Search results:
General Information
| Gene_Symbol | Gene_ID | Gene_Name | Chromosome | Alias |
|---|---|---|---|---|
| RPS4X | 6191 | ribosomal protein S4, X-linked | X | DXS306, CCG2, SCAR, SCR10, FLJ40595, RPS4, S4 |
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 21304002 | 2011 | Cell line : - Source : - Sample Type : Publicly available data from GenBank and Oncomine. Multiple case-matched normal and tumor tissues No. of Sample : - Stage : - | Meta analysis,RT-PCR. | Up-regulation | - | 9 (ECT2, ETV4, DDX21, RAN, S100A11, RPS4X, HSPD1, CKS2, and C9orf140) of the 34 candidate genes are expressed at significantly elevated levels in CRC tissues compared to normal tissues. |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | S ribosomal proteins |
| Description | Cytoplasmic ribosomes, organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes ribosomal protein S4, a component of the 40S subunit. Ribosomal protein S4 is the only ribosomal protein known to be encoded by more than one gene, namely this gene and ribosomal protein S4, Y-linked (RPS4Y). The 2 isoforms encoded by these genes are not identical, but are functionally equivalent. Ribosomal protein S4 belongs to the S4E family of ribosomal proteins. This gene is not subject to X-inactivation. It has been suggested that haploinsufficiency of the ribosomal protein S4 genes plays a role in Turner syndrome; however, this hypothesis is controversial. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008] |
| Chromosome | X |
| Location | Xq13.1 |
| Start | 71492453 |
| End | 71497141 |
| Strand | - |
| Gene Sequence | Download Select all |
| Length | 4689 |
| OMIM ID | 312760 |
| HGNC ID | HGNC:10424 |
| Unigene ID | Hs.118076 |
| Ensembl ID | ENSG00000198034 |
| PharmGKB ID | PA34839 |
mRNA Information
| mRNA ID | ?NM_001007.4 |
|---|---|
| Exon | join(1..99,1058..1135,1568..1748,2142..2239,3320..3491, 3903..4060,4520..4689) | mRNA Sequence | Download Select all |
| Length | 956 |
Protein Information
| Protein ID | NP_000998.1 |
|---|---|
| Protein Name | ribosomal protein S4, X-linked |
| Molecular Wt. (Da) | 82592 |
| Protein Sequence | Download Select all |
| Length | 263 |
| Uniprot ID | P56645 |
| Ensembl Protein ID | ENSP00000355031 |
Post-translational Modification Information (Source : HPRD)
| Residue | Type | site |
|---|---|---|
| T | Phosphorylation | 247 |
| K | Acetylation | 22 |
| K | Acetylation | 134 |
| K | Acetylation | 120 |
| T | Phosphorylation | 177 |
| T | Phosphorylation | 184 |
| S | Phosphorylation | 204 |
| S | Phosphorylation | 217 |
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
No matching records from HPRD source could be found.
Pathway Information
| Pathway Name | Pathway ID |
|---|---|
| Ribosome | hsa03010 |
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| cd06087 | 175-229 | KOW_RPS4 |
| cl00354 | 175-229 | KOW superfamily |
| cd00165 | 51-112 | S4 |
| cl09940 | 51-112 | S4 superfamily |
| pfam00900 | 94-170 | Ribosomal_S4e |
| cl03010 | 94-170 | Ribosomal_S4e superfamily |
| pfam08071 | Mar-40 | RS4NT |
| cl06900 | Mar-40 | RS4NT superfamily |
| smart00363 | 44-99 | S4 |
| PLN00036 | 1-260 | PLN00036 |
| PTZ00118 | 1-260 | PTZ00118 |
| COG1471 | 2-242 | RPS4A |
| PTZ00223 | 6-261 | PTZ00223 |
| PRK04313 | 5-239 | PRK04313 |
Ontology Information
| HPRD ID | 5098 |
|---|---|
| Molecular Class | Ribosomal subunit |
| Molecular Function | Sialyltransferase activity (GO:0008373) |
| Biological Process | Cell communication (GO:0007154); Signal transduction (GO:0007165) |
Drug Information
No matching records could be found.