGTAGTGAATAACAGC ACAGTCTTACCTGGCGGCCCTGCCTTTGGGACATGCACTCCCAGAGACTTCTCATTCCAGACTCCTGAGC ACACCATGCTTCCCCGACATGCTCCTCAACACCTGAGACTCTCTGCAAAACCCTTCAGTTTGTTTTATTG GCCTTCTCCAGACTCAGGTCTCCTCTGAGATATTTGCAGGATCCTTCAGGGAATGCTTACCAAACTTTGC AATATTGGAGTATGCGGAGAAGGCCGTGACATTTAGCTAGCACTTTGAGGGTAAAGAGAGGATGACTTTG GGTCAGGAGGAGACAGCCTGGGGCGTCAGACTCCTCAGTCCACCTTGGGTACTCCAAGAGCTGAGACGAG TAAAAATAACAGCTAACATTTTCATATAACTGACTAGAAGGCACTGTTTTAGGTGCCTGGCATGTGTCAA ATCATTTGGTCCTTACCACAGCCATGTGATGTAGATAGGTATCATTATGATTCCCATTCTGCAGATAAGA AAACCCAGTCCTACAGGGAGGGTAATTTATTTTTATTTATTGACTTGAGTCTCGCTCTGTCGCCCAGGCT GGAGCACAATGGCTCCATCTCGGCTCACTGCAACCTCCCAGGTTCTAGCGATTCTCTTGCCTCAGCCTCC CAAGTAGCTGGGACTACAGGCGTGTGCCACCATGCCCAGCTAATTTTTTTTGTATTTTTAGTAGAGATGG GGTTTCACCACCTTAGCCAGGATGGTCTTGATATCGTGACCTCATGATCCACCCGTCCCAGCCTCCCAAA GTGCTGGGATTATAGGCATGAGCCTCCACGCCCAGTCTGGGAGGGTGATTTATTTGCCAAAGATTGCACA GCTGGTGTGTTTGTTATCTATATCCCCAAATCAAGTAGTTTAAAACAACAAACGTTTATTATCTCACACA ATTTCTGAAAGTTGGATACTGGGAACAGCTTAGCAGGGTGATTTTGGTTCAGGATCTCTAATGAAGTTAC AAAGATATCACTGGGGGCTGCAGTCATCTGAAGGTTGGGACTGGAGGATTGCTTTCAAGGTGGCTTACTC ACATGGCTGTAGCAGGAGGCTTCAGTTCGTTGCCATGTGGACCCCTTTGTGGCACTGCTTGAGCTTACTC ACAACATGGCAACCCAGGAGAAAGTGCGAGGAAGCCACATGCCTTTTATGACCTAGTCTCAGAAGTCACA CACACCATCACTTCTGCCAAATCAGAAGCAAGTCACTAAGTCCTGCCCATGCTCAAGAGGAGAGGATTTA TTCTCCGTCTTTTGCAGGGAGGAGGGTCAAAGAATTTATGGACCTATTTTAAACCAGCACAGCTTGTAAG TGGCATAGCCAGGCTTTGATGCAAGTCTGTTCTGGGGAGCTGGAAGGTCTGTTCTAGCAAACCCTCATCA GAATACTACTCCATATACAGACAGGTTTCCCGAGACCCTTCCCAGCTCCTGAGTCTCCCAGGACCCAACT CAGAAATTCTTGGGAATTCCCAAATCCCCATAGATGGCCTCAAACTGCTGAGGCTCCCTATAACCCTCTA AAATGCCCCCAGTCCCCTGAGTGTCCTAAAATGTCCCCAGGCTTCCAGAATGCACCCCTTCTGAGTCCCT GCTCAATCTCCCACCCCTCATTTTGCTGCCCTAGGTATGCCTTGATGTCGCGGTGCTGGGAGCTAAATCC CCAGGACCGGCCAAGTTTTACAGAGCTGCGGGAAGATTTGGAGAACACACTGAAGGCCTTGCCTCCTGCC CAGGAGCCTGACGAAATCCTCTATGTCAACATGGATGAGGGTGGAGGTTATCCTGAACCCCCTGGAGCTG CAGGAGGAGCTGACCCCCCAACCCAGCCAGACCCTAAGGATTCCTGTAGCTGCCTCACTGCGGCTGAGGT CCATCCTGCTGGACGCTATGTCCTCTGCCCTTCCACAACCCCTAGCCCCGCTCAGCCTGCTGATAGGGGC TCCCCAGCAGCCCCAGGGCAGGAGGATGGTGCCTGAGACAACCCTCCACCTGGTACTCCCTCTCAGGATC CAAGCTAAGCACTGCCACTGGGGAAAACTCCACCTTCCCACTTTCCCACCCCACGCCTTATCCCCACTTG CAGCCCTGTCTTCCTACCTATCCCACCTCCATCCCAGACAGGTCCCTCCCCTTCTCTGTGCAGTAGCATC ACCTTGAAAGCAGTAGCATCACCATCTGTAAAAGGAAGGGGTTGGATTGCAATATCTGAAGCCCTCCCAG GTGTTAACATTCCAAGACTCTAGAGTCCAAGGTTTAAAGAGTCTAGATTCAAAGGTTCTAGGTTTCAAAG ATGCTGTGAGTCTTTGGTTCTAAGGACCTGAAATTCCAAAGTCTCTAATTCTATTAAAGTGCTAAGGTTC TAAGGCCTACTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTGCGATAGAGTCTCACTGTGTCACCCAGGC TGGAGTGCAGTGGTGCAATCTCGCCTCACTGCAACCTTCACCTACCGAGTTCAAGTGATTTTCCTGCCTT GGCCTCCCAAGTAGCTGGGATTACAGGTGTGTGCCACCACACCCGGCTAATTTTTATATTTTTAGTAGAG ACAGGGTTTCACCATGTTGGCCAGGCTGGTCTAAAACTCCTGACCTCAAGTGATCTGCCCACCTCAGCCT CCCAAAGTGCTGAGATTACAGGCATGAGCCACTGCACTCAACCTTAAGACCTACTGTTCTAAAGCTCTGA CATTATGTGGTTTTAGATTTTCTGGTTCTAACATTTTTGATAAAGCCTCAAGGTTTTAGGTTCTAAAGTT CTAAGATTCTGATTTTAGGAGCTAAGGCTCTATGAGTCTAGATGTTTATTCTTCTAGAGTTCAGAGTCCT TAAAATGTAAGATTATAGATTCTAAAGATTCTATAGTTCTAGACATGGAGGTTCTAAGGCCTAGGATTCT AAAATGTGATGTTCTAAGGCTCTGAGAGTCTAGATTCTCTGGCTGTAAGGCTCTAGATCATAAGGCTTCA AAATGTTATCTTCTCAAGTTCTAAGATTCTAATGATGATCAATTATAGTTTCTGAGGCTTTATGATAATA GATTCTCTTGTATAAGATCCTAGATCCTAAGGGTCGAAAGCTCTAGAATCTGCAATTCAAAAGTTCCAAG AGTCTAAAGATGGAGTTTCTAAGGTCCGGTGTTCTAAGATGTGATATTCTAAGACTTACTCTAAGATCTT AGATTCTCTGTGTCTAAGATTCTAGATCAGATGCTCCAAGATTCTAGATGATTAAATAAGATTCTAACGG TCTGTTCTGTTTCAAGGCACTCTAGATTCCATTGGTCCAAGATTCCGGATCCTAAGCATCTAAGTTATAA GACTCTCACACTCAGTTGTGACTAACTAGACACCAAAGTTCTAATAATTTCTAATGTTGGACACCTTTAG GTTCTTTGCTGCATTCTGCCTCTCTAGGACCATGGTTAAGAGTCCAAGAATCCACATTTCTAAAATCTTA TAGTTCTAGGCACTGTAGTTCTAAGACTCAAATGTTCTAAGTTTCTAAGATTCTAAAGGTCCACAGGTCT AGACTATTAGGTGCAATTTCAAGGTTCTAACCCTATACTGTAGTATTCTTTGGGGTGCCCCTCTCCTTCT TAGCTATCATTGCTTCCTCCTCCCCAACTGTGGGGGTGTGCCCCCTTCAAGCCTGTGCAATGCATTAGGG ATGCCTCCTTTCCCGCAGGGGATGGACGATCTCCCACCTTTCGGGCCATGTTGCCCCCGTGAGCCAATCC CTCACCTTCTGAGTACAGAGTGTGGACTCTGGTGCCTCCAGAGGGGCTCAGGTCACATAAAACTTTGTAT ATCAACGAG Download Select all
Length	42569
OMIM ID	109135
HGNC ID	HGNC:905
Unigene ID	Hs.590970
Ensembl ID	ENSG00000167601
PharmGKB ID	-

