CoReCG

Search results:

General Information

Gene_Symbol	Gene_ID	Gene_Name	Chromosome	Alias
PWP2	5822	PWP2 periodic tryptophan protein homolog (yeast)	21	UTP1; PWP2H; EHOC-17

Evidence
Gene
mRNA
CDS
Protein
PTM
Enzyme
PPi
Pathway
Structural
Domain
Ontology
SNP
Drug
External Links

Evidence Information

Pubmed ID	Year	Sample Information	Techniques	Mechanism	Fold Change	Remark
20089989	2010	Cell line : - Source : VU University Medical Center, Amsterdam, The Netherlands. Sample Type : CRC tumor and normal tissue No. of Sample : - Stage : -	Biochemical isolation to nano-LC-MS/MS analysis	Unknown	-	-

Gene Details

Chromosome: 21; NC_000021.8 (45527208..45551063)
View Larger Image

Gene Type	protein coding
Gene Family	WD repeat domain containing
Description	-
Chromosome	21
Location	21q22.3
Start	44107290
End	44131181
Strand	+
Gene Sequence	>gi\|568815577:44107290-44131181 Homo sapiens chromosome 21, GRCh38.p2 Primary Assembly GCGCTGTGGGCGGTGCACGCCGTCGCTTCCCGGAAGTGCGTGCTGTGGGCGGTGCCGCGCGGACCCCCGG GAAGTGTCTCTGTGGGCGGCCGCCGGGTTGAGCTGCGGCACACGTGCGACGGCCGTGATGAAGTTCGCTT ACCGGGTGAGCGCGGGCGGCGGGCGGTCTGTTGGATCGGCGCGGCTCTTCCGGTGGACGGCGCCTGAGCT GGCTCCGGGCGGGCTGGGGGCGCGTGGTCTGCTTTTGCGGCGTCTGGCCGCGTGGGGGTCGCCGGCTGTC TGCGCGCCCGTGGCCTCGGGGACGCGGGGCTGTGGTGGGGCTCCTGGGAGAGCTGGGACGGAGGCGCCGA CGGCTTCTCGGAGGGAACAGGGACATTTGTCGGGGTCCCGGGATATTTTTAACCTGAGTATGGCCCAACC TAAAGGCTGGAGTTGGTGCAGTCGGGGAGGGCACAGCACCCTCGGGAGGGATGAGGAGGTGGGACGGGGC GGGGACGCGGGCGCGCGCAGGCGGGGTGAGAACAGCAGGGACCCGGGGCCCGGGACTGGTCCCTAACGAG CGAGCGTCCAGGTGAGCGGAAGGGCGGGGAACCCAGGTGTGAGCTCTGTTTCCCGAGGCCGGAGGGAATT CCTGAGGCGGACGCCCTCAGCTTTGAGAGCCAGGGAAGACTTGTCCCAGATGTGAAGTGCAGGAGGCGGG TGAGACAGGTAATAAGAGGGGGCCGTGGAGCCGGCCTGGGGGTCTCTGAAGCGTTTGCTACAGCTGGCCG GTTATGGGGACGCCTGTGTTTCCCACAGTGGCCCTGACCGTTGCGCTTCCAGGGTTGCACGGGCCGCCTG CTGCTGAGCCCACCGTGTACTACACTTGTCCTGTCCGAAACTGGGCATGGTACTGGCCCCTCAGAGTGCT GCTCCTGTGTCCCCTGTGCTGGTGGAGCCACCGCTGTGTGCCCAGCACCAAACCAGAAACCATATCCACG TCCTCACAGGCCAGGACTTCATCCGCTCCACATTCCTACTGCAAGGTGGCAAAAAATGTGCCTTGGAGCC TGCCTGGCCGCTTAAAGTCCTTCTGCTGACCAAGCTCCTCCCTGAGGTCCTGAGGGCGCTGCCCACTCAC AGCTTCAGGGCCTGGCTGGTGCCTTCCCATTTAGATTCCAGCTCAGGTGACCCTTCCAGGTGCCTCTCCG TGACCACCGTCTAAAGTAGCCCCTGCTCCCACACTTCTCATCCCCCTCCTGCTAGAGAGAGAATATAAGG TGTGCGTGTCTGTGCGCATGGCAGTCTCCAGTGAACGCTCGTGCTCGTGAGTTAGTAAATAGGATGCTGG CTTACCACACTTCTGGAAGCCCTGAGTTCTAAGCACTTTTGGGGTGCTGTTCCATTGTTGCAGCTTTTTT CTTGGTGAAGTGTGGGCTCCATGCCCCTCTTCACCTGGCAGACGCCTCCTGTCTTGGGAGGCTTCCTCAG TGCTCACAGGGGCATCTTACCCATCTCTGTGGGAGCTTGGGGCCGCCCGGGCTCCTCTGGTCTCCTGAGG ATCAGGCTCACTTCTTCCTCTCTTACCCAGGAAAGGTGAACGGGCCCCCAAGGTGGGGTTCTCTATGCCA TCTCTCTGCCCAGATGCCTCACTTAGTGCTTTTCTGGGAGTCGACTGTTTTCTTTGTGTTAAGACAATTT TGTTTTCTTCACAGTTTTCAAATTTGCTGGGTACGGTGTACCGGCGTGGGAACCTAAATTTTACCTGCGA TGGAAATTCAGTTATCAGTCCCGTGGGCAATAGAGTCACTGTATTTGACCTTAAAAAGTAAGTATGTGAA AGTGGTATTCATAATAGTGATACTGATTACTATTATCACCATTTTTTAAGTAACATATGAAAACTGATAG TGTCTTCTGTGCCTTCCTTTTAATGGTGCACCCGTTAATTAAGGGAGCCCAGGACAGGACTACAGGACAG ACTAGGGTCAGCAGATCAGTTGTGGAAATTGGCAGCCAGACCCAGTTCTTCGTTGTAGTGCCTTAGCCAG GCCCCATAAAGTGGTGTGTCACTTGGCTCCGTTCTGTGGGAAGGGACCCTGTCCCTGTGCTGTGAAGGGT GGGTGGGGGAAAAGGTGTAGCTCAGGGTTAGCCCTTCCCCCATCAGGGAAGGCCCCTAAGGGCTGAAAGG CCAGGGCTGCTGGGGGAGTTGAAGGTACCTTGGACCCCTGCTCGGGAGCCCTGCTGCCACTGGGCCTCAC CAGTCGGACGGGCAGGCCCAAAGCTTCCAGCTCTGCAGCCGGAGGTCAGTTTTATTCGCTGGGGTTTAGC GGTTTCTTCCTGTGTGCTGTTGCACTTTGCTTCACTTTGTTGCACTCTGGCTCTGTGCGGATGCTGTTTT ACCACGAAGCGAAGGTGTGTGGAAACACTGCTTGGAGAAAGTTGGTCGGTGCCATTTTTCCAGCAGTGGG GGCTCACTTCATGTCTCTGTGTCACATTTTGGTAATTTTGTGATATTTCAAAGTTTATTATACCTGTGAG GGTGATTTGTGATCATCTTTGCTGTTGCTATCGTGATTGTTCTGGGGTGCCGTGATCCGTGCCCATGTAA GACAGCGAGCTTAATCGGTAAGCACTGTGTGTGCTGTGCCTGCTCCACCGACCGGCTGTTCCCCACCCCC CCACGTCTCTCTTCCTCTACTTGGGTCTCCCTATTCCCTGACACAAACAATGCTGAAATTAGGCCAGTTA ATAATGGCCTACAGTGGCCACTACGTGTTCATGTGAAAGGAAGAGTCACACAACTCTCACCTGAAATCAG AAGCTAGAAGGGACTCAGCTTAGTGAGGAAGGCATGTCAAAAGCTGAAATAGGCCAAAAGCCAGGTCTCT GCCACCAAACAGGCAAGTTGTGAATGCAAAGAAAAAGCTTTTGAAGGAAATTAAAAGTGCTACTCCAGTG AACACACAAATTACAAGAAAGCCAAAATAGCCTTATTGCAGATACGGATAAAAGTTTGAGTGATCCAGAT AGAAGATCAAACCAGCCACAACATTCCTTTAAGCAAGTCAAAGCCTAATGCACAGCAAGGCCCTACCTGT CCTCTGTTCTGTGAGGGCTGAGGTGAGGAAGCTGCAGGAAAGAAGTTGGAAGCTAGCAGAGGTTGGTTCA TGAAGTTTAAGGAAAGAAGCCATCTCTACAACATAAAAGTGCAAAGCGAAGCAGCAAGTGCTATGGAGAA