Search results:
General Information
| Gene_Symbol | Gene_ID | Gene_Name | Chromosome | Alias |
|---|---|---|---|---|
| THSD1 | 55901 | thrombospondin, type I, domain containing 1 | 13 | TMTSP |
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 24976283 | 2014 | Cell line : - Source : - Sample Type : CRC tumor and normal tissue No. of Sample : 30 CRC, 50 CRC and adjacent normal tissue Stage : - | real time RT-PCR, western blotting | Down-regulation | - | Conversely, the mRNA expression levels of YAP, TAZ, TEAD, and OCT4 showed a decreasing tendency from CRC to adjacent nontumorous tissues |
| 22664866 | 2012 | Cell line : HCT116, RKO, Colo320, SW480 and HT29 Source : - Sample Type : CRC tumor and normal tissue No. of Sample : 23 Stage : - | Mthylation-specific PCR, real time RT-PCR | Down-regulation | - | THSD1 mRNA down-regulation was observed in tumor tissues. |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | - |
| Description | The protein encoded by this gene contains a type 1 thrombospondin domain, which is found in a number of proteins involved in the complement pathway, as well as in extracellular matrix proteins. Alternatively spliced transcript variants encoding different isoforms have been observed for this gene. [provided by RefSeq, Jan 2009] |
| Chromosome | 13 |
| Location | 13q14.13 |
| Start | 52934506 |
| End | 52980629 |
| Strand | - |
| Gene Sequence | Download Select all |
| Length | 46124 |
| OMIM ID | - |
| HGNC ID | HGNC:17754 |
| Unigene ID | Hs.325667 |
| Ensembl ID | ENSG00000136114 |
| PharmGKB ID | PA134937912 |
Protein Information
| Protein ID | NP_061146.1 |
|---|---|
| Protein Name | thrombospondin, type I, domain containing 1 |
| Molecular Wt. (Da) | 0 |
| Protein Sequence | Download Select all |
| Length | 852 |
| Uniprot ID | Q9ULP0 |
| Ensembl Protein ID | ENSP00000258187 |
Post-translational Modification Information (Source : HPRD)
No matching records could be found.
Enzyme Information
No matching records could be found.
PPi Information
No STRING Network could be found.
No matching records from HPRD source could be found.
Pathway Information
No matching records could be found.
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| smart00209 | 343-392 | TSP1 |
| cl15278 | 343-392 | TSP_1 superfamily |
| pfam00090 | 344-392 | TSP_1 |
| PTZ00441 | 330-667 | PTZ00441 |
Ontology Information
| HPRD ID | 7802 |
|---|---|
| Molecular Class | Extracellular matrix protein |
| Molecular Function | Transcription factor activity (GO:0003700) |
| Biological Process | Regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism (GO:0019219) |
Drug Information
No matching records could be found.