mRNA Information

mRNA ID	NM_021913.4
Exon	join(1..279,1438..1660,1948..2048,2682..2858,11769..11849, 11985..12100,18746..18956,19272..19411,19966..20116, 20496..20522,23685..23817,24418..24509,29316..29411, 29545..29622,33153..33245,33648..33769,34401..34510, 37254..37413,38295..38431,40355..42569)
mRNA Sequence	>558 AGCACACGCGTAAACAACACGCAGAACTGCAGTCGCACTTACAAGACTTGGTCCCAGGGCCGGG CACCGAGTGGCTCTGCCTGCGATCCAGCACTTTGGGAGGCCGAGGCGGGAGGATCGCTTGGGGC CAGAAGTTTGAGAGCAGCCTGGGCAACGTGGGCTGAACAAGACATCCTCTTTCTCCTGCGAAGC CCATAACGCCAAGGGGGTCACCACATCCCGCACAGCCACCATCACAGTGCTCCCCCAGCAGCCC CGTAACCTCCACCTGGTCTCCCGCCAACCCACGGAGCTGGAGGTGGCTTGGACTCCAGGCCTGA GCGGCATCTACCCCCTGACCCACTGCACCCTGCAGGCTGTGCTGTCAGACGATGGGATGGGCAT CCAGGCGGGAGAACCAGACCCCCCAGAGGAGCCCCTCACCTCGCAAGCATCCGTGCCCCCCCAT CAGCTTCGGCTAGGCAGCCTCCATCCTCACACCCCTTATCACATCCGCGTGGCATGCACCAGCA GCCAGGGCCCCTCATCCTGGACCCACTGGCTTCCTGTGGAGACGCCGGAGGGAGTGCCCCTGGG CCCCCCTGAGAACATTAGTGCTACGCGGAATGGGAGCCAGGCCTTCGTGCATTGGCAAGAGCCC CGGGCGCCCCTGCAGGGTACCCTGTTAGGGTACCGGCTGGCGTATCAAGGCCAGGACACCCCAG AGGTGCTAATGGACATAGGGCTAAGGCAAGAGGTGACCCTGGAGCTGCAGGGGGACGGGTCTGT GTCCAATCTGACAGTGTGTGTGGCAGCCTACACTGCTGCTGGGGATGGACCCTGGAGCCTCCCA GTACCCCTGGAGGCCTGGCGCCCAGGGCAAGCACAGCCAGTCCACCAGCTGGTGAAGGAACCTT CAACTCCTGCCTTCTCGTGGCCCTGGTGGTATGTACTGCTAGGAGCAGTCGTGGCCGCTGCCTG TGTCCTCATCTTGGCTCTCTTCCTTGTCCACCGGCGAAAGAAGGAGACCCGTTATGGAGAAGTG TTTGAACCAACAGTGGAAAGAGGTGAACTGGTAGTCAGGTACCGCGTGCGCAAGTCCTACAGTC GTCGGACCACTGAAGCTACCTTGAACAGCCTGGGCATCAGTGAAGAGCTGAAGGAGAAGCTGCG GGATGTGATGGTGGACCGGCACAAGGTGGCCCTGGGGAAGACTCTGGGAGAGGGAGAGTTTGGA GCTGTGATGGAAGGCCAGCTCAACCAGGACGACTCCATCCTCAAGGTGGCTGTGAAGACGATGA AGATTGCCATCTGCACGAGGTCAGAGCTGGAGGATTTCCTGAGTGAAGCGGTCTGCATGAAGGA ATTTGACCATCCCAACGTCATGAGGCTCATCGGTGTCTGTTTCCAGGGTTCTGAACGAGAGAGC TTCCCAGCACCTGTGGTCATCTTACCTTTCATGAAACATGGAGACCTACACAGCTTCCTCCTCT ATTCCCGGCTCGGGGACCAGCCAGTGTACCTGCCCACTCAGATGCTAGTGAAGTTCATGGCAGA CATCGCCAGTGGCATGGAGTATCTGAGTACCAAGAGATTCATACACCGGGACCTGGCGGCCAGG AACTGCATGCTGAATGAGAACATGTCCGTGTGTGTGGCGGACTTCGGGCTCTCCAAGAAGATCT ACAATGGGGACTACTACCGCCAGGGACGTATCGCCAAGATGCCAGTCAAGTGGATTGCCATTGA GAGTCTAGCTGACCGTGTCTACACCAGCAAGAGCGATGTGTGGTCCTTCGGGGTGACAATGTGG GAGATTGCCACAAGAGGCCAAACCCCATATCCGGGCGTGGAGAACAGCGAGATTTATGACTATC TGCGCCAGGGAAATCGCCTGAAGCAGCCTGCGGACTGTCTGGATGGACTGTATGCCTTGATGTC GCGGTGCTGGGAGCTAAATCCCCAGGACCGGCCAAGTTTTACAGAGCTGCGGGAAGATTTGGAG AACACACTGAAGGCCTTGCCTCCTGCCCAGGAGCCTGACGAAATCCTCTATGTCAACATGGATG AGGGTGGAGGTTATCCTGAACCCCCTGGAGCTGCAGGAGGAGCTGACCCCCCAACCCAGCCAGA CCCTAAGGATTCCTGTAGCTGCCTCACTGCGGCTGAGGTCCATCCTGCTGGACGCTATGTCCTC TGCCCTTCCACAACCCCTAGCCCCGCTCAGCCTGCTGATAGGGGCTCCCCAGCAGCCCCAGGGC AGGAGGATGGTGCCTGAGACAACCCTCCACCTGGTACTCCCTCTCAGGATCCAAGCTAAGCACT GCCACTGGGGAAAACTCCACCTTCCCACTTTCCCACCCCACGCCTTATCCCCACTTGCAGCCCT GTCTTCCTACCTATCCCACCTCCATCCCAGACAGGTCCCTCCCCTTCTCTGTGCAGTAGCATCA CCTTGAAAGCAGTAGCATCACCATCTGTAAAAGGAAGGGGTTGGATTGCAATATCTGAAGCCCT CCCAGGTGTTAACATTCCAAGACTCTAGAGTCCAAGGTTTAAAGAGTCTAGATTCAAAGGTTCT AGGTTTCAAAGATGCTGTGAGTCTTTGGTTCTAAGGACCTGAAATTCCAAAGTCTCTAATTCTA TTAAAGTGCTAAGGTTCTAAGGCCTACTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTGCGATA GAGTCTCACTGTGTCACCCAGGCTGGAGTGCAGTGGTGCAATCTCGCCTCACTGCAACCTTCAC CTACCGAGTTCAAGTGATTTTCCTGCCTTGGCCTCCCAAGTAGCTGGGATTACAGGTGTGTGCC ACCACACCCGGCTAATTTTTATATTTTTAGTAGAGACAGGGTTTCACCATGTTGGCCAGGCTGG TCTAAAACTCCTGACCTCAAGTGATCTGCCCACCTCAGCCTCCCAAAGTGCTGAGATTACAGGC ATGAGCCACTGCACTCAACCTTAAGACCTACTGTTCTAAAGCTCTGACATTATGTGGTTTTAGA TTTTCTGGTTCTAACATTTTTGATAAAGCCTCAAGGTTTTAGGTTCTAAAGTTCTAAGATTCTG ATTTTAGGAGCTAAGGCTCTATGAGTCTAGATGTTTATTCTTCTAGAGTTCAGAGTCCTTAAAA TGTAAGATTATAGATTCTAAAGATTCTATAGTTCTAGACATGGAGGTTCTAAGGCCTAGGATTC TAAAATGTGATGTTCTAAGGCTCTGAGAGTCTAGATTCTCTGGCTGTAAGGCTCTAGATCATAA GGCTTCAAAATGTTATCTTCTCAAGTTCTAAGATTCTAATGATGATCAATTATAGTTTCTGAGG CTTTATGATAATAGATTCTCTTGTATAAGATCCTAGATCCTAAGGGTCGAAAGCTCTAGAATCT GCAATTCAAAAGTTCCAAGAGTCTAAAGATGGAGTTTCTAAGGTCCGGTGTTCTAAGATGTGAT ATTCTAAGACTTACTCTAAGATCTTAGATTCTCTGTGTCTAAGATTCTAGATCAGATGCTCCAA GATTCTAGATGATTAAATAAGATTCTAACGGTCTGTTCTGTTTCAAGGCACTCTAGATTCCATT GGTCCAAGATTCCGGATCCTAAGCATCTAAGTTATAAGACTCTCACACTCAGTTGTGACTAACT AGACACCAAAGTTCTAATAATTTCTAATGTTGGACACCTTTAGGTTCTTTGCTGCATTCTGCCT CTCTAGGACCATGGTTAAGAGTCCAAGAATCCACATTTCTAAAATCTTATAGTTCTAGGCACTG TAGTTCTAAGACTCAAATGTTCTAAGTTTCTAAGATTCTAAAGGTCCACAGGTCTAGACTATTA GGTGCAATTTCAAGGTTCTAACCCTATACTGTAGTATTCTTTGGGGTGCCCCTCTCCTTCTTAG CTATCATTGCTTCCTCCTCCCCAACTGTGGGGGTGTGCCCCCTTCAAGCCTGTGCAATGCATTA GGGATGCCTCCTTTCCCGCAGGGGATGGACGATCTCCCACCTTTCGGGCCATGTTGCCCCCGTG AGCCAATCCCTCACCTTCTGAGTACAGAGTGTGGACTCTGGTGCCTCCAGAGGGGCTCAGGTCA CATAAAACTTTGTATATCAACGAGAAAAAAAA Download Select all
Length	4128

