Search results:
General Information
| Gene_Symbol | Gene_ID | Gene_Name | Chromosome | Alias |
|---|---|---|---|---|
| GOPC | 57120 | Golgi associated PDZ and coiled-coil motif containing | 6 | CAL; FIG; PIST; GOPC1; dJ94G16.2 |
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 20089989 | 2010 | Cell line : - Source : VU University Medical Center, Amsterdam, The Netherlands. Sample Type : CRC tumor and normal tissue No. of Sample : - Stage : TNM Stage II | Biochemical isolation to nano-LC-MS/MS analysis | Down-regulation | - | - |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | - |
| Description | This gene encodes a Golgi protein with a PDZ domain. The PDZ domain is globular and proteins which contain them bind other proteins through short motifs near the C-termini. Mice which are deficient in the orthologous protein have globozoospermia and are infertile. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011] |
| Chromosome | 6 |
| Location | 6q21 |
| Start | 117560269 |
| End | 117602542 |
| Strand | + |
| Gene Sequence | Download Select all |
| Length | 42274 |
| OMIM ID | 606845 |
| HGNC ID | HGNC:17643 |
| Unigene ID | Hs.191539 |
| Ensembl ID | ENSG00000047932 |
| PharmGKB ID | - |
mRNA Information
| mRNA ID | NM_173674.1 |
|---|---|
| Exon | complement(<32685..32923) | mRNA Sequence | Download Select all |
| Length | 4616 |
CDS Information
| Location | complement(<32919..32923) |
|---|---|
| CDS Sequence | Download Select all |
| CCDS ID | CCDS34522.1 |
Protein Information
| Protein ID | NP_001017408.1 |
|---|---|
| Protein Name | Golgi associated PDZ and coiled-coil motif containing |
| Molecular Wt. (Da) | 49590 |
| Protein Sequence | Download Select all |
| Length | 454 |
| Uniprot ID | P49789 |
| Ensembl Protein ID | ENSP00000417480 |
Post-translational Modification Information (Source : HPRD)
| Residue | Type | site |
|---|---|---|
| Y | Phosphorylation | 457 |
| Y | Phosphorylation | 462 |
| Y | Phosphorylation | 449 |
| Y | Phosphorylation | 454 |
| S | Acetylation | 2 |
| S | Acetylation | 2 |
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
| Interactant Gene ID (Source: HPRD) | Gene Symbol | HPRD ID | Ref Seq ID | Technique | References |
|---|---|---|---|---|---|
| 1080 | CFTR | 3883 | NP_000483.3 | in vivo;yeast 2-hybrid | 1 170 746 312 471 020 |
| 1182 | CLCN3 | 2785 | NP_776297.2 | in vitro;in vivo | 124 710 249 843 494 |
| 7855 | FZD5 | 3427 | NP_003459.2 | in vitro;in vivo;yeast 2-hybrid | 11520064 |
| 8325 | FZD8 | 5852 | NP_114072.1 | in vitro;in vivo;yeast 2-hybrid | 11520064 |
| 8678 | BECN1 | 5087 | NP_003757.1 | in vitro;in vivo;yeast 2-hybrid | 12372286 |
| 23433 | RHOQ | 5791 | NP_036381.2 | in vitro;in vivo;yeast 2-hybrid | 11162552 |
Pathway Information
No matching records could be found.
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| cd00992 | 286-368 | PDZ_signaling |
| cl00117 | 286-368 | PDZ superfamily |
| cd14686 | 166-200 | bZIP |
| cl21462 | 166-200 | bZIP superfamily |
| smart00228 | 286-369 | PDZ |
| pfam00595 | 288-367 | PDZ |
| cd00136 | 298-368 | PDZ |
| cd00988 | 297-361 | PDZ_CTP_protease |
| cd00989 | 299-367 | PDZ_metalloprotease |
| pfam07716 | 166-199 | bZIP_2 |
| cd00987 | 299-346 | PDZ_serine_protease |
| pfam13180 | 298-349 | PDZ_2 |
| cd14693 | 159-200 | bZIP_CEBP |
| TIGR02169 | 34-249 | SMC_prok_A |
| COG0793 | 297-353 | CtpA |
| TIGR02168 | 34-214 | SMC_prok_B |
| pfam05557 | 86-215 | MAD |
| PRK09039 | 45-222 | PRK09039 |
| COG3975 | 288-372 | COG3975 |
| TIGR02037 | 297-346 | degP_htrA_DO |
| COG1196 | 34-246 | Smc |
| TIGR02168 | 92-224 | SMC_prok_B |
| TIGR02169 | 83-223 | SMC_prok_A |
| TIGR04211 | 97-200 | SH3_and_anchor |
| TIGR02169 | 34-226 | SMC_prok_A |
| COG1196 | 93-229 | Smc |
| TIGR04211 | 83-193 | SH3_and_anchor |
| TIGR02169 | 54-214 | SMC_prok_A |
| PRK02224 | 94-215 | PRK02224 |
Ontology Information
| HPRD ID | 3053 |
|---|---|
| Molecular Class | Unclassified |
| Molecular Function | Transcription factor activity (GO:0003700) |
| Biological Process | Regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism (GO:0019219) |
Drug Information
No matching records could be found.