Search results:
General Information
| Gene_Symbol | Gene_ID | Gene_Name | Chromosome | Alias |
|---|---|---|---|---|
| BSG | 682 | basigin (Ok blood group)  | 19 | EMMPRIN, CD147  |
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 22782346    | 2012 | Cell line : - Source : - Sample Type : CRC tumor and Normal tissue No. of Sample : 277 Stage : TNM Stage III | immunohistochemistry and western blotting | Up-regulation | - | EMMPRIN is a promising prognostic biomarker in colorectal cancer. It could be used in the selection of stage III patients for adjuvant therapy. EMMPRIN expression was associated with shorter metastasis-free, disease-specific and overall survival in both univariate and multivariate analyses. |
Gene Details

| Gene Type | protein coding |
|---|---|
| Gene Family | CD molecules, "Blood group antigens", "Immunoglobulin superfamily / I-set domain containing", "Immunoglobulin superfamily / Immunoglobulin-like domain containing" |
| Description | The protein encoded by this gene is a plasma membrane protein that is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. The encoded protein is also a member of the immunoglobulin superfamily. Multiple transcript variants encoding different isoforms have been found for this gene.   |
| Chromosome | 19 |
| Location | 19p13.3 |
| Start | 571277   |
| End | 583493   |
| Strand | +   |
| Gene Sequence |    Download   Select all |
| Length | 12217   |
| OMIM ID | 109480    |
| HGNC ID | HGNC:1116    |
| Unigene ID | Hs.501293    |
| Ensembl ID | ENSG00000172270    |
| PharmGKB ID | -    |
mRNA Information
| mRNA ID | NM_198590.2 |
|---|---|
| Exon | join(1..303,8224..8380,9103..9185,9370..9506,10039..10315, 11030..11054,11238..11306,11474..12217)   | mRNA Sequence |    Download   Select all |
| Length | 2107   |
CDS Information
| Location | join(272..303,9103..9185,9370..9506,10039..10315, 11030..11054,11238..11301) |
|---|---|
| CDS Sequence |    Download   Select all |
| CCDS ID | CCDS12032.1 |    
Protein Information
| Protein ID | NP_001719.2 |
|---|---|
| Protein Name | basigin (Ok blood group) |
| Molecular Wt. (Da) | 40201 |
| Protein Sequence |    Download   Select all |
| Length | 385   |
| Uniprot ID | P43220 |    
| Ensembl Protein ID | ENSP00000362353   |    
Post-translational Modification Information (Source : HPRD)
| Residue | Type | site |
|---|---|---|
| S | Phosphorylation | 362;- |
| S | Phosphorylation | 246;- |
| S | Phosphorylation | 153;- |
| S | Phosphorylation | 182;- |
| S | Phosphorylation | 368;- |
| S | Phosphorylation | 252;- |
| S | Phosphorylation | 159;- |
| S | Phosphorylation | 188;- |
| N | Glycosylation | 160 |
| N | Glycosylation | 44 |
| N | Glycosylation | 268 |
| N | Glycosylation | 152 |
| N | Glycosylation | 59 |
| N | Glycosylation | 88 |
| S | Phosphorylation | 367 |
| S | Phosphorylation | 251 |
| S | Phosphorylation | 158 |
| S | Phosphorylation | 187 |
| S | Phosphorylation | 279 |
| S | Phosphorylation | 163 |
| S | Phosphorylation | 70 |
| S | Phosphorylation | 99 |
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING)      View   
| Interactant Gene ID (Source: HPRD) | Gene Symbol | HPRD ID | Ref Seq ID | Technique | References |
|---|---|---|---|---|---|
| 857 |    CAV1 |    3028 |    NP_001744.2 |    in vivo |    15201341    |
| 9260 |    PDLIM7 |    10436 |    NP_005442.2 |    yeast 2-hybrid |    16189514    |
Pathway Information
No matching records could be found.
Structure Information
| PDB ID | 3B5H |
|---|---|
| Resolution | 2.8 |
| Method | X-RAY DIFFRACTION |
| Chains | A, B   |
| Molecule | Cervical EMMPRIN   |
| Model | View |
Domain Information
| ID | Location | Description |
|---|---|---|
| cd00096 | 40-114  | Ig |
| cl11960 | 40-114  | Ig superfamily |
| cd05758 | 219-317  | Ig5_KIRREL3-like |
| cl11960 | 219-317  | Ig superfamily |
| cd05729 | 36-112  | Ig2_FGFR_like |
| pfam00047 | 37-110  | ig |
| pfam13895 | 228-318  | Ig_2 |
| cd05856 | 34-112  | Ig2_FGFRL1-like |
| pfam13927 | 29-112  | Ig_3 |
| cd04968 | 36-117  | Ig3_Contactin_like |
| cd05732 | 234-318  | Ig5_NCAM-1_like |
| cd00096 | 238-315  | Ig |
| cd05725 | 40-112  | Ig3_Robo |
| cd05870 | 234-311  | Ig5_NCAM-2 |
| cd05763 | 41-112  | Ig_1 |
| pfam13895 | 35-114  | Ig_2 |
| cd05722 | 37-125  | Ig1_Neogenin |
| cd05745 | 37-112  | Ig3_Peroxidasin |
| cd05898 | 219-317  | Ig5_KIRREL3 |
| cd05732 | 37-112  | Ig5_NCAM-1_like |
| cd05870 | 37-112  | Ig5_NCAM-2 |
| cd04978 | 37-112  | Ig4_L1-NrCAM_like |
| cd05869 | 40-112  | Ig5_NCAM-1 |
| cd05866 | 235-318  | Ig1_NCAM-2 |
| cd05728 | 36-112  | Ig4_Contactin-2-like |
| cd05739 | 37-56  | Ig3_RPTP_IIa_LAR_like |
| cd05895 | 239-312  | Ig_Pro_neuregulin-1 |
| cd00099 | 232-301  | IgV |
| cd05764 | 37-112  | Ig_2 |
| cd05748 | 39-113  | Ig_Titin_like |
| cd04977 | 222-311  | Ig1_NCAM-1_like |
| cd05743 | 37-112  | Ig_Perlecan_D2_like |
| smart00410 | 228-318  | IG_like |
| smart00408 | 37-112  | IGc2 |
| smart00409 | 228-318  | IG |
| smart00410 | 29-113  | IG_like |
| smart00409 | 29-113  | IG |
| pfam07679 | 25-112  | I-set |
| pfam07679 | 232-318  | I-set |
| smart00408 | 234-308  | IGc2 |
Ontology Information
| HPRD ID | 714 |    
|---|---|
| Molecular Class | Cell surface receptor |
| Molecular Function | Catalytic activity (GO:0003824) |
| Biological Process | Metabolism (GO:0008152); Energy pathways (GO:0006091)   |
Drug Information
No matching records could be found.
External Links
| ArrayExpress | GO |    
|---|---|
| ICGC | GO |    
| Cancer3D | GO |    
| COSMIC | GO |    
| NCG | GO |    
| TSGene | GO |    
| Tumor Gene Family of Databases | GO |    
| CCDB | GO |    
| G2SBC | GO |    
| Osteosarcoma Database | GO |    
| RCDB | GO |    
