Search results:
General Information
| Gene_Symbol | Gene_ID | Gene_Name | Chromosome | Alias |
|---|---|---|---|---|
| MAP2K7 | 5609 | mitogen-activated protein kinase kinase 7 | 19 | MKK7, Jnkk2 |
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 23027623 | 2012 | Cell line : - Source : Twin Cities Metropolitan Area or a seven-county area of Utah or enrolled in the Kaiser Permanente Medical Care Program of Northern California (KPMCP). Sample Type : Population-based case-control studies No. of Sample : Colon 1555 cases, 1956 controls, rectal 754 cases, 959 controls Stage : - | TagSNP selection and genotyping | Polymorhpism | - | - |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | Mitogen-activated protein kinase cascade / Kinase kinases |
| Description | The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically activates MAPK8/JNK1 and MAPK9/JNK2, and this kinase itself is phosphorylated and activated by MAP kinase kinase kinases including MAP3K1/MEKK1, MAP3K2/MEKK2,MAP3K3/MEKK5, and MAP4K2/GCK. This kinase is involved in the signal transduction mediating the cell responses to proinflammatory cytokines, and environmental stresses. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014] |
| Chromosome | 19 |
| Location | 19p13.3-p1 |
| Start | 7968665 |
| End | 7979363 |
| Strand | + |
| Gene Sequence | Download Select all |
| Length | 10699 |
| OMIM ID | 603014 |
| HGNC ID | HGNC:6847 |
| Unigene ID | Hs.531754 |
| Ensembl ID | ENSG00000076984 |
| PharmGKB ID | PA284 |
mRNA Information
| mRNA ID | ?NM_001297555.1 |
|---|---|
| Exon | join(1..289,2029..2076,5976..6117,6284..6350,6481..6594, 6674..6793,6917..7024,7201..7380,7471..7551,7657..7799, 8370..8415,8518..10704) | mRNA Sequence | Download Select all |
| Length | 3525 |
Protein Information
| Protein ID | NP_001284484.1 |
|---|---|
| Protein Name | mitogen-activated protein kinase kinase 7 |
| Molecular Wt. (Da) | 0 |
| Protein Sequence | Download Select all |
| Length | 419 |
| Uniprot ID | Q13620 |
| Ensembl Protein ID | ENSP00000360373 |
Post-translational Modification Information (Source : HPRD)
| Residue | Type | site |
|---|---|---|
| S | Phosphorylation | 35 |
| S | Phosphorylation | 35 |
| S | Phosphorylation | 86 |
| S | Phosphorylation | 89 |
| S | Phosphorylation | 86 |
| S | Phosphorylation | 89 |
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
| Interactant Gene ID (Source: HPRD) | Gene Symbol | HPRD ID | Ref Seq ID | Technique | References |
|---|---|---|---|---|---|
| 4217 | MAP3K5 | 3904 | NP_005914.1 | in vitro;in vivo | 11959862 |
| 4296 | MAP3K11 | 2502 | NP_002410.1 | in vitro;in vivo | 10187804 |
| 4616 | GADD45B | 5382 | NP_056490.2 | in vitro;in vivo | 14743220 |