CDS Information

Location	join(195..279,1438..1660,1948..2048,2682..2858, 11769..11849,11985..12100,18746..18956,19272..19411, 19966..20116,20496..20522,23685..23817,24418..24509, 29316..29411,29545..29622,33153..33245,33648..33769, 34401..34510,37254..37413,38295..38431,40355..40706)
CDS Sequence	>lcl\|NM_001278599.1_cds_NP_001265528.1_1 [gene=AXL] [protein=tyrosine-protein kinase receptor UFO isoform 3] [protein_id=NP_001265528.1] [location=377..2257] ATGGGCATCCAGGCGGGAGAACCAGACCCCCCAGAGGAGCCCCTCACCTCGCAAGCATCCGTGCCCCCCC ATCAGCTTCGGCTAGGCAGCCTCCATCCTCACACCCCTTATCACATCCGCGTGGCATGCACCAGCAGCCA GGGCCCCTCATCCTGGACCCACTGGCTTCCTGTGGAGACGCCGGAGGGAGTGCCCCTGGGCCCCCCTGAG AACATTAGTGCTACGCGGAATGGGAGCCAGGCCTTCGTGCATTGGCAAGAGCCCCGGGCGCCCCTGCAGG GTACCCTGTTAGGGTACCGGCTGGCGTATCAAGGCCAGGACACCCCAGAGGTGCTAATGGACATAGGGCT AAGGCAAGAGGTGACCCTGGAGCTGCAGGGGGACGGGTCTGTGTCCAATCTGACAGTGTGTGTGGCAGCC TACACTGCTGCTGGGGATGGACCCTGGAGCCTCCCAGTACCCCTGGAGGCCTGGCGCCCAGGGCAAGCAC AGCCAGTCCACCAGCTGGTGAAGGAACCTTCAACTCCTGCCTTCTCGTGGCCCTGGTGGTATGTACTGCT AGGAGCAGTCGTGGCCGCTGCCTGTGTCCTCATCTTGGCTCTCTTCCTTGTCCACCGGCGAAAGAAGGAG ACCCGTTATGGAGAAGTGTTTGAACCAACAGTGGAAAGAGGTGAACTGGTAGTCAGGTACCGCGTGCGCA AGTCCTACAGTCGTCGGACCACTGAAGCTACCTTGAACAGCCTGGGCATCAGTGAAGAGCTGAAGGAGAA GCTGCGGGATGTGATGGTGGACCGGCACAAGGTGGCCCTGGGGAAGACTCTGGGAGAGGGAGAGTTTGGA GCTGTGATGGAAGGCCAGCTCAACCAGGACGACTCCATCCTCAAGGTGGCTGTGAAGACGATGAAGATTG CCATCTGCACGAGGTCAGAGCTGGAGGATTTCCTGAGTGAAGCGGTCTGCATGAAGGAATTTGACCATCC CAACGTCATGAGGCTCATCGGTGTCTGTTTCCAGGGTTCTGAACGAGAGAGCTTCCCAGCACCTGTGGTC ATCTTACCTTTCATGAAACATGGAGACCTACACAGCTTCCTCCTCTATTCCCGGCTCGGGGACCAGCCAG TGTACCTGCCCACTCAGATGCTAGTGAAGTTCATGGCAGACATCGCCAGTGGCATGGAGTATCTGAGTAC CAAGAGATTCATACACCGGGACCTGGCGGCCAGGAACTGCATGCTGAATGAGAACATGTCCGTGTGTGTG GCGGACTTCGGGCTCTCCAAGAAGATCTACAATGGGGACTACTACCGCCAGGGACGTATCGCCAAGATGC CAGTCAAGTGGATTGCCATTGAGAGTCTAGCTGACCGTGTCTACACCAGCAAGAGCGATGTGTGGTCCTT CGGGGTGACAATGTGGGAGATTGCCACAAGAGGCCAAACCCCATATCCGGGCGTGGAGAACAGCGAGATT TATGACTATCTGCGCCAGGGAAATCGCCTGAAGCAGCCTGCGGACTGTCTGGATGGACTGTATGCCTTGA TGTCGCGGTGCTGGGAGCTAAATCCCCAGGACCGGCCAAGTTTTACAGAGCTGCGGGAAGATTTGGAGAA CACACTGAAGGCCTTGCCTCCTGCCCAGGAGCCTGACGAAATCCTCTATGTCAACATGGATGAGGGTGGA GGTTATCCTGAACCCCCTGGAGCTGCAGGAGGAGCTGACCCCCCAACCCAGCCAGACCCTAAGGATTCCT GTAGCTGCCTCACTGCGGCTGAGGTCCATCCTGCTGGACGCTATGTCCTCTGCCCTTCCACAACCCCTAG CCCCGCTCAGCCTGCTGATAGGGGCTCCCCAGCAGCCCCAGGGCAGGAGGATGGTGCCTGA Download Select all
CCDS ID	CCDS12575.1

