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General Information
- Evidence
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Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 22914648 | 2012 | Cell line : LoVo, HT 29, T 84, SW620, SW480, SW48 Source : - Sample Type : CRC tumor tissue array No. of Sample : Tissue microarrays (TMAs) containing colon cancer tissues of various grades and adjacent normal tissues from eight patients Stage : TNM Stage I-IV | Immunohistochemistry,tissue microarrays,RT-PCR | Up-regulation | - | Significant increase in MUC13 expression in metastatic colon cancer and suggest a correlation between aberrant MUC13 localization (cytoplasmic and nuclear expression) and metastatic colon cancer. |
| 24097071 | 2014 | Cell line : SW48,SW480,SW620,T84, HT 29 Source : ATCC Sample Type : - No. of Sample : - Stage : - | Cell growth, colony formation, cell migration, and cell invasion assays,chromatin immunoprecipitation ,immunohistochemistry . | Up-regulation | - | Overexpression of MUC13 increased cell growth, colony formation, cell migration, and invasion. |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | Mucins |
| Description | Epithelial mucins, such as MUC13, are a family of secreted and cell surface glycoproteins expressed by ductal and glandular epithelial tissues (Williams et al., 2001 [PubMed 11278439]).[supplied by OMIM, Jul 2008] |
| Chromosome | 3 |
| Location | 3q21.2 |
| Start | 124624289 |
| End | 124653595 |
| Strand | - |
| Gene Sequence | Download Select all |
| Length | 29307 |
| OMIM ID | 612181 |
| HGNC ID | HGNC:7511 |
| Unigene ID | Hs.5940 |
| Ensembl ID | ENSG00000173702 |
| PharmGKB ID | PA31312 |
Protein Information
| Protein ID | NP_149038.3 |
|---|---|
| Protein Name | mucin 13, cell surface associated |
| Molecular Wt. (Da) | 0 |
| Protein Sequence | Download Select all |
| Length | 512 |
| Uniprot ID | Q6V0I7 |
| Ensembl Protein ID | ENSP00000335169 |
Post-translational Modification Information (Source : HPRD)
No matching records could be found.
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
No matching records from HPRD source could be found.
Pathway Information
No matching records could be found.
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| pfam01390 | 211-315 | SEA |
| cl02507 | 211-315 | SEA superfamily |
| TIGR04561 | 419-468 | membra_charge |
| cl22843 | 419-468 | membra_charge superfamily |
| PRK11907 | 2-122 | PRK11907 |
| pfam05109 | 15-175 | Herpes_BLLF1 |
| PRK10856 | 16-110 | PRK10856 |
| COG3889 | 29-121 | COG3889 |
| pfam05109 | 15-176 | Herpes_BLLF1 |
| COG3889 | 40-126 | COG3889 |
| PHA03247 | 23-176 | PHA03247 |
| pfam03154 | 35-176 | Atrophin-1 |
| PRK12799 | 16-152 | motB |
| PRK13335 | 10-153 | PRK13335 |
| pfam03154 | 21-174 | Atrophin-1 |
| pfam05109 | 12-173 | Herpes_BLLF1 |
| PLN02217 | 9-117 | PLN02217 |
| PRK14950 | 25-107 | PRK14950 |
| PHA03307 | 18-175 | PHA03307 |
| pfam05109 | 24-176 | Herpes_BLLF1 |
| PRK10118 | 3-104 | PRK10118 |
| PHA03255 | 24-151 | PHA03255 |
| PRK10856 | 52-128 | PRK10856 |
| PHA03255 | 1-162 | PHA03255 |
| PRK11907 | 24-140 | PRK11907 |
| pfam09786 | 64-162 | CytochromB561_N |
| PRK14971 | 30-158 | PRK14971 |
Ontology Information
| HPRD ID | 7022 |
|---|---|
| Molecular Class | Integral membrane protein |
| Molecular Function | Transporter activity (GO:0005215) |
| Biological Process | Cell communication (GO:0007154); Signal transduction (GO:0007165) |
Drug Information
No matching records could be found.