CoReCG

Evidence Information

Pubmed ID	Year	Sample Information	Techniques	Mechanism	Fold Change	Remark
24222123	2013	Cell line : - Source : - Sample Type : CRC tumor No. of Sample : 53 Stage : -	real time RT-PCR	Down-regulation	-	Six genes were down-regulated: destrin (DSTN), mesoderm induction early response 1, family member 3 (MIER3), acyl-CoA synthetase long-chain family member 5 (ACSL5), mitogen-activated protein kinase 1/ERK (MAPK1), claudin 23 (CLDN23).

Gene Details

NC_000022.10 (22113946..22221970, complement)
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Gene Type	protein coding
Gene Family	Mitogen-activated protein kinase cascade / Kinases
Description	This gene encodes a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. One study also suggests that this protein acts as a transcriptional repressor independent of its kinase activity. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene. [provided by RefSeq, Jan 2014]
Chromosome	22
Location	22q11.2
Start	22113946
End	22221970
Strand	-
Gene Sequence	Download   Select all
Length	108025
OMIM ID	176948
HGNC ID	HGNC:6871
Unigene ID	Hs.431850
Ensembl ID	ENSG00000100030
PharmGKB ID	PA30616

mRNA Information

mRNA ID	?NM_002745.4
Exon	join(1..359,59835..60017,61642..61831,68553..68669, 78873..78987,79293..79424,94699..94808,98361..98486, 103441..108024)
mRNA Sequence	Download   Select all
Length	5916

CDS Information

   

Location	241..1323
CDS Sequence	Download   Select all
CCDS ID	CCDS13795.1

Protein Information

      

Protein ID	NP_002736.3
Protein Name	mitogen-activated protein kinase 1
Molecular Wt. (Da)	38144
Protein Sequence	Download   Select all
Length	360
Uniprot ID	O75084
Ensembl Protein ID	ENSP00000286201

Post-translational Modification Information (Source : HPRD)

Residue	Type	site
Y	Dephosphorylation	187
Y	Dephosphorylation	187
Y	Dephosphorylation	187
T	Phosphorylation	185
Y	Phosphorylation	187
S	Phosphorylation	41
T	Phosphorylation	185
Y	Phosphorylation	187
S	Phosphorylation	41
T	Dephosphorylation	185
Y	Dephosphorylation	187
S	Phosphorylation	29
Y	Dephosphorylation	187
Y	Phosphorylation	187
Y	Phosphorylation	187
Y	Phosphorylation	187
Y	Phosphorylation	187
Y	Phosphorylation	205
Y	Phosphorylation	205
T	Phosphorylation	181
T	Phosphorylation	181
S	Phosphorylation	202
S	Phosphorylation	202
Y	Phosphorylation	186
Y	Phosphorylation	186
T	Phosphorylation	190
T	Phosphorylation	190

Enzyme Information

No matching records could be found.