Protein Information

Protein ID	NP_001690.2
Protein Name	AXL receptor tyrosine kinase
Molecular Wt. (Da)	93832
Protein Sequence	>558 MAWRCPRMGRVPLAWCLALCGWACMAPRGTQAEESPFVGNPGNITGARGLTGTLRCQLQVQGEP PEVHWLRDGQILELADSTQTQVPLGEDEQDDWIVVSQLRITSLQLSDTGQYQCLVFLGHQTFVS QPGYVGLEGLPYFLEEPEDRTVAANTPFNLSCQAQGPPEPVDLLWLQDAVPLATAPGHGPQRSL HVPGLNKTSSFSCEAHNAKGVTTSRTATITVLPQQPRNLHLVSRQPTELEVAWTPGLSGIYPLT HCTLQAVLSDDGMGIQAGEPDPPEEPLTSQASVPPHQLRLGSLHPHTPYHIRVACTSSQGPSSW THWLPVETPEGVPLGPPENISATRNGSQAFVHWQEPRAPLQGTLLGYRLAYQGQDTPEVLMDIG LRQEVTLELQGDGSVSNLTVCVAAYTAAGDGPWSLPVPLEAWRPVKEPSTPAFSWPWWYVLLGA VVAAACVLILALFLVHRRKKETRYGEVFEPTVERGELVVRYRVRKSYSRRTTEATLNSLGISEE LKEKLRDVMVDRHKVALGKTLGEGEFGAVMEGQLNQDDSILKVAVKTMKIAICTRSELEDFLSE AVCMKEFDHPNVMRLIGVCFQGSERESFPAPVVILPFMKHGDLHSFLLYSRLGDQPVYLPTQML VKFMADIASGMEYLSTKRFIHRDLAARNCMLNENMSVCVADFGLSKKIYNGDYYRQGRIAKMPV KWIAIESLADRVYTSKSDVWSFGVTMWEIATRGQTPYPGVENSEIYDYLRQGNRLKQPADCLDG LYALMSRCWELNPQDRPSFTELREDLENTLKALPPAQEPDEILYVNMDEGGGYPEPPGAAGGAD PPTQPDPKDSCSCLTAAEVHPAGRYVLCPSTTPSPAQPADRGSPAAPGQEDGA Download Select all
Length	885
Uniprot ID	P29033
Ensembl Protein ID	ENSP00000372295

Post-translational Modification Information (Source : HPRD)

Residue	Type	site
Y	Phosphorylation	770
Y	Phosphorylation	812
Y	Phosphorylation	857
Y	Phosphorylation	779
Y	Phosphorylation	821
Y	Phosphorylation	866
S	Phosphorylation	884
S	Phosphorylation	875
S	Phosphorylation	875
S	Phosphorylation	866
Y	Phosphorylation	702
Y	Phosphorylation	693
Y	Phosphorylation	481
Y	Phosphorylation	472

Enzyme Information

EC	2.7.10.1
Name	receptor protein-tyrosine kinase AATK AATYK AATYK2 AATYK3 ACH ALK anaplastic lymphoma kinase ARK ATP:protein-tyrosine O-phosphotransferase (ambiguous) AXL Bek Bfgfr BRT Bsk C-FMS CAK CCK4 CD115 CD135 CDw135 Cek1 Cek10 Cek11 Cek2 Cek3 Cek5 Cek6 Cek7 CFD1 CKIT CSF1R DAlk DDR1 DDR2 Dek DKFZp434C1418 Drosophila Eph kinase DRT DTK Ebk ECK EDDR1 Eek EGFR Ehk2 Ehk3 Elk EPH EPHA1 EPHA2 EPHA6 EPHA7 EPHA8 EPHB1 EPHB2 EPHB3 EPHB4 EphB5 ephrin-B3 receptor tyrosine kinase EPHT EPHT2 EPHT3 EPHX ERBB ERBB1 ERBB2 ERBB3 ERBB4 ERK Eyk FGFR1 FGFR2 FGFR3 FGFR4 FLG FLK1 FLK2 FLT1 FLT2 FLT3 FLT4 FMS Fv2 HBGFR HEK11 HEK2 HEK3 HEK5 HEK6 HEP HER2 HER3 HER4 HGFR HSCR1 HTK IGF1R INSR INSRR insulin receptor protein-tyrosine kinase IR IRR JTK12 JTK13 JTK14 JWS K-SAM KDR KGFR KIA0641 KIAA1079 KIAA1459 Kil Kin15 Kin16 KIT KLG LTK MCF3 Mdk1 Mdk2 Mdk5 MEhk1 MEN2A/B Mep MER MERTK MET Mlk1 Mlk2 Mrk MST1R MTC1 MUSK Myk1 N-SAM NEP NET Neu neurite outgrowth regulating kinase NGL NOK nork novel oncogene with kinase-domain Nsk2 NTRK1 NTRK2 NTRK3 NTRK4 NTRKR1 NTRKR2 NTRKR3 Nuk NYK PCL PDGFR PDGFRA PDGFRB PHB6 protein-tyrosine kinase (ambiguous) protein tyrosine kinase (ambiguous) PTK PTK3 PTK7 receptor protein tyrosine kinase RET RON ROR1 ROR2 ROS1 RSE RTK RYK SEA Sek2 Sek3 Sek4 Sfr SKY STK STK1 TEK TIE TIE1 TIE2 TIF TKT TRK TRKA TRKB TRKC TRKE TYK1 TYRO10 Tyro11 TYRO3 Tyro5 Tyro6 TYRO7 UFO VEGFR1 VEGFR2 VEGFR3 Vik YK1 Yrk
Class	Transferases; Transferring phosphorus-containing groups; Protein-tyrosine kinases
Sysname	ATP:[protein]-L-tyrosine O-phosphotransferase (receptor-type)
Substrate	ATP [CPD:C00002]; [protein]-L-tyrosine
Product	ADP [CPD:C00008]; [protein]-L-tyrosine phosphate
Reaction (IUBMB)