| 5599 | MAPK8 | 3100 | NP_620637.1 | in vitro;in vivo | 92 070 921 106 206 700 000 000 |
| 5601 | MAPK9 | 4206 | NP_002743.3 | in vitro;in vivo | 11062067 |
| 7786 | MAP3K12 | 2709 | NP_006292.2 | in vitro;in vivo | 10187804 |
Pathway Information
| Pathway Name | Pathway ID |
|---|---|
| Epstein-Barr virus infection | hsa05169 |
| ErbB signaling pathway | hsa04012 |
| Fc epsilon RI signaling pathway | hsa04664 |
| GnRH signaling pathway | hsa04912 |
| Influenza A | hsa05164 |
| MAPK signaling pathway | hsa04010 |
| Neurotrophin signaling pathway | hsa04722 |
| Osteoclast differentiation | hsa04380 |
| Protein processing in endoplasmic reticulum | hsa04141 |
| T cell receptor signaling pathway | hsa04660 |
| TNF signaling pathway | hsa04668 |
| Toll-like receptor signaling pathway | hsa04620 |
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| cd06618 | 104-400 | PKc_MKK7 |
| cl21453 | 104-400 | PKc_like superfamily |
| cd06605 | 118-385 | PKc_MAPKK |
| cd06616 | 113-398 | PKc_MKK4 |
| cd06617 | 119-395 | PKc_MKK3_6 |
| cd06622 | 118-398 | PKc_PBS2_like |
| cd06623 | 118-384 | PKc_MAPKK_plant_like |
| cd06615 | 119-398 | PKc_MEK |
| cd06620 | 119-393 | PKc_Byr1_like |
| cd06621 | 118-397 | PKc_Pek1_like |
| cd05122 | 119-380 | PKc_STE |
| cd06650 | 118-394 | PKc_MEK1 |
| cd06619 | 119-392 | PKc_MKK5 |
| cd06606 | 124-380 | STKc_MAPKKK |
| cd06649 | 118-416 | PKc_MEK2 |
| cd06609 | 118-383 | STKc_MST3_like |
| cd06612 | 120-380 | STKc_MST1_2 |
| cd06613 | 119-380 | STKc_MAP4K3_like |
| cd14014 | 127-370 | STKc_PknB_like |
| cd06610 | 118-380 | STKc_OSR1_SPAK |
| cd08215 | 121-380 | STKc_Nek |
| cd14007 | 127-381 | STKc_Aurora |
| cd06608 | 125-380 | STKc_myosinIII_N_like |
| cd06627 | 123-380 | STKc_Cdc7_like |
| cd00180 | 127-378 | PKc |
| cd06626 | 127-380 | STKc_MEKK4 |
| cd06614 | 120-381 | STKc_PAK |
| cd06642 | 123-383 | STKc_STK25 |
| cd14003 | 127-377 | STKc_AMPK-like |
| cd06611 | 121-382 | STKc_SLK_like |
| cd14002 | 123-380 | STKc_STK36 |
| cd13999 | 126-376 | STKc_MAP3K-like |
| cd06917 | 126-383 | STKc_NAK1_like |
| cd06641 | 120-382 | STKc_MST3 |
| cd06644 | 121-385 | STKc_STK10 |
| cd06640 | 123-383 | STKc_MST4 |
| cd06632 | 126-380 | STKc_MEKK1_plant |
| cd06643 | 121-380 | STKc_SLK |
| cd05117 | 127-379 | STKc_CAMK |
| cd05123 | 127-368 | STKc_AGC |
| cd05118 | 121-380 | STKc_CMGC |
| cd06607 | 121-382 | STKc_TAO |
| cd06648 | 119-381 | STKc_PAK_II |
| cd14008 | 127-380 | STKc_LKB1_CaMKK |
| cd08529 | 119-375 | STKc_FA2-like |
| cd06625 | 126-380 | STKc_MEKK3_like |
| cd06638 | 126-380 | STKc_myosinIIIA_N |
| cd06639 | 113-381 | STKc_myosinIIIB_N |
| cd06636 | 126-380 | STKc_MAP4K4_6_N |
| cd06637 | 126-405 | STKc_TNIK |
| cd08217 | 119-380 | STKc_Nek2 |
| cd06645 | 119-382 | STKc_MAP4K3 |
