Search results:
General Information
| Gene_Symbol | Gene_ID | Gene_Name | Chromosome | Alias |
|---|---|---|---|---|
| BMPR2 | 659 | bone morphogenetic protein receptor, type II (serine/threonine kinase)  | 2 | BRK-3, T-ALK, BMPR3, BMPR-II  |
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 26247575    | 2015 | Cell line : - Source : Twin Cities Metropolitan Area, Kaiser Permanente Medical Care Program of Northern California (KPMCP) and a seven-county area of Utah. Sample Type : Population-based case-control study No. of Sample : Colon cancer 1,593 and controls 1,994 Stage : - | MMR immunohistochemistry, MSI analyses,Target gene analyses | Mutation | - | Mutations in microsatellite sequences (A)7 of BMPR2 and (A)8 of MSH3 were significantly more frequent in the distal CRC. |
| 21387313    | 2012 | Cell line : - Source : - Sample Type : CRC tumor No. of Sample : 129 Stage : TNM Stage I-IV | TagSNP Selection, Genotyping | Polymorhpism | - | BMPR2 rs2228545 was associated with an almost twofold increased risk of rectal cancer. |
Gene Details

| Gene Type | protein coding |
|---|---|
| Gene Family | - |
| Description | This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of two different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension, both familial and fenfluramine-associated, and with pulmonary venoocclusive disease. [provided by RefSeq, Jul 2008]   |
| Chromosome | 2 |
| Location | 2q33-q34 |
| Start | 203241033   |
| End | 203432474   |
| Strand | +   |
| Gene Sequence |    Download   Select all |
| Length | 191442   |
| OMIM ID | 600799    |
| HGNC ID | HGNC:1078    |
| Unigene ID | Hs.471119    |
| Ensembl ID | ENSG00000204217    |
| PharmGKB ID | PA25388    |
mRNA Information
| mRNA ID | XM_011511687.1 |
|---|---|
| Exon | join(1..1241,88500..88670,91210..91380,137410..137520, 138579..138670,142513..142743,143778..143892, 154485..154645,156276..156423,166002..166138, 176407..176579,178943..180222,183390..191442)   | mRNA Sequence |    Download   Select all |
| Length | 12084   |
CDS Information
| Location | |
|---|---|
| CDS Sequence |    Download   Select all |
| CCDS ID | CCDS33361.1 |    
Protein Information
| Protein ID | |
|---|---|
| Protein Name | bone morphogenetic protein receptor, type II (serine/threonine kinase) |
| Molecular Wt. (Da) | 0 |
| Protein Sequence |    Download   Select all |
| Length | 0   |
| Uniprot ID | P05164 |    
| Ensembl Protein ID | ENSP00000225275   |    
Post-translational Modification Information (Source : HPRD)
| Residue | Type | site |
|---|---|---|
| S | Phosphorylation | 1011;- |
| S | Phosphorylation | 1030;- |
| S | Phosphorylation | 862 |
| S | Phosphorylation | 863 |
| S | Phosphorylation | 586 |
| S | Phosphorylation | 513 |
| S | Phosphorylation | 513 |
| S | Phosphorylation | 757 |