GCTGCAGGAAGTTATCCAGAAGATCTAGCTGAGATCATTGATGAAGCTGACTACACTAAACACAAAATTT CAATGGAGACAAAACAGCCTTCTATTGGAAAAAGATGGCCAGGCGCAGTGGCTCATGCCTGTAATCCCAA CACTTTGGGAAGCCAAGGTAGGCAGATCATTTGAGGCCAGGAGCTTGAGACCAGCCTGGCCAATATGGTG AAACCCCGTCTCTACTAAAAGTACAAAAATTAGCCAGGCATGGTGGCACATTCCTGTAATGCCAGCTACT CAGGAGGCTGAGGTGGAAGAATTGCTGGAACCTGGGAAGCAGAGGTTGCAGTGAGCTGAGATCGTGCCAG TACACTCCAGCCTGGGCAACAGAGCAAGACTCTATCTAAAAATAAATAAATTAAAAAAAAAGAAAAAGAT GCCATCGAGGACTTACATAGCTAGAGAAAAGTCAGTGTCTGGCTTCAAACAACAGGCTGACTCTCTTATT AGGGGCTAATGCAGCTGGGGCCATTAAGTTGAAGCCAGTGCTAATTCACTGTTCTGAAAATCCTAATGCC CTTCACAATGATGCCCAAGCTACTCTGCCTGTGCTCTATAAGTGGAACAGCAAAGTCTGGACGACAGCAC ATCTGTTTACAGCATGGTTTCCTGAATCTTTCCAGCCCATTGTTGAACCCACTAAGGTTCCTTTCAAAAT ATTTCTGCTGTTGGACAACGTACCTGGTCACCCATGAGCTCCAATGGAGACGCATAAGGAGATGCTGTCT TCATGCCTGCTAACACCACATCTCTTCTTCAGCCTACGGGAGTAACTTTAACTTTCAAGTCTTACCATTT AAGAAATATATTTTATAAGGCTCTAGCTGCCAAAGATAGTGATTCCTGTAATGGATCTGGGAAAAGCCAA TAAAAAGCTTTCTGGGAAGGAGTCGCCATTCTAGTTGTCATTTCATGATTCATTCAATGAGGGCAAAGTG TCGACATTAACAGGAGTCTGACAGAAGTTTAGTATCAAGCCTCATGGATGACTTTGAAGGGTTCGAGACT TTGGTGGAAGAAGTTACTGCAGATGCAGTAAAGATAGCAAGAGGATTCGAAATGAAAGCAGAGCCTGAAA TGGGACTGAATTGCCGCAATGTTGCCATCAATCTTGAATGAATGAGGAGCTGCTGCTTGTGGATGAGCAA AGCAAGTGGTTTCTTTTCTTTTTTTTGAGACAATGTCTCACTCTTGTCCCCCAGGCTGGAGTGCTATGGC ATGATCTTGGCTCACTGCAACCTCCACCTCCTGGGTTCAAGCAATTCTCCTGCCTCGGGCCCCCCTACCA AGTAGCTGGGATTACAGGCGCCTACCACCACGCCCAGCTAATTTTTGTATTTTTAGTAGAGAAGGAGTTT CATCATTGTTGGCCAGGCTGGTCTAGAACTCCTGACCTCAGGTGATCCACCCGCCTCAGCCTCCCAAAGT GCTGGGATTACAGGTGTGAGCCACCATGCCCGGCCAGCAAGTGGTTTCTTGAGATGGAATCTACTTCTGG TGAGGATGCTGTAAAGACTGTTGAAATGACAACAAAGGATTTAGAATATGACATCAACTTAGTTGATAAA ACGCTGGGAGCATTTGTGAGGATTGACTCCGGTTTTGAAAGAAGGTCTGTTGTGGGTAAAATGCTATCAA ACAGTATCACATGCTACAGAGACATCTTGTGAAAGGAAGAGTCCATCGATACGGCAAGCTTCACTGTTGT GTTAGGAATTGGCAACGGCCACCCCGTTTTCAGCAGCTGCCACTGTGCCTGGTCAGCAGCCATCCACATC GAGGCAGACTGTCTGCCAGCAAAAAGATGAAGACTCACTGAAGGCTCAGATGATTGTTAGCATTTTTTAG CAGTAAAGTGTTTTTAAATTAAGGGATGCACGTTGTTGCTTTAGACAGAATGCTTGTGCACACTGATAGA CTACAGCACACATGAGTAGACTGCAGCGCACACCAATAAAGTACACACTTCGACGACAGTACACACGAAC AGACTACAACTCACACGAATAGAGCACAGTGCACGCTTACAGACTACAGCACACGCTAGTAGACTACGCC GTACTGTTTACAGTATGGTGTAAACACAGCTCGGCTGCTTATGGGGAAGCTGGAATGTGTGTGCCTCACT CAGTTGCAGTGTAAGCGTTATCTGCAGCATCTCCGCGGGATTCCTGTAGCCCCTTATTTTCCATTTTTCT AGCAACAGTGTTACATGGGTGCACTGTCATGGTGGTTAATTCCTGTTGGGCACTTAGCTTGCTTCTGGTA TTTTGATGTCACACTGAGGCGGAATAATCCTCTCATCATATCATCCTGGAAGCAGAATTGATGTATCCAA AGCCCATTTTTAAGGCTTTTAATGCATTTCACTAGAGTTCCTCCAGGGACAACGTCATTTCTTTTTCTTT TTTTTTTTGAGACAGAGTCTTGCTCTGTCACCTAGGCTGGAGTGCAGTGGTGCGGTCCCAGCTCACTGCA ACCTCTGCCTCCCAGGTTCAAGCGATTCTCCTGCGTCAGCCTCTTGAGTAGCTGGTATTACAGGCGCCCA CCACCACGCCTGGCTAATTTTTTGGGTTTTTTTGTTTGTTTGTTTGTTTTGAGGCAGAGTCTTGCCCTGT CGCCCAGGCTGGAGTGCAGTGGTGCAACCTTGGCTCACTGCAAGCTACACCTCCCGGGTTTACGCCATTC TCCTGCCTCAGCCTCCTGAATAGCCGGGACTACAGGCGCCCGCCACCACACCCGGCTAATTTTTTGTATT TTTAGTAAAGACGGGGTTTCACCGTGTTAGTGAGGATGGTCTCAATCTCCTGACCTCGTGATCCGCCCGC CTTGGCCTCTCAAAGTGCCGGGATTACAGGTGTGAGCCACCGCGCCTGTCCAATTTTTTGTTTTTTGTTT TTATAGTAGAGACGGGGTTTCACCATGTTGACCAGGCAGGTCTCGTACTCCTGACCTTATGATATGCCCG CCTTGGCCTCCCAAAGCACTAGGATTATAGGCGTGAGCCACCGTGCCCGGCCAACAATGTCATTTCTTTT TCAGGAGTGGGGGGTATCCACAGATGAGCTCTGGCTTGTGGGGTCCAGTAAGATTGGAGGCGCTACTTGG GGAGGGTGAGCCGCTGGTCCCAGGCCAGGCCTGGCCTGTCTCCCTCATGTGACTTGAGGACCAACAGCAC ACTGTGGTTTTTGTCTTTATCAGCAACAAATCTGACACGCTGCCCCTGGCCACTCGGTACAACGTCAAGT GCGTGGGGCTGTCCCCGGATGGCCGCCTCGCTATCATCGTCGATGAAGGTACTTGCCCTTGATGTGGGCG GGTACTGAGGGGACCAGTGAGGAGGACTCAGGGCTGTGTGGGTCTGAAATGATCCGCTCCCCAGTCGCCT CCGTGTTGGGGCCCGGGTGGGGATTGGGGATGAGGGTGTCATGGGCGAGGCTGCGTCCCCGCCGCAGGCT GTGTCTGTGGCATCACCTGTGGCAGGGCAGGGCCTCATGGCCCTTGGGCATTCTCAGTCCTGACTCCTCA CAGTGGACGCGAGAAAGACCTTTCTCCGTTTTTCCCGTGCTATGTATCTGGGGTGGCCCCTGGGGTAGCT GCGCGGTGGTGACCTCTGGCGTCCTGCAGGGGGCGATGCGCTGCTGGTCAGCCTGGTCTGCAGGTCTGTG CTGCACCACTTCCACTTCAAGGGCTCTGTGCACAGTGTGTCCTTCTCCCCTGATGGCAGGTAAGGGGGAC AGCTTGGGGGCAGGAGGGTTCGGCCGTGCATGCCGACGGTGAGGCCCACTGCCCAGCTCGTTTCCCTGGG CCCCGGGTTGTGACGTTGGGTTGGGCACACGGCCCAAGCTCTGGCATTGGTGACCCCCTTTTCTGGAGGA GAAGGCTTGGTGCGGCCAGGCTGCCCTCCCTCCAGGGCTGTTTCTTCCCTGACTTTTGCTTCCTCTGCTC CTTGGCCTCCATCCTGCAGGAGGCGGGACTCCAGAAGGCCCAGGTGGGTGCAGGCTGAGACTCCACAGTG GCCTTAGGGCCATTGCTGGTCTTGAATATCAACTATGTCCGCGTTCCTTCCATAGGAAGTTTGTTGTCAC AAAGGGTAACATTGCCCAGATGTATCATGCCCCTGGGAAGAAGCGGGAGTTCAACGCCTTCGTTCTGGAC