PPi Information

(Click to view network : Source STRING)      View   

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              

Interactant Gene ID (Source: HPRD)	Gene Symbol	HPRD ID	Ref Seq ID	Technique	References
367	AR	2437	NP_000035.2	in vitro;in vivo	972   591   010   318   905
408	ARRB1	146	NP_004032.2	in vitro	103   471   429   388   255
409	ARRB2	147	NP_004304.1	in vitro	11226259
596	BCL2	1045	NP_000624.2	in vivo	152   256   431   056   757   000   000   000
790	CAD	6437	NP_004332.2	in vitro	12438317
842	CASP9	3756	NP_001220.2	in vitro;in vivo	12792650
857	CAV1	3028	NP_001744.2	in vivo	12388423
930	CD19	113	NP_001761.3	in vitro	10706702
1051	CEBPB	1801	NP_005185.2	in vitro	8384717
1843	DUSP1	2835	NP_004408.1	in vitro;in vivo;yeast 2-hybrid	11   278   799   106   174   600   000   000   000   000   000
1844	DUSP2	4348	NP_004409.1	in vitro	16288922
1847	DUSP5	4349	NP_004410.3	in vitro;in vivo;yeast 2-hybrid	15713638
1848	DUSP6	4124	NP_001937.2	in vitro;in vivo	15632084
1978	EIF4EBP1	3746	NP_004086.1	in vitro;in vivo	9   405   468   808   322   390   000   000   000   000   000   000   000
2057	EPOR	587	NP_000112.1	in vivo	12538595
2077	ERF	9942	NP_006485.2	in vitro;in vivo	10330152
2099	ESR1	589	NP_000116.2	in vitro;in vivo	120   937   459   528   769
2113	ETS1	1260	NP_001137292.1	in vitro	16045329
2213	FCGR2B	6849	NP_003992.3	in vivo	15081531
2353	FOS	1275	NP_005243.1	in vitro;in vivo	7   816   602   824   819   710   000   000
2516	NR5A1	1702	NP_004950.2	in vivo	10230405
2549	GAB1	5116	NP_997006.1	in vitro	15379552
2569	GABRR1	15921	NP_002033.2	in vitro	12175859
2623	GATA1	2372	NP_002040.1	in vitro	15967790
2697	GJA1	414	NP_000156.1	in vitro;in vivo	12   637   502   863   199   400   000   000   000   000
2885	GRB2	150	NP_002077.1	in vivo	8994038
2887	GRB10	3312	NP_005302.3	in vitro;in vivo	15952796
2908	NR3C1	679	NP_001019265.1	in vitro;in vivo	123   517   029   199   329
3164	NR4A1	744	NP_002126.2	in vitro;in vivo	11883936
3299	HSF4	3896	NP_001035757.1	in vivo	16581800
3320	HSP90AA1	777	NP_001017963.2	in vivo	11748628
3454	IFNAR1	126	NP_000620.2	in vitro;in vivo	9029147
3667	IRS1	943	NP_005535.1	in vitro	16131083
3856	KRT8	1015	NP_002264.1	in vitro;in vivo	11   788   583   117   813   200   000   000
3932	LCK	1080	NP_005347.3	in vitro;in vivo	862   656   185   063   648   000   000
3977	LIFR	1048	NP_002301.1	in vivo	7777512
3991	LIPE	1062	NP_005348.2	in vitro	11581251
4043	LRPAP1	82	NP_002328.1	in vitro	15342917
4086	SMAD1	3356	NP_005891.1	in vitro;in vivo	9335504
4087	SMAD2	3221	NP_005892.1	in vitro	10197981
4088	SMAD3	4380	NP_005893.1	in vitro;in vivo	1   615   666   610   197   980
4089	SMAD4	2995	NP_005350.1	in vitro;in vivo	12801888
4155	MBP	1158	NP_001020272.1	in vitro	97   927   051   276   042   200   000   000
4170	MCL1	8870	NP_068779.1	in vitro	15241487
4602	MYB	1810	NP_001123645.1	in vitro;in vivo	8960373
4744	NEFH	1204	NP_066554.2	in vitro;in vivo	9592082
5058	PAK1	3995	AAC24716.1	in vitro;in vivo	15542607
5062	PAK2	5428	NP_002568.2	in vitro	15031289
5327	PLAT	1419	NP_000921.1	in vitro	15861134
5465	PPARA	1369	NP_001001930.1	in vitro	10187842
5468	PPARG	3288	NP_056953.2	in vitro;in vivo	9030579
5499	PPP1CA	15942	NP_001008709.1	in vitro	12624094
5515	PPP2CA	8912	NP_002706.1	in vitro	12624094
5580	PRKCD	1501	NP_006245.2	in vivo	12759139
5590	PRKCZ	1504	NP_002735.3	in vivo	15721486
5604	MAP2K1	1469	NP_002746.1	in vitro;in vivo;yeast 2-hybrid	11   823   456   113   529   100   000   000   000   000   000   000   000   000   000   000
5778	PTPN7	1480	NP_542155.1	in vitro;in vivo	107   027   941   020   698   000   000   000
5894	RAF1	1265	NP_002871.1	in vitro;in vivo	15664191
5925	RB1	1574	NP_000312.2	in vitro	15489336
6195	RPS6KA1	3402	NP_001006666.1	in vitro;in vivo	12   594   221   991   582   600   000   000   000   000   000   000   000
6256	RXRA	1577	NP_002948.1	in vitro;in vivo	12048211
6340	SCNN1G	2862	NP_001030.2	in vitro	11805112
6548	SLC9A1	123	NP_003038.2	in vitro	15253667
6622	SNCA	1227	NP_000336.1	in vivo	11279280
6654	SOS1	1681	NP_005624.2	in vitro;in vivo	8816480
6667	SP1	1796	NP_612482.2	in vitro;in vivo	11904305
6720	SREBF1	1701	NP_001005291.1	in vitro	10915800
6774	STAT3	26	NP_644805.1	in vitro;in vivo	11   350   938   105   215   000   000   000   000   000   000   000   000   000   000   000   000   000   000   000   000
6929	TCF3	918	NP_003191.1	in vivo	14592976
7050	TGIF1	4023	NP_733796.2	in vitro;in vivo	11226163
7132	TNFRSF1A	1861	NP_001056.1	in vitro	11606045
7157	TP53	1859	NP_000537.3	in vitro;in vivo	114   098   761   511   609   000   000   000
7249	TSC2	1850	NP_000539.2	in vitro;in vivo	1   585   102   615   342   910
7343	UBTF	2814	NP_055048.1	in vitro;in vivo	11741541
7409	VAV1	1284	NP_005419.2	in vivo	90   138   738   900   182
7538	ZFP36	1835	NP_003398.1	in vitro;in vivo	776   893   595   286   626
8202	NCOA3	3570	NP_858045.1	in vitro	10866661
8648	NCOA1	4070	NP_003734.3	in vitro;in vivo	10660621
8718	TNFRSF25	4532	NP_683866.1	in vitro;in vivo	11606045
8826	IQGAP1	4541	NP_003861.1	in vitro;in vivo	1.50E+15
8870	IER3	4295	NP_434702.1	in vitro;in vivo	12356731
9846	GAB2	5866	NP_036428.1	in vitro;in vivo	15356145
10044	SH2D3C	5284	NP_733745.1	in vivo	10692442
10140	TOB1	9273	NP_005740.1	in vitro;in vivo;yeast 2-hybrid	1   215   139   612   050   110
10174	SORBS3	11535	NP_005766.3	in vivo	15184391
10287	RGS19	5461	NP_005864.1	in vitro;in vivo	10993892
10657	KHDRBS1	3926	NP_006550.1	in vitro	12478298
10817	FRS3	6373	NP_006644.1	in vitro;in vivo;yeast 2-hybrid	15485655
10818	FRS2	6372	NP_006645.3	in vitro	12419216
23236	PLCB1	6177	NP_056007.1	in vitro	11481231
26003	GORASP2	8303	NP_056345.3	in vitro	11408587
54820	NDE1	14815	NP_060138.1	in vitro	12556484
57658	CALCOCO1	13868	NP_065949.1	in vitro	15489336
80824	DUSP16	9525	NP_085143.1	in vivo	1   148   989   112   794   080
84687	PPP1R9B	4506	NP_115984.3	in vitro;in vivo	15728359
84867	PTPN5	1472	NP_116170.3	in vitro;in vivo	9857190
123920	CMTM3	16259	NP_653202.1	in vivo	15087455
389692	MAFA	14346	NP_963883.2	in vitro;in vivo	11416124