| cd14010 | 125-379 | STKc_ULK4 |
| cd06633 | 122-388 | STKc_TAO3 |
| cd07833 | 118-379 | STKc_CDKL |
| cd13997 | 119-378 | PKc_Wee1_like |
| cd06631 | 124-380 | STKc_YSK4 |
| cd06628 | 126-380 | STKc_Byr2_like |
| cd05579 | 128-397 | STKc_MAST_like |
| cd06635 | 122-398 | STKc_TAO1 |
| cd06646 | 118-380 | STKc_MAP4K5 |
| cd06629 | 124-380 | STKc_Bck1_like |
| cd05578 | 127-380 | STKc_Yank1 |
| cd06647 | 125-381 | STKc_PAK_I |
| cd06634 | 122-388 | STKc_TAO2 |
| cd00192 | 127-377 | PTKc |
| cd06630 | 124-377 | STKc_MEKK1 |
| cd07830 | 125-379 | STKc_MAK_like |
| cd08224 | 125-369 | STKc_Nek6_7 |
| cd08530 | 119-378 | STKc_CNK2-like |
| cd06659 | 120-380 | STKc_PAK6 |
| cd06624 | 112-380 | STKc_ASK |
| cd14080 | 126-380 | STKc_TSSK-like |
| cd05611 | 123-336 | STKc_Rim15_like |
| cd14073 | 111-377 | STKc_NUAK |
| cd14121 | 126-379 | STKc_ULK3 |
| cd13996 | 112-376 | STKc_EIF2AK |
| cd14663 | 126-379 | STKc_SnRK3 |
| cd06654 | 125-381 | STKc_PAK1 |
| cd05570 | 126-368 | STKc_PKC |
| cd05581 | 118-382 | STKc_PDK1 |
| cd06655 | 125-381 | STKc_PAK2 |
| cd13983 | 125-380 | STKc_WNK |
| cd06656 | 125-381 | STKc_PAK3 |
| cd08228 | 170-369 | STKc_Nek6 |
| cd14046 | 112-377 | STKc_EIF2AK4_GCN2_rpt2 |
| cd07829 | 120-321 | STKc_CDK_like |
| cd13979 | 120-369 | STKc_Mos |
| cd08528 | 123-369 | STKc_Nek10 |
| cd07832 | 123-336 | STKc_CCRK |
| cd05572 | 127-338 | STKc_cGK |
| cd06653 | 126-380 | STKc_MEKK3_like_u1 |
| cd14098 | 126-377 | STKc_Rad53_Cds1 |
| cd14050 | 121-377 | PKc_Myt1 |
| cd14009 | 127-323 | STKc_ATG1_ULK_like |
| cd06658 | 120-381 | STKc_PAK5 |
| cd13993 | 126-368 | STKc_Pat1_like |
| cd06657 | 120-382 | STKc_PAK4 |
| cd05583 | 126-381 | STKc_MSK_N |
| cd14066 | 126-333 | STKc_IRAK |
| cd14059 | 126-377 | STKc_MAP3K12_13 |
| cd06652 | 126-380 | STKc_MEKK2 |
| cd14099 | 126-380 | STKc_PLK |
| cd14081 | 126-380 | STKc_BRSK1_2 |
| cd05059 | 119-376 | PTKc_Tec_like |
| cd13985 | 125-376 | STKc_GAK_like |
| cd07847 | 121-379 | STKc_CDKL1_4 |
| cd14005 | 124-378 | STKc_PIM |
| cd05604 | 126-412 | STKc_SGK3 |
| cd05573 | 118-381 | STKc_ROCK_NDR_like |
| cd05577 | 126-381 | STKc_GRK |
| cd14084 | 126-380 | STKc_Chk2 |
| cd14091 | 119-398 | STKc_RSK_C |
| cd14052 | 119-378 | PTKc_Wee1_fungi |
| cd14106 | 117-380 | STKc_DRAK |
| cd08229 | 125-369 | STKc_Nek7 |
| cd08216 | 138-381 | PK_STRAD |
| cd13978 | 126-371 | STKc_RIP |
| cd08223 | 126-380 | STKc_Nek4 |
| cd05601 | 118-379 | STKc_CRIK |
| cd13994 | 126-380 | STKc_HAL4_like |
| cd05607 | 126-339 | STKc_GRK7 |
| cd14164 | 123-380 | STKc_TSSK6-like |
| cd06651 | 126-379 | STKc_MEKK3 |
| cd14047 | 119-377 | STKc_EIF2AK2_PKR |
| cd14082 | 126-322 | STKc_PKD |
| cd14161 | 121-341 | STKc_NUAK2 |
| cd14118 | 226-380 | STKc_CAMKK |
| cd05585 | 126-404 | STKc_YPK1_like |