PPi Information

(Click to view network : Source STRING) View

Interactant Gene ID (Source: HPRD)	Gene Symbol	HPRD ID	Ref Seq ID	Technique	References
102	ADAM10	3723	NP_001101.1	in vivo	162 275 847 822 279
867	CBL	1320	NP_005179.2	in vivo	15958209
2885	GRB2	150	NP_002077.1	in vitro;in vivo	9178760
3561	IL2RG	2391	NP_000197.1	in vivo	16308569
3601	IL15RA	3045	NP_002180.1	in vitro;in vivo	16308569
5295	PIK3R1	1381	NP_852664.1	in vitro;in vivo	9178760
5335	PLCG1	1398	NP_002651.2	in vitro;in vivo	9178760
5781	PTPN11	1470	NP_002825.3	in vivo	15507525
6464	SHC1	2780	NP_001123512.1	in vitro	8610109
8440	NCK2	5378	NP_003572.2	yeast 2-hybrid	12470648
8503	PIK3R3	5831	NP_003620.3	yeast 2-hybrid	12470648
8651	SOCS1	4669	NP_003736.1	yeast 2-hybrid	12470648
10048	RANBP9	4835	NP_005484.2	yeast 2-hybrid	12470648
53358	SHC3	12005	NP_058544.3	in vivo	8610109

Pathway Information

No matching records could be found.

Structure Information

PDB ID	2C5D
Resolution	3.3
Method	X-RAY DIFFRACTION
Chains	C, D
Molecule	TYROSINE-PROTEIN KINASE RECEPTOR UFO
Model	View