AAGACCTATTTTGGGCCCTACGATGAGACCACCTGCATCGACTGGACGGATGACTCCAGGTGCGGCCTCA GAGGCTTCGGGGGAGCGGGGCTTGAGAGAGGCCCCTTGGACAGGTCACCCCCTTGGGCCCTGCAGCTTCG TTCCGCAATGGCATCTCGGCCTCCTTTGGGGCTGGGCGCTGCCCACACCATCAGGACTGGCTGGGTGGCT GTGGTCGAGTCTTTGCGGCTCTGAAGTGTGTGCTGTGGCCGAGCCTCCTGCCCCTGCACTGCCCTTTCAC CTGTTTGTCCCAGAAACTGGGAATGCTGTGGTTGGCTCGGGCAGCGTCTGGGAGGAGTTAGGAAGGCAGA CAGGGCAGGGACAGCGTCTGGGAGGTGTGAGGAAGGCAGACAGGGCAGGGGCTGTGCCGGGGTGTCTTCC TGTGCCTGGAGGCGTCTCAGCTCACTCTGAGACCACGTGGGGCTGTAGCGGTCTCCGTGCAGCCCTCTGG AGCTTGCACCTGGCTGCTTTGTTATGGCCAAGCCCTGAGGAGGTGCCATCTCCCTCTTTTCCAGGTGCTT TGTGGTTGGGAGCAAAGACATGTCCACCTGGGTGTTCGGAGCCGAGCGCTGGGACAACCTCATCTACTAT GCACTGGGGGGACATAAGGATGCCATCGTGGCCTGCTTCTTTGAATCCAACAGCCTGGACGTATGTCCCT TTGCCAAGTTCCCTAGCCTGATGGTGGCCAAAAGCGGCTAGTTCAGGGAGGCCCCAGGCTGCAGGCGGCC TCTTCCTGCGGTTCCCCCAGGCTGTTCCCGTGTGGCCTGGGGGCATCTAGGGACCGATGGCAGCTGTGGC GGCCCATCGAGAATTGTTCTCAGAGTTCAGAGGGGCCGTCGGTGCCACTGGTCCCTGGATCTGAGCTGGA GGGAGGTGCCGGGTTGTGGCAGCTGGGCCAGTGTGGCTGGGGCTGGGGTGACCCTGTGCTTCCCCTTGCA GCTGTACTCACTCAGCCAGGACGGAGTGCTGTGCATGTGGCAGTGTGACACGCCCCCCGAGGGCTTGCGG CTGAAGCCCCCTGCGGGCTGGAAAGCAGACCTGTTGCAGCGGGAGGAGGAAGAGGAGGAGGAGGAGGACC AGGAGGGCGACAGAGAGACCACCATCCGGGGAAAAGCCACTCCGGCCGAGGAGGAGAAGACAGGAAAAGT GAAGTACTCACGGCTGGCCAAGTAGGTCTCTGAGGTGTGGTGGGCTGTGGCGGGGCACTCCTGTGGGAAT CTCTTGCCCCCAGAGGGATCTGGATGTGGGGTCCCCAGGGCCGAGGAGTGGGAGGTACAGAGAGCAGGCC TGCGTCTCAGGGCCCCGGTTTGAGCACCCTCGAGTGCTTGGGTGTTGACCCTGCCCCTTAAGCAGGGTCC CTGCCTCGGCTGTCTGAGCTGCCTGTGTGCCCAGGGCAGGGCAGAGGGCGGTGGGTAGGGGTGCATAGGG GGCAGGGAGGTGTGCGGGCACTCCGTGACGGGAATAGCAGCACCTTGGGCCCTAAGGGGGTTGGGAGTTG TCTGTGGCCCCACCAGCTTCTGTGGAGTTTGGTGTGGGCGATAGTCCCTTGGCCTCGTGCAGGGAGATGC CGGGAGAGCATTTGGCAAGGGTGGAGGGAGGGACCGGGCTGTGAGTGGGCGCAGCGAGTGGTCTGAGTCC TGCTTCGGGGCCCGCTGGTGGGTGGTACTTGGTGCTTTTTCAGGCACTGAGCTGGGCCGTGCAGCCCCGC ATCCGGACTCAGTCCCCCAGACGAGACGAGATGAGATGAGACTGAGCCCGGCCCCACGGACTGCCTGTGG GATGGCCTTAGCTGTGCCTGGAGCCCTGGCAGAGATGCTGCCCTGATTCGGGGTGTCCCGCGTCTGGGCT GTGGGGGGAGGCTGGTCAGGATCACATGAAGGCAGAGTTGCCCGCAGCTATGGTGTCTCCGTCACCCGGG TGCCCCAGCCTGGGCCCCTCCTTGCTGCAGTTGCTTAGCGCCTGCTGTGTGCAGGGCTCTGAACTTGGCA CTGAGACACACTGCCCACCCTTGTGAGGCCTCCTCTCCGCCGGGGAGGAGAGGTGCAGTGATGAGGTGGC TGCGTGCGGAGGTGGGCGGCAGTTGGGGTCCCTGGGTGGGGAAGGCGCCCACACAAGGCCCTGCCTGTGG AGGGAGCCAGGCGGCCAGAACGGGCTGCCTTTGGAGGGGTTGGGGTCTGCTGGGTAGGTGGGAGTTGTGG CCATGAGAGCCCTGGGTCTGAGGAGCAGGGAGGGCCGGCTGGACTCCAGTGGGAGGAGGGTGCTTTGCCA AGGGCAGCGGAGTTGGAGGGTGGCCAGAACAGGTCCAAGTGGGTCAGTGCCCACAAGTGAGTCAGTGCCC GCGGGTGGGTCAGTGCCCGTGAGTCCGTGCCCGTCAGTGCCCGCGGGGACTTGGGGGTGTTGTGCTGGAG TCAAGACTTGAATGGGGACTGGAGGAAGAGGAAGGGATGATGGGCCCCCCAACCCCGCCCTGGGGAAGGG AGGTTCCAGGCAGCTCCAGGAAGACAGTGTGCCTGCTAGGCGGGGACTGCGGGCTGTCAGCGCGAAACAT GTGAAGGGAGGGCCTGCTGCATTGGCAGCCAGTGCTCCCTGTCACTTGTTCAGGAGGGACGGGGTCCAGA AAGGAGAGGGAAGGACCAGGGCTGAGCTACAACGTGACTTGGGGAGGTTTTGAGGGCGGGGGTGCCATCA GGGTCACCTTCGTCTGCTGATGGGGACCGAGGGTTCCTTAGAGGAGGAAGCAGCAGGGGATGATGGGATT CGGGTGTGCCTGGCGGCCATGCCGCGCCTCCCGCACCTCCTCTGCCTCCCATGGGCACTGCTGTCTCTGG GTGCACCACTAGCTCTGCTGTGGGGCCAGCTGGCGACAGTGGAGATGCTGTGTGAGGTTCCTTTGGGGTC CCGAGCTTGGGATGGAGGCGGGCAGCTTCAGGGCCTGGGGTGGAGAGGGAGAGGGCAGGTCTGGGACCTC CTGCCTGGATCTGTGGCCTGTGTCCTGGAGCCCAGAGCAAGCTGGGGTGGCAGTCTGGCTCTGCGCTCCT CCTCACAACTCTTCTCTCTCGTCAATTCAGGTACTTCTTCAATAAAGAAGGGGATTTTAACAACCTGACA GCTGCAGCATTTCATAAGAAGTCTCACCTCTTGGTCACTGGCTTTGCTTCTGGAATCTTCCATCTTCATG AGCTGCCAGAGTTTAACCTCATCCACTCCCTGAGGTAAGCCTTTGCTCGCAGTGGGGTGTGGTTTTATGC ACTCACTGGCCCTGAATCTGAGGGCCCAGCCAAGCCTGCCCTTAGCAGTGGGGGCAGCAGAGCCACTTGG AGCGCCGGCTCAGGCCACAGGACGGCAGCCCGAAACCTGCCCGGCCGCTGGTGCTGGTCAGTGCGACAGT GTTGCCGCCCCCACTGGCAGTCAGCAGCATTGGTCTCGGGTCAGTCACAGCCTTTCAAGTTTTTGTCTCC GCTTTTCTTCATCTGTGAGACACAGAGAACGAAAATACTATGCTCATAAAATTGTGAAGTTGCAAGTTGT TGAACCCTGGCCTCCCCTCTGGGCCTTCTCTGATTCTTTTCTTTGAGACAGAGTCCTGCTCTGTCGCCCA GGCTGGAGTGCGGTGGCGTAATTCGGTTCACTGCAACCTCCGCCTCCCGGGCTCAAATGATCCTCCCACT TCAGCCTCCTGAGGAGCTGGGGCCACAGGTGTGCGCCACTACACCCGGCTAGTTTTTAAATTTTTTGTCG AGACGGGTCTTGCTGGGTTTTCCCAGCCTGGTCTTGAACTCCTGGGTTCAAGCAATCCTTGCCTCCGCCT CCCAATGTGCTGGGATGACAGGCGTGAGCCACTGCACCCAGCCCTCTGATACTTGAACTGAAGTGAATTG TTGGAGTCTGGTGAGTGGGTGGGGTAAGCTCTGCACACAGGGATAGAATCTGGTGTCTGGGGCTGCCCTG AGTGGGCACTGGGGCTTCAGCCCGGGCAGGCTGGCCTCCCACTTACAGGCCCGTTCTCTGCAGCATTTCA GATCAGAGCATCGCCTCAGTGGCCATCAATAGCTCGGGGGACTGGATTGCTTTTGGCTGTTCAGGTTTGT