Search results:
General Information
| Gene_Symbol | Gene_ID | Gene_Name | Chromosome | Alias |
|---|---|---|---|---|
| PTX3 | 5806 | Pentraxin-related gene, rapidly induced by IL-1 beta | 3 | TSG-14; TNFAIP5 |
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 22930170 | 2012 | Cell line : KM 12C, KM 12SM, HT 29 Source : ATCC Sample Type : - No. of Sample : - Stage : - | Microarray analysis,Real time RT-PCR and Flow cytometry | Up-regulation | - | Gene differentially expressed and analysed bye by Microarray. |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | - |
| Description | - |
| Chromosome | 3 |
| Location | 3q25 |
| Start | 157436791 |
| End | 157443628 |
| Strand | + |
| Gene Sequence | Download Select all |
| Length | 6838 |
| OMIM ID | 602492 |
| HGNC ID | HGNC:9692 |
| Unigene ID | Hs.591286 |
| Ensembl ID | ENSG00000163661 |
| PharmGKB ID | - |
mRNA Information
| mRNA ID | NM_002852.3 |
|---|---|
| Exon | join(1..273,723..1124,5576..6838) | mRNA Sequence | Download Select all |
| Length | 1955 |
CDS Information
| Location | join(144..273,723..1124,5576..6189) |
|---|---|
| CDS Sequence | Download Select all |
| CCDS ID | CCDS3180.1 |
Protein Information
| Protein ID | NP_002843.2 |
|---|---|
| Protein Name | Pentraxin-related gene, rapidly induced by IL-1 beta |
| Molecular Wt. (Da) | 40121 |
| Protein Sequence | Download Select all |
| Length | 381 |
| Uniprot ID | P04141 |
| Ensembl Protein ID | ENSP00000296871 |
Post-translational Modification Information (Source : HPRD)
No matching records could be found.
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
| Interactant Gene ID (Source: HPRD) | Gene Symbol | HPRD ID | Ref Seq ID | Technique | References |
|---|---|---|---|---|---|
| 712 | C1QA | 393 | NP_057075.1 | in vitro;in vivo | 12645945 |
| 713 | C1QB | 394 | NP_000482.3 | in vitro | 12645945 |
| 714 | C1QC | 395 | NP_758957.2 | in vitro | 12645945 |
| 2247 | FGF2 | 622 | NP_001997.5 | in vitro | 16020751 |
| 3075 | CFH | 601 | NP_000177.2 | in vitro | 19050261 |
Pathway Information
No matching records could be found.
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| cd00152 | 179-380 | PTX |
| cl22861 | 179-380 | LamG superfamily |
| smart00159 | 175-381 | PTX |
| pfam00354 | 182-377 | Pentaxin |
| pfam13385 | 206-349 | Laminin_G_3 |
| smart00560 | 264-345 | LamGL |
| pfam02210 | 223-311 | Laminin_G_2 |
| cd00110 | 223-311 | LamG |
| pfam11445 | 85-156 | DUF2894 |
| cl12969 | 85-156 | DUF2894 superfamily |
| COG3281 | 81-167 | Ble |
| cl21453 | 81-167 | PKc_like superfamily |
| pfam11740 | 85-165 | KfrA_N |
| cl13226 | 85-165 | KfrA_N superfamily |
| pfam05235 | 67-177 | CHAD |
| cl10506 | 67-177 | CHAD superfamily |
| pfam07201 | 70-207 | HrpJ |
| cl15454 | 70-207 | HrpJ superfamily |
| TIGR02680 | 63-182 | TIGR02680 |
| pfam13514 | 69-166 | AAA_27 |
| PRK09039 | 82-168 | PRK09039 |
| TIGR02169 | 81-157 | SMC_prok_A |
| TIGR02168 | 65-168 | SMC_prok_B |
| pfam13779 | 81-158 | DUF4175 |
| TIGR02169 | 69-196 | SMC_prok_A |
| pfam13514 | 64-183 | AAA_27 |
| pfam13514 | 62-174 | AAA_27 |
| TIGR02680 | 79-177 | TIGR02680 |
| pfam15450 | 58-158 | DUF4631 |
| pfam12128 | 65-167 | DUF3584 |
Ontology Information
| HPRD ID | 470 |
|---|---|
| Molecular Class | Secreted polypeptide |
| Molecular Function | Receptor signaling complex scaffold activity (GO:0030159) |
| Biological Process | Cell communication (GO:0007154); Signal transduction (GO:0007165) |
Drug Information
No matching records could be found.