Pathway Information

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              

Pathway Name	Pathway ID
Acute myeloid leukemia	hsa05221
Adherens junction	hsa04520
Adrenergic signaling in cardiomyocytes	hsa04261
AGE-RAGE signaling pathway in diabetic complications	hsa04933
Alcoholism	hsa05034
Aldosterone-regulated sodium reabsorption	hsa04960
Alzheimer's disease	hsa05010
Axon guidance	hsa04360
B cell receptor signaling pathway	hsa04662
Bladder cancer	hsa05219
cAMP signaling pathway	hsa04024
Central carbon metabolism in cancer	hsa05230
cGMP-PKG signaling pathway	hsa04022
Chagas disease (American trypanosomiasis)	hsa05142
Chemokine signaling pathway	hsa04062
Choline metabolism in cancer	hsa05231
Cholinergic synapse	hsa04725
Chronic myeloid leukemia	hsa05220
Circadian entrainment	hsa04713
Colorectal cancer	hsa05210
Dorso-ventral axis formation	hsa04320
Endometrial cancer	hsa05213
ErbB signaling pathway	hsa04012
Estrogen signaling pathway	hsa04915
Fc epsilon RI signaling pathway	hsa04664
Fc gamma R-mediated phagocytosis	hsa04666
Focal adhesion	hsa04510
FoxO signaling pathway	hsa04068
Gap junction	hsa04540
Glioma	hsa05214
Glutamatergic synapse	hsa04724
GnRH signaling pathway	hsa04912
Hepatitis B	hsa05161
Hepatitis C	hsa05160
HIF-1 signaling pathway	hsa04066
Influenza A	hsa05164
Insulin signaling pathway	hsa04910
Leishmaniasis	hsa05140
Long-term depression	hsa04730
Long-term potentiation	hsa04720
MAPK signaling pathway	hsa04010
Melanogenesis	hsa04916
Melanoma	hsa05218
MicroRNAs in cancer	hsa05206
mTOR signaling pathway	hsa04150
Natural killer cell mediated cytotoxicity	hsa04650
Neurotrophin signaling pathway	hsa04722
NOD-like receptor signaling pathway	hsa04621
Non-small cell lung cancer	hsa05223
Oocyte meiosis	hsa04114
Osteoclast differentiation	hsa04380
Oxytocin signaling pathway	hsa04921
Pancreatic cancer	hsa05212
Pathways in cancer	hsa05200
Pertussis	hsa05133
Phospholipase D signaling pathway	hsa04072
PI3K-Akt signaling pathway	hsa04151
Platelet activation	hsa04611
Prion diseases	hsa05020
Progesterone-mediated oocyte maturation	hsa04914
Prolactin signaling pathway	hsa04917
Prostate cancer	hsa05215
Proteoglycans in cancer	hsa05205
Rap1 signaling pathway	hsa04015
Ras signaling pathway	hsa04014
Regulation of actin cytoskeleton	hsa04810
Renal cell carcinoma	hsa05211
Retrograde endocannabinoid signaling	hsa04723
Salmonella infection	hsa05132
Serotonergic synapse	hsa04726
Shigellosis	hsa05131
Signaling pathways regulating pluripotency of stem cells	hsa04550
Sphingolipid signaling pathway	hsa04071
T cell receptor signaling pathway	hsa04660
TGF-beta signaling pathway	hsa04350
Thyroid cancer	hsa05216
Thyroid hormone signaling pathway	hsa04919
TNF signaling pathway	hsa04668
Toll-like receptor signaling pathway	hsa04620
Toxoplasmosis	hsa05145
Tuberculosis	hsa05152
Type II diabetes mellitus	hsa04930
Vascular smooth muscle contraction	hsa04270
VEGF signaling pathway	hsa04370
Viral carcinogenesis	hsa05203

Structure Information

No matching records could be found.

