Search results:
General Information
| Gene_Symbol | Gene_ID | Gene_Name | Chromosome | Alias |
|---|---|---|---|---|
| SMARCC1 | 6599 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | 3 | BAF155, SRG3, Rsc8, CRACC1 |
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 19156145 | 2009 | Cell line : - Source : - Sample Type : CRC tumor and normal tissue No. of Sample : 444 patients, 20 adjacent normal mucosa and 424 primary colorectal carcinomas Stage : stage I-III | Microarray-based transcript profiles, immunohistochemistry,Real-time RT- PCR | Up-regulation | - | High levels of CBFB and SMARCC1 proteins had a significantly better overall survival rate (P=0.0001 and P=0.0275, respectively) than patients with low levels. |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | - |
| Description | The protein encoded by this gene is a member of the SWI/SNF family of proteins, whose members display helicase and ATPase activities and which are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI and contains a predicted leucine zipper motif typical of many transcription factors. [provided by RefSeq, Jul 2008] |
| Chromosome | 3 |
| Location | 3p21.31 |
| Start | 47627378 |
| End | 47823405 |
| Strand | - |
| Gene Sequence | Download Select all |
| Length | 196028 |
| OMIM ID | 601732 |
| HGNC ID | HGNC:11104 |
| Unigene ID | Hs.476179 |
| Ensembl ID | ENSG00000173473 |
| PharmGKB ID | PA35954 |
mRNA Information
| mRNA ID | ?NM_003074.3 |
|---|---|
| Exon | join(1..313,8980..9099,35923..36008,43806..43887, 45790..45882,52822..52891,61181..61250,67426..67501, 71108..71233,75386..75507,80514..80638,88616..88675, 92492..92529,95746..95867,101408..101479,103605..103718, 105134..105287,106328..106441,111199..111258, 119324..119582,120461..120622,143136..143191, 145780..145894,146572..146726,159575..159709, 171589..171850,191079..191255,193610..196028) | mRNA Sequence | Download Select all |
| Length | 5780 |
Protein Information
| Protein ID | NP_003065.3 |
|---|---|
| Protein Name | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 |
| Molecular Wt. (Da) | 14329 |
| Protein Sequence | Download Select all |
| Length | 1105 |
| Uniprot ID | P24001 |
| Ensembl Protein ID | ENSP00000008180 |
Post-translational Modification Information (Source : HPRD)
| Residue | Type | site |
|---|---|---|
| S | Phosphorylation | 328 |
| S | Phosphorylation | 330 |
| S | Phosphorylation | 395 |
| T | Phosphorylation | 335 |
| S | Phosphorylation | 310;- |
| S | Phosphorylation | 328;- |
| S | Phosphorylation | 330;- |
| T | Phosphorylation | 337;- |
| S | Phosphorylation | 357 |
| T | Phosphorylation | 404 |
| S | Phosphorylation | 573 |
| S | Phosphorylation | 339 |
| S | Phosphorylation | 319 |
| K | Acetylation | 345 |
| K | Acetylation | 346 |
| K | Acetylation | 354 |
| K | Acetylation | 359 |
| K | Acetylation | 948 |
| K | Acetylation | 608 |
| S | Phosphorylation | 822 |
| S | Phosphorylation | 825 |
| S | Phosphorylation | 830 |
| T | Phosphorylation | 398 |
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
| Interactant Gene ID (Source: HPRD) | Gene Symbol | HPRD ID | Ref Seq ID | Technique | References |
|---|---|---|---|---|---|
| 898 | CCNE1 | 455 | NP_001229.1 | in vitro;in vivo | 9891079 |
| 1051 | CEBPB | 1801 | NP_005185.2 | in vivo | 10619021 |
| 2908 | NR3C1 | 679 | NP_001019265.1 | in vitro | 9590696 |
| 5971 | RELB | 6886 | NP_006500.2 | in vitro | 14743216 |
Pathway Information
No matching records could be found.
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| cd00024 | 216-251 | CHROMO |
| cl17459 | 216-251 | CHROMO superfamily |
| pfam04433 | 449-537 | SWIRM |
| cl04515 | 449-537 | SWIRM superfamily |
| smart00298 | 215-250 | CHROMO |
| COG5259 | 444-710 | RSC8 |
| COG5271 | 272-447 | MDN1 |
Ontology Information
| HPRD ID | 4676 |
|---|---|
| Molecular Class | Transcription factor |
| Molecular Function | Cytokine activity (GO:0005125) |
| Biological Process | Immune response (GO:0006955) |
Drug Information
No matching records could be found.