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General Information



Gene_Symbol Gene_ID Gene_Name Chromosome Alias
ADAMTSL3 57188 ADAMTS-like 3  15KIAA1233, punctin-2 







  • Evidence
  • Gene
  • mRNA
  • CDS
  • Protein
  • PTM
  • Enzyme
  • PPi
  • Pathway
  • Structural
  • Domain
  • Ontology
  • SNP
  • Drug
  • External Links



Evidence Information


Pubmed ID Year Sample Information Techniques Mechanism Fold Change Remark
17597111   2007Cell line : -

Source : -

Sample Type : CRC tumor and normal tissues

No. of Sample : 10

Stage : -

real time RT- PCR Down-regulation/Mutation-ADAMTSL3 is expressed in numerous tissues, suggesting a broader regulatory role than in colorectal epithelium alone, and that colorectal cancer has both structural mutations as well as decreased expression of ADAMTSL3.


Gene Details



NC_000015.9 (84322838..84708594)

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Gene Type protein coding
Gene Family Immunoglobulin superfamily / I-set domain containing, "Immunoglobulin superfamily / Immunoglobulin-like domain containing"
Description -  
Chromosome 15
Location 15q25.2
Start 84322838  
End 84708594  
Strand +  
Gene Sequence

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Length 385757  
OMIM ID 609199   
HGNC ID HGNC:14633   
Unigene ID Hs.459162   
Ensembl ID ENSG00000156218   
PharmGKB ID PA134934525   

mRNA Information


mRNA ID ?NM_001301110.1
Exon  
mRNA Sequence

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Length  



CDS Information


   
Location
CDS Sequence

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CCDS ID CCDS10326.1



Protein Information


      
Protein IDNP_001288039.1
Protein NameADAMTS-like 3
Molecular Wt. (Da)0
Protein Sequence

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Length 1691  
Uniprot IDQ96SN7
Ensembl Protein ID ENSP00000348752  



Post-translational Modification Information (Source : HPRD)


No matching records could be found.

Enzyme Information


No matching records could be found.

PPi Information


(Click to view network : Source STRING)      View   

No matching records from HPRD source could be found.

Pathway Information


No matching records could be found.

Structure Information


No matching records could be found.

Domain Information




ID Location Description
cd000961211-1275  Ig
cl119601211-1275  Ig superfamily
cd049691314-1382  Ig5_Contactin_like
cl119601314-1382  Ig superfamily
cd000961317-1379  Ig
cd057251317-1382  Ig3_Robo
cd057241309-1374  Ig2_Robo
cd057311317-1376  Ig3_L1-CAM_like
cd049681309-1375  Ig3_Contactin_like
cd057361318-1374  Ig2_Follistatin_like
cd057301311-1384  Ig3_NCAM-1_like
cd049781314-1385  Ig4_L1-NrCAM_like
cd04969929-993  Ig5_Contactin_like
cl11960929-993  Ig superfamily
cd057641314-1384  Ig_2
cd057541309-1383  Ig3_Perlecan_like
smart0020978-124  TSP1
cl1527878-124  TSP_1 superfamily
cd058511309-1375  Ig3_Contactin-1
cd058521314-1382  Ig5_Contactin-1
pfam086861659-1690  PLAC
cl073441659-1690  PLAC superfamily
cd057461317-1382  Ig4_Peroxidasin
cd049741314-1385  Ig3_FGFR
cd057281310-1382  Ig4_Contactin-2-like
cd057291313-1379  Ig2_FGFR_like
pfam000471314-1369  ig
cd057381318-1374  Ig2_RPTP_IIa_LAR_like
cd057221314-1371  Ig1_Neogenin
pfam138951314-1371  Ig_2
pfam139271314-1371  Ig_3
cd057341317-1380  Ig7_DSCAM
cd058761317-1376  Ig3_L1-CAM
cd057451314-1374  Ig3_Peroxidasin
cd058571314-1374  Ig2_FGFR
cd058561308-1379  Ig2_FGFRL1-like
cd076931314-1377  Ig1_Robo
cd057261314-1384  Ig4_Robo
cd058581314-1385  Ig3_FGFR-2
cd057651314-1374  Ig_3
cd049721313-1379  Ig_TrkABC_d4
smart00209707-760  TSP1
cl15278707-760  TSP_1 superfamily
cd05852930-995  Ig5_Contactin-1
cd049691223-1279  Ig5_Contactin_like
cd058671314-1385  Ig4_L1-CAM_like
cd058691313-1375  Ig5_NCAM-1
cd058481317-1374  Ig1_Contactin-5
cd057331317-1377  Ig6_L1-CAM_like
cd057321317-1374  Ig5_NCAM-1_like
cd057471314-1378  Ig5_Titin_like
smart00209486-515  TSP1
cl15278486-515  TSP_1 superfamily
cd05746930-993  Ig4_Peroxidasin
pfam00090710-759  TSP_1
cd057231316-1382  Ig4_Neogenin
cd049671317-1379  Ig1_Contactin
cd049711323-1385  Ig_TrKABC_d5
smart00209826-881  TSP1
cl15278826-881  TSP_1 superfamily
cd057741329-1365  Ig_CEACAM_D1
cd057331211-1279  Ig6_L1-CAM_like
pfam0009081-123  TSP_1
cd05729927-984  Ig2_FGFR_like
pfam076861309-1371  V-set
cd05723930-993  Ig4_Neogenin
smart00209426-446  TSP1
cl15278426-446  TSP_1 superfamily
cd057481316-1379  Ig_Titin_like
cd057461211-1271  Ig4_Peroxidasin
cd057441317-1382  Ig_Myotilin_C_like
cd00096930-984  Ig
cd057601317-1376  Ig2_PTK7
smart00209763-820  TSP1
cl15278763-820  TSP_1 superfamily
cd057411314-1365  Ig_CEACAM_D1_like
cd057391314-1382  Ig3_RPTP_IIa_LAR_like
smart00209571-591  TSP1
cl15278571-591  TSP_1 superfamily
cd049791309-1386  Ig_Semaphorin_C
cd05724929-984  Ig2_Robo
cd057431314-1379  Ig_Perlecan_D2_like
smart004081314-1374  IGc2
smart004081211-1270  IGc2
smart00408926-987  IGc2
smart004101309-1383  IG_like
smart004091309-1383  IG
pfam076791309-1383  I-set
pfam07679929-994  I-set
pfam076791226-1278  I-set
smart00410929-994  IG_like
smart00409929-994  IG
smart004101209-1278  IG_like
smart004091209-1278  IG


Ontology Information


   
HPRD ID9694
Molecular ClassMetallo protease
Molecular FunctionDNA binding (GO:0003677)
Biological ProcessRegulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism (GO:0019219)  



SNP Information


View SNP Geneview Report   

Drug Information


No matching records could be found.

External Links


                                 
ArrayExpressGO
ICGCGO
Cancer3DGO
COSMICGO
NCGGO
TSGeneGO
Tumor Gene Family of DatabasesGO
CCDBGO
G2SBCGO
Osteosarcoma DatabaseGO
RCDBGO