Domain Information

ID	Location	Description
cd07849	19-353	STKc_ERK1_2_like
cl21453	19-353	PKc_like superfamily
cd07834	24-350	STKc_MAPK
cd07858	19-356	STKc_TEY_MAPK
cd07855	19-350	STKc_ERK5
cd07851	18-356	STKc_p38
cd07857	24-350	STKc_MPK1
cd07852	24-350	STKc_MAPK15-like
cd07877	18-356	STKc_p38alpha
cd07856	14-350	STKc_Sty1_Hog1
cd07878	18-356	STKc_p38beta
cd07859	24-356	STKc_TDY_MAPK
cd07880	14-356	STKc_p38gamma
cd07854	19-351	STKc_MAPK4_6
cd07879	12-356	STKc_p38delta
cd07850	24-350	STKc_JNK
cd05118	25-313	STKc_CMGC
cd07829	25-313	STKc_CDK_like
cd07853	31-359	STKc_NLK
cd07841	24-312	STKc_CDK7
cd07876	14-350	STKc_JNK2
cd07830	25-313	STKc_MAK_like
cd14137	21-312	STKc_GSK3
cd07874	19-350	STKc_JNK3
cd07840	25-312	STKc_CDK9_like
cd07832	24-313	STKc_CCRK
cd07875	19-350	STKc_JNK1
cd07843	25-312	STKc_CDC2L1
cd07835	25-313	STKc_CDK1_CdkB_like
cd07838	25-313	STKc_CDK4_6_like
cd07866	24-312	STKc_BUR1
cd07833	24-313	STKc_CDKL
cd07845	25-312	STKc_CDK10
cd07842	24-312	STKc_CDK8_like
cd07836	25-312	STKc_Pho85
cd07844	25-313	STKc_PCTAIRE_like
cd07864	25-313	STKc_CDK12
cd07860	31-312	STKc_CDK2_3
cd07831	25-312	STKc_MOK
cd07839	24-312	STKc_CDK5
cd07861	25-313	STKc_CDK1_euk
cd07870	25-313	STKc_PFTAIRE2
cd07846	24-312	STKc_CDKL2_3
cd07863	24-313	STKc_CDK4
cd07873	25-314	STKc_PCTAIRE1
cd07865	24-312	STKc_CDK9
cd07871	25-313	STKc_PCTAIRE3
cd07847	24-312	STKc_CDKL1_4
cd07837	25-314	STKc_CdkB_plant
cd14132	24-312	STKc_CK2_alpha
cd05117	24-311	STKc_CAMK
cd07862	24-312	STKc_CDK6
cd07872	25-314	STKc_PCTAIRE2
cd00180	31-221	PKc
cd14210	24-313	PKc_DYRK
cd14133	25-313	PKc_DYRK_like
cd07848	24-311	STKc_CDKL5
cd14014	24-310	STKc_PknB_like
cd07869	19-313	STKc_PFTAIRE1
cd05122	25-313	PKc_STE
cd14084	23-313	STKc_Chk2
cd14003	24-312	STKc_AMPK-like
cd06606	24-313	STKc_MAPKKK
cd14007	19-313	STKc_Aurora
cd07867	31-313	STKc_CDC2L6
cd08215	24-313	STKc_Nek
cd07868	31-313	STKc_CDK8
cd14009	31-312	STKc_ATG1_ULK_like
cd14226	24-315	PKc_DYRK1
cd14019	25-313	STKc_Cdc7
cd06614	25-314	STKc_PAK
cd13999	31-234	STKc_MAP3K-like
cd14225	24-313	PKc_DYRK4
cd14099	24-313	STKc_PLK
cd14069	31-313	STKc_Chk1
cd14212	25-313	PKc_YAK1
cd14134	16-313	PKc_CLK
cd14008	31-313	STKc_LKB1_CaMKK
cd05123	31-312	STKc_AGC
cd14080	31-313	STKc_TSSK-like
cd14002	24-313	STKc_STK36
cd14135	24-313	STKc_PRP4
cd14091	71-316	STKc_RSK_C
cd14224	24-313	PKc_DYRK2_3
cd06623	31-318	PKc_MAPKK_plant_like
cd14175	25-315	STKc_RSK1_C
cd14096	24-313	STKc_RCK1-like
cd14093	68-313	STKc_PhKG
cd14098	24-312	STKc_Rad53_Cds1
cd14131	24-313	PKc_Mps1
cd08217	25-313	STKc_Nek2
cd14079	31-313	STKc_AMPK_alpha
cd08530	24-311	STKc_CNK2-like
cd14086	31-315	STKc_CaMKII
cd14081	31-313	STKc_BRSK1_2
cd14229	25-313	STKc_HIPK3
cd14211	25-313	STKc_HIPK
cd14082	31-312	STKc_PKD
cd05578	31-313	STKc_Yank1
cd14121	31-312	STKc_ULK3
