Search results:
General Information
| Gene_Symbol | Gene_ID | Gene_Name | Chromosome | Alias |
|---|---|---|---|---|
| S100A14 | 57402 | S100 calcium binding protein A14 | 1 | S100A15, BCMP84 |
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 19956863 | 2010 | Cell line : - Source : - Sample Type : Formalin-fixed and paraffin-embedded tumors tissue No. of Sample : 115 Stage : - | Immunohistochemistry,tissue microarrays,RT-PCR | Down-regulation | - | S100A14 low-expression and S100A4 high-expression was correlated with high CRC metastatic potential (P<0.001). |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | S100 calcium binding proteins |
| Description | This gene encodes a member of the S100 protein family which contains an EF-hand motif and binds calcium. The gene is located in a cluster of S100 genes on chromosome 1. Levels of the encoded protein have been found to be lower in cancerous tissue and associated with metastasis suggesting a tumor suppressor function (PMID: 19956863, 19351828). [provided by RefSeq, Dec 2011] |
| Chromosome | 1 |
| Location | 1q21.1 |
| Start | 153586731 |
| End | 153588808 |
| Strand | - |
| Gene Sequence | Download Select all |
| Length | 2078 |
| OMIM ID | 607986 |
| HGNC ID | HGNC:18901 |
| Unigene ID | Hs.288998 |
| Ensembl ID | ENSG00000189334 |
| PharmGKB ID | PA134905502 |
Protein Information
| Protein ID | NP_065723.1 |
|---|---|
| Protein Name | S100 calcium binding protein A14 |
| Molecular Wt. (Da) | 0 |
| Protein Sequence | Download Select all |
| Length | 104 |
| Uniprot ID | Q9BUP0 |
| Ensembl Protein ID | ENSP00000264059 |
Post-translational Modification Information (Source : HPRD)
No matching records could be found.
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
| Interactant Gene ID (Source: HPRD) | Gene Symbol | HPRD ID | Ref Seq ID | Technique | References |
|---|---|---|---|---|---|
| 140576 | S100A16 | 11529 | NP_525127.1 | yeast 2-hybrid | 16189514 |
Pathway Information
No matching records could be found.
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| cd05022 | 16-104 | S-100A13 |
| cl08302 | 16-104 | EFh superfamily |
| cd00213 | 16-98 | S-100 |
| cd05030 | 16-88 | calgranulins |
| pfam01023 | 19-59 | S_100 |
| cl19180 | 19-59 | S_100 superfamily |
| cd05031 | 16-88 | S-100A10_like |
| cd05027 | 16-84 | S-100B |
| cd05024 | 16-88 | S-100A10 |
| cd05025 | 16-88 | S-100A1 |
| cd05026 | 16-88 | S-100Z |
| cd05029 | 16-54 | S-100A6 |
Ontology Information
| HPRD ID | 11705 |
|---|---|
| Molecular Class | Calcium binding protein |
| Molecular Function | Transcription factor activity (GO:0003700) |
| Biological Process | Regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism (GO:0019219) |
Drug Information
No matching records could be found.