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General Information
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Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 22941695 | 2012 | Cell line : - Source : - Sample Type : CRC tumor No. of Sample : 23 colorectal biopsy samples (7 normal mucosa, 6 inflammatory mucosa and 10 polyp tissues) and 20 cases of colorectal cancer tissues as well as the adjacent normal tissues. Stage : - | Immunohistochemistry,Real-time PCR | Down-regulation | - | Both apoM mRNA and protein expression levels in colorectal cancer tissues are significantly decreased in contrast to normal and benign colorectal tissues. |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | Apolipoproteins, "Lipocalins" |
| Description | The protein encoded by this gene is an apolipoprotein and member of the lipocalin protein family. It is found associated with high density lipoproteins and to a lesser extent with low density lipoproteins and triglyceride-rich lipoproteins. The encoded protein is secreted through the plasma membrane but remains membrane-bound, where it is involved in lipid transport. Alternate splicing results in both coding and non-coding variants of this gene. [provided by RefSeq, Jan 2012] |
| Chromosome | 6 |
| Location | 6p21 |
| Start | 31620187 |
| End | 31625987 |
| Strand | + |
| Gene Sequence | Download Select all |
| Length | 5801 |
| OMIM ID | 606907 |
| HGNC ID | HGNC:13916 |
| Unigene ID | Hs.534468 |
| Ensembl ID | ENSG00000204444 |
| PharmGKB ID | PA38370 |
Protein Information
| Protein ID | NP_001243098.1 |
|---|---|
| Protein Name | apolipoprotein M |
| Molecular Wt. (Da) | 0 |
| Protein Sequence | Download Select all |
| Length | 188 |
| Uniprot ID | Q9BYT3 |
| Ensembl Protein ID | ENSP00000320754 |
Post-translational Modification Information (Source : HPRD)
| Residue | Type | site |
|---|---|---|
| C | Disulfide Bridge | 128;157 |
| N | Glycosylation | 135 |
| C | Disulfide Bridge | 23;167 |
| C | Disulfide Bridge | 95;183 |
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
No matching records from HPRD source could be found.
Pathway Information
No matching records could be found.
Structure Information
No matching records could be found.
Ontology Information
| HPRD ID | 15689 |
|---|---|
| Molecular Class | Transport/cargo protein |
| Molecular Function | Transcription regulator activity (GO:0030528) |
| Biological Process | Regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism (GO:0019219) |
Drug Information
No matching records could be found.