CCCCCGCCTGGGTGGTAGAGATGGACTCCCCATTAGGGACCAGTGCTGCCCGGCTACAGGCATACTTGAC AGCCACCCACTGGGGGTGCCCTCCCCTCCCCCAGTTGTCTTCCATGGGGTGCCCTCTCCCCCAGCCGCCT TTCAGAAGGGGCCCTCCCCTCCCCCAGCTGTCTGCCATGGGGTGCCCTCCCCTCCTCCAGCCACCTTTCA GGGGGTGCCTTCTTCTCTTCCAGCTGCCTCCCAGGGGTGCCCTTCCTGCTCTGGCCCTCCTCAAGCACCT CTCTGTCTTAAGCCCCTTGCTCAGGGGTCGGGGGTCATAGCCTGCCTCAGTTGTGACCTGCAACCACTGG GTTGCACGGGCGGGGCCCATCACTGGCTGGTGAAGCTGCAGCATCGGGCAGTGGTCCCAGCCTATGCTTG GGGGTTTGTGCGTTTCACCCCCTGCCCGGCAGCTTTCTCAGTCCTGTGCCAAGTGGGAAGGTGGGCCGGG CCAGTCTGACCTGGGGTGGGCCTGAGCCGGGTACCCCAGCTTCCCCCGTGTGCACAGGCCTGGGCCAGCT GCTGGTGTGGGAGTGGCAGAGTGAGTCCTACGTGCTCAAGCAGCAGGGCCACTTCAACAGCATGGTGGCC CTGGCCTACTCGCCCGACGGACAGTACATCGTGACTGGCGGGGACGACGGCAAGGTAGGCTCCTGTCCCC GTCCCGTTGGCCTCTGTGCCTGGGGGGCTGTGAAGATGCAGTGGTCTGTGGGGCCGTGTCTTGACGGTAG GGCTGGTGTTCACAGCTTCACCCGGGCTCATGAGCTCAGTAGGCGTTTAAAAACATACAAAAATGTGAAT GGAGAGGGTTGGGTGTCCCTCTTTCCCCTTTCTGACTTGGTCTCCTGCACGGTGGTGGCTGCGTGGCGGG GAGAGGGTCTGTGGTGCCGGCAGCCGGCATCCAGCCAGTGTCCAAGGGGCTCCAGTACGTGGCCGAGGGT GGGTCCATGGTACTGGCAGCTGGCATCCGGCCAGCATCCACAGGGTTCTGGTGTGTGCAGTGCCCCTGCG GGCCATCTAGGCCTTAAATGGGCTCCTCCTGGAGGTGACAGGAAGAGACTGGGGCAGACGGCCCACTCAC CACCCACTCAGCACAGCCTCAGGCCTGTTGGGGAGGCTGAGTGAGCCAGGGCAGCCGTGGGCACAGGGGC AAGGCTCTCAGGATGTGGCGTCACATGCGGGGGTCTCAGGGATGGGGTGTCAGTTGCAGGTGGGGGTCTC AGGGATGGGGTATCAGTCACAGTTGGGGGTCTCAGGGATGGGGTTTCAGTCATGTGCGGGGATCTCGGAT GGAGTGTCAGTCACAGTTGGGGGTCTCAGGGATGGGGTATTACTCACGGGTAGGGTCTCAGGGATGGGGC AGTACAGGGGCAAGCATCTTAGGTGGGGCGGCATGGGGACAGGGATCCTGGCCGAAGCCGTGGCACACAG GGTTGGGGTCTGCCCCCGCCCCTCCTGTCCTGCCTCAGGTCAAGGTGTGGAACACCCTCAGCGGCTTCTG CTTCGTCACTTTTACGGAGCACTCCAGCGGGGTGACCGGTGTGACCTTTACTGCCACCGGCTACGTTGTG GTGACCTCATCCATGGACGGGACCGTGCGAGCCTTTGACCTTCACAGGTGATGTTTTTGCTCCGGATTGG CTTGGGGCAGGCTTCCCCCACGCAGAGGTGAAGGTGGAGGGTGAGGCTGCAGTGCAGCTGCTGGGGCAGG GGACCCTGGCACGTGACTCTGACCTTGCCTCTTCTCTGCAGGTACCGAAACTTCCGCACCTTCACCTCTC CACGCCCCACCCAGTTCTCCTGTGTGGCGGTGGATGCGAGCGGTGAGATCGTCTCTGCAGGGGCGCAGGA CTCCTTTGAGATTTTCGTGTGGTCCATGCAGACAGGCAGGCTCCTTGATGTAAGCACCCTGAGGGGCTGG GCTGGGGCTCAGGAGGGGCCCTCCTGTCTCCTGGGAGAGGAGCGCAGGGAGCTGAGGTTACACTCCGAGG GCCCATGCCCCTGGCCCAGAGCTGCCCAGAGAGCCGCCTCGGCCGCCACCTCCACTCTTCACGCCTCCTT GCTCTACGGTAGGTTTTGTCTGGACACGAAGGGCCCATCAGTGGTCTGTGTTTTAACCCAATGAAGTCCG TCCTGGCCAGTGCCTCCTGGGACAAGACAGTGCGCCTATGGGACATGTTTGACAGCTGGAGGACCAAGGA GACGCTGGCCCTGACCTCTGATGGTGAGCACGAGGCAGCAGGCAGGAGCAGCGGCCTGGGGACCAGCAGC ATGCTGTCACACCCACTGCCCTGTTCCTCGTTGTGGGTTTGGTGTGAACCTTCTGGTGGGAAGCAGGGGG TGGCTTTTATCCAGACCTGCTGGTGTGGCAGCCCTTGAGGTTGGCAGTACCTAGGAGACAGCAGATTGGC GAGTCAGGCCAGCGTGGCTTCCACAAGTCCTTGTGGGGCTCCCGCTCTGTGGGCAAGTACGCCAGGCAGG AGAGAACAGCTCCCCGAGGGTGAAGGGCTGCTGCCGCAGCTGCTTCCTGATTTTCGGAGTTGCTTTGGAG CTCTGCCAGGGCTGTGTCACTGGGAGAAGGACACAGGGACCATGGGGGGCCCAGACGCTGGATGCGGCCA GTCCCGGAATCTGCAGACTGGGAGAAGGATGAGGGGGCCATAGGTGGGCCCGGAAGCCAGATGCGGCTGC CCAGGGATCTGCAGACTGGCCTCAGGCCACTGCCTGTCTTTCTGACGGGGCTGTACTAGAGGCAGCCGTG GCCTCCTGTGTTCATATGGTCTGTGGCTGTCAATGCCTCAGCGGCGGTGTTGAAAGACCACGTGGCTCAC AAAGACCCAGCCCATCCATGTCCGGGTGTGGACAGACTCTGCCATCCCAGGAGGCTGGTTCTCTCTGCTT CCCGCTGCCTCACCCCACCCCCAGGCCTGGCATTGGCCAGGCTTTTGGCATCACATGTGGCTTCTTTGCA GAGGCTCTGTATTCTAGTCTGTCCAGCCGCCCTCAGTAACCACCATCACTCACCCATCAGCCTCACCTTC CCAGCGCCCCCTCCATCGGCCTTTGTGGGTCCTGTGGCCCCAGCTGGACCGCCTGGTGCTCTTCACTGGC GCTGAGTTGTTCCTCACCTGTCTGGGTTGGAGCTTCTCCTGGGAGGAGATTCTTGTGTACCAGACCAAAC AGGCGCTGGTCTCTTAGGGGTGCCAGGGCACGGCCTGGTCTCCAGCCAAGGGTGGTTGGTGGCCTGCCTG CGGGAGACTGGGGTCTTCGTTGGGCCTTACTTTGCATCTCTGTTTAGCTCTGGCTGTGACTTTTCGCCCT GATGGTGCGGAGCTGGCTGTGGCCACACTGAACTCACAGATCACCTTCTGGGACCCTGAGAACGCGGTGC AGACGGGCTCCATTGAGGGCAGGCATGACCTCAAGACTGGCAGGAAGGAGCTGGACAAGATTACAGCCAA GCACGCGGCCAAGGGGAAGTGAGTGTCAGCATCGGGCCTCCTGATTTGAGACCCCAGCCAGCCACCAGGC TCCTGCAGCTTCTCCATTTTTGGCCTTGTTCTTTGTTCCTGAGACCGCTGAGTCCCTGTGGGTGGAGGCA GGTGGTCCTGAGCCCTCTGGGGAGAGTCCATGTCCTCCTTAACTCCTGGGATCGCACAGCCCCCAGCACA GGAGGACGTCTGGATTTACTGAACATAAACTTGTTCAGCTGAGAGCTTGCATCCACTTCCAAACCTTGAT CCTGAATTATGACATCGTCCTGGTGTGCAGAGGGGAGAGCAGCCGGGTGCCCGAGCTCACACTGGAGACC TGGCACTTGGGGAGGCTGAGGCGGGTGGTTTGCTTGAGCCCAGAAGTTTGAGACCAGCCTGGGCTACGTG GCAAAATGCCATCTCTACAAAAAGTAGAAAAATTAGCCAGGTGTGGTGGCACATGTCTGTGGTCCTAGCT AGTCGGGAAGCTGAGGCAGGAGGATCGCTTGAACCCGGGAGGTCAAGGCTGTAGTGAGGATGGCGTCATG CCATTGCACTCCAGCCTGGGTGCTAGAGCAAGACCCTGTCTCAAAAACAAAACAAACAAAAGCAGAAAAC