Search results:
General Information
| Gene_Symbol | Gene_ID | Gene_Name | Chromosome | Alias |
|---|---|---|---|---|
| WDR48 | 57599 | WD repeat domain 48 | 3 | KIAA1449, P80, SPG60 |
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 24145035 | 2013 | Cell line : HEK 293T, HeLa, HCT116 Source : - Sample Type : - No. of Sample : - Stage : - | Cell Transfections, Immunoprecipitation, and Immunoblotting,GST Pulldown Assays ,In Vivo Ubiquitination Assay,Apoptosis Assay,Cell Proliferation Assay | Down-regulation | - | WDR48 and USP12 as novel PHLPP1 regulators and potential suppressors of tumor cell survival. |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | WD repeat domain containing |
| Description | - |
| Chromosome | 3 |
| Location | 3p21.33 |
| Start | 39093477 |
| End | 39138155 |
| Strand | + |
| Gene Sequence | Download Select all |
| Length | 44679 |
| OMIM ID | 612167 |
| HGNC ID | HGNC:30914 |
| Unigene ID | Hs.109778 |
| Ensembl ID | ENSG00000114742 |
| PharmGKB ID | PA134956949 |
Protein Information
| Protein ID | NP_001290331.1 |
|---|---|
| Protein Name | WD repeat domain 48 |
| Molecular Wt. (Da) | 0 |
| Protein Sequence | Download Select all |
| Length | 677 |
| Uniprot ID | Q9H211 |
| Ensembl Protein ID | ENSP00000301019 |
Post-translational Modification Information (Source : HPRD)
| Residue | Type | site |
|---|---|---|
| K | Acetylation | 214 |
| K | Acetylation | 121 |
| K | Acetylation | 578 |
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
No matching records from HPRD source could be found.
Pathway Information
| Pathway Name | Pathway ID |
|---|---|
| Fanconi anemia pathway | hsa03460 |
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| cd00200 | 30-286 | WD40 |
| cl02567 | 30-286 | WD40 superfamily |
| pfam11816 | 366-677 | DUF3337 |
| cl13285 | 366-677 | DUF3337 superfamily |
| cd00200 | 31-238 | WD40 |
| cd00200 | 109-282 | WD40 |
| cd00200 | 206-295 | WD40 |
| pfam00400 | 202-238 | WD40 |
| pfam00400 | 68-103 | WD40 |
| smart00320 | 199-238 | WD40 |
| smart00320 | 68-103 | WD40 |
| pfam00400 | 107-145 | WD40 |
| smart00320 | 106-145 | WD40 |
| pfam00400 | 161-196 | WD40 |
| smart00320 | 162-196 | WD40 |
| smart00320 | 241-280 | WD40 |
| COG2319 | 29-328 | WD40 |
| COG2319 | 31-391 | WD40 |
| COG2319 | 14-245 | WD40 |
| COG2319 | 72-409 | WD40 |
| PLN00181 | 113-286 | PLN00181 |
| PTZ00421 | 44-202 | PTZ00421 |
| PLN00181 | 10-269 | PLN00181 |
| PTZ00421 | 41-151 | PTZ00421 |
| PTZ00421 | 134-306 | PTZ00421 |
Ontology Information
| HPRD ID | 5862 |
|---|---|
| Molecular Class | Unclassified |
| Molecular Function | Metallopeptidase activity (GO:0008237) |
| Biological Process | Protein metabolism (GO:0019538) |
Drug Information
No matching records could be found.