CoReCG

Evidence Information

Pubmed ID	Year	Sample Information	Techniques	Mechanism	Fold Change	Remark
20808308	2010	Cell line : - Source : - Sample Type : CRC tumor No. of Sample : 718 Stage : -	Immunohistochemistry,Methylation analyses,Sequencing, MSI analysis	Phosphorylation	-	Phosphorylated AMPK expression in colorectal cancer is associated with superior prognosis among p-MAPK3/1-positive cases, but not among p-MAPK3/1-negative cases. Utilised the databases of two independent, prospective cohort studies.
23027623	2012	Cell line : - Source : Twin Cities Metropolitan Area, a seven-county area of Utah, Kaiser Permanente Medical Care Program of Northern California (KPMCP). Sample Type : Population-based case-control studies No. of Sample : Colon 1555 , 1956 controls, rectal 754, 959 controls Stage : -	Genotyping	Polymorhpism	-	Mitogen-activated protein kinase (MAPK) pathways regulate many cellular functions including cell proliferation, differentiation, migration and apoptosis. Population-based case-control studies, using data from population-based case-control studies (colon: n = 1555 cases, 1956 controls; rectal: n = 754 cases, 959 controls).

Gene Details

NC_000016.9 (30125426..30134630, complement)
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Gene Type	protein coding
Gene Family	Mitogen-activated protein kinase cascade / Kinases
Description	The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act in a signaling cascade that regulates various cellular processes such as proliferation, differentiation, and cell cycle progression in response to a variety of extracellular signals. This kinase is activated by upstream kinases, resulting in its translocation to the nucleus where it phosphorylates nuclear targets. Alternatively spliced transcript variants encoding different protein isoforms have been described. [provided by RefSeq, Jul 2008]
Chromosome	16
Location	16p11.2
Start	30125426
End	30134630
Strand	-
Gene Sequence	Download   Select all
Length	9205
OMIM ID	601795
HGNC ID	HGNC:6877
Unigene ID	Hs.861
Ensembl ID	ENSG00000102882
PharmGKB ID	PA30622

mRNA Information

mRNA ID	?NM_001040056.2
Exon	join(1..270,1304..1486,4772..4961,5147..5263,5526..5640, 6307..6416,6520..6674,8602..9205)
mRNA Sequence	Download   Select all
Length	1770

CDS Information

   

Location	101..1108
CDS Sequence	Download   Select all
CCDS ID	CCDS10672.1

Protein Information

      

Protein ID	NP_001035145.1
Protein Name	mitogen-activated protein kinase 3
Molecular Wt. (Da)	15596
Protein Sequence	Download   Select all
Length	379
Uniprot ID	Q9Y6D9
Ensembl Protein ID	ENSP00000265854

Post-translational Modification Information (Source : HPRD)

Residue	Type	site
T	Phosphorylation	202
Y	Phosphorylation	204
T	Phosphorylation	202
Y	Phosphorylation	204
Y	Phosphorylation	204
Y	Phosphorylation	204
T	Phosphorylation	202;-
Y	Phosphorylation	203
Y	Phosphorylation	203

Enzyme Information

No matching records could be found.