AGCCCTGGCAGCCTCCTAAGAGTAAAAATGCAGGTCCTCAGTCACCTCACTTGACTAGAGAGTGCTACGT GGATGGTGAAGACATAGTGTCCCCTTGTCTCAAGGAGTCGGGCCAGCACAGCACTGACCAAATTGCCTGC GCGGGGTCCTGGCTGGGCTGTGAGGCTCAACTGGGTGGGGGTCAGGCTTAGGAGAAGGGGGAGGATCTGT GGGATGTGCCCGGGGTGGGTGGCCTTGGGGGCTGGACCTGTGTCCCAGGAGCTCAGAACCTGTTCAGCAG AAGGTCTTCCTCCAGAAAGAAGTAGCGACCCTGTCTTGGAAGTGGTATGAATGCCTGTGTGCAGTCCTCA TGGGTTCGCCCTGAGTGTGGAACTGCTGGGTGCTGGTGGTTCTGTTTCCAGCTTGGAGGAGCTGCACGGT TGCCATTCCCACGAGGAACGCTGTCGGCTTCTGGCTTCTCCACCTCCTCGCCAGCACTTGTTGCTTTATT ATTATTATTTTTTTAATGAGAGCTGTTGGGGTGGATGTGAATTCGTATCTCATTGTAGTTGTGATTGTGG TTTCTCTAGTGACATTCAGCATTTTCTGTCTGCGGCTTGGCCGTTTGTAAGTCTTCTTTGGAGAAGTGTC TGTTCAGGTCTCTTGCCTGTTTTTGAATTGGGTTGTTTGGATTTTGGTTGTGGATTTTAGGGGTTTCTCT GATACCTGATGTGCAGATATTTGTTCCGCTTTGTGAACTGTCTTTCCACCGTTTTGGTGGCACTCTTAGT TCTGATGATGTCCACTTTGCTCATTTTTTCTGTTGTTCTTTGTTCTCTACTGTCATAACTAAGGGACCTT GCCCACCCCGAGGCGTCTGTTGAGCGGGGTGGTAAGGGCTGGTTTCTGGTTTCTGCAGGACTAAGCAGAC GTGACTGAGAGTAGGCTGCTTAGGGTGGAGGCCGACTGGTCGCCGTTTTGTGCTGACCTCAGCAGGGAAC ACTGTTCCTTGAGCCACTTGTTCCTTTTGTGAAAAAGACATTGATTCTCAGGAAGCGGAAGCATCTAAGG GTGGTGCTGGCTCAGAGCGGAACCAGGTGATGGCACCATTGGACATTGTGGGTTTTAAAAGTCTCGCGTG AGTTGAGGCAGCGAGCCTTGGCGAAAGTTGCTGAGGCTGGTGTTTGCTTCCTGGAGGGCTGGTATAGGAT CTCCTCTATTTCCTAAGGTTAGTTTTTATTTTATTTATTTTTATTTTTATTTTTATTTTTGATTTTTGAC ACGGTCTCGCTCTTGTCACCCAGGCTAGAGTACAGGAGTGCAATCATGGCTCACTGCAGCCTCCAACCCC TGGGCTCAAGTGATCCTCCCACATCAGCCTCCTGAGTAGCTGGGACTACAGGCATGTGCCACCGCACCCT GTTAATTTTATTTTTTGTAGAAACAGGGTCTTGGTATATTGTCCAAGCTTGTCTTGAACTCCTGGACTCA AGCAATCTTCCCAACTCAGCCTCCCAAAGTGCTGAGATAACAGGCGGGAGCCACCATGCAGGCCTAAAGT TGGTTTTTAGGAGCCATACGCTGAGGTTTCCGTGGTGGCCACCGTAAGTCCATGTCTCCTCTCCACCCAG GGCCTTCACCGCCCTGTGCTACTCTGCAGACGGCCACAGCATCCTGGCGGGAGGCATGTCCAAGTTCGTG TGCATCTACCACGTCCGTGAGCAGATTCTCATGAAGAGGTTCGAGATCTCTTGCAACCTGTCTTTGGACG CCATGGAGGTGAGCCGCCAGCGCGGGGCCGGATGGATGTTGCTTCCAATGCAGGTGGAATGCGTCGGGCT CCTGCGTTCTGCACTCCTGGCTCCATGGGGCCTTGGGCACAGTTGTGGTGCTTGTCCTGTATCTAAGTGC ACGGGCCCCTCACCTGCCCCAGCAGAGTCCGGCCGTGAAGCCAGCACCTGCCTCAGCTGTGTGTGGAGCC ACGGTCCCCAACCCTTTTGGCATTTGGGACCGGTTTCGTGGAAGGCAATTTTTCCACAGACAGGGTTGGG GGGATTGATTTTGGGATGAAACTGTTTCACCTCAGATCAAGATCACCAGGCATTAGATTCTCAGAAGGAG GGTGCAACCTAGATCCCTCACGTGTCGTTCACAATAGGGTTCGCACTCCTGTGAGAATCTAATGCTGCCA CTGATCTGTCAGGAGGCGGAGCTCAGGTGGTGATGCGAGCAATGGGGAGCGGCTGTAAATTCAGATGAAG CTTCACTCATTCACCTGCCCACCACTCACCTCCTGCCGTGCAGCCTGTTTCCTAACAGACCATGGGCCAG TACCAGGGGTTGGGAACCACTGCTGTGGATGACCCTGCCGAGGCTGGTTGCTAGGAGGCTGGAGCTGTGA GGGGCAGTGCCCAGCACACGCTGGCTCAGGAGACACGGACATCTGTCAGGGAAGGAGTGAACGAAGAGGG TGCTGGTAGGCCCTGCCCGATGGCTTCCTGCCCGGGGTCCTGTGTACAAGGCTCTGCCTTCACTGTCCCC ACTGGTGCCTGCCCTTCCCCCTCAGCACAGCCCTCGGCTCAGGTCCCACTCACATGCTGGCTCCTGCAGG ACCTCAGAATGAGAGTGAGGAAGCCCTGGTAGCCTCTAAGCAGGGGTGTGGCTGCTGGGTTCACCTGTCC ACGCCCCATCGGGGCAGAAGCCCACTGTCCCCTAAATGTTTCTGGGGGAAAGTGTCCTTGGCATTTTCAC AAGGGAGTAGACGGCCATCCTCGCTGTGAGCCCCAGCCTTTGTGATGGTGGCAGCAATGCCAGCATGTAG ACCTCAGTCCATCCCCCTCCGCAGCCTCCGCACCTGCCCTGCTCCACAGCTTCCACACCCACCCTGTCTG CAGCTAGCTCTGCAGGAAGAGTCCCTGGGGCACTGCAGGGCTCTCTCCCCGTCCTTGTTCTAGACAGGGC TGAGGCTTGTCTGGTGTTGGGGTCAAAGAGCAAGGGTAGGAGACGAGGGCCAGGCGGCCAGGCCATCAGA AGCAAGGCGTCCACTGCTTTTGCTGTTCTAGGAATTTTTGAACCGAAGAAAAATGACAGAGTTTGGCAAC CTGGCACTAATTGATCAGGATGCTGGGCAGGAGGATGGAGTCGCGATACCACTGCCAGGCGTCAGGAAAG GTGAGCAGAGGTTCCTCCCGCATCTGCCCACCACTCACCGGTCCTGGGTGACCACGCATTCATGCCCCTG GTTGGGGCTGCAGTGTGTGGAAATAACAGTTACTACATGGTGACATTTGCTGGACACTGGGGGTGTCAAA GGCCCAGTGGGTTGGTGCTGGTGCCGTCAGCCCCTGGGCAGGAGAAGCTGCCCATGTGTTGCTACACGTG GCCTCCCTGCCCTGGCGGGACCCGTCCATTTGCTCTTGGGACTGGGTGCCCCGTCTGCTGCACAGCACAC GGAGCATTCTGGCGTGAGGCCATGTGCGCCGCACAGAGAGCCAGGTGCTCTAGAAGATCTGGGTCCCAGG TAGACCATCCTGATGGGACACTCGCCAGCCAGAAACCCTGAGTGCTTCCATATGCAGGCCCAGGGTACCG TGTTGAGCACAGCAGACCCACTCCTGGGCTGGGCTGGGGCCCTTTTCTGGGTTGGACACACAGTCTGCTG GCCGGGCTGGCTTTTTTGAGCATCTGCCCCATGGGCTGGGCCATCTGTTTGGCAGCTCACCCGGAACAGC CTCCGCGGCCCCAGCACGGGCCCACCTGCCGCAGCTGCAGCGAGGGAAGGGCTGCTTCTGCCTCCGCTTT GTGCAGGACCCAATGAGTAGAGGCTGCTGCTCTTGATGGGGCTCCCACAGCACCCCCCAGCCAGCCGGGA GACCGCAGGATGACTTGCTTCGTGGGGAGAGCAGCCTGGATATGCTGTCCAGTGATCATTAACGGTTCTT TTTTCCCCAGGTGACATGAGTTCTCGGCACTTCAAACCTGAGATCAGGGTGACCTCACTCCGCTTCTCTC CCACTGGTGAGCACTGAGCCATGGGCTTTTGGTGCCGGTGGGCACTGGGGCATCTGTGCCATAGCAAGGC TGGCCACCATGGAGCTGTCTGCAGGCTCTGGGCTGTGCCCTGTGCCCCTGGGTAAGAACATGGCCCTGCA AACCCTGCAGGCCACAAGATGGCTGTTGTCCCTGAGGATGGATGGCTGTCACGGTGCCAACCTCAGATGC