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General Information



Gene_Symbol Gene_ID Gene_Name Chromosome Alias
BAI2 576 brain-specific angiogenesis inhibitor 2  1- 







  • Evidence
  • Gene
  • mRNA
  • CDS
  • Protein
  • PTM
  • Enzyme
  • PPi
  • Pathway
  • Structural
  • Domain
  • Ontology
  • SNP
  • Drug
  • External Links



Evidence Information


Pubmed ID Year Sample Information Techniques Mechanism Fold Change Remark
19034969   2008Cell line : -

Source : Asan Medical Center (Seoul, Korea).

Sample Type : CRC tumor and normal tissues

No. of Sample : 84

Stage : AJCC Stage I-IV

cDNA microarray and data analysis,RT-PCR,Parametric analysis of gene set enrichmentUp-regulation--


Gene Details



NC_000001.10 (32192718..32230494, complement)

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Gene Type protein coding
Gene Family -, "GPCR / Class B : Orphans"
Description This gene encodes a a seven-span transmembrane protein that is thought to be a member of the secretin receptor family. The encoded protein is a brain-specific inhibitor of angiogenesis. The mature peptide may be further cleaved into additional products (PMID:20367554). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014]  
Chromosome 1
Location 1p35
Start 32192718  
End 32230494  
Strand -  
Gene Sequence

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Length 37777  
OMIM ID 602683   
HGNC ID HGNC:944   
Unigene ID Hs.524138   
Ensembl ID ENSG00000121753   
PharmGKB ID PA25248   

mRNA Information


mRNA ID NM_001294336.1
Exon join(1..180,6553..6682,6783..6863,7249..8065,19333..19416, 19707..19871,21062..21226,21847..22011,22097..22264, 22339..22440,22585..22691,23523..23717,23886..23954, 24030..24138,24429..24756,25127..25232,25434..25477, 25738..25864,26309..26412,26533..26635,27341..27491, 27674..27743,28171..28237,28399..28484,30921..31092, 31452..31547,31910..31949,32645..33264,35431..35466, 35787..35882,35983..36039,36459..36959)  
mRNA Sequence

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Length 5356  



CDS Information


   
Location371..5026
CDS Sequence

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CCDS ID CCDS72746.1



Protein Information


      
Protein IDNP_001281265.1
Protein Namebrain-specific angiogenesis inhibitor 2
Molecular Wt. (Da)165749
Protein Sequence

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Length 155  
Uniprot IDP08473
Ensembl Protein ID ENSP00000353679  



Post-translational Modification Information (Source : HPRD)


No matching records could be found.

Enzyme Information


No matching records could be found.

PPi Information


(Click to view network : Source STRING)      View   

               
Interactant Gene ID (Source: HPRD) Gene Symbol HPRD ID Ref Seq ID Technique References
84064HDHD213640NP_115500.1yeast 2-hybrid16169070   


Pathway Information


No matching records could be found.

Structure Information


No matching records could be found.

Domain Information




ID Location Description
pfam00002929-1198  7tm_2
cl21587929-1198  7tm_2 superfamily
pfam12003606-772  DUF3497
cl13441606-772  DUF3497 superfamily
smart00209367-417  TSP1
cl15278367-417  TSP_1 superfamily
smart00303870-923  GPS
cl02559870-923  GPS superfamily
pfam01825872-918  GPS
smart00209314-362  TSP1
cl15278314-362  TSP_1 superfamily
smart00209478-528  TSP1
cl15278478-528  TSP_1 superfamily
smart00209422-472  TSP1
cl15278422-472  TSP_1 superfamily
pfam00090314-356  TSP_1
pfam00090369-416  TSP_1
smart00008531-595  HormR
cl02422531-595  HRM superfamily
pfam00090424-471  TSP_1
pfam00090479-527  TSP_1
pfam02793531-590  HRM
PTZ00087314-355  PTZ00087
PTZ00441359-419  PTZ00441
PTZ00441425-472  PTZ00441
PTZ00441438-528  PTZ00441


Ontology Information


   
HPRD ID384
Molecular ClassIntegral membrane protein
Molecular FunctionMetallopeptidase activity (GO:0008237)
Biological ProcessProtein metabolism (GO:0019538)  



SNP Information


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Drug Information


No matching records could be found.

External Links


                                 
ArrayExpressGO
ICGCGO
Cancer3DGO
COSMICGO
NCGGO
TSGeneGO
Tumor Gene Family of DatabasesGO
CCDBGO
G2SBCGO
Osteosarcoma DatabaseGO
RCDBGO