PPi Information

(Click to view network : Source STRING)      View   

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                     

Interactant Gene ID (Source: HPRD)	Gene Symbol	HPRD ID	Ref Seq ID	Technique	References
156	ADRBK1	182	NP_001610.2	in vitro;in vivo	1   057   491   310   727   520
408	ARRB1	146	NP_004032.2	in vitro	103   471   429   388   255
476	ATP1A1	1662	NP_000692.2	in vitro	15069082
708	C1QBP	3168	NP_001203.1	in vitro;in vivo	11866440
842	CASP9	3756	NP_001220.2	in vitro;in vivo	12792650
1432	MAPK14	2619	NP_001306.1	in vitro;in vivo	12697810
1612	DAPK1	2902	NP_004929.2	in vitro;in vivo	15616583
1630	DCC	391	NP_005206.2	in vitro;in vivo	11986622
1827	RCAN1	4226	NP_004405.3	in vitro	12063245
1843	DUSP1	2835	NP_004408.1	in vitro;in vivo	1   127   879   910   617   460
1845	DUSP3	2553	NP_004081.1	in vitro;in vivo	10224087
2002	ELK1	2407	NP_005220.2	in vitro;in vivo	82   085   311   247   366   000   000   000
2057	EPOR	587	NP_000112.1	in vivo	12538595
2113	ETS1	1260	NP_001137292.1	in vitro	1   194   841   412   048   210
2213	FCGR2B	6849	NP_003992.3	in vivo	15081531
2549	GAB1	5116	NP_997006.1	in vitro	15379552
2697	GJA1	414	NP_000156.1	in vitro;in vivo	12   637   502   863   199   400   000   000   000   000
2764	GMFB	3420	AAH05359.1	in vivo	8639570
2969	GTF2I	3399	NP_127492.1	in vitro;in vivo	10648599
3161	HMMR	2963	NP_001136028.1	in vitro	11403955
3297	HSF1	778	NP_005517.1	in vitro;in vivo	8940068
3299	HSF4	3896	NP_001035757.1	in vivo	16581800
3643	INSR	975	NP_000199.2	in vivo	11409918
3725	JUN	1302	NP_002219.1	in vivo;yeast 2-hybrid	1922387
3856	KRT8	1015	NP_002264.1	in vitro;in vivo	117   885   831   178   132   000   000   000   000   000
3925	STMN1	1047	NP_001138926.1	in vivo	8   376   365   111   353   640   000   000
3932	LCK	1080	NP_005347.3	in vitro;in vivo	85   063   648   618   896
3991	LIPE	1062	NP_005348.2	in vitro	11581251
4043	LRPAP1	82	NP_002328.1	in vitro	15342917
4067	LYN	1301	NP_002341.1	in vivo	11131153
4087	SMAD2	3221	NP_005892.1	in vitro;in vivo	1   219   359   511   027   280
4609	MYC	1818	NP_002458.2	in vitro	9155018
4638	MYLK	2952	NP_444253.3	in vitro	10402467
4916	NTRK3	1870	NP_001012338.1	in vitro	11205744
5062	PAK2	5428	NP_002568.2	in vitro	12226077
5148	PDE6G	8914	NP_002593.1	in vitro	12624098
5327	PLAT	1419	NP_000921.1	in vitro	15861134
5465	PPARA	1369	NP_001001930.1	in vitro	10187842
5499	PPP1CA	15942	NP_001008709.1	in vitro	12624094
5515	PPP2CA	8912	NP_002706.1	in vitro	12624094
5580	PRKCD	1501	NP_006245.2	in vivo	12759139
5581	PRKCE	1500	NP_005391.1	in vivo	1   646   192   616   810   320
5590	PRKCZ	1504	NP_002735.3	in vivo	15721486
5604	MAP2K1	1469	NP_002746.1	in vitro;in vivo	1   074   818   786   267   670   000   000
5778	PTPN7	1480	NP_542155.1	in vitro;in vivo	105   599   441   020   698   000   000   000
5829	PXN	3937	BAA18998.1	in vitro	11784715
5894	RAF1	1265	NP_002871.1	in vitro	9446616
5900	RALGDS	3371	NP_006257.1	in vitro	9155018
6195	RPS6KA1	3402	NP_001006666.1	in vitro;in vivo	128   324   679   915   826
6196	RPS6KA2	3403	NP_001006933.1	in vitro;in vivo	8939914
6197	RPS6KA3	2092	NP_004577.1	in vivo	128   324   679   915   826
6198	RPS6KB1	10202	NP_003152.1	in vitro;in vivo	11279232
6667	SP1	1796	NP_612482.2	in vitro;in vivo	11904305
6689	SPIB	6007	Q01892	in vitro	8632909
6720	SREBF1	1701	NP_001005291.1	in vitro	10915800
6721	SREBF2	2726	NP_004590.2	in vitro	10627507
6774	STAT3	26	NP_644805.1	in vitro;in vivo	11   350   938   105   215   000   000   000   000   000   000   000   000   000   000   000   000   000   000   000   000
6776	STAT5A	3301	NP_003143.2	in vitro;in vivo	10194762
6886	TAL1	1753	NP_003180.1	in vitro	8423803
6887	TAL2	1735	NP_005412.1	in vitro	8152805
6929	TCF3	918	NP_003191.1	in vivo	14592976
7050	TGIF1	4023	NP_733796.2	in vitro;in vivo	11226163
7054	TH	1865	NP_954986.2	in vivo	1347949
7155	TOP2B	537	NP_001059.2	in vitro	9155018
7157	TP53	1859	NP_000537.3	in vivo	10958792
7249	TSC2	1850	NP_000539.2	in vitro	15342917
7343	UBTF	2814	NP_055048.1	in vitro;in vivo	11741541
7553	ZNF7	1918	NP_003407.1	in vitro	9155018
8030	CCDC6	9064	NP_005427.2	in vitro;in vivo	147   122   161   530   293   000   000   000
8569	MKNK1	9468	NP_003675.2	in vitro;in vivo	9155018
9846	GAB2	5866	NP_036428.1	in vitro;in vivo	15356145
11075	STMN2	9003	NP_008960.2	in vitro	95   259   569   126   608
23236	PLCB1	6177	NP_056007.1	in vivo	11287604
26353	HSPB8	6420	NP_055180.1	in vitro	11342557
84867	PTPN5	1472	NP_116170.3	in vitro;in vivo	9857190