Domain Information

ID	Location	Description
cd05075	535-811	PTKc_Axl
cl21453	535-811	PKc_like superfamily
cd05749	141-222	Ig2_Tyro3_like
cl11960	141-222	Ig superfamily
cd00063	225-328	FN3
cl21522	225-328	FN3 superfamily
cd00096	53-126	Ig
cl11960	53-126	Ig superfamily
cd00063	335-422	FN3
cl21522	335-422	FN3 superfamily
cd05035	536-807	PTKc_TAM
cd14204	528-811	PTKc_Mer
cd05074	526-805	PTKc_Tyro3
cd00192	540-804	PTKc
cd05032	531-805	PTKc_InsR_like
cd05058	542-804	PTKc_Met_Ron
cd05053	531-807	PTKc_FGFR
cd05044	540-805	PTKc_c-ros
cd05036	531-804	PTKc_ALK_LTK
cd05034	540-804	PTKc_Src_like
cd05052	531-805	PTKc_Abl
cd05061	531-815	PTKc_InsR
cd05056	531-807	PTKc_FAK
cd05045	535-807	PTKc_RET
cd05039	538-805	PTKc_Csk_like
cd05049	531-805	PTKc_Trk
cd05043	531-799	PTK_Ryk
cd05041	542-803	PTKc_Fes_like
cd05099	533-810	PTKc_FGFR4
cd05051	533-799	PTKc_DDR
cd05033	536-805	PTKc_EphR
cd05098	531-815	PTKc_FGFR1
cd05068	531-804	PTKc_Frk_like
cd05050	531-804	PTKc_Musk
cd05059	531-803	PTKc_Tec_like
cd05060	540-805	PTKc_Syk_like
cd05085	539-803	PTKc_Fer
cd05084	539-803	PTKc_Fes
cd05048	534-799	PTKc_Ror
cd05062	531-799	PTKc_IGF-1R
cd05101	533-807	PTKc_FGFR2
cd05046	540-805	PTK_CCK4
cd05040	540-803	PTKc_Ack_like
cd05054	533-805	PTKc_VEGFR
cd05047	542-808	PTKc_Tie
cd13999	542-799	STKc_MAP3K-like
cd05057	539-812	PTKc_EGFR_like
cd05089	542-824	PTKc_Tie1
cd05100	533-807	PTKc_FGFR3
cd05148	533-805	PTKc_Srm_Brk
cd05055	533-807	PTKc_PDGFR
cd05112	531-803	PTKc_Itk
cd05092	531-804	PTKc_TrkA
cd05083	530-804	PTKc_Chk
cd05038	540-804	PTKc_Jak_rpt2
cd05093	531-811	PTKc_TrkB
cd05066	531-799	PTKc_EphR_A
cd05065	531-804	PTKc_EphR_B
cd05067	531-809	PTKc_Lck_Blk
cd05095	533-804	PTKc_DDR2
cd05088	531-808	PTKc_Tie2
cd05072	531-805	PTKc_Lyn
cd05108	540-833	PTKc_EGFR
cd05097	533-803	PTKc_DDR_like
cd05063	536-807	PTKc_EphR_A2
cd05115	542-809	PTKc_Zap-70
cd05113	531-799	PTKc_Btk_Bmx
cd14207	533-805	PTKc_VEGFR1
cd05102	533-808	PTKc_VEGFR3
cd05103	533-809	PTKc_VEGFR2
cd05082	531-805	PTKc_Csk
cd05116	540-800	PTKc_Syk
cd05096	533-799	PTKc_DDR1
cd05073	531-805	PTKc_Hck
cd14203	540-805	PTKc_Src_Fyn_like
cd05114	531-803	PTKc_Tec_Rlk
cd05094	531-811	PTKc_TrkC
cd05106	533-807	PTKc_CSF-1R
cd05110	540-833	PTKc_HER4
cd05090	542-803	PTKc_Ror1
cd05109	540-803	PTKc_HER2
cd05071	531-820	PTKc_Src
cd05107	531-807	PTKc_PDGFR_beta
cd05111	539-799	PTK_HER3
cd05069	531-818	PTKc_Yes
cd00180	542-803	PKc
cd05091	542-809	PTKc_Ror2
cd05070	531-816	PTKc_Fyn
cd05105	533-807	PTKc_PDGFR_alpha
cd05064	531-807	PTKc_EphR_A10
cd14205	532-805	PTKc_Jak2_rpt2
cd05104	533-807	PTKc_Kit
cd05080	534-804	PTKc_Tyk2_rpt2
cd05081	542-804	PTKc_Jak3_rpt2
cd05087	540-799	PTKc_Aatyk1
cd05079	540-807	PTKc_Jak1_rpt2
cd14059	542-804	STKc_MAP3K12_13
cd14206	542-799	PTKc_Aatyk3
cd05042	540-799	PTKc_Aatyk
cd06606	539-802	STKc_MAPKKK
cd14058	542-811	STKc_TAK1
cd13978	542-798	STKc_RIP
cd14154	542-804	STKc_LIMK
cd14014	538-805	STKc_PknB_like
cd14066	542-805	STKc_IRAK
cd14065	567-803	PKc_LIMK_like
cd14145	531-803	STKc_MLK1
cd05086	542-799	PTKc_Aatyk2
cd14146	542-803	STKc_MLK4
cd14061	542-805	STKc_MLK
cd14221	582-810	STKc_LIMK1
cd14222	566-804	STKc_LIMK2
cd14148	542-804	STKc_MLK2
cd05122	538-799	PKc_STE
cd05123	542-801	STKc_AGC
cd14155	542-810	PKc_TESK
cd14064	542-804	PKc_TNNI3K
cd06627	538-799	STKc_Cdc7_like
cd08215	540-799	STKc_Nek
cd14008	542-802	STKc_LKB1_CaMKK
cd14062	542-804	STKc_Raf
cd14147	532-804	STKc_MLK3
cd14060	543-805	STKc_MLTK
cd13992	589-796	PK_GC
cd14003	538-802	STKc_AMPK-like
cd14151	535-810	STKc_B-Raf
cd14063	536-804	PK_KSR
cd14027	580-801	STKc_RIP1
cd06610	563-801	STKc_OSR1_SPAK
cd05117	538-795	STKc_CAMK
cd06611	542-802	STKc_SLK_like
cd14009	542-799	STKc_ATG1_ULK_like
cd06623	540-801	PKc_MAPKK_plant_like
cd14150	535-804	STKc_A-Raf
cd08529	538-799	STKc_FA2-like
cd14007	538-799	STKc_Aurora
cd05118	540-799	STKc_CMGC
cd06632	539-801	STKc_MEKK1_plant
cd14099	539-802	STKc_PLK
cd07841	539-798	STKc_CDK7
cd06641	540-799	STKc_MST3
cd08530	540-799	STKc_CNK2-like
cd14025	542-810	STKc_RIP4_like
cd14149	531-811	STKc_C-Raf
cd05037	542-803	PTK_Jak_rpt1
cd05581	539-795	STKc_PDK1
cd14056	540-795	STKc_TGFbR_I
cd14045	560-803	PK_GC_unk
cd14057	564-796	PK_ILK
cd14158	532-805	STKc_IRAK4
cd06642	542-799	STKc_STK25
cd14069	538-802	STKc_Chk1
cd06631	539-745	STKc_YSK4
cd06640	542-799	STKc_MST4
cd06614	542-799	STKc_PAK
cd06612	542-799	STKc_MST1_2
cd14156	580-804	PKc_LIMK_like_unk
cd14121	564-798	STKc_ULK3
cd13979	538-795	STKc_Mos
cd06617	541-801	PKc_MKK3_6
cd08219	540-799	STKc_Nek3
cd05076	582-801	PTK_Tyk2_rpt1
cd07829	542-795	STKc_CDK_like
cd06626	539-802	STKc_MEKK4
cd14664	542-805	STK_BAK1_like
cd06644	542-801	STKc_STK10
cd06643	542-799	STKc_SLK
cd14152	535-808	STKc_KSR1
cd06608	538-801	STKc_myosinIII_N_like
cd14026	542-808	STKc_RIP2
cd14161	533-799	STKc_NUAK2
cd08217	540-802	STKc_Nek2
cd07834	540-826	STKc_MAPK
cd05589	542-760	STKc_PKN
cd05077	582-803	PTK_Jak1_rpt1
cd14080	538-739	STKc_TSSK-like
cd14208	539-803	PTK_Jak3_rpt1
cd14116	538-801	STKc_Aurora-A
cd08224	537-799	STKc_Nek6_7
