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General Information



Gene_Symbol Gene_ID Gene_Name Chromosome Alias
SALL4 57167 spalt-like transcription factor 4  20dJ1112F19.1, ZNF797 







  • Evidence
  • Gene
  • mRNA
  • CDS
  • Protein
  • PTM
  • Enzyme
  • PPi
  • Pathway
  • Structural
  • Domain
  • Ontology
  • SNP
  • Drug
  • External Links



Evidence Information


Pubmed ID Year Sample Information Techniques Mechanism Fold Change Remark
25156818   2014Cell line : -

Source : -

Sample Type : CRC tumor and normal tissue

No. of Sample : 111

Stage : -

real time RT-PCRUp-regulation-SALL4 as a critical biomarker for efficient screening of patients to detect early stages of CRC.

The blood copy number of SALL4 in recruited CRC patients was significantly higher than healthy controls


Gene Details



Chromosome 20 - NC_000020.11 (51784009..51913245, complement)

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Gene Type protein coding
Gene Family Zinc fingers, C2H2-type
Description The protein encoded by this gene may be a zinc finger transcription factor. Defects in this gene are a cause of Duane-radial ray syndrome (DRRS).  
Chromosome 20
Location 20q13.2
Start 51784009  
End 51913245  
Strand -  
Gene Sequence

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Length 129237  
OMIM ID 607343   
HGNC ID HGNC:15924   
Unigene ID Hs.517113   
Ensembl ID ENSG00000101115   
PharmGKB ID -   

mRNA Information


mRNA ID XM_011528919.1
Exon join(1..24,13009..13124,120894..123224,124105..124385, 128562..129237)  
mRNA Sequence

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Length 3487  



CDS Information


   
Location join(13121..13124,120894..123224,124105..124385, 128562..128981)
CDS Sequence

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CCDS ID -



Protein Information


      
Protein IDNP_065169.1
Protein Namespalt-like transcription factor 4
Molecular Wt. (Da)112101
Protein Sequence

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Length 1053  
Uniprot IDP01130
Ensembl Protein ID ENSP00000397829  



Post-translational Modification Information (Source : HPRD)


Residue Type site
SPhosphorylation116
SPhosphorylation121
SPhosphorylation530
TPhosphorylation541

Enzyme Information


No matching records could be found.

PPi Information


(Click to view network : Source STRING)      View   

No matching records from HPRD source could be found.

Pathway Information


No matching records could be found.

Structure Information


No matching records could be found.

Domain Information




ID Location Description
pfam13465580-605  zf-H2C2_2
cl22375580-605  zf-H2C2_2 superfamily
pfam13465884-909  zf-H2C2_2
cl22375884-909  zf-H2C2_2 superfamily
pfam13465396-421  zf-H2C2_2
cl22375396-421  zf-H2C2_2 superfamily
pfam00096898-920  zf-C2H2
cl23491898-920  zf-C2H2 superfamily
pfam00096594-616  zf-C2H2
cl23491594-616  zf-C2H2 superfamily
pfam00096626-648  zf-C2H2
cl23491626-648  zf-C2H2 superfamily
smart00355626-648  ZnF_C2H2
cl18194626-648  ZnF_C2H2 superfamily
smart00355382-404  ZnF_C2H2
cl18194382-404  ZnF_C2H2 superfamily
smart00355898-920  ZnF_C2H2
cl18194898-920  ZnF_C2H2 superfamily
cd11674791-891  lambda-1
cl17035791-891  lambda-1 superfamily
pfam00096382-404  zf-C2H2
cl23491382-404  zf-C2H2 superfamily
pfam00096872-892  zf-C2H2
cl23491872-892  zf-C2H2 superfamily
pfam13894382-404  zf-C2H2_4
cl20498382-404  zf-C2H2_4 superfamily
pfam13894626-648  zf-C2H2_4
cl20498626-648  zf-C2H2_4 superfamily
PHA00733593-645  PHA00733
COG5048562-920  COG5048


Ontology Information


   
HPRD ID1249
Molecular ClassTranscription factor
Molecular FunctionCytokine activity (GO:0005125)
Biological ProcessCell communication (GO:0007154); Signal transduction (GO:0007165)  



SNP Information


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Drug Information


No matching records could be found.

External Links


                                 
ArrayExpressGO
ICGCGO
Cancer3DGO
COSMICGO
NCGGO
TSGeneGO
Tumor Gene Family of DatabasesGO
CCDBGO
G2SBCGO
Osteosarcoma DatabaseGO
RCDBGO