Pathway Information

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        

Pathway Name	Pathway ID
Acute myeloid leukemia	hsa05221
Adherens junction	hsa04520
Adrenergic signaling in cardiomyocytes	hsa04261
AGE-RAGE signaling pathway in diabetic complications	hsa04933
Alcoholism	hsa05034
Aldosterone-regulated sodium reabsorption	hsa04960
Alzheimer's disease	hsa05010
Axon guidance	hsa04360
B cell receptor signaling pathway	hsa04662
Bladder cancer	hsa05219
cAMP signaling pathway	hsa04024
Central carbon metabolism in cancer	hsa05230
cGMP-PKG signaling pathway	hsa04022
Chagas disease (American trypanosomiasis)	hsa05142
Chemokine signaling pathway	hsa04062
Choline metabolism in cancer	hsa05231
Cholinergic synapse	hsa04725
Chronic myeloid leukemia	hsa05220
Circadian entrainment	hsa04713
Colorectal cancer	hsa05210
Dorso-ventral axis formation	hsa04320
Endometrial cancer	hsa05213
ErbB signaling pathway	hsa04012
Estrogen signaling pathway	hsa04915
Fc epsilon RI signaling pathway	hsa04664
Fc gamma R-mediated phagocytosis	hsa04666
Focal adhesion	hsa04510
FoxO signaling pathway	hsa04068
Gap junction	hsa04540
Glioma	hsa05214
Glutamatergic synapse	hsa04724
GnRH signaling pathway	hsa04912
Hepatitis B	hsa05161
Hepatitis C	hsa05160
HIF-1 signaling pathway	hsa04066
Influenza A	hsa05164
Insulin signaling pathway	hsa04910
Leishmaniasis	hsa05140
Long-term depression	hsa04730
Long-term potentiation	hsa04720
MAPK signaling pathway	hsa04010
Melanogenesis	hsa04916
Melanoma	hsa05218
mTOR signaling pathway	hsa04150
Natural killer cell mediated cytotoxicity	hsa04650
Neurotrophin signaling pathway	hsa04722
NOD-like receptor signaling pathway	hsa04621
Non-small cell lung cancer	hsa05223
Oocyte meiosis	hsa04114
Osteoclast differentiation	hsa04380
Oxytocin signaling pathway	hsa04921
Pancreatic cancer	hsa05212
Pathways in cancer	hsa05200
Pertussis	hsa05133
Phospholipase D signaling pathway	hsa04072
PI3K-Akt signaling pathway	hsa04151
Platelet activation	hsa04611
Prion diseases	hsa05020
Progesterone-mediated oocyte maturation	hsa04914
Prolactin signaling pathway	hsa04917
Prostate cancer	hsa05215
Proteoglycans in cancer	hsa05205
Rap1 signaling pathway	hsa04015
Ras signaling pathway	hsa04014
Regulation of actin cytoskeleton	hsa04810
Renal cell carcinoma	hsa05211
Retrograde endocannabinoid signaling	hsa04723
Salmonella infection	hsa05132
Serotonergic synapse	hsa04726
Shigellosis	hsa05131
Signaling pathways regulating pluripotency of stem cells	hsa04550
Sphingolipid signaling pathway	hsa04071
T cell receptor signaling pathway	hsa04660
TGF-beta signaling pathway	hsa04350
Thyroid cancer	hsa05216
Thyroid hormone signaling pathway	hsa04919
TNF signaling pathway	hsa04668
Toll-like receptor signaling pathway	hsa04620
Toxoplasmosis	hsa05145
Tuberculosis	hsa05152
Type II diabetes mellitus	hsa04930
Vascular smooth muscle contraction	hsa04270
VEGF signaling pathway	hsa04370
Viral carcinogenesis	hsa05203

Structure Information

No matching records could be found.