| cd08218 | 123-380 | STKc_Nek1 |
| cd05580 | 118-368 | STKc_PKA_like |
| cd14181 | 126-379 | STKc_PhKG2 |
| cd07846 | 121-379 | STKc_CDKL2_3 |
| cd14131 | 120-379 | PKc_Mps1 |
| cd14137 | 127-321 | STKc_GSK3 |
| cd05612 | 119-397 | STKc_PRKX_like |
| cd08222 | 126-380 | STKc_Nek11 |
| cd05574 | 119-368 | STKc_phototropin_like |
| cd05586 | 126-322 | STKc_Sck1_like |
| cd14162 | 126-378 | STKc_TSSK4-like |
| cd05614 | 119-381 | STKc_MSK2_N |
| cd05599 | 118-322 | STKc_NDR_like |
| cd13987 | 126-325 | STKc_SBK1 |
| cd14133 | 123-380 | PKc_DYRK_like |
| cd05608 | 126-368 | STKc_GRK1 |
| cd05571 | 126-368 | STKc_PKB |
| cd14058 | 126-369 | STKc_TAK1 |
| cd14210 | 113-380 | PKc_DYRK |
| cd08220 | 119-380 | STKc_Nek8 |
| cd08221 | 157-380 | STKc_Nek9 |
| cd14078 | 125-380 | STKc_MELK |
| cd05112 | 125-375 | PTKc_Itk |
| cd14074 | 117-380 | STKc_SNRK |
| cd05582 | 126-322 | STKc_RSK_N |
| cd08225 | 123-380 | STKc_Nek5 |
| cd08219 | 119-378 | STKc_Nek3 |
| cd14116 | 114-380 | STKc_Aurora-A |
| cd05633 | 126-381 | STKc_GRK3 |
| cd08226 | 121-381 | PK_STRAD_beta |
| cd14004 | 123-377 | STKc_PASK |
| cd14090 | 126-380 | STKc_Mnk |
| cd14146 | 126-377 | STKc_MLK4 |
| cd05613 | 119-368 | STKc_MSK1_N |
| cd05060 | 124-383 | PTKc_Syk_like |
| cd14093 | 140-322 | STKc_PhKG |
| cd05594 | 112-404 | STKc_PKB_alpha |
| cd05057 | 120-376 | PTKc_EGFR_like |
| cd14209 | 119-368 | STKc_PKA |
| cd05108 | 126-375 | PTKc_EGFR |
| cd14163 | 126-380 | STKc_TSSK3-like |
| cd05084 | 125-374 | PTKc_Fes |
| cd14182 | 126-383 | STKc_PhKG1 |
| cd05619 | 126-344 | STKc_nPKC_theta |
| cd05609 | 119-339 | STKc_MAST |
| cd14079 | 123-377 | STKc_AMPK_alpha |
| cd05592 | 126-340 | STKc_nPKC_theta_like |
| cd07838 | 121-379 | STKc_CDK4_6_like |
| cd07834 | 127-321 | STKc_MAPK |
| cd14165 | 122-380 | STKc_TSSK1_2-like |
| cd05600 | 118-382 | STKc_Sid2p_like |
| cd07856 | 122-340 | STKc_Sty1_Hog1 |
| cd05032 | 118-376 | PTKc_InsR_like |
| cd14061 | 126-376 | STKc_MLK |
| cd14176 | 166-403 | STKc_RSK2_C |
| cd14006 | 127-377 | STKc_MLCK-like |
| cd05602 | 114-368 | STKc_SGK1 |
| cd14223 | 126-368 | STKc_GRK2 |
| cd05624 | 74-417 | STKc_MRCK_beta |
| cd05610 | 129-379 | STKc_MASTL |
| cd05041 | 126-324 | PTKc_Fes_like |
| cd14147 | 126-377 | STKc_MLK3 |
| cd14174 | 126-381 | STKc_Mnk1 |
| cd14166 | 126-380 | STKc_CaMKI_gamma |
| cd14198 | 125-380 | STKc_DRAK2 |
| cd14169 | 117-390 | STKc_CaMKI_beta |
| cd07848 | 118-341 | STKc_CDKL5 |
| cd14148 | 126-376 | STKc_MLK2 |
| cd05630 | 126-368 | STKc_GRK6 |
| cd14001 | 147-376 | PKc_TOPK |
| cd14027 | 128-371 | STKc_RIP1 |
| cd07835 | 120-321 | STKc_CDK1_CdkB_like |
| cd14191 | 118-380 | STKc_MLCK1 |
| cd14101 | 211-381 | STKc_PIM2 |
| cd14070 | 177-369 | STKc_HUNK |
