Search results:
General Information
| Gene_Symbol | Gene_ID | Gene_Name | Chromosome | Alias |
|---|---|---|---|---|
| THADA | 63892 | thyroid adenoma associated | 2 | FLJ21877, KIAA1767, GITA |
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 21602532 | 2011 | Cell line : - Source : - Sample Type : Population based case-control study No. of Sample : 2011 CRC cases and 6049 controls Stage : - | SNP Selection and Genotyping | Polymorhpism | - | The strongest association was for the rs7578597 (THADA) Thr1187Ala missense polymorphism (P(trend)=0.004 adjusted for multiple testing), with the high risk allele for colorectal cancer being the low risk allele for diabetes. |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | - |
| Description | - |
| Chromosome | 2 |
| Location | 2p21 |
| Start | 43457975 |
| End | 43823185 |
| Strand | - |
| Gene Sequence | Download Select all |
| Length | 365211 |
| OMIM ID | 611800 |
| HGNC ID | HGNC:19217 |
| Unigene ID | Hs.369592 |
| Ensembl ID | ENSG00000115970 |
| PharmGKB ID | PA134882460 |
Protein Information
| Protein ID | NP_001077422.1 |
|---|---|
| Protein Name | thyroid adenoma associated |
| Molecular Wt. (Da) | 0 |
| Protein Sequence | Download Select all |
| Length | 1953 |
| Uniprot ID | P58166 |
| Ensembl Protein ID | ENSP00000266646 |
Post-translational Modification Information (Source : HPRD)
| Residue | Type | site |
|---|---|---|
| S | Phosphorylation | 1031 |
| S | Phosphorylation | 741 |
| S | Phosphorylation | 1031 |
| S | Phosphorylation | 1161 |
| S | Phosphorylation | 871 |
| S | Phosphorylation | 1161 |
| S | Phosphorylation | 943 |
| S | Phosphorylation | 653 |
| S | Phosphorylation | 943 |
| S | Phosphorylation | 1024 |
| S | Phosphorylation | 734 |
| S | Phosphorylation | 1024 |
| T | Phosphorylation | 1221 |
| Y | Phosphorylation | 1230 |
| T | Phosphorylation | 931 |
| Y | Phosphorylation | 940 |
| T | Phosphorylation | 1221 |
| Y | Phosphorylation | 1230 |
| S | Phosphorylation | 1339 |
| S | Phosphorylation | 1340 |
| S | Phosphorylation | 1339 |
| S | Phosphorylation | 1340 |
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
No matching records from HPRD source could be found.
Pathway Information
No matching records could be found.
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| pfam10350 | 945-1248 | DUF2428 |
| cl19897 | 945-1248 | DUF2428 superfamily |
| COG5543 | 394-1484 | COG5543 |
Ontology Information
| HPRD ID | 7565 |
|---|---|
| Molecular Class | Unclassified |
| Molecular Function | Ubiquitin-specific protease activity (GO:0004843) |
| Biological Process | Regulation of signal transduction (GO:0009966) |
Drug Information
No matching records could be found.