cd14072	535-802	STKc_MARK
cd14153	535-808	PK_KSR2
cd05619	538-766	STKc_nPKC_theta
cd05620	540-764	STKc_nPKC_delta
cd14220	540-803	STKc_BMPR1a
cd14199	576-800	STKc_CaMKK2
cd08225	540-799	STKc_Nek5
cd14663	535-802	STKc_SnRK3
cd07866	538-745	STKc_BUR1
cd05078	540-803	PTK_Jak2_rpt1
cd05582	540-793	STKc_RSK_N
cd08222	540-799	STKc_Nek11
cd08218	540-795	STKc_Nek1
cd08223	538-795	STKc_Nek4
cd06628	539-799	STKc_Byr2_like
cd05616	540-766	STKc_cPKC_beta
cd14081	538-801	STKc_BRSK1_2
cd06630	539-799	STKc_MEKK1
cd14187	652-802	STKc_PLK1
cd14188	652-803	STKc_PLK2
cd06655	520-812	STKc_PAK2
cd06629	535-802	STKc_Bck1_like
cd14189	652-801	STKc_PLK3
cd05578	543-798	STKc_Yank1
cd14105	538-766	STKc_DAPK
cd13983	542-802	STKc_WNK
cd06616	542-764	PKc_MKK4
cd06609	542-799	STKc_MST3_like
cd08228	540-752	STKc_Nek6
cd05604	540-816	STKc_SGK3
cd06633	523-803	STKc_TAO3
cd14120	542-798	STKc_ULK1_2-like
cd05570	540-760	STKc_PKC
cd05615	542-766	STKc_cPKC_alpha
cd07860	542-815	STKc_CDK2_3
cd06620	540-799	PKc_Byr1_like
cd14002	543-801	STKc_STK36
cd07838	542-745	STKc_CDK4_6_like
cd05590	540-812	STKc_nPKC_eta
cd14144	540-800	STKc_BMPR1
cd14079	538-740	STKc_AMPK_alpha
cd06605	540-801	PKc_MAPKK
cd06613	542-750	STKc_MAP4K3_like
cd06625	538-799	STKc_MEKK3_like
cd14119	542-801	STKc_LKB1
cd05595	540-762	STKc_PKB_beta
cd14076	538-764	STKc_Kin4
cd07840	542-795	STKc_CDK9_like
cd14047	542-803	STKc_EIF2AK2_PKR
cd13997	542-799	PKc_Wee1_like
cd06659	542-750	STKc_PAK6
cd14117	538-812	STKc_Aurora-B_like
cd14137	540-757	STKc_GSK3
cd07832	538-752	STKc_CCRK
cd06648	542-799	STKc_PAK_II
cd14044	650-807	PK_GC-C
cd14185	538-793	STKc_DCKL3
cd06621	542-795	PKc_Pek1_like
cd14067	581-794	STKc_LRRK1
cd14200	579-800	STKc_CaMKK1
cd14219	535-815	STKc_BMPR1b
cd06654	520-799	STKc_PAK1
cd14042	564-810	PK_GC-A_B
cd05580	538-760	STKc_PKA_like
cd08229	537-797	STKc_Nek7
cd07863	589-745	STKc_CDK4
cd06624	542-802	STKc_ASK
cd14084	533-737	STKc_Chk2
cd14000	582-795	STKc_LRRK
cd14052	540-799	PTKc_Wee1_fungi
cd14012	577-799	PK_eIF2AK_GCN2_rpt1
cd08220	540-799	STKc_Nek8
cd14070	538-798	STKc_HUNK
cd07835	542-758	STKc_CDK1_CdkB_like
cd14039	542-741	STKc_IKK_alpha
cd13986	542-805	STKc_16
cd06656	520-812	STKc_PAK3
cd07830	538-799	STKc_MAK_like
cd13998	543-793	STKc_TGFbR-like
cd14118	542-802	STKc_CAMKK
cd14202	542-799	STKc_ULK1
cd14194	538-757	STKc_DAPK1
cd14053	545-745	STKc_ACVR2
cd06647	542-799	STKc_PAK_I
cd05612	540-765	STKc_PRKX_like
cd14073	534-694	STKc_NUAK
cd13993	542-800	STKc_Pat1_like
cd14038	542-750	STKc_IKK_beta
cd05587	540-759	STKc_cPKC
cd05572	542-793	STKc_cGK
cd13996	542-799	STKc_EIF2AK
cd14054	542-752	STKc_BMPR2_AMHR2
cd06917	542-799	STKc_NAK1_like
cd07831	538-744	STKc_MOK
cd05593	540-762	STKc_PKB_gamma
cd14050	540-799	PKc_Myt1
cd14001	585-805	PKc_TOPK
cd07878	542-770	STKc_p38beta
cd05603	540-771	STKc_SGK2
cd14043	589-799	PK_GC-2D
cd07851	542-768	STKc_p38
cd14142	535-800	STKc_ACVR1_ALK1
cd07861	542-745	STKc_CDK1_euk
cd05602	540-771	STKc_SGK1
cd13989	542-750	STKc_IKK
cd06638	540-799	STKc_myosinIIIA_N
cd06622	542-801	PKc_PBS2_like
cd07836	542-757	STKc_Pho85
cd14074	538-802	STKc_SNRK
cd07880	521-817	STKc_p38gamma
cd14068	542-803	STKc_LRRK2
cd05631	540-750	STKc_GRK4
cd05592	540-793	STKc_nPKC_theta_like
cd13982	540-798	STKc_IRE1
cd14198	617-795	STKc_DRAK2
cd05585	542-784	STKc_YPK1_like
cd14165	538-782	STKc_TSSK1_2-like
cd07877	542-768	STKc_p38alpha
cd05611	540-793	STKc_Rim15_like
cd05630	540-750	STKc_GRK6
cd13995	544-799	STKc_MAP3K8
cd05632	540-752	STKc_GRK5
cd06639	540-801	STKc_myosinIIIB_N
cd05574	540-752	STKc_phototropin_like
cd07865	542-795	STKc_CDK9
cd07855	540-752	STKc_ERK5
cd14071	540-740	STKc_SIK
cd06652	538-799	STKc_MEKK2
cd14162	538-767	STKc_TSSK4-like
cd14159	542-749	STKc_IRAK1
cd14093	565-740	STKc_PhKG
cd06658	542-750	STKc_PAK5
cd07862	542-745	STKc_CDK6
cd07864	542-745	STKc_CDK12
cd06657	542-813	STKc_PAK4
cd14004	540-802	STKc_PASK
cd06635	540-799	STKc_TAO1
cd14195	530-757	STKc_DAPK3
cd07854	540-752	STKc_MAPK4_6
cd06607	654-799	STKc_TAO
cd14095	535-802	STKc_DCKL
cd14184	535-793	STKc_DCKL2
cd14010	626-800	STKc_ULK4
cd06636	538-743	STKc_MAP4K4_6_N
cd13987	542-801	STKc_SBK1
cd07843	544-798	STKc_CDC2L1
cd14209	540-772	STKc_PKA
cd14048	540-801	STKc_EIF2AK3_PERK
cd14098	535-798	STKc_Rad53_Cds1
cd08216	564-750	PK_STRAD
cd14097	539-766	STKc_STK33
cd06637	538-743	STKc_TNIK
cd14201	542-796	STKc_ULK2
cd06619	541-757	PKc_MKK5
cd07871	536-752	STKc_PCTAIRE3
cd14005	538-801	STKc_PIM
cd05608	618-758	STKc_GRK1
cd05591	540-760	STKc_nPKC_epsilon
cd05594	533-762	STKc_PKB_alpha
cd08226	564-758	PK_STRAD_beta
cd06618	644-801	PKc_MKK7
cd14106	539-801	STKc_DRAK
cd07839	542-752	STKc_CDK5
cd14183	530-752	STKc_DCKL1
cd13977	535-799	STKc_PDIK1L
cd07879	540-764	STKc_p38delta
cd05605	619-750	STKc_GRK4_like
cd05577	619-758	STKc_GRK
cd14196	538-757	STKc_DAPK2
cd14191	542-757	STKc_MLCK1
cd06653	538-799	STKc_MEKK3_like_u1
cd14193	542-757	STKc_MLCK4
cd14109	579-765	PK_Unc-89_rpt1
cd13975	593-806	PKc_Dusty
cd13988	542-750	STKc_TBK1