| cd05623 | 119-322 | STKc_MRCK_alpha |
| cd14145 | 126-377 | STKc_MLK1 |
| cd05595 | 126-379 | STKc_PKB_beta |
| cd05593 | 117-379 | STKc_PKB_gamma |
| cd05115 | 125-374 | PTKc_Zap-70 |
| cd05068 | 114-379 | PTKc_Frk_like |
| cd14178 | 125-386 | STKc_RSK3_C |
| cd13990 | 126-379 | STKc_TLK |
| cd14120 | 126-323 | STKc_ULK1_2-like |
| cd07860 | 121-321 | STKc_CDK2_3 |
| cd14175 | 166-386 | STKc_RSK1_C |
| cd07851 | 121-321 | STKc_p38 |
| cd07841 | 120-381 | STKc_CDK7 |
| cd14077 | 126-322 | STKc_Kin1_2 |
| cd07845 | 117-323 | STKc_CDK10 |
| cd14119 | 145-378 | STKc_LKB1 |
| cd05631 | 126-368 | STKc_GRK4 |
| cd14167 | 116-380 | STKc_CaMKI_alpha |
| cd07843 | 129-338 | STKc_CDC2L1 |
| cd14085 | 125-381 | STKc_CaMKIV |
| cd05618 | 117-368 | STKc_aPKC_iota |
| cd05603 | 126-368 | STKc_SGK2 |
| cd05627 | 117-344 | STKc_NDR2 |
| cd05116 | 124-371 | PTKc_Syk |
| cd05617 | 117-368 | STKc_aPKC_zeta |
| cd14094 | 177-381 | STKc_CASK |
| cd05606 | 126-368 | STKc_beta_ARK |
| cd14201 | 126-381 | STKc_ULK2 |
| cd14185 | 126-379 | STKc_DCKL3 |
| cd14062 | 232-376 | STKc_Raf |
| cd14069 | 226-340 | STKc_Chk1 |
| cd05590 | 126-368 | STKc_nPKC_eta |
| cd05584 | 120-322 | STKc_p70S6K |
| cd14064 | 126-326 | PKc_TNNI3K |
| cd05033 | 124-375 | PTKc_EphR |
| cd14117 | 117-344 | STKc_Aurora-B_like |
| cd05597 | 119-322 | STKc_DMPK_like |
| cd14202 | 126-380 | STKc_ULK1 |
| cd14017 | 123-377 | STKc_TTBK |
| cd14092 | 126-411 | STKc_MSK_C |
| cd14083 | 126-310 | STKc_CaMKI |
| cd05628 | 119-366 | STKc_NDR1 |
| cd14665 | 125-324 | STKc_SnRK2-3 |
| cd14179 | 111-376 | STKc_MSK1_C |
| cd08227 | 138-382 | PK_STRAD_alpha |
| cd05632 | 126-368 | STKc_GRK5 |
| cd14012 | 223-379 | PK_eIF2AK_GCN2_rpt1 |
| cd05034 | 126-374 | PTKc_Src_like |
| cd07840 | 121-324 | STKc_CDK9_like |
| cd14199 | 226-370 | STKc_CaMKK2 |
| cd14065 | 126-377 | PKc_LIMK_like |
| cd05067 | 118-380 | PTKc_Lck_Blk |
| cd07852 | 126-321 | STKc_MAPK15-like |
| cd14089 | 126-310 | STKc_MAPKAPK |
| cd05113 | 119-375 | PTKc_Btk_Bmx |
| cd14105 | 117-380 | STKc_DAPK |
| cd05620 | 126-340 | STKc_nPKC_delta |
| cd14195 | 117-381 | STKc_DAPK3 |
| cd05039 | 117-376 | PTKc_Csk_like |
| cd14072 | 126-322 | STKc_MARK |
| cd14186 | 119-380 | STKc_PLK4 |
| cd13989 | 126-340 | STKc_IKK |
| cd14177 | 116-403 | STKc_RSK4_C |
| cd07837 | 121-321 | STKc_CdkB_plant |
| cd05044 | 126-376 | PTKc_c-ros |
| cd05114 | 118-337 | PTKc_Tec_Rlk |
| cd14037 | 112-379 | STKc_NAK_like |
| cd07831 | 123-324 | STKc_MOK |
| cd05616 | 119-387 | STKc_cPKC_beta |
| cd05621 | 111-322 | STKc_ROCK2 |
| cd14048 | 117-377 | STKc_EIF2AK3_PERK |
| cd14221 | 126-374 | STKc_LIMK1 |
| cd05575 | 127-368 | STKc_SGK |
| cd05109 | 119-376 | PTKc_HER2 |
| cd14662 | 121-324 | STKc_SnRK2 |
| cd05591 | 126-387 | STKc_nPKC_epsilon |
