Search results:
General Information
| Gene_Symbol | Gene_ID | Gene_Name | Chromosome | Alias |
|---|---|---|---|---|
| DUSP22 | 56940 | dual specificity phosphatase 22 | 6 | MKPX, JSP1, JKAP, VHX |
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 26032091 | 2015 | Cell line : - Source : - Sample Type : CRC tumor and normal tissue No. of Sample : 92 Stage : - | QuantiGenePlex assay,Mann-Whitney test and Kruskal-Wallis test | Down-regulation | - | Low expression level of DUSP22 in stage IV patients had a poor survival outcome. |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | Protein tyrosine phosphatases / Class I Cys-based PTPs : Atypical dual specificity phosphatases |
| Description | - |
| Chromosome | 6 |
| Location | 6p25.3 |
| Start | 292101 |
| End | 351355 |
| Strand | + |
| Gene Sequence | Download Select all |
| Length | 59255 |
| OMIM ID | - |
| HGNC ID | HGNC:16077 |
| Unigene ID | Hs.29106 |
| Ensembl ID | ENSG00000112679 |
| PharmGKB ID | PA134991025 |
Protein Information
| Protein ID | NP_001273484.1 |
|---|---|
| Protein Name | dual specificity phosphatase 22 |
| Molecular Wt. (Da) | 0 |
| Protein Sequence | Download Select all |
| Length | 184 |
| Uniprot ID | Q9H9S0 |
| Ensembl Protein ID | ENSP00000229307 |
Post-translational Modification Information (Source : HPRD)
| Residue | Type | site |
|---|---|---|
| G | Myristoylation | 2 |
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
| Interactant Gene ID (Source: HPRD) | Gene Symbol | HPRD ID | Ref Seq ID | Technique | References |
|---|---|---|---|---|---|
| 1432 | MAPK14 | 2619 | NP_001306.1 | in vitro;in vivo | 11346645 |
| 5599 | MAPK8 | 3100 | NP_620637.1 | in vivo | 12138158 |
| 5609 | MAP2K7 | 4309 | AAC16273.1 | in vitro;in vivo | 12138158 |
| 6416 | MAP2K4 | 3213 | NP_003001.1 | in vitro;in vivo | 11346645 |
Pathway Information
No matching records could be found.
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| cd00127 | 4-139 | DSPc |
| cl21483 | 4-139 | PTPc superfamily |
| smart00195 | 5-140 | DSPc |
| pfam00782 | 12-140 | DSPc |
| smart00404 | 51-104 | PTPc_motif |
| smart00012 | 51-104 | PTPc_DSPc |
| COG5350 | 20-128 | COG5350 |
| cd00047 | 59-104 | PTPc |
| COG2453 | 41-158 | CDC14 |
| PRK12361 | 5-140 | PRK12361 |
| pfam00102 | 71-124 | Y_phosphatase |
| smart00194 | 71-124 | PTPc |
Ontology Information
| HPRD ID | 7855 |
|---|---|
| Molecular Class | Dual specificity phosphatase |
| Molecular Function | Molecular function unknown (GO:0005554) |
| Biological Process | Biological_process unknown (GO:0000004) |
Drug Information
No matching records could be found.