| S | Phosphorylation | 680 |
| S | Phosphorylation | 681 |
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING)      View   
| Interactant Gene ID (Source: HPRD) | Gene Symbol | HPRD ID | Ref Seq ID | Technique | References |
|---|---|---|---|---|---|
| 650 |    BMP2 |    206 |    NP_001191.1 |    in vivo |    10880444    |
| 652 |    BMP4 |    207 |    NP_001193.2 |    in vitro;in vivo |    76   444   688   702   914    |
| 654 |    BMP6 |    211 |    NP_001709.1 |    in vivo |    11401330    |
| 655 |    BMP7 |    212 |    NP_001710.1 |    in vivo;yeast 2-hybrid |    7791754    |
| 722 |    C4BPA |    403 |    NP_000706.1 |    in vitro |    15188402    |
| 1066 |    CES1 |    268 |    NP_001020366.1 |    in vitro |    15188402    |
| 1326 |    MAP3K8 |    1863 |    NP_005195.2 |    in vitro |    15188402    |
| 1410 |    CRYAB |    428 |    NP_001876.1 |    in vitro |    15188402    |
| 4009 |    LMX1A |    2623 |    NP_796372.1 |    in vitro |    15188402    |
| 4046 |    LSP1 |    1083 |    NP_002330.1 |    in vitro |    15188402    |
| 4342 |    MOS |    1816 |    NP_005363.1 |    in vitro |    15188402    |
| 5579 |    PRKCB |    1499 |    NP_002729.2 |    in vitro |    15188402    |
| 11073 |    TOPBP1 |    9678 |    NP_008958.2 |    in vitro |    15188402    |
| 203068 |    TUBB |    1852 |    NP_001060.1 |    in vitro |    15188402    |
Pathway Information
| Pathway Name | Pathway ID |
|---|---|
| Cytokine-cytokine receptor interaction |    hsa04060 |    
| Hippo signaling pathway |    hsa04390 |    
| MicroRNAs in cancer |    hsa05206 |    
| Signaling pathways regulating pluripotency of stem cells |    hsa04550 |    
| TGF-beta signaling pathway |    hsa04350 |    
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| cd14054 | 207-504  | STKc_BMPR2_AMHR2 |
| cl21453 | 207-504  | PKc_like superfamily |
| cd13998 | 207-504  | STKc_TGFbR-like |
| cd14053 | 207-506  | STKc_ACVR2 |
| cd14055 | 207-504  | STKc_TGFbR2_like |
| cd14140 | 207-504  | STKc_ACVR2b |
| cd14056 | 207-504  | STKc_TGFbR_I |
| cd14141 | 207-504  | STKc_ACVR2a |
| cd14142 | 203-494  | STKc_ACVR1_ALK1 |
| cd14144 | 208-494  | STKc_BMPR1 |
| cd14143 | 207-494  | STKc_TGFbR1_ACVR1b_ACVR1c |
| cd14219 | 203-504  | STKc_BMPR1b |
| cd14220 | 209-504  | STKc_BMPR1a |
| cd13999 | 209-491  | STKc_MAP3K-like |
| cd00180 | 209-425  | PKc |
| cd00192 | 207-491  | PTKc |
| cd13979 | 199-494  | STKc_Mos |
| cd14058 | 209-505  | STKc_TAK1 |
| cd14066 | 209-417  | STKc_IRAK |
| cd14014 | 204-504  | STKc_PknB_like |
| cd13978 | 209-493  | STKc_RIP |
| cd06606 | 204-390  | STKc_MAPKKK |
| cd05038 | 201-491  | PTKc_Jak_rpt2 |
| cd14064 | 209-417  | PKc_TNNI3K |
| cd14060 | 210-491  | STKc_MLTK |
| cd06614 | 203-495  | STKc_PAK |
| cd05117 | 204-495  | STKc_CAMK |