cd13996	27-222	STKc_EIF2AK
cd05579	31-314	STKc_MAST_like
cd14119	31-313	STKc_LKB1
cd14663	24-312	STKc_SnRK3
cd14162	31-313	STKc_TSSK4-like
cd06627	31-313	STKc_Cdc7_like
cd06612	17-313	STKc_MST1_2
cd14182	55-316	STKc_PhKG1
cd06625	31-226	STKc_MEKK3_like
cd14006	31-312	STKc_MLCK-like
cd06624	31-313	STKc_ASK
cd08529	25-244	STKc_FA2-like
cd14176	31-313	STKc_RSK2_C
cd14178	31-313	STKc_RSK3_C
cd14177	31-313	STKc_RSK4_C
cd06621	28-313	PKc_Pek1_like
cd13993	24-302	STKc_Pat1_like
cd14165	31-313	STKc_TSSK1_2-like
cd00192	30-224	PTKc
cd13994	31-313	STKc_HAL4_like
cd14213	24-313	PKc_CLK1_4
cd06626	24-313	STKc_MEKK4
cd08218	24-223	STKc_Nek1
cd14046	24-310	STKc_EIF2AK4_GCN2_rpt2
cd14136	16-313	STKc_SRPK
cd14228	25-313	STKc_HIPK1
cd14227	25-313	STKc_HIPK2
cd06607	24-315	STKc_TAO
cd06917	25-226	STKc_NAK1_like
cd14167	31-313	STKc_CaMKI_alpha
cd06610	31-312	STKc_OSR1_SPAK
cd05581	30-312	STKc_PDK1
cd08224	24-238	STKc_Nek6_7
cd08225	24-237	STKc_Nek5
cd14181	46-313	STKc_PhKG2
cd06609	24-316	STKc_MST3_like
cd14120	31-312	STKc_ULK1_2-like
cd14106	31-313	STKc_DRAK
cd13990	24-312	STKc_TLK
cd05580	31-228	STKc_PKA_like
cd06632	31-313	STKc_MEKK1_plant
cd14094	61-313	STKc_CASK
cd14179	31-324	STKc_MSK1_C
cd14164	25-313	STKc_TSSK6-like
cd06608	31-313	STKc_myosinIII_N_like
cd14118	31-312	STKc_CAMKK
cd14169	31-313	STKc_CaMKI_beta
cd14166	31-313	STKc_CaMKI_gamma
cd14083	31-312	STKc_CaMKI
cd14076	22-313	STKc_Kin4
cd06630	31-226	STKc_MEKK1
cd14087	24-313	STKc_PSKH1
cd08223	24-313	STKc_Nek4
cd08528	25-252	STKc_Nek10
cd14073	24-313	STKc_NUAK
cd14095	31-312	STKc_DCKL
cd05611	97-312	STKc_Rim15_like
cd06628	29-313	STKc_Byr2_like
cd14184	31-312	STKc_DCKL2
cd06631	31-313	STKc_YSK4
cd06653	31-312	STKc_MEKK3_like_u1
cd14201	25-314	STKc_ULK2
cd14111	25-313	STKc_SPEG_rpt2
cd06605	27-316	PKc_MAPKK
cd14202	31-314	STKc_ULK1
cd14194	70-313	STKc_DAPK1
cd06611	31-318	STKc_SLK_like
cd08219	24-228	STKc_Nek3
cd06629	124-313	STKc_Bck1_like
cd14161	24-233	STKc_NUAK2
cd14092	68-323	STKc_MSK_C
cd14214	24-313	PKc_CLK3
cd14105	70-313	STKc_DAPK
cd14058	31-228	STKc_TAK1
cd06633	25-240	STKc_TAO3
cd06613	25-312	STKc_MAP4K3_like
cd14085	25-313	STKc_CaMKIV
cd06648	23-313	STKc_PAK_II
cd14010	31-312	STKc_ULK4
cd14185	71-312	STKc_DCKL3
cd06617	31-315	PKc_MKK3_6
cd14186	25-313	STKc_PLK4
cd13997	24-311	PKc_Wee1_like
cd05573	31-314	STKc_ROCK_NDR_like
cd06647	24-314	STKc_PAK_I
cd14196	70-313	STKc_DAPK2
cd06635	25-349	STKc_TAO1
cd14199	24-313	STKc_CaMKK2
cd14195	70-314	STKc_DAPK3
cd08220	24-311	STKc_Nek8
cd14187	24-228	STKc_PLK1
cd14097	25-313	STKc_STK33
cd14048	31-222	STKc_EIF2AK3_PERK
cd05586	31-221	STKc_Sck1_like
cd14114	24-313	STKc_Twitchin_like
cd14047	25-223	STKc_EIF2AK2_PKR
cd13982	50-312	STKc_IRE1
cd05034	31-232	PTKc_Src_like
cd14171	49-313	STKc_MAPKAPK5
cd05038	26-223	PTKc_Jak_rpt2
cd14066	31-226	STKc_IRAK