Domain Information

ID	Location	Description
cd07849	36-370	STKc_ERK1_2_like
cl21453	36-370	PKc_like superfamily
cd07834	41-367	STKc_MAPK
cd07858	36-373	STKc_TEY_MAPK
cd07855	36-367	STKc_ERK5
cd07851	28-373	STKc_p38
cd07857	41-367	STKc_MPK1
cd07852	41-367	STKc_MAPK15-like
cd07877	36-373	STKc_p38alpha
cd07856	31-367	STKc_Sty1_Hog1
cd07878	36-373	STKc_p38beta
cd07854	36-368	STKc_MAPK4_6
cd07880	36-373	STKc_p38gamma
cd07859	41-373	STKc_TDY_MAPK
cd07879	41-373	STKc_p38delta
cd07829	42-330	STKc_CDK_like
cd07850	41-367	STKc_JNK
cd05118	42-330	STKc_CMGC
cd07853	48-366	STKc_NLK
cd14137	38-329	STKc_GSK3
cd07841	41-340	STKc_CDK7
cd07840	42-329	STKc_CDK9_like
cd07876	31-367	STKc_JNK2
cd07874	36-367	STKc_JNK3
cd07830	42-330	STKc_MAK_like
cd07832	41-330	STKc_CCRK
cd07843	42-329	STKc_CDC2L1
cd07875	36-367	STKc_JNK1
cd07838	42-330	STKc_CDK4_6_like
cd07835	42-330	STKc_CDK1_CdkB_like
cd07842	41-329	STKc_CDK8_like
cd07845	42-329	STKc_CDK10
cd07833	41-330	STKc_CDKL
cd07866	41-329	STKc_BUR1
cd07836	42-329	STKc_Pho85
cd07860	42-329	STKc_CDK2_3
cd07839	41-329	STKc_CDK5
cd07831	42-329	STKc_MOK
cd07864	42-330	STKc_CDK12
cd07844	42-330	STKc_PCTAIRE_like
cd07861	42-330	STKc_CDK1_euk
cd07873	42-331	STKc_PCTAIRE1
cd07865	41-329	STKc_CDK9
cd07847	41-329	STKc_CDKL1_4
cd07871	42-330	STKc_PCTAIRE3
cd07863	41-330	STKc_CDK4
cd07846	41-329	STKc_CDKL2_3
cd05117	41-328	STKc_CAMK
cd07837	42-331	STKc_CdkB_plant
cd07870	42-330	STKc_PFTAIRE2
cd00180	48-328	PKc
cd14210	41-330	PKc_DYRK
cd14132	41-329	STKc_CK2_alpha
cd07872	42-331	STKc_PCTAIRE2
cd07862	41-329	STKc_CDK6
cd14133	42-330	PKc_DYRK_like
cd07848	41-328	STKc_CDKL5
cd14014	41-326	STKc_PknB_like
cd07869	36-330	STKc_PFTAIRE1
cd07867	48-330	STKc_CDC2L6
cd14003	41-329	STKc_AMPK-like
cd14084	35-330	STKc_Chk2
cd07868	48-330	STKc_CDK8
cd06606	41-330	STKc_MAPKKK
cd05122	42-330	PKc_STE
cd08215	41-330	STKc_Nek
cd14007	36-330	STKc_Aurora
cd14226	41-332	PKc_DYRK1
cd14225	41-330	PKc_DYRK4
cd14019	42-330	STKc_Cdc7
cd14134	40-330	PKc_CLK
cd13999	48-251	STKc_MAP3K-like
cd14212	42-330	PKc_YAK1
cd14009	48-329	STKc_ATG1_ULK_like
cd06614	42-331	STKc_PAK
cd14099	41-330	STKc_PLK
cd14135	41-330	STKc_PRP4
cd05123	48-329	STKc_AGC
cd14069	42-330	STKc_Chk1
cd14224	41-330	PKc_DYRK2_3
cd14008	48-330	STKc_LKB1_CaMKK
cd14091	42-333	STKc_RSK_C
cd14080	42-330	STKc_TSSK-like
cd14002	41-330	STKc_STK36
cd06623	48-335	PKc_MAPKK_plant_like
cd05579	48-331	STKc_MAST_like
cd14131	41-330	PKc_Mps1
cd14098	41-329	STKc_Rad53_Cds1
cd08217	42-330	STKc_Nek2
cd14119	48-330	STKc_LKB1
cd14096	41-330	STKc_RCK1-like
cd14081	48-330	STKc_BRSK1_2
cd14165	48-330	STKc_TSSK1_2-like
cd14663	41-329	STKc_SnRK3
cd14093	85-330	STKc_PhKG
cd14182	72-333	STKc_PhKG1
cd14082	48-329	STKc_PKD
cd06626	41-330	STKc_MEKK4
cd13993	41-325	STKc_Pat1_like
cd14046	44-327	STKc_EIF2AK4_GCN2_rpt2