| cd07838 | 204-428  | STKc_CDK4_6_like |
| cd05122 | 204-410  | PKc_STE |
| cd05033 | 198-416  | PTKc_EphR |
| cd05039 | 203-417  | PTKc_Csk_like |
| cd14059 | 209-416  | STKc_MAP3K12_13 |
| cd13985 | 202-418  | STKc_GAK_like |
| cd08215 | 204-495  | STKc_Nek |
| cd06627 | 202-391  | STKc_Cdc7_like |
| cd14065 | 209-451  | PKc_LIMK_like |
| cd14047 | 202-424  | STKc_EIF2AK2_PKR |
| cd05056 | 198-419  | PTKc_FAK |
| cd14664 | 209-427  | STK_BAK1_like |
| cd05123 | 209-499  | STKc_AGC |
| cd06629 | 207-494  | STKc_Bck1_like |
| cd14063 | 203-493  | PK_KSR |
| pfam01064 | 60-131  | Activin_recp |
| cl10471 | 60-131  | LU superfamily |
| cd05063 | 207-416  | PTKc_EphR_A2 |
| cd05083 | 198-456  | PTKc_Chk |
| cd14158 | 208-416  | STKc_IRAK4 |
| cd14027 | 274-500  | STKc_RIP1 |
| cd13996 | 200-421  | STKc_EIF2AK |
| cd05041 | 207-468  | PTKc_Fes_like |
| cd05032 | 198-416  | PTKc_InsR_like |
| cd13983 | 203-411  | STKc_WNK |
| cd14007 | 209-413  | STKc_Aurora |
| cd05080 | 203-493  | PTKc_Tyk2_rpt2 |
| cd14205 | 202-417  | PTKc_Jak2_rpt2 |
| cd13994 | 209-417  | STKc_HAL4_like |
| cd14154 | 237-419  | STKc_LIMK |
| cd05085 | 207-468  | PTKc_Fer |
| cd14222 | 237-416  | STKc_LIMK2 |
| cd07832 | 204-428  | STKc_CCRK |
| cd05082 | 197-482  | PTKc_Csk |
| cd05087 | 206-495  | PTKc_Aatyk1 |
| cd14155 | 209-467  | PKc_TESK |
| cd07829 | 206-428  | STKc_CDK_like |
| cd14003 | 202-412  | STKc_AMPK-like |
| cd14137 | 203-463  | STKc_GSK3 |
| cd05581 | 201-468  | STKc_PDK1 |
| cd05049 | 200-503  | PTKc_Trk |
| cd05065 | 198-491  | PTKc_EphR_B |
| cd13997 | 206-495  | PKc_Wee1_like |
| cd14002 | 201-418  | STKc_STK36 |
| cd05051 | 202-493  | PTKc_DDR |
| cd07833 | 201-495  | STKc_CDKL |
| cd05060 | 209-417  | PTKc_Syk_like |
| cd14098 | 205-412  | STKc_Rad53_Cds1 |
| cd06624 | 199-389  | STKc_ASK |
| cd07834 | 204-428  | STKc_MAPK |
| cd05081 | 202-420  | PTKc_Jak3_rpt2 |
| cd14008 | 209-434  | STKc_LKB1_CaMKK |
| cd07840 | 206-488  | STKc_CDK9_like |
| cd06917 | 206-517  | STKc_NAK1_like |
| cd14000 | 208-494  | STKc_LRRK |
| cd14033 | 209-495  | STKc_WNK4 |
| cd05066 | 198-416  | PTKc_EphR_A |
| cd13982 | 207-498  | STKc_IRE1 |
| cd08217 | 204-413  | STKc_Nek2 |
| cd06609 | 203-494  | STKc_MST3_like |
| cd08530 | 202-416  | STKc_CNK2-like |
| cd13993 | 202-432  | STKc_Pat1_like |
| cd06626 | 209-494  | STKc_MEKK4 |
| cd05579 | 209-502  | STKc_MAST_like |
| cd14156 | 209-421  | PKc_LIMK_like_unk |
| cd14046 | 206-495  | STKc_EIF2AK4_GCN2_rpt2 |
| cd06612 | 205-389  | STKc_MST1_2 |
| cd14061 | 208-416  | STKc_MLK |
| cd05611 | 206-415  | STKc_Rim15_like |
| cd14001 | 219-415  | PKc_TOPK |
| cd07841 | 206-428  | STKc_CDK7 |
| cd06608 | 205-411  | STKc_myosinIII_N_like |
| cd14221 | 232-419  | STKc_LIMK1 |
| cd06628 | 208-494  | STKc_Byr2_like |