cd13968	563-692	PKc_like
cd07842	543-744	STKc_CDK8_like
cd08221	540-801	STKc_Nek9
cd07849	542-766	STKc_ERK1_2_like
cd05571	540-742	STKc_PKB
cd14077	537-798	STKc_Kin1_2
cd14182	565-798	STKc_PhKG1
cd13994	542-802	STKc_HAL4_like
cd07693	138-223	Ig1_Robo
cd06634	540-795	STKc_TAO2
cd07853	540-762	STKc_NLK
cd14166	540-765	STKc_CaMKI_gamma
cd14192	540-762	STKc_MLCK3
cd07850	540-768	STKc_JNK
cd07867	539-809	STKc_CDC2L6
cd14033	542-765	STKc_WNK4
cd14160	542-806	PK_IRAK3
pfam00041	335-418	fn3
cd05622	525-750	STKc_ROCK1
cd14031	542-799	STKc_WNK3
cd14186	538-750	STKc_PLK4
cd07868	539-744	STKc_CDK8
cd14143	542-800	STKc_TGFbR1_ACVR1b_ACVR1c
cd07873	542-752	STKc_PCTAIRE1
cd14032	542-759	STKc_WNK2_like
cd13990	589-802	STKc_TLK
cd07856	540-752	STKc_Sty1_Hog1
cd05624	526-750	STKc_MRCK_beta
cd05575	540-771	STKc_SGK
cd14141	545-745	STKc_ACVR2a
cd14006	542-738	STKc_MLCK-like
cd05573	538-759	STKc_ROCK_NDR_like
cd05623	507-776	STKc_MRCK_alpha
cd05579	622-760	STKc_MAST_like
cd14011	655-799	PK_SCY1_like
cd14078	537-740	STKc_MELK
cd14104	535-764	STKc_Titin
cd07870	540-755	STKc_PFTAIRE2
cd14030	520-765	STKc_WNK1
cd05621	514-750	STKc_ROCK2
cd07833	541-752	STKc_CDKL
cd14075	538-694	STKc_NIM1
cd14197	532-766	STKc_DRAK1
cd05625	540-750	STKc_LATS1
cd06651	539-799	STKc_MEKK3
cd14167	542-760	STKc_CaMKI_alpha
cd07846	542-799	STKc_CDKL2_3
cd14082	540-760	STKc_PKD
cd14164	538-795	STKc_TSSK6-like
cd05618	538-764	STKc_aPKC_iota
cd08528	537-799	STKc_Nek10
cd05626	540-750	STKc_LATS2
cd05598	540-750	STKc_LATS
cd14103	542-737	STKc_MLCK
cd07872	542-752	STKc_PCTAIRE2
cd07845	542-758	STKc_CDK10
cd14046	540-799	STKc_EIF2AK4_GCN2_rpt2
cd06650	644-758	PKc_MEK1
cd07874	540-768	STKc_JNK3
cd14112	535-737	STKc_Unc-89_rpt2
cd14019	542-793	STKc_Cdc7
cd07858	540-764	STKc_TEY_MAPK
cd07876	540-819	STKc_JNK2
cd14665	540-802	STKc_SnRK2-3
cd14055	540-745	STKc_TGFbR2_like
cd05586	542-812	STKc_Sck1_like
cd07847	538-814	STKc_CDKL1_4
cd05617	538-750	STKc_aPKC_zeta
cd13974	655-805	STKc_SHIK
cd14094	542-798	STKc_CASK
cd14163	538-799	STKc_TSSK3-like
cd05588	540-764	STKc_aPKC
cd05728	53-125	Ig4_Contactin-2-like
cd07875	540-768	STKc_JNK1
cd06615	644-758	PKc_MEK
pfam13895	144-223	Ig_2
cd05613	618-757	STKc_MSK1_N
cd05584	540-793	STKc_p70S6K
cd07857	540-742	STKc_MPK1
cd06646	659-743	STKc_MAP4K5
cd14096	542-742	STKc_RCK1-like
cd05607	618-750	STKc_GRK7
cd06649	542-758	PKc_MEK2
cd07859	542-798	STKc_TDY_MAPK
cd14181	594-750	STKc_PhKG2
pfam00041	227-321	fn3
cd14087	584-766	STKc_PSKH1
cd13991	533-734	STKc_NIK
cd07837	542-812	STKc_CdkB_plant
cd14111	649-750	STKc_SPEG_rpt2
cd14113	542-750	STKc_Trio_C
smart00060	225-318	FN3
cd14132	538-763	STKc_CK2_alpha
cd05629	540-713	STKc_NDR_like_fungal
cd07844	542-757	STKc_PCTAIRE_like
cd06645	538-743	STKc_MAP4K3
cd14168	540-760	STKc_CaMKI_delta
cd14133	628-795	PKc_DYRK_like
cd14110	652-798	STKc_obscurin_rpt2
cd05583	652-757	STKc_MSK_N
cd14179	540-766	STKc_MSK1_C
cd05597	626-750	STKc_DMPK_like
cd14662	540-800	STKc_SnRK2
cd05614	652-757	STKc_MSK2_N
cd05610	618-695	STKc_MASTL
cd14178	594-750	STKc_RSK3_C
cd07852	660-798	STKc_MAPK15-like
cd05601	619-752	STKc_CRIK
cd05609	644-793	STKc_MAST
cd05596	540-750	STKc_ROCK
cd14223	619-750	STKc_GRK2
cd14229	542-824	STKc_HIPK3
cd07848	542-758	STKc_CDKL5
cd05606	603-750	STKc_beta_ARK
cd14176	594-750	STKc_RSK2_C
cd14157	544-744	STKc_IRAK2
cd14177	587-766	STKc_RSK4_C
cd14172	617-754	STKc_MAPKAPK3
cd14100	538-805	STKc_PIM1
cd14140	545-795	STKc_ACVR2b
cd05747	41-119	Ig5_Titin_like
cd14083	653-737	STKc_CaMKI
cd14088	584-801	STKc_CaMK_like
cd14101	538-802	STKc_PIM2
pfam13927	40-119	Ig_3
cd07869	540-755	STKc_PFTAIRE1
cd04978	49-117	Ig4_L1-NrCAM_like
pfam13927	139-209	Ig_3
smart00221	538-803	STYKc
smart00410	145-223	IG_like
pfam07714	536-803	Pkinase_Tyr
smart00219	538-803	TyrKc
smart00220	538-802	S_TKc
pfam00069	538-802	Pkinase
COG0515	538-817	SPS1
PHA03209	523-742	PHA03209
PTZ00024	538-752	PTZ00024
PHA02988	563-804	PHA02988
PHA03212	584-744	PHA03212
PTZ00267	656-799	PTZ00267
PTZ00426	540-765	PTZ00426
PTZ00263	534-771	PTZ00263
PTZ00266	540-883	PTZ00266
PTZ00036	514-742	PTZ00036
PLN00034	589-741	PLN00034
PLN00009	542-758	PLN00009
PHA03210	577-822	PHA03210
smart00410	41-123	IG_like
smart00409	41-123	IG
pfam07679	37-117	I-set
PRK13184	563-811	pknD
PHA03211	585-764	PHA03211
PTZ00283	660-799	PTZ00283
PHA03207	584-748	PHA03207
smart00408	53-119	IGc2
smart00409	145-223	IG
pfam07679	139-223	I-set

Ontology Information

HPRD ID	730
Molecular Class	Receptor tyrosine kinase
Molecular Function	Lyase activity (GO:0016829)
Biological Process	Metabolism (GO:0008152); Energy pathways (GO:0006091)

SNP Information

View SNP Geneview Report

Drug Information

No matching records could be found.

External Links

ArrayExpress GO
ICGC GO
Cancer3D GO
COSMIC GO
NCG GO
TSGene GO
Tumor Gene Family of Databases GO
CCDB GO
G2SBC GO
Osteosarcoma Database GO
RCDB GO

ArrayExpress	GO
ICGC	GO
Cancer3D	GO
COSMIC	GO
NCG	GO
TSGene	GO
Tumor Gene Family of Databases	GO
CCDB	GO
G2SBC	GO
Osteosarcoma Database	GO
RCDB	GO