cd14211	42-330	STKc_HIPK
cd14121	48-329	STKc_ULK3
cd14175	42-332	STKc_RSK1_C
cd06627	48-330	STKc_Cdc7_like
cd08529	42-330	STKc_FA2-like
cd06610	42-329	STKc_OSR1_SPAK
cd08530	41-328	STKc_CNK2-like
cd14079	48-330	STKc_AMPK_alpha
cd06624	48-330	STKc_ASK
cd14162	48-330	STKc_TSSK4-like
cd14006	48-329	STKc_MLCK-like
cd13996	44-239	STKc_EIF2AK
cd14229	42-330	STKc_HIPK3
cd05578	45-330	STKc_Yank1
cd06612	48-330	STKc_MST1_2
cd14213	41-330	PKc_CLK1_4
cd13994	48-330	STKc_HAL4_like
cd14086	41-332	STKc_CaMKII
cd14073	41-330	STKc_NUAK
cd06609	41-333	STKc_MST3_like
cd14228	42-330	STKc_HIPK1
cd14227	42-330	STKc_HIPK2
cd14136	41-330	STKc_SRPK
cd05581	46-329	STKc_PDK1
cd14214	41-330	PKc_CLK3
cd06620	44-338	PKc_Byr1_like
cd06605	48-333	PKc_MAPKK
cd06621	43-330	PKc_Pek1_like
cd14120	48-329	STKc_ULK1_2-like
cd14181	63-330	STKc_PhKG2
cd14166	45-330	STKc_CaMKI_gamma
cd06917	42-243	STKc_NAK1_like
cd06630	48-328	STKc_MEKK1
cd08224	41-325	STKc_Nek6_7
cd06625	48-329	STKc_MEKK3_like
cd00192	47-241	PTKc
cd14077	48-330	STKc_Kin1_2
cd08218	41-240	STKc_Nek1
cd14178	48-330	STKc_RSK3_C
cd06613	42-329	STKc_MAP4K3_like
cd14106	146-330	STKc_DRAK
cd14167	48-330	STKc_CaMKI_alpha
cd06608	37-330	STKc_myosinIII_N_like
cd14177	48-330	STKc_RSK4_C
cd06632	41-330	STKc_MEKK1_plant
cd14092	85-340	STKc_MSK_C
cd14176	42-330	STKc_RSK2_C
cd08223	41-330	STKc_Nek4
cd06629	41-330	STKc_Bck1_like
cd05611	118-329	STKc_Rim15_like
cd08219	41-245	STKc_Nek3
cd14161	41-327	STKc_NUAK2
cd14201	42-331	STKc_ULK2
cd05580	45-318	STKc_PKA_like
cd08225	41-254	STKc_Nek5
cd14087	41-330	STKc_PSKH1
cd13990	41-329	STKc_TLK
cd06607	41-332	STKc_TAO
cd14076	39-330	STKc_Kin4
cd14095	41-329	STKc_DCKL
cd14184	41-329	STKc_DCKL2
cd06635	42-366	STKc_TAO1
cd14194	87-330	STKc_DAPK1
cd14094	87-330	STKc_CASK
cd14083	48-329	STKc_CaMKI
cd08220	41-328	STKc_Nek8
cd08528	42-269	STKc_Nek10
cd14118	48-329	STKc_CAMKK
cd06647	41-331	STKc_PAK_I
cd06633	42-366	STKc_TAO3
cd06628	48-330	STKc_Byr2_like
cd14169	42-330	STKc_CaMKI_beta
cd13982	67-329	STKc_IRE1
cd06653	48-284	STKc_MEKK3_like_u1
cd14010	48-329	STKc_ULK4
cd06611	48-335	STKc_SLK_like
cd14164	42-240	STKc_TSSK6-like
cd14179	48-319	STKc_MSK1_C
cd14111	42-330	STKc_SPEG_rpt2
cd06634	42-367	STKc_TAO2
cd14114	41-330	STKc_Twitchin_like
cd05573	48-331	STKc_ROCK_NDR_like
cd06655	37-331	STKc_PAK2
cd14202	42-331	STKc_ULK1
cd14185	88-329	STKc_DCKL3
cd14097	42-330	STKc_STK33
cd06631	48-330	STKc_YSK4
cd14199	41-330	STKc_CaMKK2
cd06656	37-331	STKc_PAK3
cd08228	48-264	STKc_Nek6
cd14183	35-330	STKc_DCKL1
cd14058	48-245	STKc_TAK1
cd14196	87-330	STKc_DAPK2
cd14105	87-330	STKc_DAPK
cd06648	40-330	STKc_PAK_II
cd13997	41-328	PKc_Wee1_like
cd06654	37-331	STKc_PAK1
cd14163	48-239	STKc_TSSK3-like
cd14186	42-330	STKc_PLK4
cd06617	43-332	PKc_MKK3_6
cd14189	42-330	STKc_PLK3
cd06652	48-290	STKc_MEKK2