| cd07861 | 119-317 | STKc_CDK1_euk |
| cd13988 | 126-341 | STKc_TBK1 |
| cd05052 | 126-379 | PTKc_Abl |
| cd14060 | 127-375 | STKc_MLTK |
| cd14033 | 125-379 | STKc_WNK4 |
| cd13986 | 213-377 | STKc_16 |
| cd05072 | 125-374 | PTKc_Lyn |
| cd14173 | 226-380 | STKc_Mnk2 |
| cd05065 | 126-375 | PTKc_EphR_B |
| cd05622 | 112-403 | STKc_ROCK1 |
| cd05066 | 126-375 | PTKc_EphR_A |
| cd14096 | 123-380 | STKc_RCK1-like |
| cd07839 | 121-321 | STKc_CDK5 |
| cd05598 | 126-322 | STKc_LATS |
| cd14158 | 126-318 | STKc_IRAK4 |
| cd14203 | 125-381 | PTKc_Src_Fyn_like |
| cd14200 | 226-368 | STKc_CaMKK1 |
| cd14664 | 126-321 | STK_BAK1_like |
| cd14188 | 126-379 | STKc_PLK2 |
| cd05596 | 117-322 | STKc_ROCK |
| cd14103 | 126-380 | STKc_MLCK |
| cd05036 | 146-377 | PTKc_ALK_LTK |
| cd14071 | 126-377 | STKc_SIK |
| cd14151 | 228-375 | STKc_B-Raf |
| cd14107 | 125-377 | STKc_obscurin_rpt1 |
| cd14189 | 126-379 | STKc_PLK3 |
| cd14095 | 126-321 | STKc_DCKL |
| cd05626 | 126-379 | STKc_LATS2 |
| cd14196 | 116-380 | STKc_DAPK2 |
| cd14197 | 125-322 | STKc_DRAK1 |
| cd14225 | 113-324 | PKc_DYRK4 |
| cd14205 | 120-374 | PTKc_Jak2_rpt2 |
| cd14075 | 124-323 | STKc_NIM1 |
| cd07862 | 121-315 | STKc_CDK6 |
| cd05083 | 187-376 | PTKc_Chk |
| cd14156 | 126-376 | PKc_LIMK_like_unk |
| cd05587 | 126-405 | STKc_cPKC |
| cd05615 | 116-387 | STKc_cPKC_alpha |
| cd13992 | 126-370 | PK_GC |
| cd05047 | 126-375 | PTKc_Tie |
| cd14031 | 125-379 | STKc_WNK3 |
| cd05605 | 238-368 | STKc_GRK4_like |
| cd07870 | 122-335 | STKc_PFTAIRE2 |
| cd14154 | 126-379 | STKc_LIMK |
| cd05056 | 119-374 | PTKc_FAK |
| cd07836 | 120-318 | STKc_Pho85 |
| cd14100 | 211-380 | STKc_PIM1 |
| cd07871 | 123-336 | STKc_PCTAIRE3 |
| cd07877 | 113-343 | STKc_p38alpha |
| cd14150 | 232-375 | STKc_A-Raf |
| cd14180 | 126-381 | STKc_MSK2_C |
| cd14019 | 218-379 | STKc_Cdc7 |
| cd05073 | 125-322 | PTKc_Hck |
| cd05103 | 226-377 | PTKc_VEGFR2 |
| cd07863 | 121-380 | STKc_CDK4 |
| cd07880 | 122-323 | STKc_p38gamma |
| cd13991 | 113-342 | STKc_NIK |
| cd05110 | 119-374 | PTKc_HER4 |
| cd05071 | 125-385 | PTKc_Src |
| cd14187 | 123-379 | STKc_PLK1 |
| cd14194 | 124-380 | STKc_DAPK1 |
| cd13968 | 126-263 | PKc_like |
| cd14114 | 123-380 | STKc_Twitchin_like |
| cd14149 | 113-381 | STKc_C-Raf |
| cd05085 | 124-374 | PTKc_Fer |
| cd14032 | 125-379 | STKc_WNK2_like |
| cd14168 | 113-380 | STKc_CaMKI_delta |
| cd14207 | 213-376 | PTKc_VEGFR1 |
| cd14000 | 126-369 | STKc_LRRK |
| cd14040 | 172-372 | STKc_TLK1 |
| cd14172 | 126-322 | STKc_MAPKAPK3 |
| cd07873 | 123-368 | STKc_PCTAIRE1 |
| cd05111 | 119-343 | PTK_HER3 |
| cd14025 | 126-371 | STKc_RIP4_like |
| cd14102 | 238-380 | STKc_PIM3 |
| cd14190 | 126-380 | STKc_MLCK2 |
| cd13982 | 161-379 | STKc_IRE1 |