| cd06610 | 201-389  | STKc_OSR1_SPAK |
| cd14152 | 203-491  | STKc_KSR1 |
| cd14026 | 206-419  | STKc_RIP2 |
| cd06648 | 195-495  | STKc_PAK_II |
| cd05057 | 203-417  | PTKc_EGFR_like |
| cd14050 | 206-390  | PKc_Myt1 |
| cd05072 | 201-493  | PTKc_Lyn |
| cd14010 | 202-418  | STKc_ULK4 |
| cd14062 | 209-417  | STKc_Raf |
| cd06623 | 201-495  | PKc_MAPKK_plant_like |
| cd05118 | 204-428  | STKc_CMGC |
| cd05061 | 201-464  | PTKc_InsR |
| cd07835 | 206-428  | STKc_CDK1_CdkB_like |
| cd05053 | 198-431  | PTKc_FGFR |
| cd14206 | 206-484  | PTKc_Aatyk3 |
| cd06632 | 207-494  | STKc_MEKK1_plant |
| cd05112 | 198-417  | PTKc_Itk |
| cd06638 | 195-416  | STKc_myosinIIIA_N |
| cd14048 | 200-416  | STKc_EIF2AK3_PERK |
| cd05097 | 203-462  | PTKc_DDR_like |
| cd14009 | 209-390  | STKc_ATG1_ULK_like |
| cd05079 | 203-495  | PTKc_Jak1_rpt2 |
| cd07845 | 206-428  | STKc_CDK10 |
| cd05035 | 203-505  | PTKc_TAM |
| cd14153 | 203-449  | PK_KSR2 |
| cd14150 | 203-416  | STKc_A-Raf |
| cd08529 | 205-495  | STKc_FA2-like |
| cd05048 | 200-417  | PTKc_Ror |
| cd14093 | 237-412  | STKc_PhKG |
| cd08220 | 208-416  | STKc_Nek8 |
| cd06630 | 207-398  | STKc_MEKK1 |
| cd05113 | 198-417  | PTKc_Btk_Bmx |
| cd14148 | 208-504  | STKc_MLK2 |
| cd05059 | 198-491  | PTKc_Tec_like |
| cd14025 | 277-495  | STKc_RIP4_like |
| cd06625 | 202-391  | STKc_MEKK3_like |
| cd06639 | 184-491  | STKc_myosinIIIB_N |
| cd07873 | 206-465  | STKc_PCTAIRE1 |
| cd14031 | 190-493  | STKc_WNK3 |
| cd05115 | 201-501  | PTKc_Zap-70 |
| cd05574 | 201-499  | STKc_phototropin_like |
| cd06613 | 204-411  | STKc_MAP4K3_like |
| cd06640 | 206-495  | STKc_MST4 |
| cd08528 | 202-497  | STKc_Nek10 |
| cd05084 | 207-419  | PTKc_Fes |
| cd13992 | 252-491  | PK_GC |
| cd07852 | 200-454  | STKc_MAPK15-like |
| cd05578 | 311-492  | STKc_Yank1 |
| cd05609 | 199-431  | STKc_MAST |
| cd05068 | 198-493  | PTKc_Frk_like |
| cd07870 | 206-506  | STKc_PFTAIRE2 |
| cd14030 | 178-491  | STKc_WNK1 |
| cd05580 | 201-413  | STKc_PKA_like |
| cd06605 | 201-416  | PKc_MAPKK |
| cd05092 | 209-493  | PTKc_TrkA |
| cd07842 | 209-497  | STKc_CDK8_like |
| cd14147 | 199-491  | STKc_MLK3 |
| cd07837 | 201-437  | STKc_CdkB_plant |
| cd05050 | 199-417  | PTKc_Musk |
| cd07860 | 202-428  | STKc_CDK2_3 |
| cd14096 | 202-416  | STKc_RCK1-like |
| cd05067 | 201-431  | PTKc_Lck_Blk |
| cd06646 | 202-387  | STKc_MAP4K5 |
| cd14099 | 207-412  | STKc_PLK |
| cd14663 | 204-389  | STKc_SnRK3 |
| cd05042 | 209-495  | PTKc_Aatyk |
| cd07861 | 206-497  | STKc_CDK1_euk |
| cd07863 | 209-428  | STKc_CDK4 |
| cd05613 | 202-417  | STKc_MSK1_N |
| cd14042 | 216-491  | PK_GC-A_B |
| cd05044 | 208-499  | PTKc_c-ros |
| cd13988 | 209-416  | STKc_TBK1 |
| cd14145 | 198-491  | STKc_MLK1 |
| cd05073 | 201-453  | PTKc_Hck |
| cd06647 | 206-416  | STKc_PAK_I |
