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General Information



Gene_Symbol Gene_ID Gene_Name Chromosome Alias
EIF5A2 56648 eukaryotic translation initiation factor 5A2  3- 







  • Evidence
  • Gene
  • mRNA
  • CDS
  • Protein
  • PTM
  • Enzyme
  • PPi
  • Pathway
  • Structural
  • Domain
  • Ontology
  • SNP
  • Drug
  • External Links



Evidence Information


Pubmed ID Year Sample Information Techniques Mechanism Fold Change Remark
21813470   2012Cell line : -

Source : -

Sample Type : CRC tumor and normal tissue

No. of Sample : -

Stage : -

ImmunohistochemistryUp-regulation- EIF5A2 plays an important oncogenic role in CRC aggressiveness by the upregulation of MTA1 to induce EMT, and EIF5A2 could be employed as a novel prognostic marker and/or effective therapeutic target for CRC.


Gene Details



NC_000003.11 (170606204..170626426, complement)

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Gene Type protein coding
Gene Family -
Description -  
Chromosome 3
Location 3q26.2
Start 170606204  
End 170626426  
Strand -  
Gene Sequence

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Length 20223  
OMIM ID 605782   
HGNC ID HGNC:3301   
Unigene ID Hs.164144   
Ensembl ID ENSG00000163577   
PharmGKB ID PA27727   

mRNA Information


mRNA ID ?NM_020390.5
Exon  
mRNA Sequence

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Length  



CDS Information


   
Location
CDS Sequence

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CCDS ID CCDS3214.1



Protein Information


      
Protein IDNP_065123.1
Protein Nameeukaryotic translation initiation factor 5A2
Molecular Wt. (Da)0
Protein Sequence

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Length 153  
Uniprot IDQ86V24
Ensembl Protein ID ENSP00000349616  



Post-translational Modification Information (Source : HPRD)


Residue Type site
CS-Nitrosylation73

Enzyme Information


No matching records could be found.

PPi Information


(Click to view network : Source STRING)      View   

No matching records from HPRD source could be found.

Pathway Information


No matching records could be found.

Structure Information


No matching records could be found.

Domain Information




ID Location Description
cd0446884-152  S1_eIF5A
cl0992784-152  S1_like superfamily
pfam0128783-150  eIF-5a
cd0446989-150  S1_Hex1
PLN031071-150  PLN03107
TIGR0003714-150  eIF_5A
PTZ003283-150  PTZ00328
COG023117-151  Efp
PRK0399916-135  PRK03999
TIGR0003825-90  efp


Ontology Information


   
HPRD ID13561
Molecular ClassTranslation regulatory protein
Molecular FunctionGalactosyltransferase activity (GO:0008378)
Biological ProcessMetabolism (GO:0008152); Energy pathways (GO:0006091)  



SNP Information


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Drug Information


No matching records could be found.

External Links


                                 
ArrayExpressGO
ICGCGO
Cancer3DGO
COSMICGO
NCGGO
TSGeneGO
Tumor Gene Family of DatabasesGO
CCDBGO
G2SBCGO
Osteosarcoma DatabaseGO
RCDBGO