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General Information



Gene_Symbol Gene_ID Gene_Name Chromosome Alias
CREB3L2 64764 cAMP responsive element binding protein 3-like 2  7BBF2H7, TCAG_1951439 







  • Evidence
  • Gene
  • mRNA
  • CDS
  • Protein
  • PTM
  • Enzyme
  • PPi
  • Pathway
  • Structural
  • Domain
  • Ontology
  • SNP
  • Drug
  • External Links



Evidence Information


Pubmed ID Year Sample Information Techniques Mechanism Fold Change Remark
26133168   2015Cell line : HT-29 HDF

Source : LGC STANDARDS and Life technologies

Sample Type : -

No. of Sample : -

Stage : -

real time RT-PCR, Immunocytochemistry,Whole genome mRNA expression analysis Up-regulation--


Gene Details



NC_000007.13 (137559725..137686847, complement)

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Gene Type protein coding
Gene Family basic leucine zipper proteins
Description This gene encodes a member of the oasis bZIP transcription factor family. Members of this family can dimerize but form homodimers only. The encoded protein is a transcriptional activator. Translocations between this gene on chromosome 7 and the gene fused in sarcoma on chromosome 16 can be found in some tumors. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]  
Chromosome 7
Location 7q34
Start 137559725  
End 137686847  
Strand -  
Gene Sequence

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Length 127123  
OMIM ID 608834   
HGNC ID HGNC:23720   
Unigene ID Hs.490273   
Ensembl ID ENSG00000182158   
PharmGKB ID PA134914841   

mRNA Information


mRNA ID ?NM_001253775.1
Exon  
mRNA Sequence

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Length  



CDS Information


   
Location
CDS Sequence

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CCDS ID CCDS34760.1



Protein Information


      
Protein IDNP_001240704.1
Protein NamecAMP responsive element binding protein 3-like 2
Molecular Wt. (Da)0
Protein Sequence

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Length 520  
Uniprot IDQ8TD26
Ensembl Protein ID ENSP00000362319  



Post-translational Modification Information (Source : HPRD)


Residue Type site
SPhosphorylation191;-
TPhosphorylation232

Enzyme Information


No matching records could be found.

PPi Information


(Click to view network : Source STRING)      View   

No matching records from HPRD source could be found.

Pathway Information


                                                                                                                                                
Pathway Name Pathway ID
Adrenergic signaling in cardiomyocytes hsa04261
Alcoholism hsa05034
Aldosterone synthesis and secretion hsa04925
Amphetamine addiction hsa05031
AMPK signaling pathway hsa04152
cAMP signaling pathway hsa04024
cGMP-PKG signaling pathway hsa04022
Cholinergic synapse hsa04725
Cocaine addiction hsa05030
Dopaminergic synapse hsa04728
Estrogen signaling pathway hsa04915
Glucagon signaling pathway hsa04922
Hepatitis B hsa05161
Huntington's disease hsa05016
Insulin resistance hsa04931
Insulin secretion hsa04911
Longevity regulating pathway - mammal hsa04211
Melanogenesis hsa04916
PI3K-Akt signaling pathway hsa04151
Prostate cancer hsa05215
Thyroid hormone synthesis hsa04918
TNF signaling pathway hsa04668
Vasopressin-regulated water reabsorption hsa04962
Viral carcinogenesis hsa05203


Structure Information


No matching records could be found.

Domain Information




ID Location Description
cd14689305-348  bZIP_CREB3
cl21462305-348  bZIP superfamily
cd14704307-347  bZIP_HY5-like
cd14686307-348  bZIP
cd14706308-341  bZIP_CREBZF
pfam00170307-347  bZIP_1
smart00338305-348  BRLZ
cd14700307-343  bZIP_ATF6
cd12193307-348  bZIP_GCN4
cd14690307-343  bZIP_CREB1
pfam07716307-345  bZIP_2
cd14687308-345  bZIP_ATF2
cd14691305-348  bZIP_XBP1
cd14703305-348  bZIP_plant_RF2
cd14811307-338  bZIP_u2
cd14702307-344  bZIP_plant_GBF1
cd14709307-343  bZIP_CREBL2
cd14809308-342  bZIP_AUREO-like
cd14810305-347  bZIP_u1
cd14812307-337  bZIP_u3
cd14688308-348  bZIP_YAP
cd14705312-348  bZIP_Zip1
cd14701307-343  bZIP_BATF


Ontology Information


   
HPRD ID17507
Molecular ClassTranscription factor
Molecular FunctionMolecular function unknown (GO:0005554)
Biological ProcessBiological_process unknown (GO:0000004)  



SNP Information


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Drug Information


No matching records could be found.

External Links


                                 
ArrayExpressGO
ICGCGO
Cancer3DGO
COSMICGO
NCGGO
TSGeneGO
Tumor Gene Family of DatabasesGO
CCDBGO
G2SBCGO
Osteosarcoma DatabaseGO
RCDBGO