| cd06642 | 206-495  | STKc_STK25 |
| cd05614 | 202-478  | STKc_MSK2_N |
| cd07843 | 201-428  | STKc_CDC2L1 |
| cd06641 | 203-495  | STKc_MST3 |
| cd14146 | 208-491  | STKc_MLK4 |
| cd07846 | 206-428  | STKc_CDKL2_3 |
| cd07839 | 206-429  | STKc_CDK5 |
| cd05040 | 207-417  | PTKc_Ack_like |
| cd14032 | 209-416  | STKc_WNK2_like |
| cd05099 | 201-431  | PTKc_FGFR4 |
| cd06633 | 206-424  | STKc_TAO3 |
| cd14151 | 209-476  | STKc_B-Raf |
| cd07855 | 201-429  | STKc_ERK5 |
| cd05034 | 209-493  | PTKc_Src_like |
| cd14004 | 206-417  | STKc_PASK |
| cd08224 | 202-415  | STKc_Nek6_7 |
| cd14068 | 208-501  | STKc_LRRK2 |
| cd14087 | 205-412  | STKc_PSKH1 |
| cd07836 | 202-463  | STKc_Pho85 |
| cd07864 | 200-419  | STKc_CDK12 |
| cd14012 | 254-460  | PK_eIF2AK_GCN2_rpt1 |
| cd07830 | 204-428  | STKc_MAK_like |
| cd05583 | 277-416  | STKc_MSK_N |
| cd05098 | 201-431  | PTKc_FGFR1 |
| cd05045 | 202-426  | PTKc_RET |
| cd05070 | 201-493  | PTKc_Fyn |
| cd06636 | 203-388  | STKc_MAP4K4_6_N |
| cd07879 | 206-499  | STKc_p38delta |
| cd07844 | 206-463  | STKc_PCTAIRE_like |
| cd08225 | 202-455  | STKc_Nek5 |
| cd05116 | 209-417  | PTKc_Syk |
| cd07871 | 206-431  | STKc_PCTAIRE3 |
| cd05148 | 205-431  | PTKc_Srm_Brk |
| cd07848 | 201-476  | STKc_CDKL5 |
| cd07853 | 209-449  | STKc_NLK |
| cd14202 | 207-388  | STKc_ULK1 |
| cd14162 | 209-390  | STKc_TSSK4-like |
| cd07869 | 201-426  | STKc_PFTAIRE1 |
| cd05064 | 198-416  | PTKc_EphR_A10 |
| cd13975 | 204-491  | PKc_Dusty |
| cd05091 | 198-417  | PTKc_Ror2 |
| cd14165 | 209-412  | STKc_TSSK1_2-like |
| cd14069 | 204-388  | STKc_Chk1 |
| cd13990 | 205-416  | STKc_TLK |
| cd13977 | 266-421  | STKc_PDIK1L |
| cd05573 | 201-417  | STKc_ROCK_NDR_like |
| cd14120 | 209-412  | STKc_ULK1_2-like |
| cd05046 | 202-417  | PTK_CCK4 |
| cd06615 | 303-411  | PKc_MEK |
| cd07850 | 206-426  | STKc_JNK |
| cd05612 | 201-416  | STKc_PRKX_like |
| cd13986 | 204-410  | STKc_16 |
| cd05110 | 203-474  | PTKc_HER4 |
| cd14080 | 205-412  | STKc_TSSK-like |
| cd07857 | 202-427  | STKc_MPK1 |
| cd14203 | 209-493  | PTKc_Src_Fyn_like |
| cd05074 | 203-508  | PTKc_Tyro3 |
| cd05075 | 203-476  | PTKc_Axl |
| cd14149 | 205-416  | STKc_C-Raf |
| cd06607 | 206-424  | STKc_TAO |
| cd05111 | 203-431  | PTK_HER3 |
| cd14204 | 198-505  | PTKc_Mer |
| cd05109 | 203-431  | PTKc_HER2 |
| cd14181 | 276-497  | STKc_PhKG2 |
| cd06659 | 209-495  | STKc_PAK6 |
| cd05100 | 194-431  | PTKc_FGFR3 |
| cd14072 | 202-414  | STKc_MARK |
| cd06620 | 198-390  | PKc_Byr1_like |
| cd06637 | 203-460  | STKc_TNIK |
| cd05094 | 209-417  | PTKc_TrkC |
| cd06635 | 206-424  | STKc_TAO1 |
| cd06653 | 202-390  | STKc_MEKK3_like_u1 |
| cd14159 | 209-416  | STKc_IRAK1 |
| cd07872 | 206-431  | STKc_PCTAIRE2 |
| cd14116 | 200-418  | STKc_Aurora-A |
| cd05095 | 227-495  | PTKc_DDR2 |