cd14089	46-329	STKc_MAPKAPK
cd14107	42-330	STKc_obscurin_rpt1
cd14188	41-330	STKc_PLK2
cd14116	36-330	STKc_Aurora-A
cd13985	41-321	STKc_GAK_like
cd14187	41-245	STKc_PLK1
cd14195	87-331	STKc_DAPK3
cd13979	45-249	STKc_Mos
cd14071	48-330	STKc_SIK
cd14052	41-328	PTKc_Wee1_fungi
cd14085	48-330	STKc_CaMKIV
cd06659	48-332	STKc_PAK6
cd13978	48-268	STKc_RIP
cd14066	48-243	STKc_IRAK
cd14198	135-330	STKc_DRAK2
cd05148	40-240	PTKc_Srm_Brk
cd14215	41-330	PKc_CLK2
cd05572	48-247	STKc_cGK
cd14038	48-246	STKc_IKK_beta
cd14104	48-332	STKc_Titin
cd13989	48-246	STKc_IKK
cd14216	41-330	STKc_SRPK1
cd14171	67-330	STKc_MAPKAPK5
cd14078	41-330	STKc_MELK
cd05034	48-249	PTKc_Src_like
cd14209	42-245	STKc_PKA
cd14200	48-330	STKc_CaMKK1
cd05038	45-240	PTKc_Jak_rpt2
cd14665	41-329	STKc_SnRK2-3
cd05598	42-331	STKc_LATS
cd14005	48-330	STKc_PIM
cd14197	149-330	STKc_DRAK1
cd05602	45-341	STKc_SGK1
cd14004	42-330	STKc_PASK
cd05063	43-256	PTKc_EphR_A2
cd05586	48-238	STKc_Sck1_like
cd06658	48-331	STKc_PAK5
cd14037	47-235	STKc_NAK_like
cd05585	145-332	STKc_YPK1_like
cd14110	42-330	STKc_obscurin_rpt2
cd14090	48-329	STKc_Mnk
cd14158	34-245	STKc_IRAK4
cd14049	42-239	STKc_EIF2AK1_HRI
cd14070	48-240	STKc_HUNK
cd06651	46-284	STKc_MEKK3
cd05039	48-240	PTKc_Csk_like
cd14103	48-330	STKc_MLCK
cd08221	134-330	STKc_Nek9
cd14048	45-239	STKc_EIF2AK3_PERK
cd06642	42-249	STKc_STK25
cd05609	48-247	STKc_MAST
cd14173	44-330	STKc_Mnk2
cd08222	149-330	STKc_Nek11
cd06640	42-257	STKc_MST4
cd06636	45-330	STKc_MAP4K4_6_N
cd14060	49-247	STKc_MLTK
cd05584	45-247	STKc_p70S6K
cd05612	48-248	STKc_PRKX_like
cd05072	48-247	PTKc_Lyn
cd13987	48-327	STKc_SBK1
cd05065	46-243	PTKc_EphR_B
cd13986	41-327	STKc_16
cd14168	32-330	STKc_CaMKI_delta
cd13995	47-330	STKc_MAP3K8
cd05599	45-245	STKc_NDR_like
cd14061	48-247	STKc_MLK
cd05570	123-329	STKc_PKC
cd13983	41-242	STKc_WNK
cd05082	45-240	PTKc_Csk
cd05068	45-256	PTKc_Frk_like
cd14205	45-240	PTKc_Jak2_rpt2
cd05073	48-247	PTKc_Hck
cd13991	39-240	STKc_NIK
cd06643	48-343	STKc_SLK
cd14108	46-257	STKc_SPEG_rpt1
cd14074	48-330	STKc_SNRK
cd14016	41-189	STKc_CK1
cd14180	48-323	STKc_MSK2_C
cd14039	48-243	STKc_IKK_alpha
cd06619	44-342	PKc_MKK5
cd14218	41-330	STKc_SRPK3
cd06641	42-243	STKc_MST3
cd14193	46-330	STKc_MLCK4
cd14047	42-240	STKc_EIF2AK2_PKR
cd06616	48-254	PKc_MKK4
cd14109	86-330	PK_Unc-89_rpt1
cd14117	48-331	STKc_Aurora-B_like
cd06644	48-343	STKc_STK10
cd14203	66-254	PTKc_Src_Fyn_like
cd14059	48-240	STKc_MAP3K12_13
cd14190	48-258	STKc_MLCK2
cd05055	48-240	PTKc_PDGFR
cd06657	48-337	STKc_PAK4
cd06615	148-246	PKc_MEK
cd14075	48-240	STKc_NIM1
cd05041	46-240	PTKc_Fes_like
cd05071	48-254	PTKc_Src
cd06622	45-336	PKc_PBS2_like
cd05033	43-243	PTKc_EphR
cd14036	48-235	STKc_GAK
cd06637	45-330	STKc_TNIK
cd08229	48-267	STKc_Nek7
cd05112	43-240	PTKc_Itk
cd05060	48-240	PTKc_Syk_like
