Search results:
General Information
| Gene_Symbol | Gene_ID | Gene_Name | Chromosome | Alias |
|---|---|---|---|---|
| RELB | 5971 | v-rel avian reticuloendotheliosis viral oncogene homolog B | 19 | REL-B |
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 16551621 | 2006 | Cell line : DLD-1, SW480, HT29 Source : - Sample Type : - No. of Sample : - Stage : - | SDS-PAGE and Western Blotting,ctive Rac Pulldown Assays and Immunoprecipitation,Confocal Immunofluorescence Microscopy,Luciferase Reporter Assay, | Up-regulation | - | The RelB pathway was reported to down-regulate canonical NF-kappaB activation during the inflammatory response, suggesting that increased levels of Rac1b in colorectal tumors may promote tumorigenesis. |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | - |
| Description | - |
| Chromosome | 19 |
| Location | 19q13.32 |
| Start | 45504707 |
| End | 45541456 |
| Strand | + |
| Gene Sequence | Download Select all |
| Length | 36750 |
| OMIM ID | 604758 |
| HGNC ID | HGNC:9956 |
| Unigene ID | Hs.654402 |
| Ensembl ID | ENSG00000104856 |
| PharmGKB ID | PA34322 |
mRNA Information
| mRNA ID | ?NM_006509.3 |
|---|---|
| Exon | join(1..237,1501..1548,8366..8374,10488..10828, 20605..20762,23881..23972,24158..24289,27440..27544, 31086..31301,32796..32864,33003..33080,35957..36750) | mRNA Sequence | Download Select all |
| Length | 2297 |
Protein Information
| Protein ID | NP_006500.2 |
|---|---|
| Protein Name | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| Molecular Wt. (Da) | 33641 |
| Protein Sequence | Download Select all |
| Length | 579 |
| Uniprot ID | Q04900 |
| Ensembl Protein ID | ENSP00000275080 |
Post-translational Modification Information (Source : HPRD)
| Residue | Type | site |
|---|---|---|
| S | Phosphorylation | 37 |
| S | Phosphorylation | 573 |
| S | Phosphorylation | 116 |
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
| Interactant Gene ID (Source: HPRD) | Gene Symbol | HPRD ID | Ref Seq ID | Technique | References |
|---|---|---|---|---|---|
| 4791 | NFKB2 | 1239 | NP_001070962.1 | in vivo | 1 250 599 017 962 800 |
| 23633 | KPNA6 | 9465 | NP_036448.1 | in vitro;in vivo | 14743216 |
Pathway Information
| Pathway Name | Pathway ID |
|---|---|
| Epstein-Barr virus infection | hsa05169 |
| HTLV-I infection | hsa05166 |
| MAPK signaling pathway | hsa04010 |
| NF-kappa B signaling pathway | hsa04064 |
| Osteoclast differentiation | hsa04380 |
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| cd07886 | 125-296 | RHD-n_RelB |
| cl08275 | 125-296 | RHD-n superfamily |
| cd01177 | 303-399 | IPT_NFkappaB |
| cl15674 | 303-399 | IPT superfamily |
| cd07827 | 125-296 | RHD-n |
| pfam00554 | 127-295 | RHD |
| cd07885 | 125-296 | RHD-n_RelA |
| cd07887 | 125-296 | RHD-n_Dorsal_Dif |
| cd07933 | 125-296 | RHD-n_c-Rel |
| cd07883 | 125-296 | RHD-n_NFkB |
| cd00602 | 303-399 | IPT_TF |
| cd07935 | 125-296 | RHD-n_NFkB1 |
| cd07934 | 125-296 | RHD-n_NFkB2 |
| cd07884 | 125-296 | RHD-n_Relish |
| smart00429 | 302-398 | IPT |
| cd00102 | 303-399 | IPT |
| cd01178 | 305-399 | IPT_NFAT |
Ontology Information
| HPRD ID | 4735 |
|---|---|
| Molecular Class | Transcription factor |
| Molecular Function | Receptor activity (GO:0004872) |
| Biological Process | Cell communication (GO:0007154); Signal transduction (GO:0007165) |
Drug Information
No matching records could be found.