| cd05040 | 125-376 | PTKc_Ack_like |
| cd14097 | 126-380 | STKc_STK33 |
| cd14049 | 112-337 | STKc_EIF2AK1_HRI |
| cd05038 | 120-343 | PTKc_Jak_rpt2 |
| cd07864 | 117-317 | STKc_CDK12 |
| cd05069 | 125-385 | PTKc_Yes |
| cd14134 | 123-319 | PKc_CLK |
| cd07879 | 123-337 | STKc_p38delta |
| cd13995 | 179-377 | STKc_MAP3K8 |
| cd05588 | 126-387 | STKc_aPKC |
| cd05148 | 125-322 | PTKc_Srm_Brk |
| cd07858 | 126-336 | STKc_TEY_MAPK |
| cd14038 | 126-322 | STKc_IKK_beta |
| cd05589 | 126-322 | STKc_PKN |
| cd14226 | 112-347 | PKc_DYRK1 |
| cd05088 | 118-375 | PTKc_Tie2 |
| cd14055 | 127-290 | STKc_TGFbR2_like |
| cd14041 | 172-374 | STKc_TLK2 |
| cd14184 | 126-359 | STKc_DCKL2 |
| cd14170 | 126-322 | STKc_MAPKAPK2 |
| cd05629 | 118-265 | STKc_NDR_like_fungal |
| cd14039 | 126-340 | STKc_IKK_alpha |
| cd14026 | 119-343 | STKc_RIP2 |
| cd14016 | 127-275 | STKc_CK1 |
| cd14135 | 123-324 | STKc_PRP4 |
| cd07842 | 121-412 | STKc_CDK8_like |
| cd14036 | 141-324 | STKc_GAK |
| cd14076 | 126-380 | STKc_Kin4 |
| cd14160 | 126-319 | PK_IRAK3 |
| cd05070 | 125-385 | PTKc_Fyn |
| cd13998 | 127-412 | STKc_TGFbR-like |
| cd14155 | 126-360 | PKc_TESK |
| cd05089 | 126-341 | PTKc_Tie1 |
| cd05082 | 119-377 | PTKc_Csk |
| cd07844 | 121-332 | STKc_PCTAIRE_like |
| cd07872 | 123-336 | STKc_PCTAIRE2 |
| cd14108 | 125-377 | STKc_SPEG_rpt1 |
| cd14030 | 125-381 | STKc_WNK1 |
| cd14192 | 126-380 | STKc_MLCK3 |
| cd07850 | 112-321 | STKc_JNK |
| cd07849 | 180-323 | STKc_ERK1_2_like |
| cd14212 | 126-318 | PKc_YAK1 |
| cd05054 | 240-377 | PTKc_VEGFR |
| cd14222 | 126-374 | STKc_LIMK2 |
| cd14113 | 123-369 | STKc_Trio_C |
| cd05075 | 126-374 | PTKc_Axl |
| cd07855 | 126-383 | STKc_ERK5 |
| cd05576 | 141-319 | STKc_RPK118_like |
| cd14018 | 206-372 | STKc_PINK1 |
| cd07865 | 116-317 | STKc_CDK9 |
| cd05063 | 126-371 | PTKc_EphR_A2 |
| cd14112 | 216-380 | STKc_Unc-89_rpt2 |
| cd14087 | 126-380 | STKc_PSKH1 |
| cd14136 | 190-320 | STKc_SRPK |
| cd14183 | 115-380 | STKc_DCKL1 |
| cd05043 | 222-322 | PTK_Ryk |
| cd05055 | 126-374 | PTKc_PDGFR |
| cd07878 | 111-321 | STKc_p38beta |
| cd14086 | 226-392 | STKc_CaMKII |
| cd14109 | 224-380 | PK_Unc-89_rpt1 |
| cd07853 | 126-315 | STKc_NLK |
| cd05053 | 112-376 | PTKc_FGFR |
| cd07857 | 123-337 | STKc_MPK1 |
| cd14193 | 126-336 | STKc_MLCK4 |
| cd05097 | 145-380 | PTKc_DDR_like |
| cd07854 | 192-319 | STKc_MAPK4_6 |
| cd13975 | 214-369 | PKc_Dusty |
| cd14153 | 226-376 | PK_KSR2 |
| cd05061 | 123-397 | PTKc_InsR |
| cd14063 | 226-375 | PK_KSR |
| cd14229 | 121-345 | STKc_HIPK3 |
| cd14011 | 226-379 | PK_SCY1_like |
| cd05045 | 126-382 | PTKc_RET |
| cd14015 | 193-374 | STKc_VRK |
| cd14159 | 126-339 | STKc_IRAK1 |
| cd05102 | 240-376 | PTKc_VEGFR3 |
| cd07876 | 110-323 | STKc_JNK2 |