cd14053	68-278	STKc_ACVR2
cd14072	41-323	STKc_MARK
cd14662	41-329	STKc_SnRK2
cd14192	88-330	STKc_MLCK3
cd14174	46-331	STKc_Mnk1
cd14050	42-241	PKc_Myt1
cd14088	88-330	STKc_CaMK_like
cd06645	36-332	STKc_MAP4K3
cd14011	87-331	PK_SCY1_like
cd05066	48-243	PTKc_EphR_A
cd05587	110-247	STKc_cPKC
cd05059	43-240	PTKc_Tec_like
cd05577	145-254	STKc_GRK
cd06646	42-330	STKc_MAP4K5
cd05595	129-368	STKc_PKB_beta
cd06650	150-332	PKc_MEK1
cd05605	149-245	STKc_GRK4_like
cd05069	48-247	PTKc_Yes
cd05070	45-257	PTKc_Fyn
cd05582	84-258	STKc_RSK_N
cd05081	44-251	PTKc_Jak3_rpt2
cd05067	48-247	PTKc_Lck_Blk
cd05603	48-258	STKc_SGK2
cd14170	46-341	STKc_MAPKAPK2
cd05084	46-240	PTKc_Fes
cd05079	48-240	PTKc_Jak1_rpt2
cd14146	48-240	STKc_MLK4
cd14001	69-240	PKc_TOPK
cd06638	45-330	STKc_myosinIIIA_N
cd14221	48-239	STKc_LIMK1
cd05604	45-258	STKc_SGK3
cd14062	48-254	STKc_Raf
cd05575	149-341	STKc_SGK
cd05102	84-240	PTKc_VEGFR3
cd05616	110-248	STKc_cPKC_beta
cd05632	42-248	STKc_GRK5
cd05097	15-240	PTKc_DDR_like
cd14145	46-247	STKc_MLK1
cd05085	46-240	PTKc_Fer
cd14172	46-330	STKc_MAPKAPK3
cd13977	41-318	STKc_PDIK1L
cd14041	41-330	STKc_TLK2
cd05107	107-240	PTKc_PDGFR_beta
cd05083	48-240	PTKc_Chk
cd05103	122-249	PTKc_VEGFR2
cd05040	48-240	PTKc_Ack_like
cd05630	42-245	STKc_GRK6
cd05058	46-258	PTKc_Met_Ron
cd05053	41-240	PTKc_FGFR
cd14148	48-240	STKc_MLK2
cd14000	75-259	STKc_LRRK
cd05105	135-240	PTKc_PDGFR_alpha
cd14113	42-240	STKc_Trio_C
cd05608	42-245	STKc_GRK1
cd05057	44-240	PTKc_EGFR_like
cd14040	41-330	STKc_TLK1
cd05589	153-361	STKc_PKN
cd14115	48-329	STKc_Kalirin_C
cd14220	48-276	STKc_BMPR1a
cd05600	42-247	STKc_Sid2p_like
cd05054	48-240	PTKc_VEGFR
cd14217	41-330	STKc_SRPK2
cd14065	48-246	PKc_LIMK_like
cd14033	48-243	STKc_WNK4
cd14154	48-239	STKc_LIMK
cd05593	42-359	STKc_PKB_gamma
cd06639	45-257	STKc_myosinIIIB_N
cd14664	48-244	STK_BAK1_like
cd05626	42-245	STKc_LATS2
cd05590	123-347	STKc_nPKC_eta
cd05032	43-240	PTKc_InsR_like
cd05583	48-329	STKc_MSK_N
cd05571	130-331	STKc_PKB
cd14144	46-278	STKc_BMPR1
cd05601	48-329	STKc_CRIK
cd05080	44-240	PTKc_Tyk2_rpt2
cd05619	145-346	STKc_nPKC_theta
cd05621	42-239	STKc_ROCK2
cd05614	45-331	STKc_MSK2_N
cd05114	43-240	PTKc_Tec_Rlk
cd05606	123-254	STKc_beta_ARK
cd14054	46-248	STKc_BMPR2_AMHR2
cd05607	143-245	STKc_GRK7
cd06618	117-343	PKc_MKK7
cd14156	54-246	PKc_LIMK_like_unk
cd06649	150-246	PKc_MEK2
cd14207	128-240	PTKc_VEGFR1
cd05044	47-257	PTKc_c-ros
cd13998	48-240	STKc_TGFbR-like
cd05625	42-245	STKc_LATS1
cd13988	48-265	STKc_TBK1
cd08216	54-241	PK_STRAD
cd05051	61-240	PTKc_DDR
cd14112	44-330	STKc_Unc-89_rpt2
cd14100	36-239	STKc_PIM1
cd05092	48-240	PTKc_TrkA
cd14191	48-330	STKc_MLCK1
cd05098	48-247	PTKc_FGFR1
cd05095	14-240	PTKc_DDR2
cd14056	48-239	STKc_TGFbR_I
cd14027	51-269	STKc_RIP1
cd05113	43-240	PTKc_Btk_Bmx
cd14155	85-240	PKc_TESK