ACTGAGCTTTGAAACATGGCAGGCCTGGTATGCCCTTGCTCTAGCAGCTCCCCGAGTGCCCTGGACGTGC TGCCTGGGGGCGGCTCTGCCATCACGGAGAGCCCGTCTCCTGCGCACTGCCCCCATCCTCTCGCAGTGGG GAGGAGGGTCTGTGCCACAGGCCTGTGGAGCCTGGCGGTGCACATGGTCCCCACACAGAGGAGCCAGGAG CAGGGCTATTGGCAAGCGTGCTCCAGCCTAGACTGAGTGTCAGAGCCAGGGGCAGAGAGGCCCATGTGAG CCAGGGGTCTGTGCCCTCGGGCCCAAGGGCCAAATCTGGCTGGCCACCTGCTTTGGTCACTGATGTTTTA CTGGGACATTTTACTGGGCGTTTTTTTGTTGGCGGATCCTTCTGGCTGTCTCTAGTGATCCGTGCAGCAC TGAGTAGGTGCAGCAGAGACCACAGGGCCTGCGGAGCTGAAGACGCCTGAGCTAGACAGAAGACTTGGCT GGCTCCCGGCGTCAAGAGAGGAGGACGCATGCGTGTACATATTTGCTTATATGTGCATCCCTGGGAGAGT AACTTCTGGGATGATCCATTCATTCCTTCCCAGGGGAGTAGTGGGGTGGGGGCTAGAGGCAGACGTCCCG GTTCCTCCTGATTTTTGCACTTTGTCCCAGGGGAATGTACTTAATACTGTTTCTTTAAAAAAAAAAAAAA AGAAAAAAAATGTTGGGAGGAATGAGCTTAAATTTTTAGGAAAGCACTGCTTAATTTCCCAGGGCGCTGC TGGGCGGCCACCACCACGGAGGGACTCCTCATCTACTCCCTGGACACCCGCGTGCTCTTTGACCCGTTTG AGCTGGACACCAGCGTCACCCCCGGGAGGGTGCGCGAGGCACTGCGCCAGCAGGACTTCACCAGGGCCAT CCTCATGGCCCTCCGGCTCAACGAGAGCAAACTGGTGCAGGAGGCCCTGGAGGCGGTGCCCAGGGGCGAG AGTGAGTTGGGGCTTCGGTGTCGGGCGCCGGGGTCATCCTCTCTTCCCCTGGTTTGAGTTGGTGGCAGAA TAAGCATGATTTTTTCTCCTTTTGCAGTTGAAGTGGTCACCTCCTCCCTTCCTGAACTGTATGTGGAGAA AGTGCTGGAGTTTTTAGCTTCCTCCTTTGAAGTGTCTCGCCACCTGGAATTCTACCTCCTCTGGACTCAC AAACTGCTCATGTTGCACGGACAGAAGCTGAAGTCCAGGTAGAGGGTCTCCCCCGCAGTTCATCGGTGGC TCAGGTCACTGGACCAGCTTGTCCTGCTGGATAAAAGGGAACTTTGACATGCCAATGCAGCATGAAGTGA GCCCACTGTACCACGGGGTGAGCCCCGCACGCTTAGGGAGTCTCCCTTTCAGAGCCGGGACGCTGCTGCC TGTCATTCAGTTCCTCCAGAAGAGCATCCAGCGGCACCTGGACGACCTGTCGAAACTGTACGTGTGGGTG CAGGGCCTGGGGGTGGGTGGGGTGCACGGTCCCCTGCTGGTCCACACTGTGGAGTGCTCCTTGTGTCATC TGATTTGAGGACAAAAGGAACCAGTGCTGGAGGCTTGTCTTCTCACCTGCGGGTGAACTGCACCTGCCCG GCCACCCCGTGGTTGAGCAGCTTGGGAAATGGCCTGGCGCTGAATGGAAAGCAGTGAGCACTGTGGCAGG CAGACAGGCTGCAGGTGGCGCGCTCCAGGTGCGGCCGGAATCCTCCAGGCTCTTGGAGGGATTGCCGCAT TCGTAGGACCAGGCAGCCTTTCCTGAATTTGCAGGTCACTTGCACAGGCAGTGGGGGTGGTCACAGGACT GTGAGGCCAGGCAGCCTGGAGTCCTGGAGGTGTGGCTGCCCTGAGCTGTGGCTCCCCTAGAAAAGGGTGC TGTTGCTGCTGCTGCGAGGATTCATCCGCGGGCCTAGGACAGGGCCTGGCCCTCCGCAGTGCTCACTCTG CAGGGGTGCCCGCCTCTTCTCCTGTCATTTCTTTGTGGTTTGTGCCTTTTTTGTCCCTACCAATTCACCT TCCCTAAAGGTCCTGCAGAGCCGGGACTAGGCAGGCCTCAGAGTAGCCATGTGAGGGATATCACCCTCTG TTGCCAATCAGTTGCCGGGTTTCCCAGCTGCGTTTCTGAACGGTCTGTTCTCTGTCCTGTTTGCGAGTTG CTCTGTCCAGGGTTCAGGGGCAGAGCCTGAGTTTGGGCCTTGTGGGTTCATGTGGTCCTCCTGTCTGTCC TTGAAGTGTCACTCAGTCTTTGGAAAGAGTCCTGGAGTCCAGGTCGAGCCTGTCCTCCCCTCGTGTTCTG GGTGCCCTACAGAAGGCTGGGATGTGCCCTGATCCACAGTTTTGGTGCCAGGCCTTCCCTCGGCTGAGAT GTCCTGGACTTTTCACAGAGCTCTGTAGGGGAGGAGGGTTGTCTAGCTCCCTTATTTATGTATTTATTTA TTTTTTAATTCATTATTATTATTATTATTATTTGAGATGAAGTCTCGCTCTGTTGCTTAGGCTGGAGTGC AGTGGCGTGATCTCGGCACATTGCAACCTCTGCCTCCCAGGTTCAAGCAATTCTCCTGCCTCAGCCTCCC AAGTAGCTGTGGTTACAGGCACACGCCACCACCCCCAGCTAATTTTTGTATTTTTAGTAGAGACAGGGTT TCACCTTGTTGGCCAGGCTGGTCTGAAACTCCTGACCTCAGGTGATCTGCCTGCCTCTGCCTCTCAAACA AAGTGCTGGGATTATAGGTATGAGCCACCATACCCGGCCCAGCTCCTTTAGATTTATTCCCTCTTATGGG ATGTTTTTAGAGTTCACGTAAGTGCATTGTTCCTTGGACCTCCTGTCTAGGCGTTCACTGCCAATCTGTA GGGTTGCCATTGGCTGTCAGGAAGAGTCCTGCACAGAGGGTCCTGTGCCCTGCAGATGCGATGGGGCGCT TCCTTCCTTTCTCATCCATTTATCTTTCAGTTCTCCTTTCCTATGTAAAGTGATGGTGGCATCACTTTTC TCCTTTATTCCATTAACTCAGAAAATTAACTGATTCAGAGCGTGCCTTCCTCCCCTCTCGCTCCACAACA CCACATAGCTCTGCAGCGGTCTCTTCCTAAGTGTTTGGTGGAACTTGCTGGTGAAGCCATCTAGATTGGG CCCAGCGGAAGGGCTGAGCTGCCAGGATGACCCCAAAGGGATGGGATGTTACAGTTGGGTCCTTGGGTCC TTGAAGGCCTTTGCTGCCCCAGGGCTGGATGGGGCAGAACCAGATTGTTGGGGCAGGGAAAAGAGGAAAA AAATGGCTGCTGGGGTGGAGGAACCGGCATGTCCAGCCCCTGCTGCTTTTCTCAGGGGTCACAGAGGAGG TGGTTGGGTGCAGGACAGGCCAGGGCCTGGGCGTTGCTGGCATTGACCATCCCTGTGTGATTGACAGCTG TAGCTGGAACCACTATAACATGCAGTACGCACTAGCAGTTTCCAAGCAGCGGGGCACAAAACGCTCCCTA GACCCGCTGGGAAGTGAGGAGGAGGCAGAAGCATCTGAAGATGACAGCCTGCATCTGCTTGGAGGAGGAG GCAGAGACTCAGAAGAAGAGATGCTGGCCTAGAGCCAGCCGGTTGCAGCGTTGGATTGTGCCGGCTAAGA CCTGCCAGGGAGATGGGACCCTTGTGCCACCTGGGCCAGCAAAGAGGAGGGGTCCAGAGAACAGCTGAAA TACTGTCACTAGTGGTAGTGACTTGCTTTTCCTGTGCACACATGTAGCCCATCAGGACAGCGAGCCGACG GGTCACGCCAGGGGCCGGCACGCACTGGCACCTGGCCCCAGGAGCGGGGCCGTGTGAACGGTGATGAATG TTGAAAATGCGTCTCAGAGAGGTATTCACATGAACTTTGTATGAGACTTATTTATATCTTTAACATAAAG GTTTGATAAAGAACTTAGGGATTAAAAAAAAGATGGAGTTTTCTAACGTGAGGATGAAGTCTACACTTCA GATTAAAAAGGGTTATGTTGTA Download Select all
Length	23892
OMIM ID	601475
HGNC ID	HGNC:9711
Unigene ID	Hs.449076
Ensembl ID	ENSG00000241945
PharmGKB ID	-

