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General Information



Gene_Symbol Gene_ID Gene_Name Chromosome Alias
CXCL16 58191 chemokine (C-X-C motif) ligand 16  17SR-PSOX, CXCLG16, SRPSOX 







  • Evidence
  • Gene
  • mRNA
  • CDS
  • Protein
  • PTM
  • Enzyme
  • PPi
  • Pathway
  • Structural
  • Domain
  • Ontology
  • SNP
  • Drug
  • External Links



Evidence Information


Pubmed ID Year Sample Information Techniques Mechanism Fold Change Remark
17510400   2007Cell line : -

Source : Toyama University Hospital

Sample Type : CRC tumor, normal tissue and blood plasma

No. of Sample : 58

Stage : -

Reverse transcription-PCR,ELISA, ImmunohistochemistryUp-regulation-CXCL16 is a new prognostic biomarker and may be useful for the development of a more effective therapeutic strategy for CRC.

CXCL16 expression was consistently up-regulated more in tumor tissues than in normal mucosa derived from the same CRC patients.


Gene Details



Chromosome 17 - NC_000017.11(4733529..4739928, complement)

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Gene Type protein coding
Gene Family Endogenous ligands
Description -  
Chromosome 17
Location 17p13
Start 4733529  
End 4739928  
Strand -  
Gene Sequence

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Length 6400  
OMIM ID 605398   
HGNC ID HGNC:16642   
Unigene ID Hs.745037   
Ensembl ID ENSG00000161921   
PharmGKB ID -   

mRNA Information


mRNA ID NM_001305000.1
Exon complement(<6319..>6400)  
mRNA Sequence

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Length 1466  



CDS Information


   
Location join(533..668,1009..1147,1439..1521,4421..4837,5277..5323)
CDS Sequence

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CCDS ID CCDS11052.1



Protein Information


      
Protein IDNP_001094282.1
Protein Namechemokine (C-X-C motif) ligand 16
Molecular Wt. (Da)24405
Protein Sequence

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Length 273  
Uniprot IDP48357
Ensembl Protein ID ENSP00000340884  



Post-translational Modification Information (Source : HPRD)


No matching records could be found.

Enzyme Information


No matching records could be found.

PPi Information


(Click to view network : Source STRING)      View   

               
Interactant Gene ID (Source: HPRD) Gene Symbol HPRD ID Ref Seq ID Technique References
10663CXCR65520NP_006555.1in vitro;in vivo1   101   710   011   290   790   


Pathway Information


            
Pathway Name Pathway ID
Chemokine signaling pathway hsa04062
Cytokine-cytokine receptor interaction hsa04060


Structure Information


No matching records could be found.

Domain Information


No matching records could be found.

Ontology Information


   
HPRD ID1090
Molecular ClassAdhesion molecule
Molecular FunctionTranscription regulator activity (GO:0030528)
Biological ProcessRegulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism (GO:0019219)  



SNP Information


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Drug Information


No matching records could be found.

External Links


                                 
ArrayExpressGO
ICGCGO
Cancer3DGO
COSMICGO
NCGGO
TSGeneGO
Tumor Gene Family of DatabasesGO
CCDBGO
G2SBCGO
Osteosarcoma DatabaseGO
RCDBGO