| cd14200 | 308-493  | STKc_CaMKK1 |
| cd05052 | 209-416  | PTKc_Abl |
| cd07862 | 209-428  | STKc_CDK6 |
| cd14095 | 208-412  | STKc_DCKL |
| cd13987 | 209-428  | STKc_SBK1 |
| cd14052 | 205-416  | PTKc_Wee1_fungi |
| cd14071 | 209-431  | STKc_SIK |
| cd06645 | 201-416  | STKc_MAP4K3 |
| cd06631 | 207-494  | STKc_YSK4 |
| cd14037 | 254-413  | STKc_NAK_like |
| cd06655 | 207-416  | STKc_PAK2 |
| cd13989 | 236-416  | STKc_IKK |
| cd06621 | 279-495  | PKc_Pek1_like |
| cd14084 | 208-412  | STKc_Chk2 |
| cd05096 | 203-491  | PTKc_DDR1 |
| cd07880 | 201-494  | STKc_p38gamma |
| cd07858 | 209-463  | STKc_TEY_MAPK |
| cd05108 | 203-474  | PTKc_EGFR |
| cd06656 | 206-416  | STKc_PAK3 |
| cd05055 | 201-463  | PTKc_PDGFR |
| cd05101 | 201-431  | PTKc_FGFR2 |
| cd05036 | 201-441  | PTKc_ALK_LTK |
| cd05105 | 223-462  | PTKc_PDGFR_alpha |
| cd05062 | 209-416  | PTKc_IGF-1R |
| cd05618 | 185-416  | STKc_aPKC_iota |
| cd06654 | 206-527  | STKc_PAK1 |
| cd14119 | 209-429  | STKc_LKB1 |
| cd06622 | 201-428  | PKc_PBS2_like |
| cd14049 | 206-417  | STKc_EIF2AK1_HRI |
| cd07878 | 206-497  | STKc_p38beta |
| cd14036 | 203-419  | STKc_GAK |
| cd06652 | 202-410  | STKc_MEKK2 |
| cd08228 | 200-416  | STKc_Nek6 |
| cd07874 | 206-426  | STKc_JNK3 |
| cd05605 | 305-468  | STKc_GRK4_like |
| cd14097 | 209-412  | STKc_STK33 |
| cd05624 | 156-432  | STKc_MRCK_beta |
| cd14199 | 310-420  | STKc_CaMKK2 |
| cd07866 | 200-450  | STKc_BUR1 |
| cd05047 | 207-464  | PTKc_Tie |
| cd06617 | 201-464  | PKc_MKK3_6 |
| cd06634 | 206-424  | STKc_TAO2 |
| cd05071 | 201-493  | PTKc_Src |
| cd05086 | 209-495  | PTKc_Aatyk2 |
| cd07849 | 201-455  | STKc_ERK1_2_like |
| cd05577 | 277-416  | STKc_GRK |
| cd14073 | 205-390  | STKc_NUAK |
| cd07851 | 206-427  | STKc_p38 |
| cd05089 | 201-464  | PTKc_Tie1 |
| cd05093 | 202-417  | PTKc_TrkB |
| cd07876 | 200-463  | STKc_JNK2 |
| cd06658 | 209-416  | STKc_PAK5 |
| cd14182 | 207-417  | STKc_PhKG1 |
| cd14106 | 272-412  | STKc_DRAK |
| cd05106 | 303-456  | PTKc_CSF-1R |
| cd14118 | 311-493  | STKc_CAMKK |
| cd08221 | 209-420  | STKc_Nek9 |
| cd05595 | 277-423  | STKc_PKB_beta |
| cd05069 | 201-493  | PTKc_Yes |
| cd14207 | 308-504  | PTKc_VEGFR1 |
| cd06616 | 201-462  | PKc_MKK4 |
| cd05572 | 209-416  | STKc_cGK |
| cd06611 | 209-388  | STKc_SLK_like |
| cd14067 | 209-501  | STKc_LRRK1 |
| cd14121 | 207-416  | STKc_ULK3 |
| cd07875 | 206-493  | STKc_JNK1 |
| cd05584 | 206-413  | STKc_p70S6K |
| cd05594 | 189-423  | STKc_PKB_alpha |
| cd05037 | 272-492  | PTK_Jak_rpt1 |
| cd07877 | 206-426  | STKc_p38alpha |
| cd14045 | 220-430  | PK_GC_unk |
| cd08219 | 205-421  | STKc_Nek3 |
| cd05103 | 331-505  | PTKc_VEGFR2 |
| cd05088 | 196-431  | PTKc_Tie2 |
| cd14057 | 277-419  | PK_ILK |
| cd05608 | 301-416  | STKc_GRK1 |