cd14049	25-222	STKc_EIF2AK1_HRI
cd14116	31-313	STKc_Aurora-A
cd14189	25-313	STKc_PLK3
cd06620	28-326	PKc_Byr1_like
cd14077	31-313	STKc_Kin1_2
cd13985	31-222	STKc_GAK_like
cd14050	25-311	PKc_Myt1
cd06652	31-264	STKc_MEKK2
cd14071	31-313	STKc_SIK
cd06634	25-350	STKc_TAO2
cd14107	31-313	STKc_obscurin_rpt1
cd05572	31-278	STKc_cGK
cd14183	21-313	STKc_DCKL1
cd05063	31-239	PTKc_EphR_A2
cd06659	18-315	STKc_PAK6
cd14200	24-313	STKc_CaMKK1
cd14198	121-313	STKc_DRAK2
cd06655	20-314	STKc_PAK2
cd13978	31-251	STKc_RIP
cd14089	31-312	STKc_MAPKAPK
cd14163	31-222	STKc_TSSK3-like
cd05585	128-315	STKc_YPK1_like
cd14104	31-315	STKc_Titin
cd14090	31-312	STKc_Mnk
cd13979	27-232	STKc_Mos
cd08228	31-247	STKc_Nek6
cd06656	18-314	STKc_PAK3
cd06654	18-251	STKc_PAK1
cd14052	24-311	PTKc_Wee1_fungi
cd14188	24-313	STKc_PLK2
cd14110	25-313	STKc_obscurin_rpt2
cd05060	31-223	PTKc_Syk_like
cd14173	31-313	STKc_Mnk2
cd05584	28-343	STKc_p70S6K
cd05148	31-223	PTKc_Srm_Brk
cd14103	31-313	STKc_MLCK
cd14158	19-228	STKc_IRAK4
cd14005	24-313	STKc_PIM
cd13986	24-310	STKc_16
cd05072	31-230	PTKc_Lyn
cd14197	132-313	STKc_DRAK1
cd14209	25-228	STKc_PKA
cd14190	31-313	STKc_MLCK2
cd13983	31-225	STKc_WNK
cd05039	31-223	PTKc_Csk_like
cd06658	27-320	STKc_PAK5
cd14216	24-313	STKc_SRPK1
cd14665	24-222	STKc_SnRK2-3
cd05602	28-327	STKc_SGK1
cd13989	31-229	STKc_IKK
cd14004	25-313	STKc_PASK
cd05612	31-231	STKc_PRKX_like
cd14180	31-305	STKc_MSK2_C
cd14108	31-313	STKc_SPEG_rpt1
cd14070	31-313	STKc_HUNK
cd14078	31-313	STKc_MELK
cd06642	25-232	STKc_STK25
cd14215	24-313	PKc_CLK2
cd06643	31-327	STKc_SLK
cd13991	31-223	STKc_NIK
cd13995	30-313	STKc_MAP3K8
cd14168	15-313	STKc_CaMKI_delta
cd14072	24-306	STKc_MARK
cd14039	31-226	STKc_IKK_alpha
cd05073	31-230	PTKc_Hck
cd14038	31-301	STKc_IKK_beta
cd06651	31-264	STKc_MEKK3
cd05071	31-237	PTKc_Src
cd14074	31-313	STKc_SNRK
cd14037	30-218	STKc_NAK_like
cd14203	31-237	PTKc_Src_Fyn_like
cd06640	25-240	STKc_MST4
cd06616	26-237	PKc_MKK4
cd14053	51-261	STKc_ACVR2
cd05599	28-228	STKc_NDR_like
cd14117	31-314	STKc_Aurora-B_like
cd08222	132-313	STKc_Nek11
cd06644	31-327	STKc_STK10
cd05066	31-226	PTKc_EphR_A
cd05041	31-223	PTKc_Fes_like
cd05033	31-226	PTKc_EphR
cd05069	31-230	PTKc_Yes
cd05059	26-223	PTKc_Tec_like
cd05065	31-226	PTKc_EphR_B
cd14205	28-268	PTKc_Jak2_rpt2
cd14016	24-172	STKc_CK1
cd05068	28-239	PTKc_Frk_like
cd06615	131-229	PKc_MEK
cd05582	31-278	STKc_RSK_N
cd05570	106-312	STKc_PKC
cd05577	31-237	STKc_GRK
cd06636	31-313	STKc_MAP4K4_6_N
cd14088	65-313	STKc_CaMK_like
cd14075	31-223	STKc_NIM1
cd05067	31-230	PTKc_Lck_Blk
cd14061	31-230	STKc_MLK
cd05084	31-223	PTKc_Fes
cd14059	31-223	STKc_MAP3K12_13
cd14193	31-313	STKc_MLCK4
cd14174	31-314	STKc_Mnk1
cd14218	16-313	STKc_SRPK3
cd08221	117-228	STKc_Nek9
cd14060	32-230	STKc_MLTK
cd05082	31-223	PTKc_Csk