mRNA Information

mRNA ID	XM_011529667.1
Exon	join(1..145,1695..1807,6464..6558,6890..6989,7336..7479, 7975..8110,8402..8631,10531..10674,11474..11544, 12098..12234,13059..13207,13342..13489,13663..13813, 14888..15068,17291..17438,18722..18830,19611..19676, 20286..20571)
mRNA Sequence	>5822 GCGTGCTGTGGGCGGTGCCGCGCGGACCCCCGGGAAGTGTCTCTGTGGGCGGCCGCCGGGTTGA GCTGCGGCACACGTGCGACGGCCGTGATGAAGTTCGCTTACCGGTTTTCAAATTTGCTGGGTAC GGTGTACCGGCGTGGGAACCTAAATTTTACCTGCGATGGAAATTCAGTTATCAGTCCCGTGGGC AATAGAGTCACTGTATTTGACCTTAAAAACAACAAATCTGACACGCTGCCCCTGGCCACTCGGT ACAACGTCAAGTGCGTGGGGCTGTCCCCGGATGGCCGCCTCGCTATCATCGTCGATGAAGGGGG CGATGCGCTGCTGGTCAGCCTGGTCTGCAGGTCTGTGCTGCACCACTTCCACTTCAAGGGCTCT GTGCACAGTGTGTCCTTCTCCCCTGATGGCAGGAAGTTTGTTGTCACAAAGGGTAACATTGCCC AGATGTATCATGCCCCTGGGAAGAAGCGGGAGTTCAACGCCTTCGTTCTGGACAAGACCTATTT TGGGCCCTACGATGAGACCACCTGCATCGACTGGACGGATGACTCCAGGTGCTTTGTGGTTGGG AGCAAAGACATGTCCACCTGGGTGTTCGGAGCCGAGCGCTGGGACAACCTCATCTACTATGCAC TGGGGGGACATAAGGATGCCATCGTGGCCTGCTTCTTTGAATCCAACAGCCTGGACCTGTACTC ACTCAGCCAGGACGGAGTGCTGTGCATGTGGCAGTGTGACACGCCCCCCGAGGGCTTGCGGCTG AAGCCCCCTGCGGGCTGGAAAGCAGACCTGTTGCAGCGGGAGGAGGAAGAGGAGGAGGAGGAGG ACCAGGAGGGCGACAGAGAGACCACCATCCGGGGAAAAGCCACTCCGGCCGAGGAGGAGAAGAC AGGAAAAGTGAAGTACTCACGGCTGGCCAAGTACTTCTTCAATAAAGAAGGGGATTTTAACAAC CTGACAGCTGCAGCATTTCATAAGAAGTCTCACCTCTTGGTCACTGGCTTTGCTTCTGGAATCT TCCATCTTCATGAGCTGCCAGAGTTTAACCTCATCCACTCCCTGAGCATTTCAGATCAGAGCAT CGCCTCAGTGGCCATCAATAGCTCGGGGGACTGGATTGCTTTTGGCTGTTCAGGCCTGGGCCAG CTGCTGGTGTGGGAGTGGCAGAGTGAGTCCTACGTGCTCAAGCAGCAGGGCCACTTCAACAGCA TGGTGGCCCTGGCCTACTCGCCCGACGGACAGTACATCGTGACTGGCGGGGACGACGGCAAGGT CAAGGTGTGGAACACCCTCAGCGGCTTCTGCTTCGTCACTTTTACGGAGCACTCCAGCGGGGTG ACCGGTGTGACCTTTACTGCCACCGGCTACGTTGTGGTGACCTCATCCATGGACGGGACCGTGC GAGCCTTTGACCTTCACAGGTACCGAAACTTCCGCACCTTCACCTCTCCACGCCCCACCCAGTT CTCCTGTGTGGCGGTGGATGCGAGCGGTGAGATCGTCTCTGCAGGGGCGCAGGACTCCTTTGAG ATTTTCGTGTGGTCCATGCAGACAGGCAGGCTCCTTGATGTTTTGTCTGGACACGAAGGGCCCA TCAGTGGTCTGTGTTTTAACCCAATGAAGTCCGTCCTGGCCAGTGCCTCCTGGGACAAGACAGT GCGCCTATGGGACATGTTTGACAGCTGGAGGACCAAGGAGACGCTGGCCCTGACCTCTGATGCT CTGGCTGTGACTTTTCGCCCTGATGGTGCGGAGCTGGCTGTGGCCACACTGAACTCACAGATCA CCTTCTGGGACCCTGAGAACGCGGTGCAGACGGGCTCCATTGAGGGCAGGCATGACCTCAAGAC TGGCAGGAAGGAGCTGGACAAGATTACAGCCAAGCACGCGGCCAAGGGGAAGGCCTTCACCGCC CTGTGCTACTCTGCAGACGGCCACAGCATCCTGGCGGGAGGCATGTCCAAGTTCGTGTGCATCT ACCACGTCCGTGAGCAGATTCTCATGAAGAGGTTCGAGATCTCTTGCAACCTGTCTTTGGACGC CATGGAGGAATTTTTGAACCGAAGAAAAATGACAGAGTTTGGCAACCTGGCACTAATTGATCAG GATGCTGGGCAGGAGGATGGAGTCGCGATACCACTGCCAGGCGTCAGGAAAGGTGACATGAGTT CTCGGCACTTCAAACCTGAGATCAGGGTGACCTCACTCCGCTTCTCTCCCACTGGGCGCTGCTG GGCGGCCACCACCACGGAGGGACTCCTCATCTACTCCCTGGACACCCGCGTGCTCTTTGACCCG TTTGAGCTGGACACCAGCGTCACCCCCGGGAGGGTGCGCGAGGCACTGCGCCAGCAGGACTTCA CCAGGGCCATCCTCATGGCCCTCCGGCTCAACGAGAGCAAACTGGTGCAGGAGGCCCTGGAGGC GGTGCCCAGGGGCGAGATTGAAGTGGTCACCTCCTCCCTTCCTGAACTGTATGTGGAGAAAGTG CTGGAGTTTTTAGCTTCCTCCTTTGAAGTGTCTCGCCACCTGGAATTCTACCTCCTCTGGACTC ACAAACTGCTCATGTTGCACGGACAGAAGCTGAAGTCCAGAGCCGGGACGCTGCTGCCTGTCAT TCAGTTCCTCCAGAAGAGCATCCAGCGGCACCTGGACGACCTGTCGAAACTCTGTAGCTGGAAC CACTATAACATGCAGTACGCACTAGCAGTTTCCAAGCAGCGGGGCACAAAACGCTCCCTAGACC CGCTGGGAAGTGAGGAGGAGGCAGAAGCATCTGAAGATGACAGCCTGCATCTGCTTGGAGGAGG AGGCAGAGACTCAGAAGAAGAGATGCTGGCCTAGAGCCAGCCGGTTGCAGCGTTGGATTGTGCC GGCTAAGACCTGCCAGGGAGATGGGACCCTTGTGCCACCTGGGCCAGCAAAGAGGAGGGGTCCA GAGAACAGCTGAAATACTGTCACTAGTGGTAGTGACTTGCTTTTCCTGTGCACACATGTAGCCC ATCAGGACAGCGAGCCGACGGGTCACGCCAGGGGCCGGCACGCACTGGCACCTGGCCCCAGGAG CGGGGCCGTGTGAACGGTGATGAATGTTGAAAATGCGTCTCAGAGAGGTATTCACATGAACTTT GTATGAGACTTATTTATATCTTTAACATAAAGGTTTGATAAAGAACTTAGGGATTAAAAAAAAG ATGGAGTTTTCTAACGTGAGGATGAAGTCTACACTTCAGATTAAAAAGGGTTATGTTGTAAAAA AAAAAAAAAAAAA Download Select all
Length	3277