cd14012	82-269	PK_eIF2AK_GCN2_rpt1
cd14159	48-242	STKc_IRAK1
cd05620	118-331	STKc_nPKC_delta
cd05615	123-248	STKc_cPKC_alpha
cd05613	45-360	STKc_MSK1_N
cd05046	48-240	PTK_CCK4
cd05628	42-245	STKc_NDR1
cd14101	42-331	STKc_PIM2
cd05115	48-250	PTKc_Zap-70
cd14025	48-261	STKc_RIP4_like
cd05627	42-357	STKc_NDR2
cd05596	42-239	STKc_ROCK
cd14068	47-240	STKc_LRRK2
cd05116	48-240	PTKc_Syk
cd05056	48-240	PTKc_FAK
cd05099	48-247	PTKc_FGFR4
cd14150	45-291	STKc_A-Raf
cd05633	121-254	STKc_GRK3
cd05592	149-328	STKc_nPKC_theta_like
cd05631	145-245	STKc_GRK4
cd14223	121-260	STKc_GRK2
cd05622	42-239	STKc_ROCK1
cd05043	135-240	PTK_Ryk
cd05610	48-330	STKc_MASTL
cd14055	68-240	STKc_TGFbR2_like
cd14222	48-239	STKc_LIMK2
cd14017	41-189	STKc_TTBK
cd14031	48-241	STKc_WNK3
cd05624	45-239	STKc_MRCK_beta
cd05045	48-247	PTKc_RET
cd05101	48-317	PTKc_FGFR2
cd05618	129-319	STKc_aPKC_iota
cd14064	48-240	PKc_TNNI3K
cd05106	135-247	PTKc_CSF-1R
cd05104	146-247	PTKc_Kit
cd05594	42-249	STKc_PKB_alpha
cd05574	48-329	STKc_phototropin_like
cd05100	133-247	PTKc_FGFR3
cd14219	48-326	STKc_BMPR1b
cd05096	48-240	PTKc_DDR1
cd14026	45-245	STKc_RIP2
cd14141	51-240	STKc_ACVR2a
cd05048	45-240	PTKc_Ror
cd05075	48-257	PTKc_Axl
cd05108	42-240	PTKc_EGFR
cd14147	46-247	STKc_MLK3
cd05588	123-245	STKc_aPKC
cd14140	68-278	STKc_ACVR2b
cd05629	42-245	STKc_NDR_like_fungal
cd05617	129-245	STKc_aPKC_zeta
cd14102	146-239	STKc_PIM3
cd05049	48-240	PTKc_Trk
cd13974	133-327	STKc_SHIK
cd14013	149-330	STKc_SNT7_plant
cd14020	150-330	STKc_KIS
cd14032	48-241	STKc_WNK2_like
cd05109	149-240	PTKc_HER2
cd05052	46-238	PTKc_Abl
cd05591	123-332	STKc_nPKC_epsilon
cd05047	48-240	PTKc_Tie
cd14149	48-276	STKc_C-Raf
cd14042	64-238	PK_GC-A_B
cd14067	148-272	STKc_LRRK1
cd14151	46-259	STKc_B-Raf
cd14142	43-247	STKc_ACVR1_ALK1
cd14143	48-273	STKc_TGFbR1_ACVR1b_ACVR1c
cd05623	45-258	STKc_MRCK_alpha
cd13980	148-333	STKc_Vps15
TIGR03724	157-197	arch_bud32
COG3642	94-197	Bud32
smart00220	42-330	S_TKc
pfam00069	42-330	Pkinase
PTZ00024	36-348	PTZ00024
PLN00009	41-331	PLN00009
PTZ00036	48-336	PTZ00036
COG0515	42-340	SPS1
smart00221	45-241	STYKc
smart00219	45-241	TyrKc
pfam07714	48-257	Pkinase_Tyr
PTZ00284	26-334	PTZ00284
PTZ00263	48-329	PTZ00263
PHA03209	85-328	PHA03209
PLN00034	48-332	PLN00034
PRK13184	41-246	pknD
PTZ00426	45-276	PTZ00426
PHA03390	116-330	pk1
PHA03210	88-328	PHA03210
PHA03211	78-332	PHA03211
PHA03212	42-341	PHA03212
PTZ00267	146-331	PTZ00267
PTZ00266	88-254	PTZ00266
PHA03207	38-245	PHA03207
PTZ00283	128-258	PTZ00283
TIGR03903	67-247	TOMM_kin_cyc

Ontology Information

   

HPRD ID	16004
Molecular Class	Serine/threonine kinase
Molecular Function	Transcription regulator activity (GO:0030528)
Biological Process	Regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism (GO:0019219)

SNP Information

View SNP Geneview Report