cd05055	23-223	PTKc_PDGFR
cd14036	31-218	STKc_GAK
cd05103	105-232	PTKc_VEGFR2
cd05605	132-228	STKc_GRK4_like
cd06622	28-319	PKc_PBS2_like
cd06650	133-315	PKc_MEK1
cd05604	28-299	STKc_SGK3
cd05575	132-298	STKc_SGK
cd13987	31-310	STKc_SBK1
cd05085	31-223	PTKc_Fer
cd05079	31-223	PTKc_Jak1_rpt2
cd05070	31-258	PTKc_Fyn
cd05600	115-314	STKc_Sid2p_like
cd05112	31-223	PTKc_Itk
cd05587	106-230	STKc_cPKC
cd06657	27-320	STKc_PAK4
cd05040	31-223	PTKc_Ack_like
cd06641	25-226	STKc_MST3
cd14000	31-301	STKc_LRRK
cd14109	69-313	PK_Unc-89_rpt1
cd05102	91-223	PTKc_VEGFR3
cd05603	31-241	STKc_SGK2
cd08229	31-250	STKc_Nek7
cd14146	31-223	STKc_MLK4
cd06638	11-240	STKc_myosinIIIA_N
cd06618	27-326	PKc_MKK7
cd05609	128-230	STKc_MAST
cd14662	24-222	STKc_SnRK2
cd13977	24-301	STKc_PDIK1L
cd14145	31-230	STKc_MLK1
cd05054	31-223	PTKc_VEGFR
cd14192	71-313	STKc_MLCK3
cd14001	52-223	PKc_TOPK
cd05105	104-223	PTKc_PDGFR_alpha
cd14062	31-237	STKc_Raf
cd05608	31-228	STKc_GRK1
cd05057	31-223	PTKc_EGFR_like
cd06619	31-325	PKc_MKK5
cd14041	24-313	STKc_TLK2
cd14115	31-312	STKc_Kalirin_C
cd05598	25-228	STKc_LATS
cd05081	28-234	PTKc_Jak3_rpt2
cd05607	25-228	STKc_GRK7
cd06646	25-313	STKc_MAP4K5
cd05083	31-223	PTKc_Chk
cd05616	96-231	STKc_cPKC_beta
cd14221	31-222	STKc_LIMK1
cd05595	112-232	STKc_PKB_beta
cd05614	102-360	STKc_MSK2_N
cd14011	70-314	PK_SCY1_like
cd05114	31-223	PTKc_Tec_Rlk
cd06637	110-313	STKc_TNIK
cd05632	31-231	STKc_GRK5
cd06645	31-315	STKc_MAP4K3
cd14664	31-227	STK_BAK1_like
cd05097	31-223	PTKc_DDR_like
cd14054	31-231	STKc_BMPR2_AMHR2
cd05107	121-223	PTKc_PDGFR_beta
cd14207	111-223	PTKc_VEGFR1
cd05606	106-237	STKc_beta_ARK
cd14172	93-313	STKc_MAPKAPK3
cd05630	31-228	STKc_GRK6
cd05080	31-223	PTKc_Tyk2_rpt2
cd14040	24-313	STKc_TLK1
cd05053	31-223	PTKc_FGFR
cd14113	25-223	STKc_Trio_C
cd05589	136-230	STKc_PKN
cd14012	65-252	PK_eIF2AK_GCN2_rpt1
cd05619	128-340	STKc_nPKC_theta
cd05116	89-223	PTKc_Syk
cd14148	31-223	STKc_MLK2
cd14065	31-229	PKc_LIMK_like
cd14170	133-324	STKc_MAPKAPK2
cd14033	31-226	STKc_WNK4
cd05621	25-222	STKc_ROCK2
cd14220	31-259	STKc_BMPR1a
cd05056	31-223	PTKc_FAK
cd14112	24-313	STKc_Unc-89_rpt2
cd05571	120-314	STKc_PKB
cd14144	31-261	STKc_BMPR1
cd13998	31-223	STKc_TGFbR-like
cd05051	31-223	PTKc_DDR
cd05593	28-232	STKc_PKB_gamma
cd05601	101-312	STKc_CRIK
cd05044	30-278	PTKc_c-ros
cd14217	24-313	STKc_SRPK2
cd06649	133-229	PKc_MEK2
cd05058	31-241	PTKc_Met_Ron
cd05620	101-230	STKc_nPKC_delta
cd14025	31-244	STKc_RIP4_like
cd05583	108-312	STKc_MSK_N
cd14156	50-229	PKc_LIMK_like_unk
cd14100	18-222	STKc_PIM1
cd06639	31-314	STKc_myosinIIIB_N
cd05590	106-241	STKc_nPKC_eta
cd05592	132-230	STKc_nPKC_theta_like
cd05626	25-228	STKc_LATS2
cd14055	51-223	STKc_TGFbR2_like
cd14150	28-242	STKc_A-Raf
cd05615	106-231	STKc_cPKC_alpha
cd05104	129-230	PTKc_Kit