CDS Information

Location	join(128..145,1695..1807,6464..6558,6890..6989,7336..7479, 7975..8110,8402..8631,10531..10674,11474..11544, 12098..12234,13059..13207,13342..13489,13663..13813, 14888..15068,17291..17438,18722..18830,19611..19676, 20643..20861,20958..21108,21263..21337,23308..23482)
CDS Sequence	>gi\|48762925:91-2850 Homo sapiens PWP2 periodic tryptophan protein homolog (yeast) (PWP2), mRNA ATGAAGTTCGCTTACCGGTTTTCAAATTTGCTGGGTACGGTGTACCGGCGTGGGAACCTAAATTTTACCT GCGATGGAAATTCAGTTATCAGTCCCGTGGGCAATAGAGTCACTGTATTTGACCTTAAAAACAACAAATC TGACACGCTGCCCCTGGCCACTCGGTACAACGTCAAGTGCGTGGGGCTGTCCCCGGATGGCCGCCTCGCT ATCATCGTCGATGAAGGGGGCGATGCGCTGCTGGTCAGCCTGGTCTGCAGGTCTGTGCTGCACCACTTCC ACTTCAAGGGCTCTGTGCACAGTGTGTCCTTCTCCCCTGATGGCAGGAAGTTTGTTGTCACAAAGGGTAA CATTGCCCAGATGTATCATGCCCCTGGGAAGAAGCGGGAGTTCAACGCCTTCGTTCTGGACAAGACCTAT TTTGGGCCCTACGATGAGACCACCTGCATCGACTGGACGGATGACTCCAGGTGCTTTGTGGTTGGGAGCA AAGACATGTCCACCTGGGTGTTCGGAGCCGAGCGCTGGGACAACCTCATCTACTATGCACTGGGGGGACA TAAGGATGCCATCGTGGCCTGCTTCTTTGAATCCAACAGCCTGGACCTGTACTCACTCAGCCAGGACGGA GTGCTGTGCATGTGGCAGTGTGACACGCCCCCCGAGGGCTTGCGGCTGAAGCCCCCTGCGGGCTGGAAAG CAGACCTGTTGCAGCGGGAGGAGGAAGAGGAGGAGGAGGAGGACCAGGAGGGCGACAGAGAGACCACCAT CCGGGGAAAAGCCACTCCGGCCGAGGAGGAGAAGACAGGAAAAGTGAAGTACTCACGGCTGGCCAAGTAC TTCTTCAATAAAGAAGGGGATTTTAACAACCTGACAGCTGCAGCATTTCATAAGAAGTCTCACCTCTTGG TCACTGGCTTTGCTTCTGGAATCTTCCATCTTCATGAGCTGCCAGAGTTTAACCTCATCCACTCCCTGAG CATTTCAGATCAGAGCATCGCCTCAGTGGCCATCAATAGCTCGGGGGACTGGATTGCTTTTGGCTGTTCA GGCCTGGGCCAGCTGCTGGTGTGGGAGTGGCAGAGTGAGTCCTACGTGCTCAAGCAGCAGGGCCACTTCA ACAGCATGGTGGCCCTGGCCTACTCGCCCGACGGACAGTACATCGTGACTGGCGGGGACGACGGCAAGGT CAAGGTGTGGAACACCCTCAGCGGCTTCTGCTTCGTCACTTTTACGGAGCACTCCAGCGGGGTGACCGGT GTGACCTTTACTGCCACCGGCTACGTTGTGGTGACCTCATCCATGGACGGGACCGTGCGAGCCTTTGACC TTCACAGGTACCGAAACTTCCGCACCTTCACCTCTCCACGCCCCACCCAGTTCTCCTGTGTGGCGGTGGA TGCGAGCGGTGAGATCGTCTCTGCAGGGGCGCAGGACTCCTTTGAGATTTTCGTGTGGTCCATGCAGACA GGCAGGCTCCTTGATGTTTTGTCTGGACACGAAGGGCCCATCAGTGGTCTGTGTTTTAACCCAATGAAGT CCGTCCTGGCCAGTGCCTCCTGGGACAAGACAGTGCGCCTATGGGACATGTTTGACAGCTGGAGGACCAA GGAGACGCTGGCCCTGACCTCTGATGCTCTGGCTGTGACTTTTCGCCCTGATGGTGCGGAGCTGGCTGTG GCCACACTGAACTCACAGATCACCTTCTGGGACCCTGAGAACGCGGTGCAGACGGGCTCCATTGAGGGCA GGCATGACCTCAAGACTGGCAGGAAGGAGCTGGACAAGATTACAGCCAAGCACGCGGCCAAGGGGAAGGC CTTCACCGCCCTGTGCTACTCTGCAGACGGCCACAGCATCCTGGCGGGAGGCATGTCCAAGTTCGTGTGC ATCTACCACGTCCGTGAGCAGATTCTCATGAAGAGGTTCGAGATCTCTTGCAACCTGTCTTTGGACGCCA TGGAGGAATTTTTGAACCGAAGAAAAATGACAGAGTTTGGCAACCTGGCACTAATTGATCAGGATGCTGG GCAGGAGGATGGAGTCGCGATACCACTGCCAGGCGTCAGGAAAGGTGACATGAGTTCTCGGCACTTCAAA CCTGAGATCAGGGTGACCTCACTCCGCTTCTCTCCCACTGGGCGCTGCTGGGCGGCCACCACCACGGAGG GACTCCTCATCTACTCCCTGGACACCCGCGTGCTCTTTGACCCGTTTGAGCTGGACACCAGCGTCACCCC CGGGAGGGTGCGCGAGGCACTGCGCCAGCAGGACTTCACCAGGGCCATCCTCATGGCCCTCCGGCTCAAC GAGAGCAAACTGGTGCAGGAGGCCCTGGAGGCGGTGCCCAGGGGCGAGATTGAAGTGGTCACCTCCTCCC TTCCTGAACTGTATGTGGAGAAAGTGCTGGAGTTTTTAGCTTCCTCCTTTGAAGTGTCTCGCCACCTGGA ATTCTACCTCCTCTGGACTCACAAACTGCTCATGTTGCACGGACAGAAGCTGAAGTCCAGAGCCGGGACG CTGCTGCCTGTCATTCAGTTCCTCCAGAAGAGCATCCAGCGGCACCTGGACGACCTGTCGAAACTCTGTA GCTGGAACCACTATAACATGCAGTACGCACTAGCAGTTTCCAAGCAGCGGGGCACAAAACGCTCCCTAGA CCCGCTGGGAAGTGAGGAGGAGGCAGAAGCATCTGAAGATGACAGCCTGCATCTGCTTGGAGGAGGAGGC AGAGACTCAGAAGAAGAGATGCTGGCCTAG Download Select all
CCDS ID	CCDS33579.1

Protein Information

Protein ID	NP_005040.2
Protein Name	PWP2 periodic tryptophan protein homolog (yeast)
Molecular Wt. (Da)	102321
Protein Sequence	>5822 MKFAYRFSNLLGTVYRRGNLNFTCDGNSVISPVGNRVTVFDLKNNKSDTLPLATRYNVKCVGLS PDGRLAIIVDEGGDALLVSLVCRSVLHHFHFKGSVHSVSFSPDGRKFVVTKGNIAQMYHAPGKK REFNAFVLDKTYFGPYDETTCIDWTDDSRCFVVGSKDMSTWVFGAERWDNLIYYALGGHKDAIV ACFFESNSLDLYSLSQDGVLCMWQCDTPPEGLRLKPPAGWKADLLQREEEEEEEEDQEGDRETT IRGKATPAEEEKTGKVKYSRLAKYFFNKEGDFNNLTAAAFHKKSHLLVTGFASGIFHLHELPEF NLIHSLSISDQSIASVAINSSGDWIAFGCSGLGQLLVWEWQSESYVLKQQGHFNSMVALAYSPD GQYIVTGGDDGKVKVWNTLSGFCFVTFTEHSSGVTGVTFTATGYVVVTSSMDGTVRAFDLHRYR NFRTFTSPRPTQFSCVAVDASGEIVSAGAQDSFEIFVWSMQTGRLLDVLSGHEGPISGLCFNPM KSVLASASWDKTVRLWDMFDSWRTKETLALTSDALAVTFRPDGAELAVATLNSQITFWDPENAV QTGSIEGRHDLKTGRKELDKITAKHAAKGKAFTALCYSADGHSILAGGMSKFVCIYHVREQILM KRFEISCNLSLDAMEEFLNRRKMTEFGNLALIDQDAGQEDGVAIPLPGVRKGDMSSRHFKPEIR VTSLRFSPTGRCWAATTTEGLLIYSLDTRVLFDPFELDTSVTPGRVREALRQQDFTRAILMALR LNESKLVQEALEAVPRGEIEVVTSSLPELYVEKVLEFLASSFEVSRHLEFYLLWTHKLLMLHGQ KLKSRAGTLLPVIQFLQKSIQRHLDDLSKLCSWNHYNMQYALAVSKQRGTKRSLDPLGSEEEAE ASEDDSLHLLGGGGRDSEEEMLA Download Select all
Length	919
Uniprot ID	Q99062
Ensembl Protein ID	ENSP00000332180

Post-translational Modification Information (Source : HPRD)

Residue	Type	site
T	Phosphorylation	746
S	Phosphorylation	891
S	Phosphorylation	898
S	Phosphorylation	913
S	Phosphorylation	902
K	Acetylation	700
S	Phosphorylation	47
Y	Phosphorylation	632
S	Phosphorylation	744
T	Phosphorylation	791
S	Phosphorylation	792

Enzyme Information

No matching records could be found.

PPi Information

(Click to view network : Source STRING) View

Interactant Gene ID (Source: HPRD)	Gene Symbol	HPRD ID	Ref Seq ID	Technique	References
10040	TOM1L1	5266	NP_005477.2	yeast 2-hybrid	16169070

Pathway Information

Pathway Name	Pathway ID
Ribosome biogenesis in eukaryotes	hsa03008

Structure Information

No matching records could be found.

Domain Information

ID	Location	Description
cd00200	322-629	WD40
cl02567	322-629	WD40 superfamily
cd00200	292-571	WD40
cd00200	370-714	WD40
cd00200	291-529	WD40
pfam04003	770-875	Utp12
cl23538	770-875	Utp12 superfamily
cd00200	96-443	WD40
cl02567	96-443	WD40 superfamily
cd00200	58-401	WD40
smart00320	490-529	WD40
pfam00400	491-529	WD40
cd00200	35-216	WD40
cd00200	22-216	WD40
pfam00400	363-401	WD40
smart00320	362-401	WD40
cd14961	370-473	NHL_TRIM32_like
cl18310	370-473	NHL superfamily
cd14962	379-500	NHL_like_6
pfam00400	405-443	WD40
smart00320	404-443	WD40
cd05819	371-472	NHL
cd14957	339-472	NHL_like_2
cd05819	379-472	NHL
COG2319	33-574	WD40
COG2319	277-639	WD40
COG2319	370-746	WD40
COG2319	20-463	WD40
COG2319	374-739	WD40
PTZ00421	468-529	PTZ00421
PLN00181	394-530	PLN00181
PTZ00421	497-591	PTZ00421

Ontology Information

HPRD ID	1697
Molecular Class	Cell cycle control protein
Molecular Function	Protease inhibitor activity (GO:0030414)
Biological Process	Protein metabolism (GO:0019538)

SNP Information

View SNP Geneview Report

Drug Information

No matching records could be found.

External Links

ArrayExpress GO
ICGC GO
Cancer3D GO
COSMIC GO
NCG GO
TSGene GO
Tumor Gene Family of Databases GO
CCDB GO
G2SBC GO
Osteosarcoma Database GO
RCDB GO

ArrayExpress	GO
ICGC	GO
Cancer3D	GO
COSMIC	GO
NCG	GO
TSGene	GO
Tumor Gene Family of Databases	GO
CCDB	GO
G2SBC	GO
Osteosarcoma Database	GO
RCDB	GO