| cd05596 | 201-389  | STKc_ROCK |
| cd06644 | 199-416  | STKc_STK10 |
| cd14090 | 207-412  | STKc_Mnk |
| cd06650 | 201-411  | PKc_MEK1 |
| cd05597 | 201-458  | STKc_DMPK_like |
| cd14117 | 198-418  | STKc_Aurora-B_like |
| cd13968 | 209-353  | PKc_like |
| cd07865 | 199-419  | STKc_CDK9 |
| cd05043 | 201-416  | PTK_Ryk |
| cd14018 | 248-497  | STKc_PINK1 |
| cd14006 | 209-412  | STKc_MLCK-like |
| cd05114 | 198-493  | PTKc_Tec_Rlk |
| cd05630 | 305-416  | STKc_GRK6 |
| cd06643 | 311-494  | STKc_SLK |
| cd07859 | 310-477  | STKc_TDY_MAPK |
| cd05602 | 196-417  | STKc_SGK1 |
| cd05632 | 305-416  | STKc_GRK5 |
| cd14166 | 205-414  | STKc_CaMKI_gamma |
| cd06649 | 303-416  | PKc_MEK2 |
| cd05601 | 274-388  | STKc_CRIK |
| cd14169 | 303-412  | STKc_CaMKI_beta |
| cd14041 | 196-415  | STKc_TLK2 |
| cd05619 | 276-459  | STKc_nPKC_theta |
| cd05054 | 201-493  | PTKc_VEGFR |
| cd05586 | 209-416  | STKc_Sck1_like |
| cd14161 | 204-427  | STKc_NUAK2 |
| cd05617 | 189-416  | STKc_aPKC_zeta |
| cd14201 | 207-388  | STKc_ULK2 |
| cd05589 | 278-431  | STKc_PKN |
| cd05631 | 323-416  | STKc_GRK4 |
| cd06619 | 202-390  | PKc_MKK5 |
| cd07847 | 206-498  | STKc_CDKL1_4 |
| cd05570 | 308-431  | STKc_PKC |
| cd05090 | 198-451  | PTKc_Ror1 |
| cd14044 | 197-491  | PK_GC-C |
| cd14079 | 202-430  | STKc_AMPK_alpha |
| cd14186 | 201-387  | STKc_PLK4 |
| cd05599 | 274-415  | STKc_NDR_like |
| cd05610 | 200-362  | STKc_MASTL |
| cd05593 | 199-423  | STKc_PKB_gamma |
| cd14039 | 209-474  | STKc_IKK_alpha |
| cd07854 | 225-434  | STKc_MAPK4_6 |
| cd14192 | 207-431  | STKc_MLCK3 |
| cd05102 | 331-505  | PTKc_VEGFR3 |
| cd06651 | 277-417  | STKc_MEKK3 |
| cd14131 | 206-493  | PKc_Mps1 |
| cd05582 | 329-388  | STKc_RSK_N |
| cd14076 | 205-412  | STKc_Kin4 |
| cd08222 | 311-416  | STKc_Nek11 |
| cd05603 | 207-417  | STKc_SGK2 |
| cd14163 | 209-441  | STKc_TSSK3-like |
| cd14016 | 204-357  | STKc_CK1 |
| cd05622 | 201-443  | STKc_ROCK1 |
| cd05607 | 308-416  | STKc_GRK7 |
| cd14133 | 204-435  | PKc_DYRK_like |
| cd05604 | 206-417  | STKc_SGK3 |
| cd05104 | 291-493  | PTKc_Kit |
| cd14081 | 209-390  | STKc_BRSK1_2 |
| cd05600 | 331-415  | STKc_Sid2p_like |
| cd05120 | 206-356  | APH_ChoK_like |
| cd14185 | 243-414  | STKc_DCKL3 |
| cd05620 | 276-418  | STKc_nPKC_delta |
| cd14082 | 207-425  | STKc_PKD |
| cd05592 | 278-416  | STKc_nPKC_theta_like |
| cd05621 | 201-432  | STKc_ROCK2 |
| cd14075 | 209-430  | STKc_NIM1 |
| cd14085 | 308-412  | STKc_CaMKIV |
| cd14164 | 204-412  | STKc_TSSK6-like |
| cd06618 | 199-389  | PKc_MKK7 |
| cd14174 | 207-494  | STKc_Mnk1 |
| cd14077 | 251-390  | STKc_Kin1_2 |
| cd05623 | 198-432  | STKc_MRCK_alpha |
| TIGR03724 | 208-355  | arch_bud32 |
| cd06657 | 209-416  | STKc_PAK4 |
| cd14086 | 201-412  | STKc_CaMKII |
| cd14188 | 308-418  | STKc_PLK2 |