cd05631	31-228	STKc_GRK4
cd13988	31-248	STKc_TBK1
cd14056	31-222	STKc_TGFbR_I
cd05098	31-230	PTKc_FGFR1
cd14026	27-228	STKc_RIP2
cd05075	31-266	PTKc_Axl
cd05032	31-223	PTKc_InsR_like
cd05633	104-237	STKc_GRK3
cd05113	26-223	PTKc_Btk_Bmx
cd14223	104-243	STKc_GRK2
cd14154	31-222	STKc_LIMK
cd14155	68-223	PKc_TESK
cd05596	31-222	STKc_ROCK
cd05618	112-302	STKc_aPKC_iota
cd14191	31-313	STKc_MLCK1
cd14068	30-223	STKc_LRRK2
cd05628	25-228	STKc_NDR1
cd05043	119-223	PTK_Ryk
cd05095	31-223	PTKc_DDR2
cd05613	115-330	STKc_MSK1_N
cd05099	131-230	PTKc_FGFR4
cd14031	31-224	STKc_WNK3
cd05115	31-233	PTKc_Zap-70
cd05106	105-230	PTKc_CSF-1R
cd08216	37-224	PK_STRAD
cd05594	112-232	STKc_PKB_alpha
cd05625	25-228	STKc_LATS1
cd05574	31-241	STKc_phototropin_like
cd05588	106-228	STKc_aPKC
cd14222	31-222	STKc_LIMK2
cd14101	25-314	STKc_PIM2
cd05627	25-228	STKc_NDR2
cd14159	31-225	STKc_IRAK1
cd05610	31-313	STKc_MASTL
cd05046	25-223	PTK_CCK4
cd05049	31-223	PTKc_Trk
cd14017	24-193	STKc_TTBK
cd05622	25-222	STKc_ROCK1
cd14042	51-221	PK_GC-A_B
cd14219	31-259	STKc_BMPR1b
cd05591	128-330	STKc_nPKC_epsilon
cd05101	131-230	PTKc_FGFR2
cd05096	31-223	PTKc_DDR1
cd14147	31-230	STKc_MLK3
cd05617	112-228	STKc_aPKC_zeta
cd05047	31-223	PTKc_Tie
cd14141	55-223	STKc_ACVR2a
cd05109	132-223	PTKc_HER2
cd05108	31-223	PTKc_EGFR
cd05100	131-230	PTKc_FGFR3
cd13980	25-228	STKc_Vps15
cd13992	32-222	PK_GC
cd14027	34-252	STKc_RIP1
cd14151	12-242	STKc_B-Raf
cd14020	119-313	STKc_KIS
cd05624	28-222	STKc_MRCK_beta
cd05092	31-223	PTKc_TrkA
cd05110	31-233	PTKc_HER4
cd14102	129-222	STKc_PIM3
cd14142	31-221	STKc_ACVR1_ALK1
cd14064	31-223	PKc_TNNI3K
cd05045	129-230	PTKc_RET
cd14030	31-224	STKc_WNK1
cd05089	31-223	PTKc_Tie1
cd05093	31-223	PTKc_TrkB
cd14149	28-242	STKc_C-Raf
cd14067	131-258	STKc_LRRK1
cd14140	51-261	STKc_ACVR2b
cd05048	31-223	PTKc_Ror
cd14013	132-313	STKc_SNT7_plant
cd05623	28-241	STKc_MRCK_alpha
TIGR03724	66-180	arch_bud32
COG3642	67-180	Bud32
smart00220	25-313	S_TKc
pfam00069	25-313	Pkinase
PTZ00024	19-331	PTZ00024
PLN00009	24-314	PLN00009
PTZ00036	24-346	PTZ00036
COG0515	25-360	SPS1
smart00221	26-224	STYKc
smart00219	26-224	TyrKc
pfam07714	31-240	Pkinase_Tyr
PTZ00284	13-317	PTZ00284
PHA03210	24-311	PHA03210
PTZ00263	31-312	PTZ00263
PHA03209	68-311	PHA03209
PRK13184	24-229	pknD
PTZ00426	24-254	PTZ00426
PHA03212	34-324	PHA03212
PLN00034	31-315	PLN00034
PTZ00267	129-314	PTZ00267
PHA03207	21-311	PHA03207
PHA03390	99-313	pk1
TIGR03903	50-230	TOMM_kin_cyc
PHA03211	61-220	PHA03211
PTZ00283	132-241	PTZ00283
PTZ00266	71-237	PTZ00266

Ontology Information

   

HPRD ID	6919
Molecular Class	Serine/threonine kinase
Molecular Function	Calcium ion binding (GO:0005509)
Biological Process	Cell communication (GO:0007154); Signal transduction (GO:0007165)

SNP Information

View SNP Geneview Report