| cd07874 | 111-315 | STKc_JNK3 |
| cd05074 | 214-322 | PTKc_Tyro3 |
| cd14111 | 224-322 | STKc_SPEG_rpt2 |
| cd14224 | 121-318 | PKc_DYRK2_3 |
| cd05035 | 214-376 | PTKc_TAM |
| cd07875 | 121-321 | STKc_JNK1 |
| cd05625 | 126-342 | STKc_LATS1 |
| cd05104 | 226-376 | PTKc_Kit |
| cd14067 | 123-321 | STKc_LRRK1 |
| cd14206 | 123-339 | PTKc_Aatyk3 |
| cd05081 | 120-332 | PTKc_Jak3_rpt2 |
| cd05079 | 120-386 | PTKc_Jak1_rpt2 |
| cd05080 | 120-376 | PTKc_Tyk2_rpt2 |
| cd07859 | 126-341 | STKc_TDY_MAPK |
| cd14132 | 226-379 | STKc_CK2_alpha |
| cd05105 | 223-376 | PTKc_PDGFR_alpha |
| cd05064 | 124-382 | PTKc_EphR_A10 |
| cd05098 | 226-376 | PTKc_FGFR1 |
| cd05107 | 226-375 | PTKc_PDGFR_beta |
| cd14227 | 118-318 | STKc_HIPK2 |
| cd07869 | 121-321 | STKc_PFTAIRE1 |
| cd14042 | 138-344 | PK_GC-A_B |
| cd13974 | 223-378 | STKc_SHIK |
| cd14228 | 118-318 | STKc_HIPK1 |
| cd14138 | 112-378 | PTKc_Wee1a |
| cd07866 | 117-379 | STKc_BUR1 |
| cd14144 | 126-325 | STKc_BMPR1 |
| cd07867 | 125-374 | STKc_CDC2L6 |
| cd14068 | 126-369 | STKc_LRRK2 |
| cd14211 | 121-318 | STKc_HIPK |
| cd05042 | 123-344 | PTKc_Aatyk |
| cd05101 | 223-376 | PTKc_FGFR2 |
| cd05090 | 222-374 | PTKc_Ror1 |
| cd05086 | 125-344 | PTKc_Aatyk2 |
| cd05062 | 125-337 | PTKc_IGF-1R |
| cd05050 | 118-322 | PTKc_Musk |
| cd14204 | 119-377 | PTKc_Mer |
| cd05099 | 146-376 | PTKc_FGFR4 |
| cd05106 | 240-374 | PTKc_CSF-1R |
| cd14054 | 127-317 | STKc_BMPR2_AMHR2 |
| cd14152 | 226-324 | STKc_KSR1 |
| cd14214 | 121-347 | PKc_CLK3 |
| cd14053 | 226-317 | STKc_ACVR2 |
| cd14088 | 133-322 | STKc_CaMK_like |
| cd05049 | 124-322 | PTKc_Trk |
| cd14124 | 172-374 | PK_VRK3 |
| smart00220 | 121-380 | S_TKc |
| pfam00069 | 120-380 | Pkinase |
| COG0515 | 121-389 | SPS1 |
| PLN00034 | 24-382 | PLN00034 |
| pfam07714 | 120-377 | Pkinase_Tyr |
| smart00219 | 120-376 | TyrKc |
| smart00221 | 120-376 | STYKc |
| PTZ00263 | 116-368 | PTZ00263 |
| PTZ00283 | 126-383 | PTZ00283 |
| PTZ00267 | 179-403 | PTZ00267 |
| PHA03390 | 209-381 | pk1 |
| PTZ00266 | 114-381 | PTZ00266 |
| PHA03212 | 141-319 | PHA03212 |
| PTZ00036 | 114-337 | PTZ00036 |
| TIGR03903 | 142-368 | TOMM_kin_cyc |
| PHA03209 | 206-345 | PHA03209 |
| PHA03207 | 212-316 | PHA03207 |
| PTZ00426 | 119-397 | PTZ00426 |
| PLN00009 | 121-321 | PLN00009 |
| PTZ00024 | 126-324 | PTZ00024 |
| PRK13184 | 111-326 | pknD |
| COG0661 | 237-268 | AarF |
| TIGR01982 | 236-268 | UbiB |
Ontology Information
| HPRD ID | 5482 |
|---|---|
| Molecular Class | Dual specificity kinase |
| Molecular Function | Protein serine/threonine phosphatase activity (GO:0004722) |
| Biological Process | Cell communication (GO:0007154); Signal transduction (GO:0007165) |
Drug Information
No matching records could be found.