| cd05590 | 276-417  | STKc_nPKC_eta |
| cd14078 | 275-390  | STKc_MELK |
| cd14111 | 310-392  | STKc_SPEG_rpt2 |
| cd14038 | 276-389  | STKc_IKK_beta |
| cd05107 | 331-491  | PTKc_PDGFR_beta |
| cd14083 | 201-412  | STKc_CaMKI |
| cd14209 | 201-413  | STKc_PKA |
| cd14109 | 207-412  | PK_Unc-89_rpt1 |
| cd14074 | 205-418  | STKc_SNRK |
| cd05571 | 278-420  | STKc_PKB |
| cd14197 | 303-414  | STKc_DRAK1 |
| cd14040 | 196-415  | STKc_TLK1 |
| cd14198 | 274-412  | STKc_DRAK2 |
| cd05591 | 305-416  | STKc_nPKC_epsilon |
| cd05598 | 331-388  | STKc_LATS |
| cd08229 | 200-444  | STKc_Nek7 |
| cd14193 | 207-425  | STKc_MLCK4 |
| cd14160 | 209-420  | PK_IRAK3 |
| cd07867 | 209-417  | STKc_CDC2L6 |
| cd14020 | 305-417  | STKc_KIS |
| cd14662 | 209-388  | STKc_SnRK2 |
| cd05575 | 209-415  | STKc_SGK |
| cd14089 | 268-412  | STKc_MAPKAPK |
| cd14173 | 274-494  | STKc_Mnk2 |
| cd14104 | 207-465  | STKc_Titin |
| cd07856 | 306-465  | STKc_Sty1_Hog1 |
| cd14189 | 208-388  | STKc_PLK3 |
| cd14115 | 209-390  | STKc_Kalirin_C |
| cd13991 | 276-390  | STKc_NIK |
| cd14094 | 201-440  | STKc_CASK |
| cd05606 | 305-388  | STKc_beta_ARK |
| cd14070 | 209-388  | STKc_HUNK |
| cd08218 | 209-416  | STKc_Nek1 |
| cd14225 | 205-440  | PKc_DYRK4 |
| cd14005 | 204-281  | STKc_PIM |
| cd14011 | 306-424  | PK_SCY1_like |
| cd05588 | 311-416  | STKc_aPKC |
| cd14223 | 277-392  | STKc_GRK2 |
| cd14190 | 202-425  | STKc_MLCK2 |
| cd14171 | 272-420  | STKc_MAPKAPK5 |
| cd07868 | 209-417  | STKc_CDK8 |
| pfam00069 | 203-497  | Pkinase |
| smart00220 | 204-495  | S_TKc |
| smart00221 | 203-498  | STYKc |
| pfam07714 | 203-499  | Pkinase_Tyr |
| smart00219 | 203-498  | TyrKc |
| COG0515 | 202-599  | SPS1 |
| PTZ00024 | 188-427  | PTZ00024 |
| PTZ00036 | 184-452  | PTZ00036 |
| PLN00009 | 200-428  | PLN00009 |
| PRK13184 | 286-416  | pknD |
| PLN00034 | 193-386  | PLN00034 |
| TIGR03903 | 252-415  | TOMM_kin_cyc |
| PTZ00263 | 200-416  | PTZ00263 |
| PTZ00267 | 276-417  | PTZ00267 |
| PTZ00266 | 200-416  | PTZ00266 |
| PTZ00426 | 190-433  | PTZ00426 |
| PHA03210 | 211-425  | PHA03210 |
| PRK09605 | 207-356  | PRK09605 |
| PTZ00283 | 324-431  | PTZ00283 |
| PHA02988 | 199-420  | PHA02988 |
Ontology Information
| HPRD ID | 3069 |    
|---|---|
| Molecular Class | Receptor serine/threonine kinase |
| Molecular Function | Molecular function unknown (GO:0005554) |
| Biological Process | Cell communication (GO:0007154); Signal transduction (GO:0007165)   |
Drug Information
No matching records could be found.
External Links
| ArrayExpress | GO |    
|---|---|
| ICGC | GO |    
| Cancer3D | GO |    
| COSMIC | GO |    
| NCG | GO |    
| TSGene | GO |    
| Tumor Gene Family of Databases | GO |    
| CCDB | GO |    
| G2SBC | GO |    
| Osteosarcoma Database | GO |    
| RCDB | GO |    
